Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
C Lannér, Y Suzuki, C Bi, H Zhang, L D Cooper, M M Bowker-Kinley, A A DePaoli-Roac. Gene structure and expression of the targeting subunit, RGL, of the muscle-specific glycogen-associated type 1 protein phosphatase, PP1G. Archives of biochemistry and biophysics. vol 388. issue 1. 2001-06-14. PMID:11361130. |
analysis of skeletal muscle from rats made diabetic by streptozotocin treatment reveals that the level of r(gl) protein is the same as in control animals, indicating that expression is not regulated by insulin. |
2001-06-14 |
2023-08-12 |
mouse |
L Köhidai, N Schiess, G Csab. Chemotactic selection of Tetrahymena pyriformis GL induced with histamine, di-iodotyrosine or insulin. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 126. issue 1. 2000-12-28. PMID:11048659. |
chemotactic selection of tetrahymena pyriformis gl induced with histamine, di-iodotyrosine or insulin. |
2000-12-28 |
2023-08-12 |
human |
M J Doherty, J Cadefau, W Stalmans, M Bollen, P T Cohe. Loss of the hepatic glycogen-binding subunit (GL) of protein phosphatase 1 underlies deficient glycogen synthesis in insulin-dependent diabetic rats and in adrenalectomized starved rats. The Biochemical journal. vol 333 ( Pt 2). 1998-09-10. PMID:9657963. |
insulin administration to diabetic rats restored the level of gl and prolonged administration raised it above the control levels, whereas re-feeding partially restored the gl level in adrenalectomized starved rats. |
1998-09-10 |
2023-08-12 |
rat |
M J Doherty, J Cadefau, W Stalmans, M Bollen, P T Cohe. Loss of the hepatic glycogen-binding subunit (GL) of protein phosphatase 1 underlies deficient glycogen synthesis in insulin-dependent diabetic rats and in adrenalectomized starved rats. The Biochemical journal. vol 333 ( Pt 2). 1998-09-10. PMID:9657963. |
the regulation of gl protein levels by insulin and starvation/feeding was shown to correlate with changes in the level of the gl mrna, indicating that the long-term regulation of the hepatic glycogen-associated form of pp1 by insulin, and hence the activity of hepatic glycogen synthase, is predominantly mediated through changes in the level of the gl mrna. |
1998-09-10 |
2023-08-12 |
rat |
B H Goodpaster, D L Costill, W J Fink, T A Trappe, A C Jozsi, R D Starling, S W Trapp. The effects of pre-exercise starch ingestion on endurance performance. International journal of sports medicine. vol 17. issue 5. 1997-01-13. PMID:8858409. |
thirty min prior to exercise, they ingested 1 g.kg-1 body weight of gl, ws, rs, or pl at rest, gl elicited greater (p < 0.05) serum glucose and insulin responses than all other trials. |
1997-01-13 |
2023-08-12 |
human |
M Todaka, H Hayashi, T Imanaka, Y Mitani, S Kamohara, K Kishi, K Tamaoka, F Kanai, M Shichiri, N Morii, S Narumiya, Y Ebin. Roles of insulin, guanosine 5'-[gamma-thio]triphosphate and phorbol 12-myristate 13-acetate in signalling pathways of GLUT4 translocation. The Biochemical journal. vol 315 ( Pt 3). 1996-07-15. PMID:8645171. |
insulin, guanosine 5'-[gamma-thio]triphosphate (gtp[s] and phorbol 12-myristate 13-acetate (pma) trigger the translocation of gl ut4 (type 4 glucose transporter; insulin-sensitive glucose transporter) from an intracellular pool to the cell surface. |
1996-07-15 |
2023-08-12 |
Not clear |
A Della Rossa, R Putt. The endocrine pancreas of lacertids: an immunocytochemical study of the genera Pedioplanis and Meroles. European journal of histochemistry : EJH. vol 39. issue 1. 1995-08-18. PMID:7542043. |
