| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S P Bagchi, T M Smit. Synaptosomal dopamine from phenylalanine in brain: effects of some dopaminergic agents. Research communications in chemical pathology and pharmacology. vol 26. issue 3. 1980-03-27. PMID:523781. |
synaptosomal dopamine from phenylalanine in brain: effects of some dopaminergic agents. |
1980-03-27 |
2023-08-11 |
rat |
| S P Bagchi, T M Smit. Synaptosomal dopamine from phenylalanine in brain: effects of some dopaminergic agents. Research communications in chemical pathology and pharmacology. vol 26. issue 3. 1980-03-27. PMID:523781. |
this report demonstrates for the first time that the synthesis and release responses to some dopaminergic agents may be elicited from that synaptosomal dopamine which may be formed by the hydroxylations of phenylalanine. |
1980-03-27 |
2023-08-11 |
rat |
| A Yoti. [Brain catecholamines, mental diseases, aging and senile dementia: biochemical and pharmacological aspects]. L'Encephale. vol 5. issue 4. 1980-03-24. PMID:391547. |
since the ca and particularly the dopamine deficiency seems to be a common denominator in depression and in senile mental deterioration, it is suggested that the dopaminergic drugs may serve as useful therapeutic means on one hand and important tools for testing the validity of the above hypotheses on the other. |
1980-03-24 |
2023-08-11 |
Not clear |
| F W Reimherr, D R Wood, P H Wende. An open clinical trial of L-dopa and carbidopa in adults with minimal brain dysfunction. The American journal of psychiatry. vol 137. issue 1. 1980-03-24. PMID:6986093. |
the authors point out that various dopamine agonists have different effects and that the possible potentiation effect is consistent with a dopaminergic hypothesis. |
1980-03-24 |
2023-08-12 |
Not clear |
| U Kraft, H Kraft, K Andrea. [Effect of dopaminergic substances on the antinocifensive action of arecoline]. Acta biologica et medica Germanica. vol 38. issue 4. 1980-03-17. PMID:525142. |
therefore it is concluded that dopamine is not directly involved in the spinal mechanism of the antinocifensive effect of central cholinomimetics, but that only supraspinal influences can be varied by the function of dopaminergic neurons. |
1980-03-17 |
2023-08-11 |
Not clear |
| L Decsi, K Zámbó, J Nagy, E Gác. Atropine stereotypy and its inhibition by intracaudate triperidol in the rat. Polish journal of pharmacology and pharmacy. vol 31. issue 4. 1980-03-17. PMID:574956. |
it is concluded that stereotypy can be evoked also in the case when the striatal dopaminergic tone is normal or even below normal: it is the equilibrium of the striatal cholinergic-dopaminergic systems which must be shifted towards dopamine, which is necessary for the development of this behavioral manifestation. |
1980-03-17 |
2023-08-11 |
rat |
| K F Funk, K H Westerman. Influence of lesion of the median raphe nucleus on motility and dopamine turnover. Polish journal of pharmacology and pharmacy. vol 31. issue 4. 1980-03-17. PMID:574958. |
after unilateral microinjection of dopamine into dopaminergic areas intensity of rotation and dominance of direction are amplified in lesioned animals. |
1980-03-17 |
2023-08-11 |
Not clear |
| S I Zharikov, A D Zharikova, A Iu Budantse. [Effect of beta-phenylethylamine on the dopaminergic system of rat brain]. Neirofiziologiia = Neurophysiology. vol 11. issue 6. 1980-02-28. PMID:514416. |
using a quantitative fluorescence-histochemical analysis the dynamics of changes of the dopamine level in dopaminergic neurons of the nigro-neostriatal and mesolimbic systems of the rat brain was studied during an hour after intraperitoneal injection of beta-phenylethylamine (100 mg/kg). |
1980-02-28 |
2023-08-11 |
rat |
| G A Lopez, F D Romano, V A Aletich, L M Lissuzz. Cyclic adenosine 3':5-monophosphate mediation of the effect of dopamine on renin release by renal cortical slices from sodium-deficient rats: modification by dopaminergic and beta-adrenergic receptor blockade. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 162. issue 3. 1980-02-26. PMID:42078. |
cyclic adenosine 3':5-monophosphate mediation of the effect of dopamine on renin release by renal cortical slices from sodium-deficient rats: modification by dopaminergic and beta-adrenergic receptor blockade. |
1980-02-26 |
2023-08-11 |
rat |
| J L Waddington, T J Cro. Rotational responses to serotonergic and dopaminergic agonists after unilateral dihydroxytryptamine lesions of the medial forebrain bundle: co-operative interactions of serotonin and dopamine in neostriatum. Life sciences. vol 25. issue 15. 1980-02-26. PMID:316093. |
rotational responses to serotonergic and dopaminergic agonists after unilateral dihydroxytryptamine lesions of the medial forebrain bundle: co-operative interactions of serotonin and dopamine in neostriatum. |
1980-02-26 |
2023-08-11 |
Not clear |
| W S Evans, A D Rogol, R M MacLeod, M O Thorne. Dopaminergic mechanisms and luteinizing hormone secretion. I. Acute administration of the dopamine agonist bromocriptine does not inhibit luteinizing hormone release in hyperprolactinemic women. The Journal of clinical endocrinology and metabolism. vol 50. issue 1. 1980-02-26. PMID:7188612. |
