| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Ostergaard, I E Holm, J Zimme. Tyrosine hydroxylase and acetylcholinesterase in the domestic pig mesencephalon: an immunocytochemical and histochemical study. The Journal of comparative neurology. vol 322. issue 2. 1992-10-14. PMID:1355778. |
we anticipate that the present description of the cellular organization of the th-i dopaminergic areas in the domestic pig ventral mesencephalon will be useful for the development of a nonprimate, large animal, experimental model of parkinson's disease. |
1992-10-14 |
2023-08-11 |
Not clear |
| K Shimoda, Y Sauve, A Marini, J P Schwartz, J W Commission. A high percentage yield of tyrosine hydroxylase-positive cells from rat E14 mesencephalic cell culture. Brain research. vol 586. issue 2. 1992-10-09. PMID:1355697. |
in the ventral mesencephalon of the e14 rat fetus, 90% of the dopaminergic, tyrosine hydroxylase positive (th+) cells are localized in 1.0 mm3 of tissue. |
1992-10-09 |
2023-08-11 |
rat |
| N B Mercuri, P Calabresi, G Bernard. The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area. Life sciences. vol 51. issue 10. 1992-09-29. PMID:1355254. |
electrophysiological experiments which study the activity of single dopaminergic neurons in the ventral mesencephalon have shown that dopamine and dopaminergic drugs reduce the firing frequency of these cells. |
1992-09-29 |
2023-08-11 |
Not clear |
| N B Mercuri, P Calabresi, G Bernard. The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area. Life sciences. vol 51. issue 10. 1992-09-29. PMID:1355254. |
in this review, we will briefly examine the literature concerning the physiological and behavioural responses caused by dopamine and dopaminergic agents on the dopaminergic neurons of the ventral mesencephalon. |
1992-09-29 |
2023-08-11 |
Not clear |
| N B Mercuri, P Calabresi, G Bernard. The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area. Life sciences. vol 51. issue 10. 1992-09-29. PMID:1355254. |
our conclusion suggests that the electrophysiological actions of dopamine and dopamine-related drugs on dopaminergic cells in the ventral mesencephalon might be indicative of the pharmacological effects of these agents on the brain. |
1992-09-29 |
2023-08-11 |
Not clear |
| N B Mercuri, F Stratta, P Calabresi, G Bernard. Electrophysiological evidence for the presence of ionotropic and metabotropic excitatory amino acid receptors on dopaminergic neurons of the rat mesencephalon: an in vitro study. Functional neurology. vol 7. issue 3. 1992-09-17. PMID:1323507. |
electrophysiological evidence for the presence of ionotropic and metabotropic excitatory amino acid receptors on dopaminergic neurons of the rat mesencephalon: an in vitro study. |
1992-09-17 |
2023-08-11 |
rat |
| N B Mercuri, F Stratta, P Calabresi, G Bernard. Electrophysiological evidence for the presence of ionotropic and metabotropic excitatory amino acid receptors on dopaminergic neurons of the rat mesencephalon: an in vitro study. Functional neurology. vol 7. issue 3. 1992-09-17. PMID:1323507. |
the actions of the ionotropic and metabotropic excitatory amino acid agonists ampa, quisqualate, kainate, nmda and trans-acdp were studied by means of intracellular electrophysiological recordings from dopaminergic neurons of rat mesencephalon in brain slices. |
1992-09-17 |
2023-08-11 |
rat |
| C B Jaeger, P Aebischer, P A Tresco, S R Winn, L A Green. Growth of tumour cell lines in polymer capsules: ultrastructure of encapsulated PC12 cells. Journal of neurocytology. vol 21. issue 7. 1992-09-11. PMID:1500946. |
recent studies indicate that polymer-encapsulated pc12 cells release sufficient amounts of dopamine to significantly alter behavioural paradigms in animals with unilateral lesions of dopaminergic midbrain neurons. |
1992-09-11 |
2023-08-11 |
rat |
| A Kastner, E C Hirsch, O Lejeune, F Javoy-Agid, O Rascol, Y Agi. Is the vulnerability of neurons in the substantia nigra of patients with Parkinson's disease related to their neuromelanin content? Journal of neurochemistry. vol 59. issue 3. 1992-09-09. PMID:1494900. |
to test whether the amount of pigment per cell is a critical factor or whether the presence of nm within a neuron is sufficient to account for the degeneration of dopaminergic neurons, the nm content was measured in each neuron from representative sections throughout the ventral mesencephalon of four controls subjects and four patients with pd. |
1992-09-09 |
2023-08-11 |
human |
| S Brené, N Lindefors, H Persso. Midbrain dopamine neurons regulate preprotachykinin-A mRNA expression in the rat forebrain during development. Brain research. Molecular brain research. vol 14. issue 1-2. 1992-09-08. PMID:1323010. |
the midbrain dopaminergic lesion caused a 22-25% increase in the level of ppt-a mrna in cingulate cortex and frontoparietal cortex when analysed at 2 weeks of age, compared to saline-injected control animals. |
