| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexander C Whitebirch, John J LaFrancois, Swati Jain, Paige Leary, Bina Santoro, Steven A Siegelbaum, Helen E Scharfma. Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy. Neuron. 2022-08-20. PMID:35987207. |
ex vivo electrophysiological recordings from acute hippocampal slices revealed a set of coordinated changes that enhance ca2 pc intrinsic excitability, reduce ca2 inhibitory input, and increase ca2 excitatory output to its major ca1 synaptic target. |
2022-08-20 |
2023-08-14 |
mouse |
| Derya Kaya, Serap Cilaker Micili, Ceren Kizmazoglu, Ali Osman Mucuoglu, Sibel Buyukcoban, Nevin Ersoy, Osman Yilmaz, Ahmet Turan Isi. Allopurinol attenuates repeated traumatic brain injury in old rats: A preliminary report. Experimental neurology. 2022-08-05. PMID:35931122. |
brain sections were processed for neuronal cell count in the hippocampus (ca1), dentate gyrus (dg), and prefrontal cortex (pc). |
2022-08-05 |
2023-08-14 |
rat |
| Cheng Ju, Yue Wang, Caixia Zang, Hui Liu, Fangyu Yuan, Jingwen Ning, Meiyu Shang, Jingwei Ma, Gen Li, Yang Yang, Xiuqi Bao, Dan Zhan. Inhibition of Dyrk1A Attenuates LPS-Induced Neuroinflammation via the TLR4/NF-κB P65 Signaling Pathway. Inflammation. 2022-08-02. PMID:35917097. |
in addition, immunohistochemical detection of ionized calcium-binding adapter molecule 1 (iba1) and nissl staining showed that harmine significantly attenuated microglia activation and neuronal damage in the ca1 region of hippocampus. |
2022-08-02 |
2023-08-14 |
mouse |
| Ana Lopes-Rocha, Thiago Ohno Bezerra, Roberta Zanotto, Inda Lages Nascimento, Angela Rodrigues, Cristiane Salu. The Antioxidant N-Acetyl-L-Cysteine Restores the Behavioral Deficits in a Neurodevelopmental Model of Schizophrenia Through a Mechanism That Involves Nitric Oxide. Frontiers in pharmacology. vol 13. 2022-07-29. PMID:35903343. |
analyses of markers involved in the inflammatory response, such as astrocytes (glial fibrillary acid protein, gfap) and microglia (binding adapter molecule 1, iba1), and parvalbumin (pv) positive gabaergic, were conducted in the prefrontal cortex [pfc, medial orbital cortex (mo) and prelimbic cortex (prl)] and dorsal and ventral hippocampus [ca1, ca2, ca3, and dentate gyrus (dg)] in rats under chronic treatment with nac. |
2022-07-29 |
2023-08-14 |
rat |
| Ana Lopes-Rocha, Thiago Ohno Bezerra, Roberta Zanotto, Inda Lages Nascimento, Angela Rodrigues, Cristiane Salu. The Antioxidant N-Acetyl-L-Cysteine Restores the Behavioral Deficits in a Neurodevelopmental Model of Schizophrenia Through a Mechanism That Involves Nitric Oxide. Frontiers in pharmacology. vol 13. 2022-07-29. PMID:35903343. |
nac increased the density of iba1 cells at pfc and of pv cells at mo and ca1 of the ventral hippocampus. |
2022-07-29 |
2023-08-14 |
rat |
| b' Ena \\xc5\\xa0pani\\xc4\\x87, Lea Langer Horvat, Katarina Ili\\xc4\\x87, Patrick R Hof, Goran \\xc5\\xa0imi\\xc4\\x8. NLRP1 Inflammasome Activation in the Hippocampal Formation in Alzheimer\'s Disease: Correlation with Neuropathological Changes and Unbiasedly Estimated Neuronal Loss. Cells. vol 11. issue 14. 2022-07-27. PMID:35883667.' |
to investigate the nlrp1 inflammasome activation in ad, we analyzed the expression of nlrp1, asc, cleaved gasdermin (cgsdmd), and active caspase-6 (casp-6) proteins in each hippocampal subdivision (hilar part of ca3, ca2/3, ca1, subiculum) of postmortem tissue of 9 cognitively healthy controls (hc) and 11 ad patients whose disease duration varied from 3 to 7 years after the clinical diagnosis. |
2022-07-27 |
2023-08-14 |
human |
| Joonyoung Kang, Wonjun Kang, Sue-Hyun Le. Stronger Memory Representation after Memory Reinstatement during Retrieval in the Human Hippocampus. NeuroImage. 2022-07-22. PMID:35868616. |
