| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H J Chiel, R J Wurtma. Suppression of amphetamine-induced hypothermia by the neutral amino acid valine. Psychopharmacology communications. vol 2. issue 3. 1977-01-28. PMID:996276. |
because dopaminergic neurons mediate the hypothermic response to amphetamine and because amphetamine's ability to produce hypothermia requires, in part, the release of newly synthesized dopamine, these observed effects of valine pretreatment support the hypothesis that treatments which alter precursor (tyrosine) availability also affect brain catecholamine synthesis. |
1977-01-28 |
2023-08-11 |
rat |
| E A Zeller, B Boshes, J Arbit, M Bieber, E R Blonsky, M Dolkart, S V Huprika. Molecular biology of neurological and psychiatric disorders. I. Effect of parkinsonism, age, sex and L-dopa on platelet monoamine oxidase. Journal of neural transmission. vol 39. issue 1-2. 1976-12-30. PMID:978197. |
dopamine, formed from l-dopa, may thus have a better chance for survival in reaching the dopaminergic receptor. |
1976-12-30 |
2023-08-11 |
human |
| A Simon, E F Van Maane. Dopamine receptors and dopaminergic nerves in the vas deferens of the rat. Archives internationales de pharmacodynamie et de therapie. vol 222. issue 1. 1976-12-30. PMID:984969. |
dopamine receptors and dopaminergic nerves in the vas deferens of the rat. |
1976-12-30 |
2023-08-11 |
rat |
| G Verde, G Oppizzi, G Colussi, G Cremascoli, L Botalla, E E Müller, F Silvestrini, P G Chiodini, A Liuzz. Effect of dopamine infusion on plasma levels of growth hormone in normal subjects and in agromegalic patients. Clinical endocrinology. vol 5. issue 4. 1976-12-03. PMID:971548. |
since dopamine does not cross the blood-brain barrier, these results, although not excluding a site of action at median eminence level, support the thesis that the inhibitory effect of dopaminergic stimulation on gh release in acromegaly possibly involves receptors present on gh-secreting cells. |
1976-12-03 |
2023-08-11 |
human |
| J G Cannon, G J Hathewa. Centrally acting emetics. 10. Rigid dopamine congeners derived from octahydrobenzo[f]quinoline. Journal of medicinal chemistry. vol 19. issue 8. 1976-11-21. PMID:184283. |
in a study of conformational requirements for certain dopaminergic agonist molecules, a series of conformationally predictable dopamine congeners related to cis- and trans-octahydrobenzo[f]quinoline was prepared. |
1976-11-21 |
2023-08-11 |
Not clear |
| H Leblanc, G C Lachelin, S Abu-Fadil, S S Ye. Effects of dopamine infusion on pituitary hormone secretion in humans. The Journal of clinical endocrinology and metabolism. vol 43. issue 3. 1976-11-01. PMID:956350. |
these data indicate that in man a dopaminergic mechanism ixists in the regulation of prl secretion and that dopamine also exerts an inhibitory effect of lh release. |
1976-11-01 |
2023-08-11 |
human |
| T J Crow, E C Johnstone, J F Deakin, A Longde. Dopamine and schizophrenia. Lancet (London, England). vol 2. issue 7985. 1976-10-29. PMID:60635. |
it is argued that the former are more closely related to actions on dopaminergic mechanisms in the "mesolimbic dopamine" system, and the latter to similar actions in the striatum. |
1976-10-29 |
2023-08-11 |
Not clear |
| T J Crow, E C Johnstone, J F Deakin, A Longde. Dopamine and schizophrenia. Lancet (London, England). vol 2. issue 7985. 1976-10-29. PMID:60635. |
although the amphetamine psychosis closely resembles paranoid schizophrenia and may be due to excess dopamine release, clinical, biochemical, and endocrine studies suggest that dopaminergic overactivity is not a necessary concomitant of schizophrenic illnesses. |
1976-10-29 |
2023-08-11 |
Not clear |
| A P Ferk. The inhibitory action of dopamine on the anterior tibialis muscle preparation antagonized by pimozide and chlorpromazine. Archives internationales de pharmacodynamie et de therapie. vol 221. issue 1. 1976-10-20. PMID:962431. |
the phenothiazine derivative, chlorpromazine (cpz, 400 mug/kg) which possesses both alpha and dopaminergic blocking properties significantly reduces the action of dopamine on skeletal muscle. |
1976-10-20 |
2023-08-11 |
cat |
| A P Ferk. The inhibitory action of dopamine on the anterior tibialis muscle preparation antagonized by pimozide and chlorpromazine. Archives internationales de pharmacodynamie et de therapie. vol 221. issue 1. 1976-10-20. PMID:962431. |
