| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Myrcea A de S Tilger, Renan B Gaiardo, Suzete M Cerutt. Inactivation of the dorsal CA1 hippocampus impairs the consolidation of discriminative avoidance memory by modulating the intrinsic and extrinsic hippocampal circuitry. Journal of chemical neuroanatomy. 2022-12-10. PMID:36496001. |
differential camp-response-element-binding protein 1 (creb-1) expression in the dorsal and ventral ca1 and ca3 of the hippocampus (dca1, dca3, vca1, and vca3), dorsal dentate gyrus (ddg), and infralimbic (il) and prelimbic (prl) regions of the medial prefrontal cortex was also assessed to investigate the molecular changes associated with the consolidation or retrieval of episodic-like memory and anxiety. |
2022-12-10 |
2023-08-14 |
rat |
| Sebastiaan Moonen, Marta J Koper, Evelien Van Schoor, Jolien M Schaeverbeke, Rik Vandenberghe, Christine A F von Arnim, Thomas Tousseyn, Bart De Strooper, Dietmar Rudolf Tha. Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons. Acta neuropathologica. 2022-12-09. PMID:36481964. |
cleaved gsdmd was detected in microglia, but also in astrocytes and in few pyramidal neurons in the first sector of the cornu ammonis (ca1) of the hippocampus and the temporal cortex of brodmann area 36. |
2022-12-09 |
2023-08-14 |
human |
| E De Felice, E Gonçalves de Andrade, M T Golia, F González Ibáñez, M Khakpour, M A Di Castro, S Garofalo, E Di Pietro, C Benatti, N Brunello, F Tascedda, B Kaminska, C Limatola, D Ragozzino, M E Tremblay, S Alboni, L Magg. Microglial diversity along the hippocampal longitudinal axis impacts synaptic plasticity in adult male mice under homeostatic conditions. Journal of neuroinflammation. vol 19. issue 1. 2022-12-09. PMID:36482444. |
we characterized in depth the features of microglia in the two hippocampal poles and investigated their contribution to ca1 plasticity under physiological conditions. |
2022-12-09 |
2023-08-14 |
mouse |
| Alexander Maltsev, Matvey Roshchin, Ilya Bezprozvanny, Ivan Smirnov, Olga Vlasova, Pavel Balaban, Anastasia Borodinov. Bidirectional regulation by "star forces": Ionotropic astrocyte's optical stimulation suppresses synaptic plasticity, metabotropic one strikes back. Hippocampus. 2022-12-09. PMID:36484471. |
in electrophysiological experiments, we observed a depression of basal field excitatory postsynaptic potentials (fepsps) in the ca1 hippocampal layer following light stimulation of astrocytic chr2. |
2022-12-09 |
2023-08-14 |
Not clear |
| Claire A Symanski, John H Bladon, Emi T Kullberg, Paul Miller, Shantanu P Jadha. Rhythmic coordination and ensemble dynamics in the hippocampal-prefrontal network during odor-place associative memory and decision making. eLife. vol 11. 2022-12-08. PMID:36480255. |
in order to investigate the mechanisms of such coordination, we monitored activity in hippocampus (ca1), pfc, and olfactory bulb (ob) in rats performing an odor-place associative memory guided decision task on a t-maze. |
2022-12-08 |
2023-08-14 |
rat |
| David A Cinalli, Sarah J Cohen, Mariah Calubag, Goksu Oz, Lylybell Zhou, Robert W Stackma. DREADD-inactivation of dorsal CA1 pyramidal neurons in mice impairs retrieval of object and spatial memories. Hippocampus. 2022-12-05. PMID:36468186. |
for example, muscimol-induced depression of ca1 neuronal activity in the dorsal hippocampus impairs the encoding, consolidation, and retrieval of nonspatial object memory in mice. |
2022-12-05 |
2023-08-14 |
mouse |
| David A Cinalli, Sarah J Cohen, Mariah Calubag, Goksu Oz, Lylybell Zhou, Robert W Stackma. DREADD-inactivation of dorsal CA1 pyramidal neurons in mice impairs retrieval of object and spatial memories. Hippocampus. 2022-12-05. PMID:36468186. |
