| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A D Zurn, L Winkel, A Menoud, K Djabali, P Aebische. Combined effects of GDNF, BDNF, and CNTF on motoneuron differentiation in vitro. Journal of neuroscience research. vol 44. issue 2. 1996-09-26. PMID:8723221. |
we have previously shown that glial cell line-derived neurotrophic factor (gdnf), in addition to promoting the survival of dopaminergic neurons in cultures from embryonic rat ventral mesencephalon,also increases the activity of choline acetyltransferase (chat) in the cranial motoneurons present in these cultures (zurn et al. |
1996-09-26 |
2023-08-12 |
human |
| M P Viveros, C de Cabo, M I Colado, M I Martí. Naltrexone administration during the preweanling period affects striatal and hypothalamic serotonergic systems, but not midbrain serotonergic or striatal dopaminergic systems in the adult rat. Neuroscience letters. vol 201. issue 3. 1996-09-26. PMID:8786838. |
naltrexone administration during the preweanling period affects striatal and hypothalamic serotonergic systems, but not midbrain serotonergic or striatal dopaminergic systems in the adult rat. |
1996-09-26 |
2023-08-12 |
rat |
| M P Viveros, C de Cabo, M I Colado, M I Martí. Naltrexone administration during the preweanling period affects striatal and hypothalamic serotonergic systems, but not midbrain serotonergic or striatal dopaminergic systems in the adult rat. Neuroscience letters. vol 201. issue 3. 1996-09-26. PMID:8786838. |
we have recently reported that daily administration from birth of the opioid antagonist naltrexone (1 mg/kg, s.c.) affected dopaminergic and serotonergic systems in the striatum, hypothalamus and midbrain in rats of 7, 14 and 22 days of age. |
1996-09-26 |
2023-08-12 |
rat |
| M P Viveros, C de Cabo, M I Colado, M I Martí. Naltrexone administration during the preweanling period affects striatal and hypothalamic serotonergic systems, but not midbrain serotonergic or striatal dopaminergic systems in the adult rat. Neuroscience letters. vol 201. issue 3. 1996-09-26. PMID:8786838. |
however, no effects were found on midbrain serotonergic or striatal dopaminergic systems. |
1996-09-26 |
2023-08-12 |
rat |
| H Sawada, T Kawamura, S Shimohama, A Akaike, J Kimur. Different mechanisms of glutamate-induced neuronal death between dopaminergic and non-dopaminergic neurons in rat mesencephalic culture. Journal of neuroscience research. vol 43. issue 4. 1996-09-04. PMID:8699537. |
in the cultured embryonic rat mesencephalon, we investigated the dopaminergic and non-dopaminergic neuronal death induced by glutamate and by no-generating agents. |
1996-09-04 |
2023-08-12 |
rat |
| C Holmes, S A Jones, S A Greenfiel. The influence of target and non-target brain regions on the development of mid-brain dopaminergic neurons in organotypic slice culture. Brain research. Developmental brain research. vol 88. issue 2. 1996-08-05. PMID:8665668. |
the development and regeneration of rat dopaminergic neurons of the ventral mesencephalon was studied in organotypic slice cultures. |
1996-08-05 |
2023-08-12 |
rat |
| J G Pichel, L Shen, H Z Sheng, A C Granholm, J Drago, A Grinberg, E J Lee, S P Huang, M Saarma, B J Hoffer, H Sariola, H Westpha. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature. vol 382. issue 6586. 1996-08-01. PMID:8657307. |
glial-lial-cell-line-derived neurotrophic factor (gdnf) has been isolated as neurotrophic factor for midbrain dopaminergic neurons. |
1996-08-01 |
2023-08-12 |
mouse |
| M W Moore, R D Klein, I Fariñas, H Sauer, M Armanini, H Phillips, L F Reichardt, A M Ryan, K Carver-Moore, A Rosentha. Renal and neuronal abnormalities in mice lacking GDNF. Nature. vol 382. issue 6586. 1996-08-01. PMID:8657308. |
glial cell-line derived neurotrophic factor (gdnf) is a potent survival factor for embryonic midbrain dopaminergic, spinal motor, cranial sensory, sympathetic, and hindbrain noradrenergic neurons, and is available to these cells in vivo. |
1996-08-01 |
2023-08-12 |
mouse |
| M W Moore, R D Klein, I Fariñas, H Sauer, M Armanini, H Phillips, L F Reichardt, A M Ryan, K Carver-Moore, A Rosentha. Renal and neuronal abnormalities in mice lacking GDNF. Nature. vol 382. issue 6586. 1996-08-01. PMID:8657308. |
here we show that at postnatal day 0 (p0), gdnf-deficient mice have deficits in dorsal root ganglion, sympathetic and nodose neurons, but not in hindbrain noradrenergic or midbrain dopaminergic neurons. |
1996-08-01 |
2023-08-12 |
mouse |
| B Y Zeng, P Jenner, C D Marsde. Altered motor function and graft survival produced by basic fibroblast growth factor in rats with 6-OHDA lesions and fetal ventral mesencephalic grafts are associated with glial proliferation. Experimental neurology. vol 139. issue 2. 1996-07-31. PMID:8654524. |
we have investigated the effect of treating fetal ventral mesencephalon with bfgf or nerve growth factor (ngf) on the subsequent survival and function of grafted dopaminergic neurons implanted into the striatum of rats with a unilateral 6-hydroxydopamine lesion. |
1996-07-31 |
