| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Erica Butti, Melania Cusimano, Marco Bacigaluppi, Gianvito Martin. Neurogenic and non-neurogenic functions of endogenous neural stem cells. Frontiers in neuroscience. vol 8. 2014-06-24. PMID:24808821. |
adult neurogenesis is a lifelong process that occurs in two main neurogenic niches of the brain, namely in the subventricular zone (svz) of the lateral ventricles and in the subgranular zone (sgz) of the dentate gyrus (dg) in the hippocampus. |
2014-06-24 |
2023-08-13 |
Not clear |
| E Kádár, G Huguet, L Aldavert-Vera, I Morgado-Bernal, P Segura-Torre. Intracranial self stimulation upregulates the expression of synaptic plasticity related genes and Arc protein expression in rat hippocampus. Genes, brain, and behavior. vol 12. issue 8. 2014-06-23. PMID:23898803. |
immunofluorescence results showed that icss treatment induced a significant increase in arc protein expression in ca1 and dg hippocampal subfields. |
2014-06-23 |
2023-08-12 |
rat |
| Munder Zagaar, An Dao, Ibrahim Alhaider, Karim Alkadh. Regular treadmill exercise prevents sleep deprivation-induced disruption of synaptic plasticity and associated signaling cascade in the dentate gyrus. Molecular and cellular neurosciences. vol 56. 2014-06-20. PMID:23911794. |
the dentate gyrus (dg) area of the hippocampus is a key staging area for learning and memory processes and is particularly sensitive to sleep deprivation. |
2014-06-20 |
2023-08-12 |
Not clear |
| Elias Pavlopoulos, Sidonie Jones, Stylianos Kosmidis, Maggie Close, Carla Kim, Olga Kovalerchik, Scott A Small, Eric R Kande. Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48. Science translational medicine. vol 5. issue 200. 2014-06-20. PMID:23986399. |
together, these findings show that the dg is a hippocampal subregion targeted by aging, and identify molecular mechanisms of cognitive aging that could serve as valid targets for therapeutic intervention. |
2014-06-20 |
2023-08-12 |
mouse |
| Seyed Asaad Karimi, Iraj Salehi, Alireza Komaki, Abdolrahman Sarihi, Mohammad Zarei, Siamak Shahid. Effect of high-fat diet and antioxidants on hippocampal long-term potentiation in rats: an in vivo study. Brain research. vol 1539. 2014-06-20. PMID:24095795. |
the objective of this study was to determine the relation between the chronic consumption of a high-fat diet (hfd) and antioxidants on long-term potentiation (ltp) in dentate gyrus (dg) of the adult rat hippocampus in vivo. |
2014-06-20 |
2023-08-12 |
rat |
| Seyed Asaad Karimi, Iraj Salehi, Alireza Komaki, Abdolrahman Sarihi, Mohammad Zarei, Siamak Shahid. Effect of high-fat diet and antioxidants on hippocampal long-term potentiation in rats: an in vivo study. Brain research. vol 1539. 2014-06-20. PMID:24095795. |
it was suggested that chronic hfd consumption can impair hippocampal ltp in the granular cells of the dg, and antioxidant supplementation reverses the impairment of synaptic plasticity induced in dg. |
2014-06-20 |
2023-08-12 |
rat |
| Md Shahaduzzaman, Jason E Golden, Suzanne Green, Allisun E Gronda, Emanuelle Adrien, Aysha Ahmed, Paul R Sanberg, Paula C Bickford, Carmelina Gemma, Alison E Willin. A single administration of human umbilical cord blood T cells produces long-lasting effects in the aging hippocampus. Age (Dordrecht, Netherlands). vol 35. issue 6. 2014-06-19. PMID:23263793. |