the endocrine pancreas from 2 genera of lacertid lizards (pedioplanis and meroles) was investigated immunocytochemically for the presence of immunoreactivity to mammalian antisera to insulin (i), glucagon (g), pancreatic polypeptide (pp), peptide tyrosine tyrosine (pyy), neuropeptide tyrosine (npy), somatostatin 14 (srif 14) and somatostatin 28 (srif 28), pancreastatin (pst), galanin (gl), oxytocin (ot). |
1995-08-18 |
2023-08-12 |
Not clear |
L Macho, M Ficková, S Zorad, J Knop. Changes of insulin and glucagon binding to receptors in hepatocytes during liver regeneration. Physiological research. vol 43. issue 5. 1995-05-18. PMID:7711005. |
the binding of insulin (ins) and glucagon (gl) on isolated rat hepatocytes during the process of liver regeneration after partial hepatectomy was determined. |
1995-05-18 |
2023-08-12 |
rat |
A Pugliese, T Bugawan, R Moromisato, Z L Awdeh, C A Alper, R A Jackson, H A Erlich, G S Eisenbart. Two subsets of HLA-DQA1 alleles mark phenotypic variation in levels of insulin autoantibodies in first degree relatives at risk for insulin-dependent diabetes. The Journal of clinical investigation. vol 93. issue 6. 1994-07-07. PMID:8200980. |
homozygosity for gl alleles (often dqa1 *0501 on dr3 haplotypes) correlated with little or no humoral response to insulin. |
1994-07-07 |
2023-08-12 |
Not clear |
A Pugliese, T Bugawan, R Moromisato, Z L Awdeh, C A Alper, R A Jackson, H A Erlich, G S Eisenbart. Two subsets of HLA-DQA1 alleles mark phenotypic variation in levels of insulin autoantibodies in first degree relatives at risk for insulin-dependent diabetes. The Journal of clinical investigation. vol 93. issue 6. 1994-07-07. PMID:8200980. |
thus, hla-dqb1 gl alleles, or other genes on haplotypes (e.g., dr3) that carry these dqa1 alleles, may confer recessive low responsiveness to insulin. |
1994-07-07 |
2023-08-12 |
Not clear |
B A Zinker, D B Lacy, D P Bracy, D H Wasserma. Role of glucose and insulin loads to the exercising limb in increasing glucose uptake and metabolism. Journal of applied physiology (Bethesda, Md. : 1985). vol 74. issue 6. 1993-10-01. PMID:8365992. |
to assess the contributions of glucose load to the working hindlimb and local contraction-related events (changes related to the microvasculature and/or intrinsic muscle metabolic properties) to the exercise-induced increases in muscle glucose uptake and metabolism in vivo, dogs were studied with somatostatin infused to suppress insulin release, and glucose and insulin were replaced 1) during rest and treadmill exercise at rates that recreate limb glucose and insulin loads evident during exercise (n = 5), 2) at rest to selectively normalize the limb glucose load to rates present during exercise while retaining basal limb insulin loads (gl, n = 5), or 3) at rest to normalize both the limb glucose and insulin loads to those present during exercise (igl, n = 5). |
1993-10-01 |
2023-08-12 |
Not clear |
B A Zinker, D B Lacy, D P Bracy, D H Wasserma. Role of glucose and insulin loads to the exercising limb in increasing glucose uptake and metabolism. Journal of applied physiology (Bethesda, Md. : 1985). vol 74. issue 6. 1993-10-01. PMID:8365992. |
limb insulin loads were similar to basal loads in gl (8.8 +/- 1.9 nmol/min) and exercise in igl (28.2 +/- 5.5 nmol/min). |
1993-10-01 |
2023-08-12 |
Not clear |
L Niskanen, J Lahti, M Uusitup. Morning or bed-time insulin with or without glibenclamide in elderly type 2 diabetic patients unresponsive to oral antidiabetic agents. Diabetes research and clinical practice. vol 18. issue 3. 1993-03-22. PMID:1289019. |
a further improvement in metabolic control was observed in both groups after the introduction of gl; the mean reduction in glycosylated hba1c was 1.4% for bti and 0.7% for mi (p < 0.01 and 0.05, respectively), in conclusion, a subgroup of poorly controlled elderly type 2 diabetic patients showed an improvement in metabolic control after a single injection of insulin despite discontinuation of maximal doses of oral antidiabetic agents. |
