Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
T S Rao, J A Cler, S J Mick, V M Dilworth, P C Contreras, S Iyengar, P L Woo. Neurochemical characterization of dopaminergic effects of opipramol, a potent sigma receptor ligand, in vivo. Neuropharmacology. vol 29. issue 12. 1991-04-09. PMID:1963476. |
irreversible inactivation of dopamine receptors by eedq (n-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline) did not affect the opipramol-induced increases in levels of dihydroxyphenylacetic acid (dopac) in the striatum of the rat, indicating a predominant role of activation of sigma receptors in the dopaminergic effects of opipramol. |
1991-04-09 |
2023-08-11 |
mouse |
A Vaccari, E Stefanini, G de Montis, Z L Rossett. Dopaminergic dysfunction in neonatal hypothyroidism: differential effects of GM1 ganglioside. Neuropharmacology. vol 29. issue 12. 1991-04-09. PMID:2149873. |
the ganglioside-driven selective recovery of the transport and storage process of [3h]dopamine might result either from a chronically-exerted stimulation by gm1 on the na/k- and mg-atpase activities, thus reflecting on the atpase-dependent neuronal and vesicular transport processes of dopamine or from a gm1-promoted maturation of the otherwise retarded functionality of dopaminergic nerve endings in the neonatal hypothyroid striatum. |
1991-04-09 |
2023-08-11 |
rat |
J P Miell, R Corder, F P Pralong, R C Gaillar. Effects of dexamethasone on growth hormone (GH)-releasing hormone, arginine- and dopaminergic stimulated GH secretion, and total plasma insulin-like growth factor-I concentrations in normal male volunteers. The Journal of clinical endocrinology and metabolism. vol 72. issue 3. 1991-04-02. PMID:1671785. |
after dex administration, responses to both dopaminergic agents were suppressed [cv, 6.7 (4.0-21.2); p less than 0.01 vs. control response; and dopamine, 5.3 (4.8-7.9); p less than 0.05 vs. control response]. |
1991-04-02 |
2023-08-11 |
human |
N E Goeders, O J Bienvenu, E B De Souz. Chronic cocaine administration alters corticotropin-releasing factor receptors in the rat brain. Brain research. vol 531. issue 1-2. 1991-04-01. PMID:1963104. |
dopamine may also be involved in the release of crf in the rat brain since the purported loss of dopaminergic innervations resulted in increased crf binding in the saline-treated animals. |
1991-04-01 |
2023-08-11 |
rat |
C De Landsheere, D Lamott. [Methods and clinical applications of positron emission tomography in endocrinology]. Annales d'endocrinologie. vol 51. issue 3-4. 1991-04-01. PMID:2291630. |
these last tumors represent a particular entity because of several combined characteristics: high turnover rate of amino acids, high density of dopaminergic receptors and response to bromocriptine (analogue of dopamine inhibiting the secretion of prolactin) in relation to the level of receptors. |
1991-04-01 |
2023-08-11 |
Not clear |
N Cuenca, E Fernández, H Kol. Distribution of immunoreactivity to protein kinase C in the turtle retina. Brain research. vol 532. issue 1-2. 1991-03-21. PMID:2282521. |
incubation with dopamine, in particular, brings out the putative dopaminergic amacrine cell. |
1991-03-21 |
2023-08-11 |
Not clear |
G L Bernardini, S G Speciale, D C Germa. Increased midbrain dopaminergic cell activity following 2'CH3-MPTP-induced dopaminergic cell loss: an in vitro electrophysiological study. Brain research. vol 527. issue 1. 1991-03-19. PMID:1980838. |
several days after the administration of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'ch3-mptp) to the balb/cj mouse there is a loss of midbrain dopaminergic neurons, a reduction of forebrain dopamine (da) content, and an elevation in forebrain da turnover. |
1991-03-19 |
2023-08-11 |
mouse |
P A Kempster, J P Frankel, G M Stern, A J Lee. Comparison of motor response to apomorphine and levodopa in Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. vol 53. issue 11. 1991-03-18. PMID:2283512. |
these clinical observations support the notion that integrity of striatal post-synaptic dopamine receptors is a key determinant of responsiveness to dopaminergic treatment in parkinson's disease. |
1991-03-18 |
2023-08-11 |
Not clear |
M N Castel, A Boireau, P M Laduro. Effect of gamma-butyrolactone on the retrograde axonal transport of neurotensin in dopaminergic neurones. European journal of pharmacology. vol 186. issue 1. 1991-03-15. PMID:1704309. |
gamma-butyrolactone is a drug known to inhibit the flow of electrical impulses in dopaminergic neurones and to prevent dopamine release in the striatum. |
1991-03-15 |
2023-08-11 |
rat |
M N Castel, A Boireau, P M Laduro. Effect of gamma-butyrolactone on the retrograde axonal transport of neurotensin in dopaminergic neurones. European journal of pharmacology. vol 186. issue 1. 1991-03-15. PMID:1704309. |
we therefore conclude that the retrograde axonal transport of neurotensin in the nigrostriatal pathway is not affected by reduced dopaminergic firing or by inhibition of the striatal release of dopamine. |
1991-03-15 |
2023-08-11 |
rat |
