| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ryszard Plut. Alzheimer's Disease Connected Genes in the Post-Ischemic Hippocampus and Temporal Cortex. Genes. vol 13. issue 6. 2022-06-24. PMID:35741821. |
in the ca1 and ca3 regions of the hippocampus and temporal cortex, genes related to alzheimer's disease, such as the |
2022-06-24 |
2023-08-14 |
Not clear |
| Ryszard Pluta, Sławomir Januszewski, Stanisław J Czuczwa. Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer's Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation-Fantasy or Reality? International journal of molecular sciences. vol 23. issue 12. 2022-06-24. PMID:35743035. |
the death of pyramidal neurons in especially the ca1 area of the hippocampus, increased permeability of the blood-brain barrier, neuroinflammation, amyloid accumulation, tau protein dysfunction, brain atrophy, cognitive deficits and dementia are considered an integral part of the phenomena occurring during brain neurodegeneration after ischemia. |
2022-06-24 |
2023-08-14 |
Not clear |
| Peter J Schuette, Juliane M Ikebara, Sandra Maesta-Pereira, Anita Torossian, Ekayana Sethi, Alexandre H Kihara, Jonathan C Kao, Fernando M C V Reis, Avishek Adhikar. GABAergic CA1 neurons are more stable following context changes than glutamatergic cells. Scientific reports. vol 12. issue 1. 2022-06-20. PMID:35725588. |
the ca1 region of the hippocampus contains both glutamatergic pyramidal cells and gabaergic interneurons. |
2022-06-20 |
2023-08-14 |
mouse |
| Peter J Schuette, Juliane M Ikebara, Sandra Maesta-Pereira, Anita Torossian, Ekayana Sethi, Alexandre H Kihara, Jonathan C Kao, Fernando M C V Reis, Avishek Adhikar. GABAergic CA1 neurons are more stable following context changes than glutamatergic cells. Scientific reports. vol 12. issue 1. 2022-06-20. PMID:35725588. |
in contrast, these classic hippocampal experiments have never been conducted with ca1 gabaergic cells. |
2022-06-20 |
2023-08-14 |
mouse |
| Scheila Daiane Schmidt, Carolina Garrido Zinn, Lorena Evelyn Cavalcante, Flávia Fagundes Ferreira, Cristiane Regina Guerino Furini, Ivan Izquierdo, Jociane de Carvalho Myski. Participation of hippocampal 5-HT Neuroscience. 2022-06-19. PMID:35718219. |
focusing on the more recently described 5-ht receptors, we investigated in the ca1 region of the dorsal hippocampus the participation of 5-ht |
2022-06-19 |
2023-08-14 |
Not clear |
| Cai-N Cheng, Shaw-Jye Wu, Andrew Chih Wei Huan. Environmental Enrichment Components Required to Reduce Methamphetamine-Induced Behavioral Sensitization in Mice: Examination of Behaviors and Neural Substrates. Journal of clinical medicine. vol 11. issue 11. 2022-06-10. PMID:35683439. |
the c-fos expression analysis showed that the medial prefrontal cortex (i.e., cingulate cortex 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), nucleus accumbens (nac), basolateral amygdala (bla), ventral tegmental area (vta), caudate-putamen (cpu), and hippocampus (i.e., ca1, ca3, and dentate gyrus (dg)) contributed to mamph-induced behavioral sensitization. |
2022-06-10 |
2023-08-14 |
mouse |
| Dylan C M Yeates, Dallas Leavitt, Sajeevan Sujanthan, Nisma Khan, Denada Alushaj, Andy C H Lee, Rutsuko It. Parallel ventral hippocampus-lateral septum pathways differentially regulate approach-avoidance conflict. Nature communications. vol 13. issue 1. 2022-06-10. PMID:35688838. |
the ventral ca3 (vca3) and ca1 (vca1) subfields of the ventral hippocampus (vhpc) have been shown to facilitate avoidance and approach behavior, respectively, in the face of motivational conflict, but the neural circuits by which this subfield-specific regulation is implemented is unknown. |
2022-06-10 |
2023-08-14 |
rat |
