Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Roger L Redondo, Joshua Kim, Autumn L Arons, Steve Ramirez, Xu Liu, Susumu Tonegaw. Bidirectional switch of the valence associated with a hippocampal contextual memory engram. Nature. vol 513. issue 7518. 2014-10-14. PMID:25162525. |
we labelled with channelrhodopsin-2 (chr2) a population of cells in either the dorsal dentate gyrus (dg) of the hippocampus or the basolateral complex of the amygdala (bla) that were specifically activated during contextual fear or reward conditioning. |
2014-10-14 |
2023-08-13 |
mouse |
Yan-You Huang, Amir Levine, Denise B Kandel, Deqi Yin, Luca Colnaghi, Bettina Drisaldi, Eric R Kande. D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 3. 2014-10-12. PMID:24549570. |
the dentate gyrus (dg) of the hippocampus is critical for spatial memory and is also thought to be involved in the formation of drug-related associative memory. |
2014-10-12 |
2023-08-12 |
mouse |
Yan-You Huang, Amir Levine, Denise B Kandel, Deqi Yin, Luca Colnaghi, Bettina Drisaldi, Eric R Kande. D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 3. 2014-10-12. PMID:24549570. |
these results demonstrate that the dg of the hippocampus is an important brain region contributing to the priming effect of nicotine on cocaine. |
2014-10-12 |
2023-08-12 |
mouse |
Birsen Elibol-Can, Ertugrul Kilic, Sinan Yuruker, Ewa Jakubowska-Dogr. Investigation into the effects of prenatal alcohol exposure on postnatal spine development and expression of synaptophysin and PSD95 in rat hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 33. 2014-10-10. PMID:24365761. |
the spine densities as well as the expression of pre- and postsynaptic proteins, synaptophysin (syp) and psd-95 protein, were evaluated for three distinct hippocampal regions: ca1, ca2+3, and dg and four postnatal days: pd1, pd10, pd30 and pd60, independently. |
2014-10-10 |
2023-08-12 |
human |
Takayuki Nakajima, Masafumi Yanagihara, Hideki Nishi. Temporal and regional patterns of Smad activation in the rat hippocampus following global ischemia. Journal of the neurological sciences. vol 337. issue 1-2. 2014-10-06. PMID:24290497. |
we found that 1) smad1, -2, -3, and -5 proteins were detected in the rat hippocampus by means of western blot and immunohistochemistry; 2) after 5 min of ischemia, smad2 and smad3 proteins accumulated in the nuclei of pyramidal cells in the ca1 region, which is vulnerable to ischemia; 3) after 3 min of ischemia, which was non-lethal, there was no such nuclear accumulation of smad2 and smad3 in the ca1 region; 4) following injection of activin a, nuclear accumulation of smad2 and smad3 was induced not only in pyramidal cells of the ca1 region, but also in pyramidal cells of the ca3 region as well as in granule cells of the dg region; 5) activin a-induced nuclear accumulation of smad2 and smad3 neither caused degeneration of hippocampal neurons nor prevented degeneration induced by ischemia. |
2014-10-06 |
2023-08-12 |
rat |
Adi Shruster, Daniel Offe. Targeting neurogenesis ameliorates danger assessment in a mouse model of Alzheimer's disease. Behavioural brain research. vol 261. 2014-10-06. PMID:24388979. |
we report that in the 3xtgad mouse model of ad, chronic wnt3a overexpression in the ventral hippocampus dentate gyrus (dg) restored adult neurogenesis to physiological levels. |
2014-10-06 |
2023-08-12 |
mouse |
Adi Shruster, Daniel Offe. Targeting neurogenesis ameliorates danger assessment in a mouse model of Alzheimer's disease. Behavioural brain research. vol 261. 2014-10-06. PMID:24388979. |
