| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanying Miao, Guo-Li Zhao, Shuo Cheng, Zhongfeng Wang, Xiong-Li Yan. Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma. Progress in retinal and eye research. vol 93. 2023-02-03. PMID:36736070. |
elevated iop activates microglia, and following morphological and functional changes, these cells, as resident immune cells in the retina, show adaptive immune responses, including an enhanced release of pro-inflammatory factors (tumor neurosis factor-α, interleukins, etc.). |
2023-02-03 |
2023-08-14 |
Not clear |
| Valeria Chichagova, Maria Georgiou, Madeleine Carter, Birthe Dorgau, Gerrit Hilgen, Joseph Collin, Rachel Queen, Git Chung, Jila Ajeian, Marina Moya-Molina, Stefan Kustermann, Francois Pognan, Philip Hewitt, Michael Schmitt, Evelyne Sernagor, Lyle Armstrong, Majlinda Lak. Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids. Journal of cellular and molecular medicine. 2023-01-16. PMID:36644817. |
microglia are the primary resident immune cells in the retina. |
2023-01-16 |
2023-08-14 |
human |
| Megan Goyal, Andrea S Bordt, Jay Neitz, David W Marsha. Trogocytosis of neurons and glial cells by microglia in a healthy adult macaque retina. Scientific reports. vol 13. issue 1. 2023-01-12. PMID:36635325. |
trogocytosis of neurons and glial cells by microglia in a healthy adult macaque retina. |
2023-01-12 |
2023-08-14 |
mouse |
| Megan Goyal, Andrea S Bordt, Jay Neitz, David W Marsha. Trogocytosis of neurons and glial cells by microglia in a healthy adult macaque retina. Scientific reports. vol 13. issue 1. 2023-01-12. PMID:36635325. |
here we report that microglia in the adult macaque retina also engulf pieces of neurons and glial cells, but not at sites of synapses. |
2023-01-12 |
2023-08-14 |
mouse |
| Megan Goyal, Andrea S Bordt, Jay Neitz, David W Marsha. Trogocytosis of neurons and glial cells by microglia in a healthy adult macaque retina. Scientific reports. vol 13. issue 1. 2023-01-12. PMID:36635325. |
we analyzed microglia in a volume of serial, ultrathin sections of central macaque retina in which many neurons that ramify in the inner plexiform layer (ipl) had been reconstructed previously. |
2023-01-12 |
2023-08-14 |
mouse |
| Ming-Hui Sun, Kuan-Jen Chen, Chi-Chin Sun, Rong-Kung Tsa. Protective Effect of Pioglitazone on Retinal Ganglion Cells in an Experimental Mouse Model of Ischemic Optic Neuropathy. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36613856. |
furthermore, microglial cell infiltration in the retina (group 1: 2.0 ± 2.6 cells/field; group 2: 15.6 ± 3.5 cells/field; and group 3: 14.8 ± 7.5 cells/field) and retinal thinning (group 1: 6.7 ± 5.7 μm; group 2: 12.8 ± 6.1 μm; and group 3: 15.8 ± 5.8 μm) were also lower in group 1 than in the other two groups. |
2023-01-08 |
2023-08-14 |
mouse |
| Kjell Johansson, Camilla Mohli. Microglia in Cultured Porcine Retina: Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36614320. |
microglia in cultured porcine retina: qualitative immunohistochemical analyses of reactive microglia in the outer retina. |
2023-01-08 |
2023-08-14 |
Not clear |
| Kjell Johansson, Camilla Mohli. Microglia in Cultured Porcine Retina: Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36614320. |
in this immunohistochemical study, we have begun to analyze the transition of subsets of reactive microglia which are known to localize close to the outer plexiform layer (opl) in degenerating in vivo and in vitro retina. |
2023-01-08 |
2023-08-14 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology. vol 13. 2022-12-16. PMID:36524119. |
more than meets the eye: the role of microglia in healthy and diseased retina. |
2022-12-16 |
2023-08-14 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology. vol 13. 2022-12-16. PMID:36524119. |
while most knowledge about microglia comes from brain studies, some mechanisms have been confirmed for microglia cells in the retina, the light-sensing compartment of the eye responsible for initial processing of visual information. |
2022-12-16 |
2023-08-14 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology. vol 13. 2022-12-16. PMID:36524119. |
however, several key pieces of this puzzle are still unaccounted for, as the characterization of retinal microglia has long been hindered by the reduced population size within the retina as well as the previous lack of technologies enabling single-cell analyses. |
