| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E D Levin, B B Simo. Nicotinic acetylcholine involvement in cognitive function in animals. Psychopharmacology. vol 138. issue 3-4. 1998-11-04. PMID:9725745. |
the hippocampus, frontal cortex and midbrain dopaminergic nuclei have been found to be important sites of action for nicotinic involvement in memory function. |
1998-11-04 |
2023-08-12 |
human |
| S Benisty, F Boissiere, B Faucheux, Y Agid, E C Hirsc. trkB messenger RNA expression in normal human brain and in the substantia nigra of parkinsonian patients: an in situ hybridization study. Neuroscience. vol 86. issue 3. 1998-10-29. PMID:9692719. |
furthermore, we compared trkb messenger rna expression in the mesencephalon of six control subjects and five patients with parkinson's disease, a neurodegenerative disorder characterized by a severe loss of dopaminergic neurons. |
1998-10-29 |
2023-08-12 |
human |
| J Engel. Spatial and temporal growth factor influences on developing midbrain dopaminergic neurons. Journal of neuroscience research. vol 53. issue 4. 1998-10-28. PMID:9710260. |
spatial and temporal growth factor influences on developing midbrain dopaminergic neurons. |
1998-10-28 |
2023-08-12 |
rat |
| J Engel. Spatial and temporal growth factor influences on developing midbrain dopaminergic neurons. Journal of neuroscience research. vol 53. issue 4. 1998-10-28. PMID:9710260. |
to address this issue, glia and neurons of both the mesencephalic home region as well as the striatal and cortical target areas have been screened for effects on dopaminergic cell survival in serum-free dissociated cell cultures of the embryonic day (e) 15 and e17 rat mesencephalon. |
1998-10-28 |
2023-08-12 |
rat |
| J Engel. Spatial and temporal growth factor influences on developing midbrain dopaminergic neurons. Journal of neuroscience research. vol 53. issue 4. 1998-10-28. PMID:9710260. |
in e15 mesencephalic cultures, the number of surviving tyrosine hydroxylase-immunoreactive dopaminergic neurons maximally increased 2.6-fold with medium conditioned by glia of the e15-e20 mesencephalon, the e17-e20 striatum, or the e20 cortex. |
1998-10-28 |
2023-08-12 |
rat |
| M Crispino, G Tocco, J D Feldman, H R Herschman, M Baudr. Nurr1 mRNA expression in neonatal and adult rat brain following kainic acid-induced seizure activity. Brain research. Molecular brain research. vol 59. issue 2. 1998-10-28. PMID:9729370. |
nurr1 is predominantly expressed in the brain, and is essential to the differentiation of midbrain dopaminergic neurons. |
1998-10-28 |
2023-08-12 |
rat |
| M Ghee, H Baker, J C Miller, E B Zif. AP-1, CREB and CBP transcription factors differentially regulate the tyrosine hydroxylase gene. Brain research. Molecular brain research. vol 55. issue 1. 1998-10-09. PMID:9645965. |
immunohistochemical studies in rat brain regions enriched in dopaminergic neurons, including the midbrain and olfactory bulb (ob), suggest that fos-jun and creb make differential contributions to th gene activity in different tissues. |
1998-10-09 |
2023-08-12 |
rat |
| M Ghee, H Baker, J C Miller, E B Zif. AP-1, CREB and CBP transcription factors differentially regulate the tyrosine hydroxylase gene. Brain research. Molecular brain research. vol 55. issue 1. 1998-10-09. PMID:9645965. |
in contrast, the presence of creb and the absence of fos immunoreactivity in midbrain dopaminergic cells suggests that the cre is the primary regulator in this region. |
1998-10-09 |
2023-08-12 |
rat |
| C Beyer, H Raa. Nongenomic effects of oestrogen: embryonic mouse midbrain neurones respond with a rapid release of calcium from intracellular stores. The European journal of neuroscience. vol 10. issue 1. 1998-10-08. PMID:9753134. |
oestrogens have been shown to modulate the differentiation and function of embryonic midbrain dopaminergic neurones by stimulating neurite outgrowth, expression of tyrosine hydroxylase mrna, dopamine uptake and release in spite of the fact that dopaminergic cells in the prenatal midbrain do not express the classical oestrogen receptor. |
1998-10-08 |
2023-08-12 |
mouse |
| C Beyer, H Raa. Nongenomic effects of oestrogen: embryonic mouse midbrain neurones respond with a rapid release of calcium from intracellular stores. The European journal of neuroscience. vol 10. issue 1. 1998-10-08. PMID:9753134. |
it is suggested that oestrogen effects on differentiation and function of midbrain dopaminergic neurones are mediated by intracellular ca2+ signalling. |
1998-10-08 |
2023-08-12 |
mouse |