human umbilical cord blood mononuclear cells (hucb mncs) have been shown to increase the proliferation of neural stem cells (nscs) in the dentate gyrus (dg) of the hippocampus and the subgranular zone of aging rats (bachstetter et al., bmc neurosci 9:22, 2008), but it is unclear which fraction or combination of the hucb mncs are responsible for neurogenesis. |
2014-06-19 |
2023-08-12 |
human |
| Geetha A Shetty, Bharathi Hattiangady, Ashok K Shett. Neural stem cell- and neurogenesis-related gene expression profiles in the young and aged dentate gyrus. Age (Dordrecht, Netherlands). vol 35. issue 6. 2014-06-19. PMID:23322452. |
thus, age-related decrease in hippocampal neurogenesis is not associated with a decline in the expression of selected genes important for nsc proliferation and neurogenesis in the dg. |
2014-06-19 |
2023-08-12 |
rat |
| N He, W-L Jin, K-H Lok, Y Wang, M Yin, Z-J Wan. Amyloid-β(1-42) oligomer accelerates senescence in adult hippocampal neural stem/progenitor cells via formylpeptide receptor 2. Cell death & disease. vol 4. 2014-06-12. PMID:24263098. |
loss of adult-born neurons and abnormalities of neural stem/progenitor cells (nspcs) within the dentate gyrus (dg) of adult hippocampus might contribute to this process. |
2014-06-12 |
2023-08-12 |
mouse |
| Justin A Cobb, Joy Simpson, Gouri J Mahajan, James C Overholser, George J Jurjus, Lesa Dieter, Nicole Herbst, Warren May, Grazyna Rajkowska, Craig A Stockmeie. Hippocampal volume and total cell numbers in major depressive disorder. Journal of psychiatric research. vol 47. issue 3. 2014-05-30. PMID:23201228. |
total volume of the hippocampal formation was calculated, and total numbers of pyramidal neurons (in hippocampal fields ca1, ca2/3, hilus), dentate gyrus (dg) granule cells, and glial cells were estimated stereologically. |
2014-05-30 |
2023-08-12 |
human |
| Rodrigo Herrera-Molina, Isabella Sarto-Jackson, Carolina Montenegro-Venegas, Martin Heine, Karl-Heinz Smalla, Constanze I Seidenbecher, Philip W Beesley, Eckart D Gundelfinger, Dirk Monta. Structure of excitatory synapses and GABAA receptor localization at inhibitory synapses are regulated by neuroplastin-65. The Journal of biological chemistry. vol 289. issue 13. 2014-05-21. PMID:24554721. |
here, we report that in the murine hippocampus and in hippocampal primary culture, neurons of the ca1 region and the dentate gyrus (dg) express high np65 levels, whereas expression in ca3 neurons is lower. |
2014-05-21 |
2023-08-12 |
mouse |
| Rodrigo Herrera-Molina, Isabella Sarto-Jackson, Carolina Montenegro-Venegas, Martin Heine, Karl-Heinz Smalla, Constanze I Seidenbecher, Philip W Beesley, Eckart D Gundelfinger, Dirk Monta. Structure of excitatory synapses and GABAA receptor localization at inhibitory synapses are regulated by neuroplastin-65. The Journal of biological chemistry. vol 289. issue 13. 2014-05-21. PMID:24554721. |
notably this picture is mirrored in mature np(-/-) hippocampal cultures or in mature ca1 and dg wild-type (np(+/+)) neurons treated with a function-blocking recombinant np65-fc extracellular fragment. |
2014-05-21 |
2023-08-12 |
mouse |
| Carmen Vivar, Henriette van Praa. Functional circuits of new neurons in the dentate gyrus. Frontiers in neural circuits. vol 7. 2014-05-19. PMID:23443839. |
new neurons are added throughout life to the hippocampal dentate gyrus (dg), a brain area considered important for differential storage of similar experiences and contexts. |
2014-05-19 |
2023-08-12 |
Not clear |
