| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Kyle Krady, Anirban Basu, Colleen M Allen, Yuping Xu, Kathryn F LaNoue, Thomas W Gardner, Steven W Leviso. Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy. Diabetes. vol 54. issue 5. 2005-07-05. PMID:15855346. |
minocycline represses diabetes-induced inflammatory cytokine production, reduces the release of cytotoxins from activated microglia, and significantly reduces measurable caspase-3 activity within the retina. |
2005-07-05 |
2023-08-12 |
Not clear |
| Stacey Hose, J Samuel Zigler, Debasish Sinh. A novel rat model to study the functions of macrophages during normal development and pathophysiology of the eye. Immunology letters. vol 96. issue 2. 2005-06-10. PMID:15585337. |
it has also been postulated that macrophages around the developing lens likely migrate into the neural retina and differentiate into microglia after completion of their role as debris removers. |
2005-06-10 |
2023-08-12 |
rat |
| G M Sarra, F G Sarra, F C Schlichtenbrede, P Trittibach, S Estermann, E Tsiroukis, R R Ali, P J Luthert, M B Reiche. Effect of steroidal and non-steroidal drugs on the microglia activation pattern and the course of degeneration in the retinal degeneration slow mouse. Ophthalmic research. vol 37. issue 2. 2005-06-07. PMID:15746562. |
in this study we wanted to test the impact of the most commonly used anti-inflammatory drugs (acetylsalicylate and prednisolone) on the microglia activation pattern, the rate of caspase-3-dependent photoreceptor apoptosis and the course of the degeneration in the retinal degeneration slow (rds) mouse retina. |
2005-06-07 |
2023-08-12 |
mouse |
| S-T Chen, J-I Chuang, C-L Cheng, L-J Hsu, N-S Chan. Light-induced retinal damage involves tyrosine 33 phosphorylation, mitochondrial and nuclear translocation of WW domain-containing oxidoreductase in vivo. Neuroscience. vol 130. issue 2. 2005-04-25. PMID:15664696. |
prolonged exposure of mature rats to constant, low-intensity light (500 lux) for 1-2 months resulted in substantial death of photoreceptors and the presence of activated microglia, astrocytes and muller glial in the outer retina. |
2005-04-25 |
2023-08-12 |
mouse |
| Debatri Banerjee, Andrew D Dic. Blocking CD200-CD200 receptor axis augments NOS-2 expression and aggravates experimental autoimmune uveoretinitis in Lewis rats. Ocular immunology and inflammation. vol 12. issue 2. 2005-01-25. PMID:15512981. |
tissue expression of cd200 generates inhibitory or down-regulatory signals to macrophages and microglia within cns and retina. |
2005-01-25 |
2023-08-12 |
rat |
| E J Kuiper, A N Witmer, I Klaassen, N Oliver, R Goldschmeding, R O Schlingeman. Differential expression of connective tissue growth factor in microglia and pericytes in the human diabetic retina. The British journal of ophthalmology. vol 88. issue 8. 2004-08-26. PMID:15258030. |
differential expression of connective tissue growth factor in microglia and pericytes in the human diabetic retina. |
2004-08-26 |
2023-08-12 |
human |
| Dale S Gregerson, Thien N Sam, Scott W McPherso. The antigen-presenting activity of fresh, adult parenchymal microglia and perivascular cells from retina. Journal of immunology (Baltimore, Md. : 1950). vol 172. issue 11. 2004-08-06. PMID:15153473. |
the antigen-presenting activity of fresh, adult parenchymal microglia and perivascular cells from retina. |
2004-08-06 |
2023-08-12 |
Not clear |
| Erik Schuetz, Solon Thano. Neuro-glial interactions in the adult rat retina after reaxotomy of ganglion cells: examination of neuron survival and phagocytic microglia using fluorescent tracers. Brain research bulletin. vol 62. issue 5. 2004-07-09. PMID:15168904. |
neuro-glial interactions in the adult rat retina after reaxotomy of ganglion cells: examination of neuron survival and phagocytic microglia using fluorescent tracers. |
2004-07-09 |
2023-08-12 |
rat |
| Karl Engelsberg, Berndt Ehinger, Johan Wassélius, Kjell Johansso. Apoptotic cell death and microglial cell responses in cultured rat retina. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. vol 242. issue 3. 2004-06-30. PMID:14745560. |
apoptotic cell death and microglial cell responses in cultured rat retina. |
2004-06-30 |
2023-08-12 |
rat |
| Ana Sánchez-López, Miguel A Cuadros, Ruth Calvente, Mohamed Tassi, José L Marín-Teva, Julio Navascué. Radial migration of developing microglial cells in quail retina: a confocal microscopy study. Glia. vol 46. issue 3. 2004-05-28. PMID:15048849. |