by tracking changes in the response patterns in the selected hippocampal and cortical regions over time during retrieval based on functional mri, we found that the representation of associative memory in ca3/dg became stronger even after cortical memory reinstatement, while ca1 showed significant memory representation at retrieval onset with the cortical reinstatement, but not afterwards. |
2022-07-22 |
2023-08-14 |
human |
| S Mokarrami, M Jahanshahi, L Elyasi, H Badelisarkala, M Khalil. Naringin prevents the reduction of the number of neurons and the volume of CA1 in a Scopolamine-Induced animal model of Alzheimer's disease (AD): A stereological study. The International journal of neuroscience. 2022-07-21. PMID:35861379. |
naringin administration at doses of 50, 100, and 200 mg/kg for 14 consecutive days, increased neuron density and the total number of neurons in the hippocampal ca1 area.we concluded that naringin could be effective in improving scopolamine-induced inhibitory passive avoidance memory deficits and that it appeared to increase the volume and density as well as the total number of neurons in the ca1 area of the alzheimer's rat hippocampus. |
2022-07-21 |
2023-08-14 |
rat |
| Guohua Wang, Limei Chen, He Chen, Yitong Li, Yuesi Xu, Yanli Xing, Lu Zhang, Juan L. Glutamate receptor interacting protein 1 in the dorsal CA1 drives AMPA receptor endocytosis and exocytosis bidirectionally and mediates forgetting, exploratory, and anxiety-like behavior. Neuroscience. 2022-07-21. PMID:35863680. |
endocytosis of glua2-containing alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (ampars) in ca1 of the hippocampus regulates forgetting; deficits in forgetting nociceptive memory can induce serious stress disorders. |
2022-07-21 |
2023-08-14 |
Not clear |
| Guohua Wang, Limei Chen, He Chen, Yitong Li, Yuesi Xu, Yanli Xing, Lu Zhang, Juan L. Glutamate receptor interacting protein 1 in the dorsal CA1 drives AMPA receptor endocytosis and exocytosis bidirectionally and mediates forgetting, exploratory, and anxiety-like behavior. Neuroscience. 2022-07-21. PMID:35863680. |
lentivirus-mediated interference of grip1 expression or function in the dorsal ca1 of the hippocampus indicated that grip1 overexpression enhanced spatial memory, impaired forgetting in a barnes maze, and induced anxiety-like behavior in the open field and elevated plus-maze test. |
2022-07-21 |
2023-08-14 |
Not clear |
| Behzad Garmabi, Reza Mohaddes, Fatemeh Rezvani, Fahimeh Mohseni, Hossein Khastar, Mehdi Khaksar. Erythropoietin improve spatial memory impairment following methamphetamine neurotoxicity by inhibition of apoptosis, oxidative stress and neuroinflammation in CA1 area of hippocampus. Journal of chemical neuroanatomy. 2022-07-16. PMID:35842017. |
erythropoietin improve spatial memory impairment following methamphetamine neurotoxicity by inhibition of apoptosis, oxidative stress and neuroinflammation in ca1 area of hippocampus. |
2022-07-16 |
2023-08-14 |
Not clear |
| Evgeniya V Markova, Maria A Knyazheva, Maria A Tikhonova, Tamara G Amstislavskay. Structural and functional characteristics of the hippocampus in depressive-like recipients after transplantation of in vitro caffeine-modulated immune cells. Neuroscience letters. 2022-07-15. PMID:35839995. |
in depressive-like recipients, an increase in the density of pyramidal neurons in ca1 and ca3 hippocampal regions, accompanied with augmented level of bdnf, decreased levels of pro-inflammatory (il-1β, il-6, inf-γ, and tnf-α) and increased levels of anti-inflammatory (il-10 and il-4) cytokines was found. |
2022-07-15 |
2023-08-14 |
mouse |
| Nazanin Mozafari, Jalal Hassanshahi, Hamid Ostadebrahimi, Ali Shamsizadeh, Fatemeh Ayoobi, Elham Hakimizadeh, Mohammad Pak-Hashemi, Ayat Kaeid. Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons. Acta neurobiologiae experimentalis. vol 82. issue 2. 2022-07-14. PMID:35833817. |