| Mariana Rodrigues Lopes, Luiz Eduardo Canton Santos, Antônio Márcio Rodrigues, Mario Antônio Duarte, Antonio Fernando Catelli Infantosi, Fulvio Alexandre Scorza, Ricardo Mario Arida, Ana Paula Madureira, Gilcélio Amaral da Silveira, Ivans Carlos dos Santos, Esper Abrão Cavalheiro, Antônio-Carlos Guimarães de Almeid. Effect of co-transporter blockers on non-synaptic epileptiform activity-computational simulation. Physical biology. vol 10. issue 5. 2014-05-16. PMID:24092000. |
the simulations were performed with an electrochemical model representing the non-synaptic structure of the granule cell layer of the dentate gyrus (dg) of the rat hippocampus. |
2014-05-16 |
2023-08-12 |
rat |
| J J Rodríguez, H N Noristani, T Hilditch, M Olabarria, C Y Yeh, J Witton, A Verkhratsk. Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease. Neuroscience letters. vol 552. 2014-05-15. PMID:23827221. |
as an integral part of the hippocampus, the dentate gyrus (dg) plays an important role in cognitive function. |
2014-05-15 |
2023-08-12 |
mouse |
| J J Rodríguez, H N Noristani, T Hilditch, M Olabarria, C Y Yeh, J Witton, A Verkhratsk. Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease. Neuroscience letters. vol 552. 2014-05-15. PMID:23827221. |
although post-mortem studies suggest later involvement of the dg into the ad progression, changes in microglia have not been studied in this subfield of the hippocampus. |
2014-05-15 |
2023-08-12 |
mouse |
| Xi Xu, Jianyun Zheng, Junfeng Zhang, Xinlin Chne, PengBo Yang, Jianxin Liu, Yong Li. [Neurogenesis in the dentate gyrus of the hippocampus in a rat model of intracerebral hemorrhage]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 33. issue 10. 2014-05-15. PMID:24144742. |
to investigate whether intracerebral hemorrhage (ich) can promote neurogenesis in the dentate gyrus (dg) of rat hippocampus. |
2014-05-15 |
2023-08-12 |
rat |
| Giorgio Aicard. Protein kinase Mζ-dependent maintenance of GluA2 at the synapse: a possible target for preventing or treating age-related memory decline? Rejuvenation research. vol 16. issue 4. 2014-05-05. PMID:23679685. |
age-related functional alterations in the perforant path projection from the entorhinal cortex to the dentate gyrus (dg) of the hippocampus play a major role in age-related memory impairments, but little is known about the molecular mechanisms responsible for these changes. |
2014-05-05 |
2023-08-12 |
monkey |
| Giorgio Aicard. Protein kinase Mζ-dependent maintenance of GluA2 at the synapse: a possible target for preventing or treating age-related memory decline? Rejuvenation research. vol 16. issue 4. 2014-05-05. PMID:23679685. |
then they performed electron microscopy immunocytochemistry in the hippocampal dg to determine the subcellular localization of the glua2 subunit of the glutamate α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor (ampar) and protein kinase mζ (pkmζ), which promotes memory storage by regulating glua2-containing ampar trafficking. |
2014-05-05 |
2023-08-12 |
monkey |
| Kyunghee Byun, Daesik Kim, Enkhjaigal Bayarsaikhan, Jeehyun Oh, Jisun Kim, Grace Kwak, Goo-Bo Jeong, Seung-Mook Jo, Bonghee Le. Changes of calcium binding proteins, c-Fos and COX in hippocampal formation and cerebellum of Niemann-Pick, type C mouse. Journal of chemical neuroanatomy. vol 52. 2014-05-02. PMID:23660496. |
parvalbumin, cox-1,2 or c-fos-immunoreactive neurons were widely detected in the ca1, ca3, and dg of the hippocampus, but the immunoreactivities were decreased sharply in all areas of hippocampus of npc-/- compared to npc+/+ and npc+/- mice. |
2014-05-02 |
2023-08-12 |
mouse |