| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Santiago, B H Westerin. The role of GABA receptors in the control of nigrostriatal dopaminergic neurons: dual-probe microdialysis study in awake rats. European journal of pharmacology. vol 219. issue 2. 1992-12-07. PMID:1330605. |
a microdialysis probe implanted into the substantia nigra was used to infuse gamma-aminobutyric acid-ergic (gabaergic) compounds onto cell bodies/dendrites of dopaminergic neurons, while a second microdialysis probe was used to record the extracellular concentrations of dopamine and 3,4-dihydroxy-phenylacetic acid (dopac) in the ipsilateral striatum. |
1992-12-07 |
2023-08-11 |
rat |
| R R Dawirs, G Teuchert-Nood. Demonstration of dopamine-immunoreactive cells in the proximal convoluted tubule of gerbil (Meriones unguiculatus) kidney. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 40. issue 11. 1992-12-03. PMID:1431057. |
the functional significance of dopamine in these cells is discussed in relation to the present view of renal dopaminergic actions. |
1992-12-03 |
2023-08-11 |
Not clear |
| D J Vandenbergh, A M Persico, G R Uh. A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs. Brain research. Molecular brain research. vol 15. issue 1-2. 1992-12-02. PMID:1359373. |
we describe a cdna for the human dopamine transporter, which has been implicated in several human disorders linked to dopaminergic function. |
1992-12-02 |
2023-08-11 |
human |
| H Böttcher, G Barnickel, H H Hausberg, A F Haase, C A Seyfried, V Eierman. Synthesis and dopaminergic activity of some 3-(1,2,3,6-tetrahydro-1-pyridylalkyl)indoles. A novel conformational model to explain structure-activity relationships. Journal of medicinal chemistry. vol 35. issue 22. 1992-12-01. PMID:1359142. |
the synthesis and dopaminergic properties of a novel type of dopamine agonist is described. |
1992-12-01 |
2023-08-11 |
Not clear |
| J A Smith, S E Loughlin, F M Lesli. kappa-Opioid inhibition of [3H]dopamine release from rat ventral mesencephalic dissociated cell cultures. Molecular pharmacology. vol 42. issue 4. 1992-12-01. PMID:1359395. |
these results suggest that functional kappa receptors, modulating dopamine release, are localized on the terminals of dopaminergic neurons. |
1992-12-01 |
2023-08-11 |
rat |
| C J Schmidt, C K Black, V L Taylor, G M Fadayel, T M Humphreys, T R Nieduzak, S M Sorense. The 5-HT2 receptor antagonist, MDL 28,133A, disrupts the serotonergic-dopaminergic interaction mediating the neurochemical effects of 3,4-methylenedioxymethamphetamine. European journal of pharmacology. vol 220. issue 2-3. 1992-12-01. PMID:1425989. |
mdma-induced 5-ht release did not reduce the firing rate of dopaminergic neurons as assessed by dopamine depletion following synthesis inhibition with alpha-methyl-p-tyrosine (alpha-mpt). |
1992-12-01 |
2023-08-11 |
rat |
| L W Zhou, S P Zhang, S Welsh, T A Connell, B Weis. Triazolam blocks the initial rotational effects of quinpirole but permits the later developing reduction of dopamine D2-mediated rotational behavior and dopamine D2 receptors. European journal of pharmacology. vol 218. issue 2-3. 1992-11-27. PMID:1358635. |
we conclude that up-regulated dopamine receptors and dopaminergic behaviors can be reversed by the continuous administration of a dopamine receptor agonist and that this reversal can occur without producing an initial exacerbation of dopaminergic responses. |
1992-11-27 |
2023-08-11 |
mouse |
| L Churchill, M C Austin, P W Kaliva. Dopamine and endogenous opioid regulation of picrotoxin-induced locomotion in the ventral pallidum after dopamine depletion in the nucleus accumbens. Psychopharmacology. vol 108. issue 1-2. 1992-11-25. PMID:1410135. |
to investigate the regulation of vp-induced locomotion by the dopaminergic innervation of the nucleus accumbens (na) and the role of opioid receptors in this regulation, dopamine innervation of the na was bilaterally lesioned with 6-hydroxydopamine (6-ohda). |
1992-11-25 |
2023-08-11 |
rat |
| A S Undie, E Friedma. Selective dopaminergic mechanism of dopamine and SKF38393 stimulation of inositol phosphate formation in rat brain. European journal of pharmacology. vol 226. issue 4. 1992-11-23. PMID:1327844. |
selective dopaminergic mechanism of dopamine and skf38393 stimulation of inositol phosphate formation in rat brain. |
1992-11-23 |
2023-08-11 |
rat |
| D Nouel, J Costentin, D Lugrin, P Kitabgi, N Ple, D Davous. Investigations about a direct neurotensin-dopamine interaction by nuclear magnetic resonance study, synaptosomal uptake of dopamine, and binding of neurotensin to its receptors. Journal of neurochemistry. vol 59. issue 5. 1992-11-20. PMID:1328532. |
interactions between dopamine and neurotensin can occur at various levels of the dopaminergic pathways. |