1992-09-08 |
2023-08-11 |
rat |
| D C German, K F Manaye, P K Sonsalla, B A Brook. Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells. Annals of the New York Academy of Sciences. vol 648. 1992-08-21. PMID:1353337. |
midbrain dopaminergic cell loss in parkinson's disease and mptp-induced parkinsonism: sparing of calbindin-d28k-containing cells. |
1992-08-21 |
2023-08-11 |
mouse |
| D C German, K F Manaye, P K Sonsalla, B A Brook. Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells. Annals of the New York Academy of Sciences. vol 648. 1992-08-21. PMID:1353337. |
computer imaging and immunohistochemical staining techniques were used to determine which midbrain dopaminergic (da) cells are spared in parkinson's disease (pd), and in animals treated with the da neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), and whether the spared cells contain the calcium-binding protein, calbindin-d28k (cabp). |
1992-08-21 |
2023-08-11 |
mouse |
| C Heidbreder, M Gewiss, S Lallemand, B P Roques, P De Witt. Inhibition of enkephalin metabolism and activation of mu- or delta-opioid receptors elicit opposite effects on reward and motility in the ventral mesencephalon. Neuropharmacology. vol 31. issue 3. 1992-08-20. PMID:1321359. |
the coexistence of endogenous opioid systems and dopaminergic neurones in the midbrain tegmental area suggests functional interactions between dopamine and enkephalins. |
1992-08-20 |
2023-08-11 |
rat |
| J Woulfe, A Beaude. Neurotensin terminals form synapses primarily with neurons lacking detectable tyrosine hydroxylase immunoreactivity in the rat substantia nigra and ventral tegmental area. The Journal of comparative neurology. vol 321. issue 1. 1992-07-30. PMID:1351897. |
these results are interpreted in light of the selective association of neurotensin receptors with dopaminergic neurons in the substantia nigra and ventral tegmental area to suggest a predominantly parasynaptic mechanism of action for neurotensin in the ventral midbrain. |
1992-07-30 |
2023-08-11 |
rat |
| H W Berendse, H J Groenewegen, A H Lohma. Compartmental distribution of ventral striatal neurons projecting to the mesencephalon in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 6. 1992-07-17. PMID:1607929. |
the projections from the ventral striatum to the dopaminergic cell groups in the ventral mesencephalon and those to the substantia nigra pars reticulata originate from distinct subpopulations of ventral striatal neurons that respect neurochemically defined compartmental boundaries. |
1992-07-17 |
2023-08-11 |
rat |
| X Gu, A L Blatz, D C Germa. Subtypes of substantia nigra dopaminergic neurons revealed by apamin: autoradiographic and electrophysiological studies. Brain research bulletin. vol 28. issue 3. 1992-06-29. PMID:1350500. |
to test whether sk channels reside within the midbrain dopaminergic cell regions of the mouse, receptor autoradiographic experiments were conducted with the sk channel antagonist, 125i-apamin. |
1992-06-29 |
2023-08-11 |
mouse |
| D M Wallace, D J Magnuson, T S Gra. Organization of amygdaloid projections to brainstem dopaminergic, noradrenergic, and adrenergic cell groups in the rat. Brain research bulletin. vol 28. issue 3. 1992-06-29. PMID:1591601. |
the results demonstrate that the amygdala primarily innervates the dopaminergic cells of midbrain (i.e., a8 and lateral a9 cells) and the adrenergic cells (c2) and noradrenergic (a2) cells in the nucleus of the solitary tract. |
1992-06-29 |
2023-08-11 |
rat |
| I Chaudieu, H Mount, R Quirion, P Boks. Transient postnatal increases in excitatory amino acid binding sites in rat ventral mesencephalon. Neuroscience letters. vol 133. issue 2. 1992-06-26. PMID:1667817. |
these results raise the possibility that the transient overexpression of eaa receptors in the ventral mesencephalon may affect the developmental fate of dopaminergic and other neurons in this region. |
1992-06-26 |
2023-08-11 |
rat |
| C W Shults, L Alberti, T A Kimber, W B Stallcu. Mesostriatal dopaminergic axons transiently express high levels of NILE during development. Experimental neurology. vol 116. issue 3. 1992-06-25. PMID:1350253. |
in the postnatal brain, nile-ir material no longer clearly outlined the fascicles of dopaminergic axons as they ran from the mesencephalon to the striatum. |
1992-06-25 |
2023-08-11 |
rat |
| C W Shults, T A Kimbe. Mesencephalic dopaminergic cells exhibit increased density of neural cell adhesion molecule and polysialic acid during development. Brain research. Developmental brain research. vol 65. issue 2. 1992-06-01. PMID:1349268. |
in the developing mesencephalon of the rat, the dopaminergic neurons are generated in the ventricular zone of the basal plate between e11 and e15 and then migrate along radial glia to the ventral surface of the developing mesencephalon. |
1992-06-01 |
2023-08-11 |
rat |