| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Manabu Sasahara, Atsushi Otani, Akio Oishi, Hiroshi Kojima, Yuko Yodoi, Takanori Kameda, Hajime Nakamura, Nagahisa Yoshimur. Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration. The American journal of pathology. vol 172. issue 6. 2008-07-08. PMID:18483210. |
bm-derived cells were recruited to the degenerating retina where they differentiated into microglia and subsequently localized to the degenerating vessels and neurons. |
2008-07-08 |
2023-08-12 |
Not clear |
| Manabu Sasahara, Atsushi Otani, Akio Oishi, Hiroshi Kojima, Yuko Yodoi, Takanori Kameda, Hajime Nakamura, Nagahisa Yoshimur. Activation of bone marrow-derived microglia promotes photoreceptor survival in inherited retinal degeneration. The American journal of pathology. vol 172. issue 6. 2008-07-08. PMID:18483210. |
inhibition of stromal-derived factor-1 in the retina reduced the number of bm-derived microglia and accelerated the rate of neurovascular degeneration. |
2008-07-08 |
2023-08-12 |
Not clear |
| Ana M Santos, Ruth Calvente, Mohamed Tassi, Maria-Carmen Carrasco, David Martín-Oliva, José L Marín-Teva, Julio Navascués, Miguel A Cuadro. Embryonic and postnatal development of microglial cells in the mouse retina. The Journal of comparative neurology. vol 506. issue 2. 2008-02-29. PMID:18022954. |
the mature topographical distribution pattern of microglia emerged during postnatal development of the retina, apparently by radial migration of microglial cells from the vitreal surface in a vitreal-to-scleral direction. |
2008-02-29 |
2023-08-12 |
mouse |
| Heping Xu, Mei Chen, Ayyakkannu Manivannan, Noemi Lois, John V Forreste. Age-dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice. Aging cell. vol 7. issue 1. 2008-02-25. PMID:17988243. |
our observation suggests that perivascular and subretinal microglia are the main cells producing lipofuscin in normal aged mouse retina and are responsible for in vivo fundus af. |
2008-02-25 |
2023-08-12 |
mouse |
| Karin Weigelt, Wolfgang Ernst, Yana Walczak, Stefanie Ebert, Thomas Loenhardt, Maja Klug, Michael Rehli, Bernhard H F Weber, Thomas Langman. Dap12 expression in activated microglia from retinoschisin-deficient retina and its PU.1-dependent promoter regulation. Journal of leukocyte biology. vol 82. issue 6. 2008-01-23. PMID:17827340. |
dap12 expression in activated microglia from retinoschisin-deficient retina and its pu.1-dependent promoter regulation. |
2008-01-23 |
2023-08-12 |
mouse |
| Ai Ling Wang, Zhengbin Li, Ming Yuan, Albert C H Yu, Xiu'An Zhu, Mark O M Ts. Sinomenine inhibits activation of rat retinal microglia induced by advanced glycation end products. International immunopharmacology. vol 7. issue 12. 2008-01-10. PMID:17920532. |
diabetic retinopathy involves an inflammatory response in the retina characterized by an increase in inflammatory cytokines and activation of microglia. |
2008-01-10 |
2023-08-12 |
rat |
| Ai Ling Wang, Zhengbin Li, Ming Yuan, Albert C H Yu, Xiu'An Zhu, Mark O M Ts. Sinomenine inhibits activation of rat retinal microglia induced by advanced glycation end products. International immunopharmacology. vol 7. issue 12. 2008-01-10. PMID:17920532. |
the degree of microglia activation may influence the extent of retina injury following an inflammatory stimulus. |
2008-01-10 |
2023-08-12 |
rat |
| Jing Chen, Kip M Connor, Lois E H Smit. Overstaying their welcome: defective CX3CR1 microglia eyed in macular degeneration. The Journal of clinical investigation. vol 117. issue 10. 2007-11-27. PMID:17909623. |
in this issue of the jci, the study by combadière and colleagues shows that cx3c chemokine receptor 1-deficient (cx3cr1-deficient) mice have abnormal microglia that accumulate beneath the retina and contribute to the progression of amd. |
2007-11-27 |
2023-08-12 |
mouse |
| Lisa Kercher, Cynthia Favara, James F Striebel, Rachel LaCasse, Bruce Chesebr. Prion protein expression differences in microglia and astroglia influence scrapie-induced neurodegeneration in the retina and brain of transgenic mice. Journal of virology. vol 81. issue 19. 2007-11-06. PMID:17652390. |
prion protein expression differences in microglia and astroglia influence scrapie-induced neurodegeneration in the retina and brain of transgenic mice. |
2007-11-06 |
2023-08-12 |
mouse |
| Ana Rita Alvaro, Joana Rosmaninho-Salgado, Ana Raquel Santiago, João Martins, Célia Aveleira, Paulo F Santos, Tiago Pereira, Denisa Gouveia, Ana Luísa Carvalho, Eric Grouzmann, António Francisco Ambrósio, Cláudia Cavada. NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells. Neurochemistry international. vol 50. issue 5. 2007-10-18. PMID:17353067. |
in this work, using different rat retina in vitro models (whole retina, retinal cells in culture, microglial cell cultures, rat müller cell line and retina endothelial cell line), we demonstrated that npy staining is present in the retina in different cell types: neurons, macroglial, microglial and endothelial cells. |