this study evaluates the neuroprotective effect of achillea millefolium (ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the ca1 region of the rat hippocampus. |
2022-07-14 |
2023-08-14 |
human |
| Nazanin Mozafari, Jalal Hassanshahi, Hamid Ostadebrahimi, Ali Shamsizadeh, Fatemeh Ayoobi, Elham Hakimizadeh, Mohammad Pak-Hashemi, Ayat Kaeid. Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons. Acta neurobiologiae experimentalis. vol 82. issue 2. 2022-07-14. PMID:35833817. |
caspase‑3, bax, and bcl‑2 proteins expression in the ca1 region of hippocampal tissue was analyzed using the western blot method. |
2022-07-14 |
2023-08-14 |
human |
| Nuri Jeong, Annabelle C Singe. Learning from inhibition: Functional roles of hippocampal CA1 inhibition in spatial learning and memory. Current opinion in neurobiology. vol 76. 2022-07-10. PMID:35810533. |
here, we review emerging evidence of ca1 hippocampal interneurons' role in local circuit computations that support spatial learning and memory and discuss open questions about ca1 interneurons in spatial learning. |
2022-07-10 |
2023-08-14 |
Not clear |
| Ying Wei, Li Xiao, Weihao Fan, Jing Zou, Hong Yang, Bo Liu, Yi Ye, Di Wen, Linchuan Lia. Astrocyte Activation, but not Microglia, Is Associated with the Experimental Mouse Model of Schizophrenia Induced by Chronic Ketamine. Journal of molecular neuroscience : MN. 2022-07-08. PMID:35802289. |
moreover, chronic ketamine treatment enhanced gfap expression in ca1 and dg regions of the hippocampus but did not influence the expression of iba-1. |
2022-07-08 |
2023-08-14 |
mouse |
| Daeho Ryu, Youjin Lee, Yongseung Lee, Yena Lee, Seoyoung Hwang, Yong-Kweon Kim, Sang Beom Jun, Hyang Woon Lee, Chang-Hyeon J. Silicon optrode array with monolithically integrated SU-8 waveguide and single LED light source. Journal of neural engineering. 2022-07-07. PMID:35797969. |
in-vivo experiment at the hippocampus region ca1 and ca2 demonstrated the capability of optical stimulation and neural signal recording through the led and su-8 waveguide coupled silicon optrode array. |
2022-07-07 |
2023-08-14 |
Not clear |
| Michaela Shishmanova-Doseva, Dimitrinka Atanasova, Lyubka Ioanidu, Yordanka Uzunova, Milena Atanasova, Lyudmil Peychev, Jana Tchekalarov. The anticonvulsant effect of chronic treatment with topiramate after pilocarpine-induced status epilepticus is accompanied by a suppression of comorbid behavioral impairments and robust neuroprotection in limbic regions in rats. Epilepsy & behavior : E&B. vol 134. 2022-07-06. PMID:35792414. |
the drug treatment suppressed the se-induced neuronal damage in limbic structures, including the dorsal (ca1 and ca2 subfield), the ventral (ca1, ca2 and ca3) hippocampus, the basolateral amygdala, and the piriform cortex, while was ineffective against the surge in the oxidative stress and inflammation. |
2022-07-06 |
2023-08-14 |
rat |
| Wei Zhu, Fengming Wu, Jiong Li, Lianghui Meng, Wenjun Zhang, Huijie Zhang, Shuhan Cha, Jifeng Zhang, Guoqing Gu. Impaired learning and memory generated by hyperthyroidism is rescued by restoration of AMPA and NMDA receptors function. Neurobiology of disease. 2022-07-01. PMID:35777536. |
mature dendritic spines in the hippocampal ca1 region of hyperthyroid mice were significantly decreased, accompanied by decreased level of ampa- and nmda-type glutamate receptors in the hippocampus. |
2022-07-01 |
2023-08-14 |
mouse |
| Raghava Jagadeesh Salaka, Kala P Nair, Reddy Bedadala Sasibhushana, Deepashree Udayakumar, Bindu M Kutty, Bettadapura N Srikumar, Byrathnahalli S Shankaranarayana Ra. Differential effects of levetiracetam on hippocampal CA1 synaptic plasticity and molecular changes in the dentate gyrus in epileptic rats. Neurochemistry international. 2022-06-26. PMID:35753511. |
following lev treatment, schaffer collateral - ca1 (ca3-ca1) synaptic plasticity and structural changes in hippocampal subregions ca3 and ca1 were evaluated. |
2022-06-26 |
2023-08-14 |
rat |