however, phentolamine (1 mg/kg), an alpha adrenergic blocker is without effect, possibly indicating that the dopaminergic blocking characteristic of cpz is responsible for decreasing the action of dopamine. |
1976-10-20 |
2023-08-11 |
cat |
| A P Ferk. The inhibitory action of dopamine on the anterior tibialis muscle preparation antagonized by pimozide and chlorpromazine. Archives internationales de pharmacodynamie et de therapie. vol 221. issue 1. 1976-10-20. PMID:962431. |
a more selective dopaminergic blocking agent, pimozide (100 and 200 mug/kg) is an effective antagonist to the paralysis caused by dopamine on the anterior tibialis muscle. |
1976-10-20 |
2023-08-11 |
cat |
| F S Messiha, W Knop. A study of endogenous dopamine metabolism in Gilles de la Tourette's disease. Diseases of the nervous system. vol 37. issue 8. 1976-10-20. PMID:1066216. |
the results suggest that monitering urinary dopamine and 3-methoxytyramine excretion in tourette's disease may predict the clinical response to pharmacotherapy, and that a dopaminergic mechanism may be associated with this type of motor hyperkinesia. |
1976-10-20 |
2023-08-11 |
Not clear |
| K Kuschinsk. Actions of narcotics on brain dopamine metabolism and their relevance for "psychomotor" effects. Arzneimittel-Forschung. vol 26. issue 4. 1976-10-02. PMID:8059. |
in rats, acute doses of morphine decrease the dopaminergic neurotransmission in brain, without blocking postsynaptic dopamine receptors. |
1976-10-02 |
2023-08-11 |
mouse |
| S Korsgaar. Baclofen (Lioresal) in the treatment ofneuroleptic-induced tardive dyskinesia. Acta psychiatrica Scandinavica. vol 54. issue 1. 1976-10-02. PMID:782159. |
in tardive dyskinesia is found dopaminergic hypersensitivity, and baclofen is supposed to exert its action by inhibiting the dopamine activity. |
1976-10-02 |
2023-08-11 |
Not clear |
| M Smialowsk. The influence of 1,3-dimethyl-5-adamantanamine (D-145) on catecholaminergic neurons of the rat brain, Histofluorescence studies. Polish journal of pharmacology and pharmacy. vol 28. issue 3. 1976-10-02. PMID:951308. |
a blockade of dopamine (da) receptors with spiperone (spiro, 2 mg/kg, 5 min before d-145) abolished the d-145 effect in pvh, thus indicating an indirect effect of d-145 on pvh, via a dopaminergic system. |
1976-10-02 |
2023-08-11 |
rat |
| B Scatton, J Glowinski, L Julo. Dopamine metabolism in the mesolimbic and mesocortical dopaminergic systems after single or repeated administrations of neuroleptics. Brain research. vol 109. issue 1. 1976-08-23. PMID:6117. |
dopamine metabolism in the mesolimbic and mesocortical dopaminergic systems after single or repeated administrations of neuroleptics. |
1976-08-23 |
2023-08-11 |
Not clear |
| B Cox, P Loma. Brain amines and spontaneous epileptic seizures in the Mongolian gerbil. Pharmacology, biochemistry, and behavior. vol 4. issue 3. 1976-08-23. PMID:180544. |
increasing central norepinephrine and dopamine levels significantly reduced the severity of the seizures and the importance of dopamine was further demonstrated by the protection from seizures after administration of the dopaminergic agonist apomorphine. |
1976-08-23 |
2023-08-11 |
Not clear |
| L C Murrin, R H Rot. Dopaminergic neurons: effects of electrical stimulation on dopamine biosynthesis. Molecular pharmacology. vol 12. issue 3. 1976-08-23. PMID:934059. |
dopaminergic neurons: effects of electrical stimulation on dopamine biosynthesis. |
1976-08-23 |
2023-08-11 |
Not clear |
| H Ladinsky, S Consolo, S Bianchi, A Jor. Increase in striatal acetylcholine by picrotoxin in the rat: evidence for a gabergic-dopaminergic-cholinergic link. Brain research. vol 108. issue 2. 1976-08-23. PMID:945112. |
the results are interpreted as follows: picrotoxin released dopamine through disinhibition of the dopaminergic neurons as a result of blockade of gabergic receptors. |
1976-08-23 |
2023-08-11 |
rat |
| J S Kizer, M Palkovits, M J Brownstei. The projections of the A8, A9 and A10 dopaminergic cell bodies: evidence for a nigral-hypothalamic-median eminence dopaminergic pathway. Brain research. vol 108. issue 2. 1976-08-23. PMID:1276901. |
using the microdissection method of palkovits and a sensitive microassay for dopamine (da) and norepinephrine (ne), the cns projections of the nigral a8, a9 and a10 dopaminergic cell bodies have been determined in rat brain. |
1976-08-23 |
2023-08-11 |
rat |