| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Brouwer, H Van Dijken, M H Ruiters, J D Van Willigen, G J Ter Hors. Localization of dopamine D2 receptor mRNA with non-radioactive in situ hybridization histochemistry. Neuroscience letters. vol 142. issue 2. 1993-01-06. PMID:1454220. |
positive in situ hybridization signals were also found in dopamine cell groups of the substantia nigra and ventral tegmental area and in regions where a dopaminergic innervation is controversial, like the cerebellar cortex and the hippocampus. |
1993-01-06 |
2023-08-11 |
rat |
| G Hu, Y Hu, G Z Ji. Effects of l-stepholidine on synaptosomal Ca(2+)-ATPase and subcellular calmodulin in rat striatum. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 13. issue 4. 1992-12-31. PMID:1456049. |
these results suggest that l-spd may modulate the release and synthesis of dopamine (da) and the negative feedback regulation of presynaptic da receptors by altering ca2+ and cam regulating processes in the central dopaminergic nervous system. |
1992-12-31 |
2023-08-11 |
rat |
| T Florio, M G Pan, B Newman, R E Hershberger, O Civelli, P J Stor. Dopaminergic inhibition of DNA synthesis in pituitary tumor cells is associated with phosphotyrosine phosphatase activity. The Journal of biological chemistry. vol 267. issue 34. 1992-12-30. PMID:1360008. |
we suggest that the anti-proliferative action of dopamine is mediated, at least in part, by the dopaminergic stimulation of a phosphotyrosine phosphatase. |
1992-12-30 |
2023-08-11 |
human |
| G H Jones, T W Robbin. Differential effects of mesocortical, mesolimbic, and mesostriatal dopamine depletion on spontaneous, conditioned, and drug-induced locomotor activity. Pharmacology, biochemistry, and behavior. vol 43. issue 3. 1992-12-30. PMID:1448483. |
these results differentiate the role of pfc, nac, and cpu dopamine in spontaneous, conditioned, and drug-induced locomotor activity and further implicate dopaminergic mechanisms of the nac in the magnitude of the behavioural response to incentive stimuli. |
1992-12-30 |
2023-08-11 |
human |
| b' R R Ga\\xc4\\xadnetdinov, M B Bogdanov, V S Kudrin, K S Raevski\\xc4\\xa. [Selective analyzers of dopamine D2 receptors modulate serotonin metabolism in the striatum and nucleus accumbens of the rat brain during blockade of dopaminergic impulse flow]. Biulleten\' eksperimental\'noi biologii i meditsiny. vol 113. issue 6. 1992-12-24. PMID:1359911.' |
[selective analyzers of dopamine d2 receptors modulate serotonin metabolism in the striatum and nucleus accumbens of the rat brain during blockade of dopaminergic impulse flow]. |
1992-12-24 |
2023-08-11 |
rat |
| b' R R Ga\\xc4\\xadnetdinov, M B Bogdanov, V S Kudrin, K S Raevski\\xc4\\xa. [Selective analyzers of dopamine D2 receptors modulate serotonin metabolism in the striatum and nucleus accumbens of the rat brain during blockade of dopaminergic impulse flow]. Biulleten\' eksperimental\'noi biologii i meditsiny. vol 113. issue 6. 1992-12-24. PMID:1359911.' |
gbl as well as dopamine d2 receptor selective drugs were shown not only to change neurochemical parameters of dopaminergic brain systems, but also to modulate serotonin metabolism without affecting its biosynthesis. |
1992-12-24 |
2023-08-11 |
rat |
| M Virno, A Gazzaniga, L Taverniti, J Pecori Giraldi, F De Gregori. Dopamine, dopaminergic drugs and ocular hypertension. International ophthalmology. vol 16. issue 4-5. 1992-12-23. PMID:1358853. |
dopamine, dopaminergic drugs and ocular hypertension. |
1992-12-23 |
2023-08-11 |
Not clear |
| M Virno, A Gazzaniga, L Taverniti, J Pecori Giraldi, F De Gregori. Dopamine, dopaminergic drugs and ocular hypertension. International ophthalmology. vol 16. issue 4-5. 1992-12-23. PMID:1358853. |
the substances taken in consideration were: dopamine, ibopamine (dopamine analog), fenoldopam and 3b90 (d1-receptor agonists) and bromocriptine (dopaminergic agonist with higher affinity for d2 than for d1-receptors). |
1992-12-23 |
2023-08-11 |
Not clear |
| M Navarro, J J Fernández-Ruiz, F Rodriguez de Fonseca, M L Hernández, M Cebeira, J A Ramo. Modifications of striatal D2 dopaminergic postsynaptic sensitivity during development of morphine tolerance-dependence in mice. Pharmacology, biochemistry, and behavior. vol 43. issue 2. 1992-12-22. PMID:1332081. |
striatal dopaminergic activity was evaluated by measuring: a) the ratio between the amounts of l-3,4-dihydroxyphenylacetic acid (dopac), the main intraneuronal metabolite of dopamine (da), and the neurotransmitter itself, as an index of presynaptic activity; and b) the number and affinity of d1 and d2 dopaminergic receptors, as well as the amount of their coupled second messenger, cyclic adenosine monophosphate (camp), as postsynaptic parameters. |
1992-12-22 |
2023-08-11 |
mouse |
| S H Shin, R L Heisle. High concentrations of dopamine and epinephrine protect dopaminergic D2 receptors from inactivation by phenoxybenzamine on primary cultured rat lactotrophs. Neuroendocrinology. vol 56. issue 3. 1992-12-22. PMID:1436379. |