these results suggest that a common subset of ca1 neurons (i.e., those expressing hm4di receptors) in mouse hippocampus contributed to the retrieval of long-term memory for nonspatial and spatial information. |
2022-12-05 |
2023-08-14 |
mouse |
| Janaína Zang, Anna Clara Machado Colucci, Isadora D'Ávila Tassinari, Ricardo Ribeiro Nunes, Mirella Kielek Galvan Andrade, Francielle Fernandes Spies, Maikel Rosa de Oliveira, Luz Elena Durán-Carabali, Paula Rigon, Carlos Alexandre Netto, Ana Helena Paz, Luciano Stürmer de Frag. Short-Term Effects of Therapeutic Hypothermia Following Hypoxia-Ischemia in Neonatal Male and Female Rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-12-01. PMID:36453268. |
the animals of the hi group showed a reduction in the number of neurons in the ca1 and dentate gyrus (dg) regions of the hippocampus and th partially prevented neuronal death. |
2022-12-01 |
2023-08-14 |
human |
| Muhammad Zahid Khan, Yong-Bo Zheng, Kai Yuan, Ying Han, Lin L. Extracellular zinc regulates contextual fear memory formation in male rats through MMP-BDNF-TrkB pathway in dorsal hippocampus and basolateral amygdala. Behavioural brain research. 2022-11-28. PMID:36442645. |
male sprague dawley rats were trained for fear conditioning followed by in vivo microdialysis for collection of microdialysate samples from ca1 and ca3 regions of hippocampus and basolateral amygdala (bla). |
2022-11-28 |
2023-08-14 |
rat |
| Muhammad Zahid Khan, Yong-Bo Zheng, Kai Yuan, Ying Han, Lin L. Extracellular zinc regulates contextual fear memory formation in male rats through MMP-BDNF-TrkB pathway in dorsal hippocampus and basolateral amygdala. Behavioural brain research. 2022-11-28. PMID:36442645. |
extracellular zinc chelator caedta, bdnf scavenger trkb-fc, exogenous 7,8-dhf and matrix metalloproteinases (mmp) inhibitor were infused into the ca1 and ca3 regions of hippocampus and bla after cfc. |
2022-11-28 |
2023-08-14 |
rat |
| Muhammad Zahid Khan, Yong-Bo Zheng, Kai Yuan, Ying Han, Lin L. Extracellular zinc regulates contextual fear memory formation in male rats through MMP-BDNF-TrkB pathway in dorsal hippocampus and basolateral amygdala. Behavioural brain research. 2022-11-28. PMID:36442645. |
infusing the caedta, trkb-fc and mmp inhibitor into the ca1 and ca3 regions of hippocampus and bla disrupted the fear memory formation. |
2022-11-28 |
2023-08-14 |
rat |
| Farheen Farzana, Malcolm McConville, Thibault Renoir, Shanshan Li, Shuai Nie, Harvey Tran, Anthony J Hannan, Danny M Hatters, Berin A Boughto. Longitudinal spatial mapping of lipid metabolites reveals pre-symptomatic changes in the hippocampi of Huntington's disease transgenic mice. Neurobiology of disease. 2022-11-27. PMID:36436748. |
hippocampal subfields (ca1, ca3 and dg), which formed the highest density of inclusion formation in the mouse brain showed a reduction in the relative abundance of neuron-enriched lipids that have roles in neurotransmission, synaptic plasticity, neurogenesis, and er-stress protection. |
2022-11-27 |
2023-08-14 |
mouse |
| Yayan Luo, Yang Yu, Minling Zhang, Ni Fa. GluN1 antibody causes behavioral deficits in prepulse inhibition and memory through CaMKIIβ signaling. Journal of neuroimmunology. vol 373. 2022-11-23. PMID:36417808. |
in the present study, we found that passive infusion of glun1 antibody into the hippocampus of mice for 7 days led to decreased expression of glun1, phosphor-ser897-glun1, and ephrinb2 receptor (ephb2r); deficits in long-term potentiation (ltp) and synaptic transmission in the hippocampal ca1 area; impairment in prepulse inhibition (ppi); and deterioration of recognition memory in novel object recognition test. |
2022-11-23 |
2023-08-14 |
mouse |