K P Gudehithlu, A M Duchemin, G A Tejwani, N H Neff, M Hadjiconstantino. Preproenkephalin mRNA and methionine-enkephalin increase in mouse striatum after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment. Journal of neurochemistry. vol 56. issue 3. 1991-03-15. PMID:1899692. |
pretreatment with the monoamine oxidase b inhibitor deprenyl or the dopamine transport blocker nomifensine prevented these changes, suggesting that the changes were related to the partial loss of dopaminergic neurons rather than to mptp. |
1991-03-15 |
2023-08-11 |
mouse |
W Kolbinger, K Kohler, H Oetting, R Weile. Endogenous dopamine and cyclic events in the fish retina, I: HPLC assay of total content, release, and metabolic turnover during different light/dark cycles. Visual neuroscience. vol 5. issue 2. 1991-03-13. PMID:2278941. |
dopaminergic activity was measured during different light/dark cycles, during continuous darkness, and during short-term light and dark adaptation within 1 h. during a 12-h light/12-h dark cycle, the total content of endogenous dopamine was high during the dark phase and low during the light phase. |
1991-03-13 |
2023-08-11 |
Not clear |
W Kolbinger, K Kohler, H Oetting, R Weile. Endogenous dopamine and cyclic events in the fish retina, I: HPLC assay of total content, release, and metabolic turnover during different light/dark cycles. Visual neuroscience. vol 5. issue 2. 1991-03-13. PMID:2278941. |
the concentration of the dopamine breakdown product 3,4-dihydroxyphenylacetic acid (dopac), which reflects the endogenous dopaminergic activity, was high during the light phase and low during the dark phase. |
1991-03-13 |
2023-08-11 |
Not clear |
J Luthman, E Brodin, E Sundström, B Wiehage. Studies on brain monoamine and neuropeptide systems after neonatal intracerebroventricular 6-hydroxydopamine treatment. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 8. issue 5. 1991-03-08. PMID:1704172. |
in order to study the effects of a neonatal dopamine lesion on dopaminergic, serotonergic and peptidergic systems, sprague-dawley rats were treated by intracerebroventricular administration of 6-hydroxydopamine (100 micrograms, days 3 and 6) following desipramine pretreatment (25 mg/kg s.c.). |
1991-03-08 |
2023-08-11 |
rat |
B Knüsel, J W Winslow, A Rosenthal, L E Burton, D P Seid, K Nikolics, F Heft. Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 3. 1991-03-08. PMID:1992488. |
in contrast to ngf, which does not affect central dopaminergic neurons, rhbdnf increased dopamine uptake activity. |
1991-03-08 |
2023-08-11 |
human |
D J Wiedemann, A Basse-Tomusk, R L Wilson, G V Rebec, R M Wightma. Interference by DOPAC and ascorbate during attempts to measure drug-induced changes in neostriatal dopamine with Nafion-coated, carbon-fiber electrodes. Journal of neuroscience methods. vol 35. issue 1. 1991-03-06. PMID:2148961. |
voltammetric detection of dopamine was possible, however, during electrical stimulation of dopaminergic afferents in the medial forebrain bundle. |
1991-03-06 |
2023-08-11 |
rat |
X P Xia, B D Chen, Z Sun, G Z Ji. [Ocular hypotensive action of l-stepholidine]. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 11. issue 2. 1991-02-28. PMID:2125799. |
as the ciliary process of the eye behaves much like the renal glomerulus, dopamine increases the glomerular blood flow and dopaminergic antagonist decreases it, the mechanism of l-spd in lowering intraocular pressure may be related to the dopaminergic receptor blocking effect of it. |
1991-02-28 |
2023-08-11 |
Not clear |
I Shimizu, C Prasa. Relationship between [3H]mazindol binding to dopamine uptake sites and [3H]dopamine uptake in rat striatum during aging. Journal of neurochemistry. vol 56. issue 2. 1991-02-26. PMID:1988557. |
to investigate the role of mazindol binding sites in the dopamine uptake process and the fate of these sites (labeling dopaminergic neurons) during aging, we have examined the properties of mazindol binding and dopamine uptake in individual young and old rats. |
1991-02-26 |
2023-08-11 |
rat |
M D Bates, S E Senogles, J R Bunzow, S B Liggett, O Civelli, M G Caro. Regulation of responsiveness at D2 dopamine receptors by receptor desensitization and adenylyl cyclase sensitization. Molecular pharmacology. vol 39. issue 1. 1991-02-19. PMID:1846220. |
treatment of these cells with the d2 agonist quinpirole (1 microm) resulted in desensitization of dopaminergic inhibition of forskolin-stimulated camp accumulation, with a approximately 4-fold decrease in the potency of dopamine after 1 hr of treatment. |
1991-02-19 |
2023-08-11 |
mouse |
P Apicella, E Trouche, A Nieoullon, E Legallet, N Dusticie. Motor impairments and neurochemical changes after unilateral 6-hydroxydopamine lesion of the nigrostriatal dopaminergic system in monkeys. Neuroscience. vol 38. issue 3. 1991-02-19. PMID:2125332. |
in all cases, an increase the dihydroxyphenyl-acetic acid to dopamine ratio was detected in the striatum and pallidum suggesting a compensatory increase in dopamine turnover in remaining intact dopaminergic nerve terminals. |
1991-02-19 |
2023-08-11 |
monkey |