2023-08-12 |
rat |
| M A Elwan, M R Solima. Changes in methionine-enkephalin levels in specific rat brain regions following repeated treatment with selective dopaminergic agonists and antagonists. Life sciences. vol 58. issue 1. 1996-06-24. PMID:8628109. |
the present study was conducted to investigate the effects of repeated treatment with selective dopaminergic agents on the level of methionine-enkephalin (met-enk) in rat brain cortex (ctx), hypothalamus, (hypo), hippocampus (hipp) and midbrain (mid). |
1996-06-24 |
2023-08-12 |
rat |
| P Damier, A Kastner, Y Agid, E C Hirsc. Does monoamine oxidase type B play a role in dopaminergic nerve cell death in Parkinson's disease? Neurology. vol 46. issue 5. 1996-06-21. PMID:8628464. |
mao-b-positive dopaminergic neurons were present in all dopaminergic groups of the control midbrain. |
1996-06-21 |
2023-08-12 |
human |
| S M Waters, C S Konkoy, T P Davi. Haloperidol and apomorphine differentially affect neuropeptidase activity. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613907. |
in view of the interaction between mesocorticolimbic dopamine neurons and neuropeptides, e.g., substance p, neurotensin and enkephalins, neuroleptic-induced alterations in the activities of neuropeptidases, and thus neuropeptide metabolism can, in turn, play a role in modulating midbrain dopaminergic activity. |
1996-06-06 |
2023-08-12 |
rat |
| K Krieglstein, C Suter-Crazzolara, G Hötten, J Pohl, K Unsicke. Trophic and protective effects of growth/differentiation factor 5, a member of the transforming growth factor-beta superfamily, on midbrain dopaminergic neurons. Journal of neuroscience research. vol 42. issue 5. 1996-04-30. PMID:8600306. |
trophic and protective effects of growth/differentiation factor 5, a member of the transforming growth factor-beta superfamily, on midbrain dopaminergic neurons. |
1996-04-30 |
2023-08-12 |
human |
| K Krieglstein, C Suter-Crazzolara, G Hötten, J Pohl, K Unsicke. Trophic and protective effects of growth/differentiation factor 5, a member of the transforming growth factor-beta superfamily, on midbrain dopaminergic neurons. Journal of neuroscience research. vol 42. issue 5. 1996-04-30. PMID:8600306. |
we show here that gdf5 is expresed in the developing cns including the mesencephalon and acts as a neurotrophic, survival promoting molecule for rat dopaminergic midbrain neurons, which degenerate in parkinson's disease. |
1996-04-30 |
2023-08-12 |
human |
| K Krieglstein, C Suter-Crazzolara, G Hötten, J Pohl, K Unsicke. Trophic and protective effects of growth/differentiation factor 5, a member of the transforming growth factor-beta superfamily, on midbrain dopaminergic neurons. Journal of neuroscience research. vol 42. issue 5. 1996-04-30. PMID:8600306. |
recombinant human gdf5 supports dopaminergic neurons, dissected at embryonic day (e) 14 and cultured for 8 days under serum-free conditions, to almost the same extent as tgf-beta 3, and is as effective as glial cell line-derived neurotrophic factor (gdnf), two established trophic factors for midbrain dopaminergic neurons. |
1996-04-30 |
2023-08-12 |
human |
| B Brugg, P P Michel, Y Agid, M Ruber. Ceramide induces apoptosis in cultured mesencephalic neurons. Journal of neurochemistry. vol 66. issue 2. 1996-04-03. PMID:8592146. |
the death of dopaminergic and other neurons in primary cultures of the mesencephalon could be induced by treatment with ceramide, as in lymphocytes where it mediates activation by the cytokines tumor necrosis factor-alpha and interleukin-1 beta of a novel sphingomyelin-dependent signaling pathway leading to apoptosis. |
1996-04-03 |
2023-08-12 |
Not clear |
| M B Mattammal, J H Haring, H D Chung, G Raghu, R Stron. An endogenous dopaminergic neurotoxin: implication for Parkinson's disease. Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. vol 4. issue 3. 1996-03-15. PMID:8581559. |
the toxicity of dopal for dopaminergic neurons was investigated using rat neostriatal synaptosomes, pc-12 cells and cultures of fetal rat dissociated mesencephalon. |
1996-03-15 |
2023-08-12 |
rat |
| R von Coelln, K Unsicker, K Krieglstei. Screening of interleukins for survival-promoting effects on cultured mesencephalic dopaminergic neurons from embryonic rat brain. Brain research. Developmental brain research. vol 89. issue 1. 1996-03-14. PMID:8575089. |
in order to evaluate the neurotrophic potential that interleukins may have for nigrostriatal dopaminergic neurons, we have applied the interleukins 1 alpha, 1 beta, and 2 through 12 to cultures of e14 rat midbrain floor cells enriched for dopaminergic neurons. |
1996-03-14 |
2023-08-12 |
rat |
| J Rohrbacher, K Krieglstein, S Honerkamp, A Lewen, U Misgel. 5,7-Dihydroxytryptamine uptake discriminates living serotonergic cells from dopaminergic cells in rat midbrain culture. Neuroscience letters. vol 199. issue 3. 1996-03-13. PMID:8577399. |
5,7-dihydroxytryptamine uptake discriminates living serotonergic cells from dopaminergic cells in rat midbrain culture. |
1996-03-13 |
2023-08-12 |
rat |