| L Björklund, I Strömber. Dopaminergic growth patterns induced by striatal and cortical grafts show differences in sensitivity to increased striatal trophic activity induced by haloperidol. Journal of neuroscience research. vol 53. issue 2. 1998-09-24. PMID:9671973. |
in this paper we have studied dopaminergic growth patterns by evaluating tyrosine hydroxylase (th)-positive growth from mature midbrain dopaminergic neurons innervating grafted fetal lateral ganglionic eminence (lge) or fetal cortical tissue implanted into the dorsal striatum. |
1998-09-24 |
2023-08-12 |
Not clear |
| L Björklund, I Strömber. Dopaminergic growth patterns induced by striatal and cortical grafts show differences in sensitivity to increased striatal trophic activity induced by haloperidol. Journal of neuroscience research. vol 53. issue 2. 1998-09-24. PMID:9671973. |
taken together, the results suggest that both the patchy and diffuse growth patterns may be induced from adult midbrain dopaminergic neurons depending on the target of innervation, and that increased striatal trophic activity due to blockade of the dopaminergic input stimulates growth from a subpopulation of dopaminergic neurons that produce the nonpatchy growth. |
1998-09-24 |
2023-08-12 |
Not clear |
| H Enomoto, T Araki, A Jackman, R O Heuckeroth, W D Snider, E M Johnson, J Milbrand. GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys. Neuron. vol 21. issue 2. 1998-09-17. PMID:9728913. |
midbrain dopaminergic and motor neurons in gfr alpha1 null mice were normal. |
1998-09-17 |
2023-08-12 |
mouse |
| B Gronier, K Rasmusse. Activation of midbrain presumed dopaminergic neurones by muscarinic cholinergic receptors: an in vivo electrophysiological study in the rat. British journal of pharmacology. vol 124. issue 3. 1998-09-16. PMID:9647468. |
activation of midbrain presumed dopaminergic neurones by muscarinic cholinergic receptors: an in vivo electrophysiological study in the rat. |
1998-09-16 |
2023-08-12 |
rat |
| A Bonci, P Grillner, N B Mercuri, G Bernard. L-Type calcium channels mediate a slow excitatory synaptic transmission in rat midbrain dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 17. 1998-09-09. PMID:9712641. |
l-type calcium channels mediate a slow excitatory synaptic transmission in rat midbrain dopaminergic neurons. |
1998-09-09 |
2023-08-12 |
rat |
| A Bonci, P Grillner, N B Mercuri, G Bernard. L-Type calcium channels mediate a slow excitatory synaptic transmission in rat midbrain dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 17. 1998-09-09. PMID:9712641. |
taken together, these results indicate that under certain patterns of synaptic activity, l-type ca2+ channels regulate the synaptic release of excitatory amino acids on the dopaminergic neurons of the ventral mesencephalon. |
1998-09-09 |
2023-08-12 |
rat |
| T J Counihan, J B Penne. Regional dopamine transporter gene expression in the substantia nigra from control and Parkinson's disease brains. Journal of neurology, neurosurgery, and psychiatry. vol 65. issue 2. 1998-08-20. PMID:9703165. |
to test the hypothesis that differential regional dopamine transporter (dat) gene expression may underlie the selective vulnerability of certain nigral dopaminergic neurons in parkinson's disease, dat mrna expression was examined in neuronal subpopulations of human postmortem ventral mesencephalon from patients with parkinson's disease and controls. |
1998-08-20 |
2023-08-12 |
human |
| L R Lucas, P Pompei, J Ono, B S McEwe. Effects of adrenal steroids on basal ganglia neuropeptide mRNA and tyrosine hydroxylase radioimmunoreactive levels in the adrenalectomized rat. Journal of neurochemistry. vol 71. issue 2. 1998-08-19. PMID:9681476. |
there were no significant treatment effects on indirect markers of midbrain dopaminergic activity, i.e., cck mrna and th-ric. |
1998-08-19 |
2023-08-12 |
rat |
| J Sautter, M Meyer, C Spenger, R W Seiler, H R Widme. Effects of combined BDNF and GDNF treatment on cultured dopaminergic midbrain neurons. Neuroreport. vol 9. issue 6. 1998-08-13. PMID:9601674. |
effects of combined bdnf and gdnf treatment on cultured dopaminergic midbrain neurons. |
1998-08-13 |
2023-08-12 |
rat |
| A Ho, M Blu. Induction of interleukin-1 associated with compensatory dopaminergic sprouting in the denervated striatum of young mice: model of aging and neurodegenerative disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 15. 1998-08-07. PMID:9671653. |
young mice challenged with the neurotoxin 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (mptp), which selectively destroys the substantia nigra dopaminergic neurons in the midbrain, exhibit spontaneous recovery of dopaminergic nerve terminals. |
1998-08-07 |
2023-08-12 |
mouse |