| Samuel Treviño, Alfonso Díaz, Getsemaní González-López, Jorge Guevar. Differential biochemical-inflammatory patterns in the astrocyte-neuron axis of the hippocampus and frontal cortex in Wistar rats with metabolic syndrome induced by high fat or carbohydrate diets. Journal of chemical neuroanatomy. vol 126. 2022-11-14. PMID:36374648. |
at the brain level, it is noteworthy that the hcd group had an increase in lactate and glutamate concentration, reactive astrogliosis, immunoreactive cox2 neurons in the ca1 subfield hippocampus and frontal cortex, and high levels of pge2, tnf-α, il-1β, and il-6, and low bdnf immunoreactivity. |
2022-11-14 |
2023-08-14 |
rat |
| Yingjuan Xu, Jiling Zhang, Zeman Fang, Handi Zhan. The effects of social defeat stress on hippocampal glial cells and interleukin-6 in adolescence and adulthood. Neuroreport. vol 33. issue 18. 2022-11-11. PMID:36367792. |
microglia activation characterized by increased ionized calcium-binding adapter molecule 1 positive cell numbers or staining area in the ca1 and ca3 regions of the hippocampus were observed 24 h after the end of stress, which did not last into the adulthood. |
2022-11-11 |
2023-08-14 |
mouse |
| Kengo Suzuki, Yoshiaki Ohi, Toyohiro Sato, Yo Tsuda, Yuta Madokoro, Masayuki Mizuno, Kenichi Adachi, Yuto Uchida, Akira Haji, Kosei Ojika, Noriyuki Matsukaw. Reduction of glutamatergic activity through cholinergic dysfunction in the hippocampus of hippocampal cholinergic neurostimulating peptide precursor protein knockout mice. Scientific reports. vol 12. issue 1. 2022-11-10. PMID:36357544. |
the results, in combination with our previous reports that show the reduction of hippocampal theta power through a decrease of a region-specific choline acetyltransferase in the stratum oriens of ca1 and the decrease of acetylcholine concentration in the hippocampus, may indicate the defined cholinergic dysfunction in hcnp-pp ko mice. |
2022-11-10 |
2023-08-14 |
mouse |
| Tiantian Qiu, Qingze Zeng, Yusong Zhang, Xiao Luo, Xiaopei Xu, Xiaodong Li, Zhujing Shen, Kaicheng Li, Chao Wang, Peiyu Huang, Minming Zhang, Shouping Dai, Fei Xi. Altered Functional Connectivity Pattern of Hippocampal Subfields in Individuals with Objectively-defined Subtle Cognitive Decline and its Association with Cognition and Cerebrospinal Fluid Biomarkers. The European journal of neuroscience. 2022-11-07. PMID:36342704. |
we calculated the seed-based functional connectivity (fc) of hippocampal subfields (cornu ammonis1 [ca1], ca2/3/dentate gyrus [dg], and subiculum) with whole-brain voxels. |
2022-11-07 |
2023-08-14 |
human |
| Kumari Vandana Singh, Chandra Prakash, Jay Prakash Nirala, Ranjan Kumar Nanda, Paulraj Rajaman. Acute radiofrequency electromagnetic radiation exposure impairs neurogenesis and causes neuronal DNA damage in the young rat brain. Neurotoxicology. 2022-11-06. PMID:36336097. |
rf-emr exposure also induced degenerative changes and neuronal loss in dg neurons but had no effect on the ca3 and ca1 neurons of the hippocampus and cerebral cortex. |
2022-11-06 |
2023-08-14 |
rat |
| Han-Sol Lee, Jin-Hee Ha. Activity patterns of individual neurons and ensembles correlated with retrieval of a contextual memory in the dorsal CA1 of mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-11-04. PMID:36332977. |
activity patterns of individual neurons and ensembles correlated with retrieval of a contextual memory in the dorsal ca1 of mouse hippocampus. |
2022-11-04 |
2023-08-14 |
mouse |
| Han-Sol Lee, Jin-Hee Ha. Activity patterns of individual neurons and ensembles correlated with retrieval of a contextual memory in the dorsal CA1 of mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-11-04. PMID:36332977. |
the activation of a subpopulation of neurons in the dorsal ca1 (dca1) of the hippocampus is required for memory retrieval. |
2022-11-04 |
2023-08-14 |
mouse |