1992-11-20 |
2023-08-11 |
Not clear |
| A Markou, G F Koo. Bromocriptine reverses the elevation in intracranial self-stimulation thresholds observed in a rat model of cocaine withdrawal. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 7. issue 3. 1992-11-19. PMID:1388645. |
since cocaine's rewarding effects are mediated by enhanced dopaminergic neurotransmission in the mesocorticolimbic system, it is possible that a long-acting dopamine agonist might block the withdrawal effects associated with the termination of a prolonged bout of cocaine self-administration. |
1992-11-19 |
2023-08-11 |
rat |
| E Panula-Lehto, M Mäkinen, L Ahte. Effects of taurine, homotaurine and GABA on hypothalamic and striatal dopamine metabolism. Naunyn-Schmiedeberg's archives of pharmacology. vol 346. issue 1. 1992-11-19. PMID:1407006. |
to elucidate the effects of taurine on hypothalamic and striatal dopaminergic neurotransmission we compared its effects to those of gamma-aminobutyric acid (gaba) and homotaurine (a gabaa-receptor agonist) on hypothalamic and striatal concentrations of dopamine (da) and its metabolites, 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva) and, in the case of striatum, 3-methoxytyramine (3-mt) in rats. |
1992-11-19 |
2023-08-11 |
rat |
| O Meucci, E Landolfi, A Scorziello, M Grimaldi, C Ventra, T Florio, A Avallone, G Schettin. Dopamine and somatostatin inhibition of prolactin secretion from MMQ pituitary cells: role of adenosine triphosphate-sensitive potassium channels. Endocrinology. vol 131. issue 4. 1992-11-13. PMID:1356754. |
conversely, we found that glibenclamide does not modify the dopaminergic inhibition of prl secretion and second messenger systems, suggesting that atp-sensitive potassium channels may not be involved in the inhibitory effect of dopamine on prl release. |
1992-11-13 |
2023-08-11 |
Not clear |
| K Inoue, K Nakazawa, T Watano, M Ohara-Imaizumi, K Fujimori, A Takanak. Dopamine receptor agonists and antagonists enhance ATP-activated currents. European journal of pharmacology. vol 215. issue 2-3. 1992-11-13. PMID:1383001. |
the results suggest that atp-activated channels are modulated by dopaminergic mechanisms, and that this modulation cannot be attributed to any single class of dopamine receptors. |
1992-11-13 |
2023-08-11 |
Not clear |
| M F Piercey, J T Lum, W E Hoffmann, A Carlsson, E Ljung, K Svensso. Antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-AJ76 and (+)-UH232. Brain research. vol 588. issue 2. 1992-11-13. PMID:1393576. |
the aminotetralins (+)-aj76 and (+)-uh232 are stimulant dopaminergic antagonists, which may preferentially antagonize autoreceptors of dopamine nerve terminals. |
1992-11-13 |
2023-08-11 |
Not clear |
| J W Boja, W M Mitchell, A Patel, T A Kopajtic, F I Carroll, A H Lewin, P Abraham, M J Kuha. High-affinity binding of [125I]RTI-55 to dopamine and serotonin transporters in rat brain. Synapse (New York, N.Y.). vol 12. issue 1. 1992-11-12. PMID:1411961. |
specific binding of [125i]rti-55 was blocked by dopamine uptake inhibitors in areas rich in dopaminergic nerve terminals. |
1992-11-12 |
2023-08-11 |
rat |
| H K Choi, L Won, J D Roback, B H Wainer, A Helle. Specific modulation of dopamine expression in neuronal hybrid cells by primary cells from different brain regions. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 19. 1992-11-10. PMID:1357658. |
when mn9d cells were coaggregated with primary embryonic cells of optic tectum, a brain region that does not receive a dopaminergic innervation, there was a marked reduction in their dopamine content, tyrosine hydroxylase immunoreactivity, and tyrosine hydroxylase mrna. |
1992-11-10 |
2023-08-11 |
Not clear |
| H K Choi, L Won, J D Roback, B H Wainer, A Helle. Specific modulation of dopamine expression in neuronal hybrid cells by primary cells from different brain regions. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 19. 1992-11-10. PMID:1357658. |
similar reductions in dopamine content were produced by coaggregation with cells from embryonic thalamus, another brain region devoid of dopaminergic innervation. |
1992-11-10 |
2023-08-11 |
Not clear |
| M F Suaud-Chagny, K Chergui, G Chouvet, F Gono. Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area. Neuroscience. vol 49. issue 1. 1992-11-06. PMID:1357587. |
relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area. |
1992-11-06 |
2023-08-11 |
rat |
| M F Suaud-Chagny, K Chergui, G Chouvet, F Gono. Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area. Neuroscience. vol 49. issue 1. 1992-11-06. PMID:1357587. |
this further shows that dopaminergic terminals convert physiological impulse flow into dopamine release as a high pass filter which favors bursts of action potentials. |
1992-11-06 |
2023-08-11 |
rat |