| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O Kuchel, N T Buu, T Unger, J Genes. Free and conjugated catecholamines in human hypertension. Clinical science and molecular medicine. Supplement. vol 4. 1979-03-24. PMID:282103. |
elevated conjugated dopamine appears to reflect a compensatory activation of the dopaminergic vasodilator pathway in hypertension, the total urinary dopamine excretion an intrinsic deficiency or compensatory increase of a dopamine-modulated natriuretic mechanism. |
1979-03-24 |
2023-08-11 |
human |
| H C Fibiger, S T Maso. The effects of dorsal bundle injections of 6-hydroxydopamine on avoidance responding in rats. British journal of pharmacology. vol 64. issue 4. 1979-03-24. PMID:728687. |
4 a comparison with work by other authors in which both forebrain noradrenaline and dopamine were depleted suggest that the alteration in extinction seen in both studies is a noradrenergic effect, whereas the deficits in acquisition and retention found previously are dopaminergic in origin. |
1979-03-24 |
2023-08-11 |
rat |
| N White, Z Brown, M Yachni. Effects of catecholamine manipulations on three different self-stimulation behaviors. Pharmacology, biochemistry, and behavior. vol 9. issue 5. 1979-03-24. PMID:733849. |
at low doses of pimozide (a dopaminergic blocker) or of fla-57 (a dopamine beta-hydroxylase inhibitor) different effects on rates of responding were observed on each of the three tasks at the two electrode placements, indicating that the rate reductions were not the results of specific performance effects of the drugs. |
1979-03-24 |
2023-08-11 |
rat |
| A M Di Giulio, A Groppetti, F Cattabeni, C L Galli, A Maggi, S Algeri, F Ponzi. Significance of dopamine metabolites in the evaluation of drugs acting on dopaminergic neurons. European journal of pharmacology. vol 52. issue 2. 1979-03-13. PMID:729633. |
significance of dopamine metabolites in the evaluation of drugs acting on dopaminergic neurons. |
1979-03-13 |
2023-08-11 |
rat |
| J W Kebabian, P R Kebabia. Lergotrile and lisuride: in vivo dopaminergic agonists which do not stimulate the presynaptic dopamine autoreceptor. Life sciences. vol 23. issue 22. 1979-02-21. PMID:31541. |
lergotrile and lisuride: in vivo dopaminergic agonists which do not stimulate the presynaptic dopamine autoreceptor. |
1979-02-21 |
2023-08-11 |
Not clear |
| P Taylor, P K Gillman, R Gain. Alpha-methyldopa in schizophrenia. The Journal of clinical psychiatry. vol 39. issue 11. 1979-02-21. PMID:721785. |
the dopamine hypothesis of schizophrenia suggests that there is a functional excess of dopaminergic activity within the brain of schizophrenics. |
1979-02-21 |
2023-08-11 |
Not clear |
| D Eccleston, N Nicolao. The influence of L-tryptophan and monoamine oxidase inhibitors on catecholamine metabolism in rat brain. British journal of pharmacology. vol 64. issue 3. 1979-02-12. PMID:719232. |
the results suggest either a release of dopamine and noradrenaline by 5-hydroxytryptamine, with a compensatory increase in their synthesis, or an increase in the firing of dopaminergic and noradrenergic neurones after l-tryptophan. |
1979-02-12 |
2023-08-11 |
rat |
| L Edvinsson, J E Hardebo, J McCulloch, C Owma. Effects of dopaminergic agonists and antagonists on isolated cerebral blood vessels. Acta physiologica Scandinavica. vol 104. issue 3. 1979-01-26. PMID:716985. |
the vasomotor response of dopamine and dopaminergic agonists was studied in vitro on middle cerebral arteries from cat and pial arteries from humans. |
1979-01-26 |
2023-08-11 |
cat |
| F M Sharabi, J P Long, J G Canno. Hypotensive effect induced by a cyclic dopamine analog, trans-4-methyl-7,8-dihydroxy-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline. Journal of pharmaceutical sciences. vol 67. issue 11. 1979-01-24. PMID:712612. |
this study confirmed the possibility that the decrease in blood pressure and heart rate elicited by the dopamine analog is attributable to an effect on specific dopaminergic receptors. |
1979-01-24 |
2023-08-11 |
rat |
| J C Reubi, P C Emson, T M Jessell, L L Iverse. Effects of GABA, dopamine, and substance P on the release of newly synthesized 3H-5-hydroxytryptamine from rat substantia nigra in vitro. Naunyn-Schmiedeberg's archives of pharmacology. vol 304. issue 3. 1979-01-24. PMID:714184. |
this effect seems to be indirect and is possibly mediated by dopaminergic neurones, since the dopamine antagonist drug alpha-flupenthixol (1 micron) abolished the substance p-evoked release of 5-ht. |