the cellular mechanism of tangential migration of microglia has been described in the quail retina but the mechanism of their radial migration has not been studied. |
2004-05-28 |
2023-08-12 |
Not clear |
| Ana Sánchez-López, Miguel A Cuadros, Ruth Calvente, Mohamed Tassi, José L Marín-Teva, Julio Navascué. Radial migration of developing microglial cells in quail retina: a confocal microscopy study. Glia. vol 46. issue 3. 2004-05-28. PMID:15048849. |
when microglial cell radial migration ends, tenascin immunostaining is no longer present in the retina. |
2004-05-28 |
2023-08-12 |
Not clear |
| Cheng Zhang, Mark O M Ts. Characterization of activated retinal microglia following optic axotomy. Journal of neuroscience research. vol 73. issue 6. 2003-10-14. PMID:12949910. |
microglia are prominently involved in neural degenerative diseases of the cns and the retina. |
2003-10-14 |
2023-08-12 |
rat |
| Andrew D Dick, Debra Carter, Morag Robertson, Cathryn Broderick, Edward Hughes, John V Forrester, Janet Liversidg. Control of myeloid activity during retinal inflammation. Journal of leukocyte biology. vol 74. issue 2. 2003-09-09. PMID:12885931. |
success is dependent on response of the resident myeloid-cell populations [microglia (mg)] to activation signals, commonly cytokines, and the control of infiltrating macrophage activation during inflammation, both of which appear highly programmed in normal and inflamed retina. |
2003-09-09 |
2023-08-12 |
mouse |
| E Raibon, Y Sauvé, D A Carter, F Gaillar. Microglial changes accompanying the promotion of retinal ganglion cell axonal regeneration into peripheral nerve grafts. Journal of neurocytology. vol 31. issue 1. 2003-05-27. PMID:12652088. |
intravitreal injection of the microglia inhibitor tuftsin 1-3 leads to an increase in retinal ganglion cell axonal regeneration into peripheral nerve grafts and a decrease in phagocytic cells in the retina. |
2003-05-27 |
2023-08-12 |
rat |
| E Raibon, Y Sauvé, D A Carter, F Gaillar. Microglial changes accompanying the promotion of retinal ganglion cell axonal regeneration into peripheral nerve grafts. Journal of neurocytology. vol 31. issue 1. 2003-05-27. PMID:12652088. |
preservation within the retina of a higher proportion of resting over active form of microglia, and not the prevention of microglial proliferation per se, may be a crucial factor in allowing additional retinal ganglion cell axons to regenerate into peripheral nerve grafts. |
2003-05-27 |
2023-08-12 |
rat |
| D A Carter, A D Dic. Lipopolysaccharide/interferon-gamma and not transforming growth factor beta inhibits retinal microglial migration from retinal explant. The British journal of ophthalmology. vol 87. issue 4. 2003-05-23. PMID:12642315. |
/aims: the retina possesses a rich network of cd45(+) positive myeloid derived cells that both surround inner retinal vessels and lie within the retina (microglia). |
2003-05-23 |
2023-08-12 |
human |
| Edward H Hughes, Frank C Schlichtenbrede, Conor C Murphy, Gian-Marco Sarra, Philip J Luthert, Robin R Ali, Andrew D Dic. Generation of activated sialoadhesin-positive microglia during retinal degeneration. Investigative ophthalmology & visual science. vol 44. issue 5. 2003-05-19. PMID:12714665. |
the retina contains a rich network of myeloid-derived cells (microglia) within the retinal parenchyma and surrounding vessels. |
2003-05-19 |
2023-08-12 |
mouse |
| Ling Chen, Peizeng Yang, Aize Kijlstr. Distribution, markers, and functions of retinal microglia. Ocular immunology and inflammation. vol 10. issue 1. 2003-02-04. PMID:12461701. |
retinal microglia originate from hemopoietic cells and invade the retina from the retinal margin and the optic disc, most likely via the blood vessels of the ciliary body and iris, and the retinal vasculature, respectively. |
2003-02-04 |
2023-08-12 |
mouse |
| Ling Chen, Peizeng Yang, Aize Kijlstr. Distribution, markers, and functions of retinal microglia. Ocular immunology and inflammation. vol 10. issue 1. 2003-02-04. PMID:12461701. |
they differentiate into ramified parenchymal microglia in the adult retina. |
2003-02-04 |
2023-08-12 |
mouse |
| Ling Chen, Peizeng Yang, Aize Kijlstr. Distribution, markers, and functions of retinal microglia. Ocular immunology and inflammation. vol 10. issue 1. 2003-02-04. PMID:12461701. |
microglia are distributed in the outer plexiform layer (opl), outer nuclear layer (onl), inner plexiform layer (ipl), ganglion cell layer (gcl), and nerve fiber layer (nfl) of the primate retina. |
2003-02-04 |
2023-08-12 |
mouse |