| Nicholas M DiCola, Alexa L Lacy, Omar J Bishr, Kathryn M Kimsey, Jenna L Whitney, Sarah D Lovett, Sara N Burke, Andrew P Maure. Advanced age has dissociable effects on hippocampal CA1 ripples and CA3 high frequency events in male rats. Neurobiology of aging. vol 117. 2022-06-07. PMID:35665647. |
sharp wave/ripples/high frequency events (hfes) are transient bursts of depolarization in hippocampal subregions ca3 and ca1 that occur during rest and pauses in behavior. |
2022-06-07 |
2023-08-14 |
rat |
| Ryuki Tsuchida, Taisei Yamaguchi, Daisuke Funabashi, Yusuke Koumi, Ichiro Kita, Takeshi Nishijim. Exercise type influences the effect of an acute bout of exercise on hippocampal neuronal activation in mice. Neuroscience letters. 2022-06-06. PMID:35660647. |
immunohistochemical examination of c-fos, a marker of neuronal activation, revealed that treadmill exercise at 15 m/min (t15) significantly increased c-fos expression in all subfields of the hippocampus (dentate gyrus dg, ca1, ca3), but rotarod exercise at 30 rpm (r30) did not, as compared with the respective control groups. |
2022-06-06 |
2023-08-14 |
mouse |
| Yukie Yamahashi, You-Hsin Lin, Akihiro Mouri, Sho Iwanaga, Kazuhiro Kawashima, Yuya Tokumoto, Yo Watanabe, Md Omar Faruk, Xinjian Zhang, Daisuke Tsuboi, Takashi Nakano, Naoaki Saito, Taku Nagai, Kiyofumi Yamada, Kozo Kaibuch. Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning. Molecular psychiatry. 2022-06-06. PMID:35665767. |
donepezil induced pak activation in both accumbal d2r-msns and in the ca1 region of the hippocampus and enhanced d2r-msn-mediated aversive learning. |
2022-06-06 |
2023-08-14 |
mouse |
| Ji-Eun Kim, Duk-Shin Lee, Tae-Hyun Kim, Tae-Cheon Kan. CDDO-Me Attenuates CA1 Neuronal Death by Facilitating RalBP1-Mediated Mitochondrial Fission and 4-HNE Efflux in the Rat Hippocampus Following Status Epilepticus. Antioxidants (Basel, Switzerland). vol 11. issue 5. 2022-05-28. PMID:35624848. |
cddo-me attenuates ca1 neuronal death by facilitating ralbp1-mediated mitochondrial fission and 4-hne efflux in the rat hippocampus following status epilepticus. |
2022-05-28 |
2023-08-13 |
rat |
| Barbara Puhahn-Schmeiser, Tobias Kleemann, Ramazan Jabbarli, Hans H Bock, Jürgen Beck, Thomas M Freima. Granule cell dispersion in two mouse models of temporal lobe epilepsy and reeler mice is associated with changes in dendritic orientation and spine distribution. Hippocampus. 2022-05-27. PMID:35621370. |
temporal lobe epilepsy is characterized by hippocampal neuronal death in ca1 and hilus. |
2022-05-27 |
2023-08-13 |
mouse |
| Thomas M Sanderson, Liam T Ralph, Mascia Amici, Ai Na Ng, Bong-Kiun Kaang, Min Zhuo, Sang Jeong Kim, John Georgiou, Graham L Collingridg. Selective Recruitment of Presynaptic and Postsynaptic Forms of mGluR-LTD. Frontiers in synaptic neuroscience. vol 14. 2022-05-26. PMID:35615440. |
in area ca1 of the hippocampus, long-term depression (ltd) can be induced by activating group i metabotropic glutamate receptors (mglurs), with the selective agonist dhpg. |
2022-05-26 |
2023-08-13 |
Not clear |
| Zhiquan Zhang, Qing Ma, Ravikanth Velagapudi, William E Barclay, Ramona M Rodriguiz, William C Wetsel, Ting Yang, Mari L Shinohara, Niccolò Terrand. Annexin-A1 Tripeptide Attenuates Surgery-Induced Neuroinflammation and Memory Deficits Through Regulation the NLRP3 Inflammasome. Frontiers in immunology. vol 13. 2022-05-23. PMID:35603196. |
surgery triggered asc specks formation in ca1 hippocampal microglia, but without inducing significant morphological changes in nlrp3 and asc knockout mice. |
2022-05-23 |
2023-08-13 |
mouse |
