| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Morimoto, G V Goddar. The substantia nigra is an important site for the containment of seizure generalization in the kindling model of epilepsy. Epilepsia. vol 28. issue 1. 1987-02-19. PMID:3792287. |
to investigate the role of the substantia nigra (sn) in kindling, electrical stimulation of the sn was delivered at various times before or after stimulation of the amygdala (am) or pyriform cortex during or after kindling in rats. |
1987-02-19 |
2023-08-11 |
rat |
| J D Elsworth, A Y Deutch, D E Redmond, J R Sladek, R H Rot. Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum. Life sciences. vol 40. issue 2. 1987-02-11. PMID:3491946. |
however, the asymptomatic animals had normal da concentration in the substantia nigra (sn); yet in the symptomatic animal da was largely depleted in the central (86%) and medial (94%), but not lateral (8%) regions of the sn. |
1987-02-11 |
2023-08-11 |
monkey |
| A Morimoto, T Nakamori, T Ono, T Watanabe, Y Sakai, N Murakam. Changes in [14C]deoxyglucose incorporation into rat brain regions during heat-seeking behavior in the cold environment. Physiology & behavior. vol 38. issue 2. 1987-02-10. PMID:3797493. |
when animals were only exposed to cold, significant increases in [14c]-dg incorporation were observed in the caudate putamen, lateral preoptic area, medial forebrain bundle, ventromedial hypothalamus (vmh), posterior hypothalamus, ventroposteromedial thalamus (vpm), dorsomedial thalamus (md), substantia nigra (sn) and red nucleus (rn). |
1987-02-10 |
2023-08-11 |
rat |
| R Barke. Substance P and Parkinson's disease: a causal relationship? Journal of theoretical biology. vol 120. issue 3. 1987-01-22. PMID:2431225. |
here i present evidence to show that pd may result from a primary loss of active tachykinin, probably substance p (sp) in the substantia nigra (sn), and that this loss leads to a secondary degeneration of the dopaminergic neurones. |
1987-01-22 |
2023-08-11 |
Not clear |
| T N Ferraro, G T Golden, M DeMattei, T A Hare, R G Fariell. Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on levels of glutathione in the extrapyramidal system of the mouse. Neuropharmacology. vol 25. issue 9. 1986-12-12. PMID:2430229. |
depletion of striatal dopamine and metabolites in mptp-treated mice is accompanied by depletion of glutathione (gsh) in the substantia nigra (sn). |
1986-12-12 |
2023-08-11 |
mouse |
| V Leviel, B Charriere, C Fayada, B Guiber. Nigroamygdaloid dopamine neurons: nigral modulation of their activity. Brain research. vol 381. issue 2. 1986-11-20. PMID:3019477. |
halothane anesthetized rats were implanted, according to the experiment, with one or two push-pull cannulae in the central nuclei of the amygdala (ace), the substantia nigra (sn) and/or the caudate nucleus (cn). |
1986-11-20 |
2023-08-11 |
rat |
| D W Bonhaus, J R Walters, J O McNamar. Activation of substantia nigra neurons: role in the propagation of seizures in kindled rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 6. issue 10. 1986-11-12. PMID:3760946. |
the substantia nigra (sn) is crucial to the propagation of seizures in kindled rats and in other experimental seizure models. |
1986-11-12 |
2023-08-11 |
rat |
| G Crescimanno, P Piazza, A Benigno, G Amat. Effects of substantia nigra stimulation on hypothalamic rage reaction in cats. Physiology & behavior. vol 37. issue 1. 1986-09-17. PMID:3737710. |
the effects of substantia nigra (sn) (pars compacta) stimulation on the rage reaction elicited by ventromedial hypothalamic nucleus (vmh) were investigated in the cat. |
1986-09-17 |
2023-08-11 |
cat |
| R Thompson, R B Gibbs, G A Ristic, C W Cotman, J Y. Learning deficits in rats with early neurotoxic lesions to the globus pallidus, substantia nigra, median raphe or pontine reticular formation. Physiology & behavior. vol 37. issue 1. 1986-09-17. PMID:3737712. |
previous studies have shown that weanling rats with electrolytic lesions of the globus pallidus (gp), substantia nigra (sn), median raphe (mr) or pontine reticular formation (prf) are deficient in learning a wide variety of laboratory tasks. |
1986-09-17 |
2023-08-11 |
rat |
| D Garant, K Gal. Intranigral muscimol attenuates electrographic signs of seizure activity induced by intravenous bicuculline in rats. European journal of pharmacology. vol 124. issue 3. 1986-09-16. PMID:3732385. |