2022-12-16 |
2023-08-14 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology. vol 13. 2022-12-16. PMID:36524119. |
thus, studying the roles and signatures adopted specifically by microglia in the retina has become increasingly important. |
2022-12-16 |
2023-08-14 |
Not clear |
| Kaira A Church, Derek Rodriguez, Difernando Vanegas, Irene L Gutierrez, Sandra M Cardona, José L M Madrigal, Tejbeer Kaur, Astrid E Cardon. Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. Journal of neuroinflammation. vol 19. issue 1. 2022-12-14. PMID:36517889. |
models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. |
2022-12-14 |
2023-08-14 |
Not clear |
| Kaira A Church, Derek Rodriguez, Difernando Vanegas, Irene L Gutierrez, Sandra M Cardona, José L M Madrigal, Tejbeer Kaur, Astrid E Cardon. Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. Journal of neuroinflammation. vol 19. issue 1. 2022-12-14. PMID:36517889. |
microglia, the resident phagocytes of the retina, are believed to influence the development of retinopathy, but their exact contributions to vascular integrity and neuronal loss are unknown. |
2022-12-14 |
2023-08-14 |
Not clear |
| Kaira A Church, Derek Rodriguez, Difernando Vanegas, Irene L Gutierrez, Sandra M Cardona, José L M Madrigal, Tejbeer Kaur, Astrid E Cardon. Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. Journal of neuroinflammation. vol 19. issue 1. 2022-12-14. PMID:36517889. |
therefore, utilizing two models of microglia depletion, we aimed to deplete and repopulate microglia to clarify the contribution of microglia to neuronal loss and vascular damage in the diabetic retina in an stz-induced model of hyperglycemia. |
2022-12-14 |
2023-08-14 |
Not clear |
| Siva Prasad Panda, P Hemachandra Reddy, Uma Sankar Gorla, Dsnbk Prasant. Neuroinflammation and neovascularization in diabetic eye diseases (DEDs): identification of potential pharmacotherapeutic targets. Molecular biology reports. 2022-12-13. PMID:36513866. |
microglia in the retina of the optic nerve head are responsible for causing inflammation, discomfort, and neurodegeneration. |
2022-12-13 |
2023-08-14 |
Not clear |
| Sienna S Drake, Marc Charabati, Tristan Simas, Yu Kang T Xu, Etienne J P Maes, Shan Shan Shi, Jack Antel, Alexandre Prat, Barbara Morquette, Alyson E Fournie. 3-Dimensional Immunostaining and Automated Deep-Learning Based Analysis of Nerve Degeneration. International journal of molecular sciences. vol 23. issue 23. 2022-12-11. PMID:36499143. |
it contains axons from the retinal ganglion cells (rgcs) that reside in the retina, myelin forming oligodendrocytes and resident microglia and astrocytes. |
2022-12-11 |
2023-08-14 |
mouse |
| Bingqiao Shen, Huan Yu, Mingui Zhang, Junjue Chen, Yang Zhang, Shushu Xu, Ruiqi Han, Shouyue Huang, Ping Huang, Yisheng Zhon. Establishment of a minimally invasive distal traumatic optic neuropathy model in mice to investigate cascade reactions of retinal glial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 1. 2022-12-05. PMID:36468758. |
immunofluorescence, western blotting, qpcr experiments were conducted to investigate the loss of rgcs and activation or inactivation of microglia, astrocytes and müller glial cells in the retina from the first week to the fourth week after modeling. |
2022-12-05 |
2023-08-14 |
mouse |
| Paul-Alexandre Déchelle-Marquet, Xavier Guillonneau, Florian Sennlaub, Cécile Delarass. P2X7-dependent immune pathways in retinal diseases. Neuropharmacology. 2022-11-13. PMID:36372269. |
in the eye, p2x7 is expressed by resident microglia and immune cells that infiltrate the retina in disease such as age-related macular degeneration (amd), a degenerative retinal disease, and uveitis, an inflammatory eye disease. |
2022-11-13 |
2023-08-14 |
Not clear |
| Bright Asare-Bediako, Yvonne Adu-Agyeiwaah, Antonio Abad, Sergio Li Calzi, Jason L Floyd, Ram Prasad, Mariana DuPont, Richmond Asare-Bediako, Xose R Bustelo, Maria B Gran. Hematopoietic Cells Influence Vascular Development in the Retina. Cells. vol 11. issue 20. 2022-10-27. PMID:36291075. |
by flow cytometry and immunohistochemistry, we show that hematopoietic cells are present in the retina as early as p0, and include microglia, monocytes and macs. |
2022-10-27 |
2023-08-14 |
Not clear |