high concentrations of dopamine and epinephrine protect dopaminergic d2 receptors from inactivation by phenoxybenzamine on primary cultured rat lactotrophs. |
1992-12-22 |
2023-08-11 |
rat |
| M Diana, G L Gessa, Z L Rossett. Lack of tolerance to ethanol-induced stimulation of mesolimbic dopamine system. Alcohol and alcoholism (Oxford, Oxfordshire). vol 27. issue 4. 1992-12-18. PMID:1329784. |
an ethanol challenge stimulated both the electrical activity of a10 dopaminergic cells and dopamine output in the ventral striatum of behaviourally tolerant animals and of controls to the same extent. |
1992-12-18 |
2023-08-11 |
rat |
| C A McCormack, B Burnsid. A role for endogenous dopamine in circadian regulation of retinal cone movement. Experimental eye research. vol 55. issue 3. 1992-12-18. PMID:1426081. |
intraocular injection studies suggest that circadian regulation of cone myoid movement is mediated locally within the eye by dopamine acting via a dopaminergic d2-receptor. |
1992-12-18 |
2023-08-11 |
Not clear |
| F W Santma. Catecholamines in critical care. The commonly used catecholamines: receptor and clinical profile, indications and dosages. Pharmaceutisch weekblad. Scientific edition. vol 14. issue 5. 1992-12-18. PMID:1437512. |
a brief physiological description of the alpha, beta and dopaminergic receptors is used in order to explain the clinical effects of norepinephrine, epinephrine, isoproterenol, dopamine, dobutamine and dopexamine. |
1992-12-18 |
2023-08-11 |
Not clear |
| X Z Zh. Development of natural products as drugs acting on central nervous system. Memorias do Instituto Oswaldo Cruz. vol 86 Suppl 2. 1992-12-17. PMID:1841995. |
results of receptor binding assay and their pre- and post-synaptic effects on dopaminergic system indicate that (-)-thp and (-)-stepholidine are dopamine receptor antagonists while (+)-thp is a selective dopamine depletor. |
1992-12-17 |
2023-08-11 |
monkey |
| G W Huntley, J H Morrison, A Prikhozhan, S C Sealfo. Localization of multiple dopamine receptor subtype mRNAs in human and monkey motor cortex and striatum. Brain research. Molecular brain research. vol 15. issue 3-4. 1992-12-14. PMID:1331674. |
thus, not only does primate neocortex possess a broader representation of the dopamine receptor subtype mrnas examined in comparison with striatum, but the unexpected presence and widespread distribution of d2 and d5 receptor mrnas in cortex suggests that, along with d1 receptors, d2 and d5 receptors play a crucial role in the dopaminergic modulation of cognition and motor behavior, and in dopamine dysfunction associated with neuropsychiatric disorders. |
1992-12-14 |
2023-08-11 |
human |
| L T Weiss-Wunder, M F Chessele. Acute and repeated administration of fluphenazine-N-mustard alters levels of tyrosine hydroxylase mRNA in subsets of mesencephalic dopaminergic neurons. Neuroscience. vol 49. issue 2. 1992-12-14. PMID:1359452. |
changes in striatal dopamine turnover and levels of tyrosine hydroxylase messenger rna were examined in mice injected with d2 selective doses of fluphenazine-n-mustard, an irreversible blocker of dopaminergic receptors. |
1992-12-14 |
2023-08-11 |
mouse |
| S Masuko, S Nakajima, Y Nakajim. Dissociated high-purity dopaminergic neuron cultures from the substantia nigra and the ventral tegmental area of the postnatal rat. Neuroscience. vol 49. issue 2. 1992-12-14. PMID:1359454. |
co-existence of dopamine and cholecystokinin was found in about 70% of dopaminergic neurons from the substantia nigra and in about 35% of dopaminergic neurons from the ventral tegmental area. |
1992-12-14 |
2023-08-11 |
rat |
| T C Napier, J J Chroba. Evaluations of ventral pallidal dopamine receptor activation in behaving rats. Neuroreport. vol 3. issue 7. 1992-12-14. PMID:1421116. |
the magnitude of this response was related to the dopamine dose injected and the effect was attenuated by systemic pretreatment with the dopaminergic antagonist, flupentixol. |
1992-12-14 |
2023-08-11 |
rat |
| M J Landr. An overview of cocaethylene, an alcohol-derived, psychoactive, cocaine metabolite. Journal of psychoactive drugs. vol 24. issue 3. 1992-12-11. PMID:1432406. |
with a pharmacologic profile similar to cocaine, it can block the dopamine transporter on dopaminergic presynaptic nerve terminals in the brain. |
1992-12-11 |
2023-08-11 |
mouse |
| G A Hicks, G Henderso. Lack of evidence for coupling of the dopamine D2 receptor to an adenosine triphosphate-sensitive potassium (ATP-K+) channel in dopaminergic neurones of the rat substantia nigra. Neuroscience letters. vol 141. issue 2. 1992-12-11. PMID:1436636. |
lack of evidence for coupling of the dopamine d2 receptor to an adenosine triphosphate-sensitive potassium (atp-k+) channel in dopaminergic neurones of the rat substantia nigra. |
1992-12-11 |
2023-08-11 |
rat |