rats were implanted with infusion cannulas in the substantia nigra (sn), and intracranial electrodes for recording the electroencephalogram (eeg). |
1986-09-16 |
2023-08-11 |
rat |
| A J Bradbury, B Costall, A M Domeney, P J Jenner, C D Marsden, R J Naylo. The neurotoxic actions of 6-hydroxydopamine infused into the rat substantia nigra. Neuroscience letters. vol 67. issue 2. 1986-08-15. PMID:2425303. |
6-hydroxydopamine (6-ohda) 10 and 40 micrograms/24 h infused bilaterally for 4 days into the rat substantia nigra (sn) caused a 'freezing' akinetic response which was apparent within 24 h and which persisted throughout the period of infusion. |
1986-08-15 |
2023-08-11 |
rat |
| B J Albala, S L Moshé, J F Cubells, N S Sharpless, M H Makma. Unilateral peri-substantia nigra catecholaminergic lesion and amygdala kindling. Brain research. vol 370. issue 2. 1986-06-27. PMID:3085869. |
recent evidence suggests that the substantia nigra (sn) may be involved in the modulation of kindled seizures in adult rats. |
1986-06-27 |
2023-08-11 |
rat |
| Y Ohno, M Sasa, S Takaor. Excitation by dopamine D-2 receptor agonists, bromocriptine and LY 171555, in caudate nucleus neurons activated by nigral stimulation. Life sciences. vol 38. issue 20. 1986-06-25. PMID:2939313. |
electrophysiological studies using cats anesthetized with alpha-chloralose were carried out to determine whether or not the dopamine d-2 receptor mediates the excitation of the caudate nucleus (cn) neurons activated by stimulation of the substantia nigra (sn). |
1986-06-25 |
2023-08-11 |
Not clear |
| G Mittleman, E S Valenstei. Unilateral substantia nigra lesions and schedule-induced polydipsia. Physiology & behavior. vol 36. issue 3. 1986-06-11. PMID:3085114. |
the present experiment investigated the effects of unilateral 6-hydroxydopamine lesions of the substantia nigra (sn) on schedule-induced polydipsia (sip). |
1986-06-11 |
2023-08-11 |
Not clear |
| M Buonamici, R Maj, F Pagani, A C Rossi, N Khaza. Tremor at rest episodes in unilaterally 6-OHDA-induced substantia nigra lesioned rats: EEG-EMG and behavior. Neuropharmacology. vol 25. issue 3. 1986-06-06. PMID:3084991. |
twenty male adult wistar rats were unilaterally lesioned in the substantia nigra (sn) with 6-hydroxydopamine (6-ohda), and prepared with chronic cortical (ecog) and neck muscle (emg) electrodes. |
1986-06-06 |
2023-08-11 |
rat |
| J O McNamar. Kindling model of epilepsy. Advances in neurology. vol 44. 1986-05-30. PMID:2871721. |
recent investigations directly related to the network issue are considered, namely studies demonstrating that a brainstem structure, the substantia nigra (sn), can regulate the kindled seizure threshold. |
1986-05-30 |
2023-08-11 |
human |
| K Gal. Role of the substantia nigra in GABA-mediated anticonvulsant actions. Advances in neurology. vol 44. 1986-05-30. PMID:3010676. |
the substantia nigra (sn) has been identified as a critical site at which gaba-agonist drugs act to reduce susceptibility to a number of types of experimentally induced generalized seizures. |
1986-05-30 |
2023-08-11 |
human |
| R W Olsen, J K Wamsley, R J Lee, P Loma. Benzodiazepine/barbiturate/GABA receptor-chloride ionophore complex in a genetic model for generalized epilepsy. Advances in neurology. vol 44. 1986-05-30. PMID:3010677. |
this was shown by quantitative brain-slice binding autoradiography to involve a decrease in the number of binding sites in the substantia nigra (sn) and periaqueductal gray regions. |
1986-05-30 |
2023-08-11 |
human |
| K Kao, D A Powel. Lesions of substantia nigra retard pavlovian somatomotor learning but do not affect autonomic conditioning. Neuroscience letters. vol 64. issue 1. 1986-05-07. PMID:3960383. |
new zealand albino rabbits with bilateral radio frequency lesions of the substantia nigra (sn) were compared with sham-operated animals on a pavlovian conditioning task in which eyeblink (eb) and heart rate (hr) responses were concomitantly assessed. |
1986-05-07 |
2023-08-11 |
Not clear |
| M S Cannon, E D Kapes, M E Trulso. A histochemical examination of the metabolic profiles of rat ventral tegmental area and substantia nigra arterioles. Neuroscience letters. vol 64. issue 1. 1986-05-07. PMID:3960393. |
to determine the metabolic profiles of arterioles of the rat ventral tegmental area and zona compacta and zona reticulata of the substantia nigra (sn), the distribution of selected enzymes, or by-products, of key metabolic pathways were examined histologically. |
1986-05-07 |
2023-08-11 |
rat |