| Ana Paula Rodrigues Martini, Eduarda Hoeper, Thales Avila Pedroso, Andrey Vinicios Soares Carvalho, Felipe Kawa Odorcyk, Rafael Bandeira Fabres, Natividade de Sá Couto Pereira, Carlos Alexandre Nett. Effects of Acrobatic Training on Spatial Memory and Astrocytic Scar in CA1 subfield of Hippocampus after Chronic Cerebral Hypoperfusion in Male and Female Rats. Behavioural brain research. 2022-05-23. PMID:35605797. |
effects of acrobatic training on spatial memory and astrocytic scar in ca1 subfield of hippocampus after chronic cerebral hypoperfusion in male and female rats. |
2022-05-23 |
2023-08-13 |
rat |
| Mansour Sayyah, Mehdi Seydyousefi, Abdorreza Eghbal Moghanlou, Gerlinde A S Metz, Nabi Shamsaei, Mohammad Hasan Faghfoori, Zeinab Faghfoor. Activation of BDNF- and VEGF-mediated Neuroprotection by Treadmill Exercise Training in Experimental Stroke. Metabolic brain disease. 2022-05-21. PMID:35596908. |
this study was designed to examine the effect of aerobic exercise on post ischemia/reperfusion injury on concentration and expression of brain-derived neurotrophic factor (bdnf) and vascular endothelial growth factor (vegf) after inducing a neuronal loss in ca1 region of hippocampus in male wistar rats. |
2022-05-21 |
2023-08-13 |
rat |
| Ashif Iqubal, Mohammad Kashif Iqubal, Sumit Sharma, Mohd Wasim, Mohamed A Alfaleh, Shadab Md, Sanjula Baboota, Javed Ali, Syed Ehtaishamul Haqu. Pathogenic mechanisms and therapeutic promise of phytochemicals and nanocarriers based drug delivery against radiotherapy-induced neurotoxic manifestations. Drug delivery. vol 29. issue 1. 2022-05-11. PMID:35543534. |
based on the preclinical and clinical investigations, the profound role of increased oxidative stress, nuclear translocation of nf-kb, production of proinflammatory cytokines such as tnf-α, il-6, il-β, increased level of mmps, increased apoptosis, reduced angiogenesis, neurogenesis, and histological aberrations in ca1, ca2, ca3 and dg region of the hippocampus have been reported. |
2022-05-11 |
2023-08-13 |
Not clear |
| Qian Chen, Yichen Cai, Xiaoyu Zhu, Jing Wang, Feng Gao, Mingfeng Yang, Leilei Mao, Zongyong Zhang, Baoliang Su. Edaravone Dexborneol Treatment Attenuates Neuronal Apoptosis and Improves Neurological Function by Suppressing 4-HNE-Associated Oxidative Stress After Subarachnoid Hemorrhage. Frontiers in pharmacology. vol 13. 2022-05-09. PMID:35529450. |
our results showed that a post-sah therapeutic regimen with edaravone dexborneol helped improve neurological function up to 21 days after sah surgery and demonstrated a greater beneficial effect than edaravone alone, accompanied by an obvious inhibition of neuronal apoptosis in the ca1 hippocampus and basal cortex regions. |
2022-05-09 |
2023-08-13 |
human |
| Qian Chen, Yichen Cai, Xiaoyu Zhu, Jing Wang, Feng Gao, Mingfeng Yang, Leilei Mao, Zongyong Zhang, Baoliang Su. Edaravone Dexborneol Treatment Attenuates Neuronal Apoptosis and Improves Neurological Function by Suppressing 4-HNE-Associated Oxidative Stress After Subarachnoid Hemorrhage. Frontiers in pharmacology. vol 13. 2022-05-09. PMID:35529450. |
notably, edaravone dexborneol treatment significantly inhibited the expression of another lipid peroxidation product, 4-hydroxynonenal (4-hne), in the ca1 hippocampus and basal cortex, which are vital participants in the process of neuronal oxidative damage and death after sah because of their acute cytotoxicity. |
2022-05-09 |
2023-08-13 |
human |
| Lennart Seizer, Sadegh Rahimi, Sandra Santos-Sierra, Meinrad Drexe. Expression of toll like receptor 8 (TLR8) in specific groups of mouse hippocampal interneurons. PloS one. vol 17. issue 5. 2022-05-04. PMID:35507634. |
somatostatin-positive interneurons co-expressing tlr8 were mainly present in hippocampal sector ca3 but rare in the dentate gyrus and ca1. |
2022-05-04 |
2023-08-13 |
mouse |