1979-01-24 |
2023-08-11 |
rat |
| J C Reubi, P C Emson, T M Jessell, L L Iverse. Effects of GABA, dopamine, and substance P on the release of newly synthesized 3H-5-hydroxytryptamine from rat substantia nigra in vitro. Naunyn-Schmiedeberg's archives of pharmacology. vol 304. issue 3. 1979-01-24. PMID:714184. |
substance p may, therefore, activate nigral dopaminergic neurones which then release dopamine from their dendrites. |
1979-01-24 |
2023-08-11 |
rat |
| N White, Z Brown, M Yachni. Effects of catecholamine manipulations on three different self-stimulation behaviors. Pharmacology, biochemistry, and behavior. vol 9. issue 3. 1979-01-15. PMID:714976. |
at low doses of pimozide (a dopaminergic blocker) or of fla-57 (a dopamine beta-hydroxylase inhibitor) different effects on rates of responding were observed on each of the 3 tasks at the 2 electrode placements, indicating that the rate reductions were not the results of specific performance effects of the drugs. |
1979-01-15 |
2023-08-11 |
rat |
| P E Setler, H M Sarau, C L Zirkle, H L Saunder. The central effects of a novel dopamine agonist. European journal of pharmacology. vol 50. issue 4. 1978-12-27. PMID:568069. |
a new peripheral dopamine agonist which causes dopaminergic renal vasodilation, was tested for central dopaminergic activity. |
1978-12-27 |
2023-08-11 |
rat |
| B Bioulac, F Fumoux, A Ferron, J D Vincen. Responses of central neurones to piribedil and 2-bromo-alpha-ergocryptine: comparison with dopamine and apomorphine. European journal of pharmacology. vol 51. issue 1. 1978-12-27. PMID:699972. |
their effects were compared with those of dopamine and apomorphine on neurones of the frontal cortex and of the caudate nucleus both of which are rich in dopaminergic terminals. |
1978-12-27 |
2023-08-11 |
Not clear |
| H Beckman. [Psychotropic drugs as tools for clinical research into schizophrenia (author's transl)]. Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete. vol 46. issue 10. 1978-12-20. PMID:29831. |
dopaminergic overstimulation may be elicited by different drugs interacting with the dopamine metabolism e. g. dopamine-beta-hydroxylase inhibition (disulfiram, fusaric acid); monoamine-oxidase-inhibition (phenelzine, tranylcypromine); dopamine release (amphetamine); stimulation of postsynaptic dopamine receptors (bromocriptine, apomorphine). |
1978-12-20 |
2023-08-11 |
human |
| A Cheramy, R Michelot, V Leviel, A Nieoullon, J Glowinski, B Kerdelhu. Effect of the immunoneutralization of substance P in the cat substantia nigra on the release of dopamine from dendrites and terminals of dopaminergic neurons. Brain research. vol 155. issue 2. 1978-12-02. PMID:688024. |
effect of the immunoneutralization of substance p in the cat substantia nigra on the release of dopamine from dendrites and terminals of dopaminergic neurons. |
1978-12-02 |
2023-08-11 |
cat |
| A D Korczy. The pathophysiology of dystonia. Journal of neural transmission. vol 42. issue 3. 1978-11-27. PMID:690631. |
this acute manifestation is not likely to be a simple consequence of reduced dopaminergic activity, because it was never reported to occur following the use of drugs which deplete dopamine stores, like reserpine and tetrabenazine. |
1978-11-27 |
2023-08-11 |
Not clear |
| A Groppetti, M Parenti, F Cattabeni, A Maggi, L De Angelis, M Monduzzi, G Racagn. Dopaminergic receptor activity in substantia nigra in the mechanisms of autoregulation of striatal dopamine release. Advances in biochemical psychopharmacology. vol 19. 1978-11-18. PMID:696464. |
dopaminergic receptor activity in substantia nigra in the mechanisms of autoregulation of striatal dopamine release. |
1978-11-18 |
2023-08-11 |
Not clear |
| D D Mille. Steric aspects of dopaminergic drugs. Federation proceedings. vol 37. issue 10. 1978-10-27. PMID:28250. |
the rotameric forms of dopamine are also important considerations when examining a molecule for dopaminergic agonist activity. |
1978-10-27 |
2023-08-11 |
Not clear |
| J Rotrosen, B M Angrist, S Gershon, M Aronson, P Gruen, E J Sachar, R K Denning, S Matthysse, M Stanley, S Wil. Thiethylperazine; clinical antipsychotic efficacy and correlation with potency in predictive systems. Archives of general psychiatry. vol 35. issue 9. 1978-10-27. PMID:99115. |
a one-to-one relationship between clinical antipsychotic potency and pharmacologic dopaminergic antagonism is implicit in the dopamine hypothesis of neuroleptic action. |
1978-10-27 |
2023-08-11 |
rat |