finally, using a bed nucleus of stria terminalis (bnst) mrna expression array, we found that the expression of the 5-ht1a receptor in 3xtgad mice is selectively decreased and normalized by wnt3a overexpression in the ventral hippocampus dg, and this normalization is neurogenesis dependent. |
2014-10-06 |
2023-08-12 |
mouse |
Miwako Kobayashi, Toshiyuki Nakatani, Toshiaki Koda, Ken-Ichi Matsumoto, Ryosuke Ozaki, Natsuki Mochida, Keizo Takao, Tsuyoshi Miyakawa, Ichiro Matsuok. Absence of BRINP1 in mice causes increase of hippocampal neurogenesis and behavioral alterations relevant to human psychiatric disorders. Molecular brain. vol 7. 2014-09-29. PMID:24528488. |
of the three family members, brinp1 is the most highly expressed in various brain regions, including the hippocampus, in adult mice and its expression in dentate gyrus (dg) is markedly induced by neural activity. |
2014-09-29 |
2023-08-12 |
mouse |
S G Travis, Y Huang, E Fujiwara, A Radomski, F Olsen, R Carter, P Seres, N V Malykhi. High field structural MRI reveals specific episodic memory correlates in the subfields of the hippocampus. Neuropsychologia. vol 53. 2014-09-24. PMID:24296251. |
the hc subfields - the cornu ammonis 1-3 (ca), dentate gyrus (dg), and subiculum (sub) - were segmented manually within three hippocampal subregions using a previously defined protocol. |
2014-09-24 |
2023-08-12 |
human |
M L Choi, F Begeti, J H Oh, S Y Lee, G C O'Keeffe, C D Clelland, P Tyers, Z H Cho, Y B Kim, R A Barke. Dopaminergic manipulations and its effects on neurogenesis and motor function in a transgenic mouse model of Huntington's disease. Neurobiology of disease. vol 66. 2014-09-24. PMID:24561069. |
we showed that there was an early reduction of d2r in both the striatum and dentate gyrus (dg) of the hippocampus in the r6/1 transgenic hd mouse ahead of any overt motor signs and before striatal neuronal loss. |
2014-09-24 |
2023-08-12 |
mouse |
Takeshi Fujii, Daisuke N Saito, Hisakazu T Yanaka, Hirotaka Kosaka, Hidehiko Okazaw. Depressive mood modulates the anterior lateral CA1 and DG/CA3 during a pattern separation task in cognitively intact individuals: a functional MRI study. Hippocampus. vol 24. issue 2. 2014-09-23. PMID:24123715. |
although patients with major depressive disorder typically have a reduced hippocampal volume, particularly in the cornu ammonis 1 (ca1), animal studies suggest that depressive mood is related to the dentate gyrus (dg). |
2014-09-23 |
2023-08-12 |
human |
Brisa M M Monteiro, Fabrício A Moreira, André R Massensini, Márcio F D Moraes, Grace S Pereir. Enriched environment increases neurogenesis and improves social memory persistence in socially isolated adult mice. Hippocampus. vol 24. issue 2. 2014-09-23. PMID:24123782. |
we observed an increase in the number of newborn neurons in the dentate gyrus of the hippocampus (dg) and glomerular layer of the olfactory bulb (ob) in both gh+ee and si+ee mice. |
2014-09-23 |
2023-08-12 |
mouse |
Mika Onishi, Mitsuo Iinuma, Yasuo Tamura, Kin-Ya Kub. Learning deficits and suppression of the cell proliferation in the hippocampal dentate gyrus of offspring are attenuated by maternal chewing during prenatal stress. Neuroscience letters. vol 560. 2014-09-08. PMID:24355359. |
prenatal stress in dams induces learning deficits and suppresses neurogenesis in the hippocampal dentate gyrus (dg) of offspring via increasing corticosterone levels in the dam. |
2014-09-08 |
2023-08-12 |
mouse |