2007-10-18 |
2023-08-12 |
rat |
| Heping Xu, Mei Chen, Eric J Mayer, John V Forrester, Andrew D Dic. Turnover of resident retinal microglia in the normal adult mouse. Glia. vol 55. issue 11. 2007-09-18. PMID:17600341. |
the retina contains two distinct populations of monocyte-derived cells: perivascular cells (macrophages) and parenchymal cells (microglia), important in homeostasis, neuroinflammation, degeneration, and injury. |
2007-09-18 |
2023-08-12 |
mouse |
| Thomas Langman. Microglia activation in retinal degeneration. Journal of leukocyte biology. vol 81. issue 6. 2007-09-17. PMID:17405851. |
microglia cells are phagocytic sentinels in the cns and in the retina required for neuronal homeostasis and innate immune defense. |
2007-09-17 |
2023-08-12 |
Not clear |
| Thomas Langman. Microglia activation in retinal degeneration. Journal of leukocyte biology. vol 81. issue 6. 2007-09-17. PMID:17405851. |
endogenous triggers alert microglia cells rapidly in the degenerating retina, leading to local proliferation, migration, enhanced phagocytosis, and secretion of cytokines, chemokines, and neurotoxins. |
2007-09-17 |
2023-08-12 |
Not clear |
| Thomas Langman. Microglia activation in retinal degeneration. Journal of leukocyte biology. vol 81. issue 6. 2007-09-17. PMID:17405851. |
this review summarizes the developmental and immune surveillance functions of microglia in the healthy retina and discusses early signaling events and transcriptional networks of microglia activation in retinal degeneration. |
2007-09-17 |
2023-08-12 |
Not clear |
| D M Inman, P J Horne. Reactive nonproliferative gliosis predominates in a chronic mouse model of glaucoma. Glia. vol 55. issue 9. 2007-07-25. PMID:17457855. |
astrocyte and müller glia populations within dba/2 retina upregulated glial fibrillary acidic protein mrna and protein compared with c57bl/6; microglial cell number increased twofold from 4 to 10 months. |
2007-07-25 |
2023-08-12 |
mouse |
| Ai Ling Wang, Albert C H Yu, Qi Hua He, Xiu'An Zhu, Mark O M Ts. AGEs mediated expression and secretion of TNF alpha in rat retinal microglia. Experimental eye research. vol 84. issue 5. 2007-07-11. PMID:17359975. |
diabetic retinopathy induces an inflammatory response in the retina characterized by an increase in inflammatory cytokines and the activation of microglia. |
2007-07-11 |
2023-08-12 |
rat |
| Ai Ling Wang, Albert C H Yu, Qi Hua He, Xiu'An Zhu, Mark O M Ts. AGEs mediated expression and secretion of TNF alpha in rat retinal microglia. Experimental eye research. vol 84. issue 5. 2007-07-11. PMID:17359975. |
the degree of microglia activation may influence the extent of retina injury following retinal metabolic stress. |
2007-07-11 |
2023-08-12 |
rat |
| Paloma Sobrado-Calvo, Manuel Vidal-Sanz, María P Villegas-Pére. Rat retinal microglial cells under normal conditions, after optic nerve section, and after optic nerve section and intravitreal injection of trophic factors or macrophage inhibitory factor. The Journal of comparative neurology. vol 501. issue 6. 2007-04-26. PMID:17311318. |
left on section induces microglial activation in the ipsilateral and contralateral retina as manifested by stronger staining intensity in both retinas and increased microglial cell densities in the nfl, ipl, and gcl of the ipsilateral retina. |
2007-04-26 |
2023-08-12 |
rat |
| Paloma Sobrado-Calvo, Manuel Vidal-Sanz, María P Villegas-Pére. Rat retinal microglial cells under normal conditions, after optic nerve section, and after optic nerve section and intravitreal injection of trophic factors or macrophage inhibitory factor. The Journal of comparative neurology. vol 501. issue 6. 2007-04-26. PMID:17311318. |
left on section followed by left eye puncture or intravitreal injection increases microglial cell density in both retinas and induces changes in the microglial cells of the ipsilateral retina that vary depending on the substance injected: bdnf injections delay microglial activation, possibly through retinal ganglion cell neuroprotection, whereas nt3 partially inhibits microglial activation in the nfl; mif injections have no clear effects on microglial activation. |
2007-04-26 |
2023-08-12 |
rat |
| Matthew R Ritter, Eyal Banin, Stacey K Moreno, Edith Aguilar, Michael I Dorrell, Martin Friedlande. Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy. The Journal of clinical investigation. vol 116. issue 12. 2007-01-22. PMID:17111048. |
using a model of oxygen-induced retinopathy, we demonstrate that a population of adult bm-derived myeloid progenitor cells migrated to avascular regions of the retina, differentiated into microglia, and facilitated normalization of the vasculature. |
2007-01-22 |
2023-08-12 |
Not clear |