1993-03-22 |
2023-08-11 |
human |
P Kovács, G Csab. Evidence of the receptor nature of the binding sites induced in Tetrahymena by insulin treatment. A quantitative cytofluorimetric technique for the study of binding kinetics. Cell biochemistry and function. vol 8. issue 1. 1990-06-28. PMID:2111234. |
tetrahymena pyriformis gl cells pretreated (imprinted) and not pretreated with insulin showed dissimilar quantitative relations of fitc-insulin binding. |
1990-06-28 |
2023-08-11 |
Not clear |
D A Humberstone, J Koea, J H Sha. Relative importance of amino acid infusion as a means of sparing protein in surgical patients. JPEN. Journal of parenteral and enteral nutrition. vol 13. issue 3. 1989-09-15. PMID:2503631. |
(3) this effect is not solely due to insulin secretion as larger insulin responses were seen with both gl and tpn patients. |
1989-09-15 |
2023-08-11 |
Not clear |
C Benelli, S Lopez, B Desbuquois, C Achagioti. Changes in low-Km cAMP phosphodiesterase activity in liver Golgi fractions from hyper- and hypoinsulinemic rats. Diabetes. vol 37. issue 6. 1988-08-04. PMID:2838352. |
infusion of insulin through chronically implanted intracardiac catheters led to a 30-50% increase in golgi-associated camp pde, which occurred earlier in gi (3 h) than in gh (7 h) and persisted for greater than 96 h. injection of anti-insulin serum led to a 30-50% decrease in golgi-associated camp pde, which occurred sequentially in gl (5 min), gi (15 min), and gh (30 min) and affected predominantly gl and gh. |
1988-08-04 |
2023-08-11 |
rat |
A M del Pozo, Y Valladares, Y Alvarez Rodrígue. [Energy metabolism of Ehrlich ascites cancer cells]. Revista espanola de oncologia. vol 30. issue 4. 1988-02-10. PMID:6400622. |
insulin produces a lowering of cr to 26, aerobic gl to 26 and anaerobic gl to 22. |
1988-02-10 |
2023-08-12 |
Not clear |
L Köhidai, G Csab. Effects of insulin and histamine in themselves and in combination on the glucose metabolism of Tetrahymena. Acta biologica Hungarica. vol 36. issue 3-4. 1987-05-06. PMID:2951951. |
the glucose metabolism and the related intracellular processes of tetrahymena pyriformis gl cells are measurably influenced by several hormones of higher organisms, among others by the endocytosis stimulating hormone histamine, and the glucose metabolism regulating hormone insulin. |
1987-05-06 |
2023-08-11 |
Not clear |
L Köhidai, G Csab. Effects of insulin and histamine in themselves and in combination on the glucose metabolism of Tetrahymena. Acta biologica Hungarica. vol 36. issue 3-4. 1987-05-06. PMID:2951951. |
histamine does not interfere with the glucose metabolizing action of insulin, but markedly enhances the utilization of glucose, to judge from a significant decrease in the pas-positive (hexose) component of histamine-exposed tetrahymena pyriformis gl cells. |
1987-05-06 |
2023-08-11 |
Not clear |
R A Sobel, R B Colvi. Responder strain-specific enhancement of endothelial and mononuclear cell Ia in delayed hypersensitivity reactions in (strain 2 X strain 13)F1 guinea pigs. Journal of immunology (Baltimore, Md. : 1950). vol 137. issue 7. 1986-10-30. PMID:3531327. |
seven adult (strain 2 x strain 13)f1 and two strain 13 guinea pigs were sensitized with poly-l glutamic acid-lysine (gl), poly-l glutamic acid-tyrosine (gt), and bovine insulin in complete freund's adjuvant, and were skin tested with gl, gt, ppd, bovine insulin, porcine insulin (which has the same b chain as bovine insulin), and saline. |
1986-10-30 |
2023-08-11 |
cattle |