Mika Onishi, Mitsuo Iinuma, Yasuo Tamura, Kin-Ya Kub. Learning deficits and suppression of the cell proliferation in the hippocampal dentate gyrus of offspring are attenuated by maternal chewing during prenatal stress. Neuroscience letters. vol 560. 2014-09-08. PMID:24355359. |
here, we examined whether chewing during prenatal stress prevents the stress-induced learning deficits and the suppression of cell proliferation in the hippocampal dg in adult offspring. |
2014-09-08 |
2023-08-12 |
mouse |
Mika Onishi, Mitsuo Iinuma, Yasuo Tamura, Kin-Ya Kub. Learning deficits and suppression of the cell proliferation in the hippocampal dentate gyrus of offspring are attenuated by maternal chewing during prenatal stress. Neuroscience letters. vol 560. 2014-09-08. PMID:24355359. |
the pups were raised to adulthood, and learning ability and cell proliferation in the hippocampal dg were assessed. |
2014-09-08 |
2023-08-12 |
mouse |
Graham K Sheridan, Anita Wdowicz, Mark Pickering, Orla Watters, Paul Halley, Niamh C O'Sullivan, Claire Mooney, David J O'Connell, John J O'Connor, Keith J Murph. CX3CL1 is up-regulated in the rat hippocampus during memory-associated synaptic plasticity. Frontiers in cellular neuroscience. vol 8. 2014-08-27. PMID:25161610. |
we report an up-regulation in cx3cl1 protein expression in the ca1, ca3 and dentate gyrus (dg) of the rat hippocampus 2 h after spatial learning in the water maze task. |
2014-08-27 |
2023-08-13 |
rat |
Shinya Ohara, Sho Sato, Ken-Ichiro Tsutsui, Menno P Witter, Toshio Iijim. Organization of multisynaptic inputs to the dorsal and ventral dentate gyrus: retrograde trans-synaptic tracing with rabies virus vector in the rat. PloS one. vol 8. issue 11. 2014-08-26. PMID:24223172. |
this second-order input difference in the dorsal and ventral dg is likely to contribute to the functional differentiation of the hippocampus along the dorsoventral axis. |
2014-08-26 |
2023-08-12 |
rat |
Sun Shin Y. Time-dependent changes of calbindin D-28K and parvalbumin immunoreactivity in the hippocampus of rats with streptozotocin-induced type 1 diabetes. Journal of veterinary science. vol 14. issue 4. 2014-08-21. PMID:23628656. |
in contrast, the number of pv-immunoreactive neurons and fibers was unchanged in the hippocampus and dg 2 weeks after stz treatment. |
2014-08-21 |
2023-08-12 |
rat |
Joshua Sariñana, Takashi Kitamura, Patrik Künzler, Lisa Sultzman, Susumu Tonegaw. Differential roles of the dopamine 1-class receptors, D1R and D5R, in hippocampal dependent memory. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 22. 2014-08-20. PMID:24843151. |
generation of d1r- and d5r-specific in situ hybridization probes showed that d1r and d5r mrna expression was greatest in the dentate gyrus (dg) of the hippocampus. |
2014-08-20 |
2023-08-13 |
mouse |
Jun Yang, Ming-Xing Li, Yi Luo, Tao Chen, Jing Liu, Peng Fang, Bo Jiang, Zhuang-Li Hu, You Jin, Jian-Guo Chen, Fang Wan. Chronic ceftriaxone treatment rescues hippocampal memory deficit in AQP4 knockout mice via activation of GLT-1. Neuropharmacology. vol 75. 2014-08-19. PMID:23973312. |
besides its important role in water transport across the blood-brain barrier, our present study demonstrated that aqp4 deficiency impaired hippocampal long-term potentiation (ltp) and hippocampus-dependent memory formation, accompanied by the increase in extracellular glutamate concentration and n-methyl-d-aspartate (nmda) receptor-mediated currents in hippocampal dentate gyrus (dg) region. |
2014-08-19 |
2023-08-12 |
mouse |