since hyperprolactinemia is associated with increased hypothalamic dopamine turnover (which may reflect increased dopaminergic activity), inhibition of gnrh by dopamine in this situation would be maximal. |
1980-02-26 |
2023-08-12 |
Not clear |
| K Andersson, R Schwarcz, K Fux. Compensatory bilateral changes in dopamine turnover after striatal kainate lesion. Nature. vol 283. issue 5742. 1980-02-26. PMID:7188627. |
unilateral pharmacological manipulations result in short-term changes in contralateral dopamine (da) release, and surgical lesions on one side lead to long-term alterations in the firing rate of contralateral dopaminergic neurones. |
1980-02-26 |
2023-08-12 |
Not clear |
| M Filio. Effects of interruption of the nigrostriatal pathway and of dopaminergic agents on the spontaneous activity of globus pallidus neurons in the awake monkey. Brain research. vol 178. issue 2-3. 1980-02-15. PMID:116713. |
two lines of evidence strongly suggest that the bursting pallidal activities are a consequence of the interruption of the nigrostriatal dopaminergic pathway: (1) the percentage of bursting pallidal neurons is proportional to the amount of degeneration in the pars compacta of the ipsilateral substantia nigra; (2) chronic administration of dopamine antagonists, haloperidol and reserpine, reproduces in intact monkeys the bursting activities observed in lesioned animals. |
1980-02-15 |
2023-08-11 |
monkey |
| T Di Paolo, R Carmichael, F Labrie, J P Raynau. Effects of estrogens on the characteristics of [3H]spiroperidol and [3H]RU24213 binding in rat anterior pituitary gland and brain. Molecular and cellular endocrinology. vol 16. issue 2. 1980-02-15. PMID:116893. |
since estrogens have been found to exert a marked inhibitory effect on dopaminergic action at the anterior pituitary and striatal levels in the rat, the effect of estrogen treatment has been studied on the binding characteristics of the dopamine (da) antagonist [3h]spiroperidol and of the new da agonist [3h]n-n-propyl-n-phenylethyl-beta-(3-hydroxyphenyl)ethylamine hydrochloride ([3h]ru24213) in rat striatum, nucleus accumbens + olfactory tubercle, frontal cortex and anterior pituitary gland. |
1980-02-15 |
2023-08-11 |
rat |
| G Langer, E J Sachar, R S Nathan, M A Tabrizi, J M Perel, F S Halper. Dopaminergic factors in human prolactin regulation: a pituitary model for the study of a neuroendocrine system in man. Psychopharmacology. vol 65. issue 2. 1980-02-15. PMID:117485. |
a dose of dopamine in the order of 15-60 microgram/min appeared to match the "loss" of endogenous dopaminergic inhibition due to the antidopaminergic effect of the neuroleptic drug. |
1980-02-15 |
2023-08-11 |
human |
| S Bischoff, B Scatton, J Kor. Dopamine metabolism, spiperone binding and adenylate cyclase activity in the adult rat hippocampus after ingrowth of dopaminergic neurones from embryonic implants. Brain research. vol 179. issue 1. 1980-02-15. PMID:509234. |
dopamine metabolism, spiperone binding and adenylate cyclase activity in the adult rat hippocampus after ingrowth of dopaminergic neurones from embryonic implants. |
1980-02-15 |
2023-08-11 |
rat |
| L L Brown, M H Markman, L I Wolfson, B Dvorkin, C Warner, R Katzma. A direct role of dopamine in the rat subthalamic nucleus and an adjacent intrapeduncular area. Science (New York, N.Y.). vol 206. issue 4425. 1980-01-28. PMID:505015. |
thus, neuronal function in this region is directly affected by dopamine and dopaminergic drugs. |
1980-01-28 |
2023-08-11 |
rat |
| S Dessaigne, A M Scotto, M Guigue. [Lithium modifications of the cataleptogenic properties of various neuroleptic drugs in the rat]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 172. issue 6. 1980-01-24. PMID:40676. |
licl would interfere at enzymatic level with dopaminergic transmission either by inhibiting activity of cerebral adenylcyclase (unique injection) or by inhibiting dopamine synthesis (repeated injections). |
1980-01-24 |
2023-08-11 |
rat |
| J Vardi, S Flechter, Z Oberman, M Allelov, J M Rabey, M Hertzberg, M Streifle. Plasma dopamine beta hydroxylase (D.B.H.) activity in Parkinsonian patients under L-dopa, and 2-bromo-alpha-ergocriptine loading. Journal of neural transmission. vol 46. issue 1. 1980-01-24. PMID:501350. |
the reduced d.b.h.-activity after treatment with 2-bromo-alpha-ergocriptine may be explained by a pronounced antagonistic influence of 2-bromo-alpha-ergocriptine on the presynaptic dopamine receptors, suggesting that presynaptic dopaminergic receptors are involved in parkinson's disease. |
1980-01-24 |
2023-08-11 |
Not clear |
| G Magelund, J Gerlach, D E Case. Neuroleptic-potentiating effect of alpha-methyl-p-tyrosine compared with haloperidol and placebo in a double-blind cross-over trial. Acta psychiatrica Scandinavica. vol 60. issue 2. 1980-01-19. PMID:41413. |
the hypothesis that schizophrenia results from overactive dopaminergic influences suggests that reducing dopamine synthesis may increase the clinical effects of dopamine receptor blocking neuroleptic drugs. |
1980-01-19 |
2023-08-11 |
Not clear |