| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sonja Fixemer, Corrado Ameli, Gaël Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Jean-Jacques Gérardy, Naguib Mechawar, Alexander Skupin, Michel Mittelbronn, David S Bouvie. Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies. Acta neuropathologica communications. vol 10. issue 1. 2022-03-17. PMID:35296366. |
however, the subregional deterioration pattern of the hippocampus differs between ad and dlb with the ca1 subfield being more severely affected in ad. |
2022-03-17 |
2023-08-13 |
Not clear |
| Sonja Fixemer, Corrado Ameli, Gaël Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Jean-Jacques Gérardy, Naguib Mechawar, Alexander Skupin, Michel Mittelbronn, David S Bouvie. Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies. Acta neuropathologica communications. vol 10. issue 1. 2022-03-17. PMID:35296366. |
to this purpose, we employed an automated pipeline for analysis of 3d confocal microscopy images to assess ca1, ca3 and dg/ca4 subfields microglia responses in post-mortem hippocampal samples from late-onset ad (n = 10), dlb (n = 8) and age-matched control (ctl) (n = 11) individuals. |
2022-03-17 |
2023-08-13 |
Not clear |
| Hang Xing, Xiong Han, Sihan Xu, Zhongyu Sun, Shijun Yan. Brivaracetam Modulates Short-Term Synaptic Activity and Low-Frequency Spontaneous Brain Activity by Delaying Synaptic Vesicle Recycling in Two Distinct Rodent Models of Epileptic Seizures. Journal of molecular neuroscience : MN. 2022-03-12. PMID:35278193. |
in our study, the electrophysiological field excitatory post-synaptic potential (fepsp) recordings were performed in rat hippocampal brain slices from the ca1 region by stimulation of the schaffer collateral/commissural pathway with or without brv (30 μm for 3 h) in control or epileptic seizure (induced by pilocarpine (pilo) or high potassium (h-k |
2022-03-12 |
2023-08-13 |
rat |
| Hongxuan Kuang, Wenji Zhou, Yingwei Zeng, Da Xu, Wanqi Zhu, Shengjie Lin, Ruifang Fa. Dose makes poison: Insights into the neurotoxicity of perinatal and juvenile exposure to environmental doses of 16 priority-controlled PAHs. Chemosphere. 2022-03-08. PMID:35257710. |
compared with the control mice, only those exposed to 50 μg/kg/day pahs had significantly lower ltp in hippocampal ca1 region and dendritic spine density in hippocampal dg region (p < 0.05). |
2022-03-08 |
2023-08-13 |
mouse |
| Zhu-Qing He, Peng-Fei Huan, Li Wang, Jian-Cheng H. Paeoniflorin ameliorates cognitive impairment in Parkinson's disease via JNK/p53 signaling. Metabolic brain disease. 2022-03-01. PMID:35230626. |
additionally, pf improved 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced neuronal injury by inhibiting apoptosis in hippocampal neurons of the ca1 and ca3, and upregulating psd-95 as well as syn protein levels. |
2022-03-01 |
2023-08-13 |
mouse |
| Tatyana Strekalova, Dmitrii Pavlov, Alexander Trofimov, Daniel C Anthony, Andrei Svistunov, Andrey Proshin, Aleksei Umriukhin, Alexei Lyundup, Klaus-Peter Lesch, Raymond Cespugli. Hippocampal Over-Expression of Cyclooxygenase-2 (COX-2) Is Associated with Susceptibility to Stress-Induced Anhedonia in Mice. International journal of molecular sciences. vol 23. issue 4. 2022-02-26. PMID:35216176. |
anhedonic (susceptible) but not non-anhedonic (resilient) animals exhibited elevated cox-2 mrna levels, increased numbers of cox-2 and iba-1-positive cells in the dentate gyrus and the ca1 area, and decreased numbers of ki67-positive cells in the subgranular zone of the hippocampus. |
2022-02-26 |
2023-08-13 |
mouse |
| Hannah Twarkowksi, Victor Steininger, Min Jae Kim, Amar Saha. A dentate gyrus- CA3 inhibitory circuit promotes evolution of hippocampal-cortical ensembles during memory consolidation. eLife. vol 11. 2022-02-22. PMID:35191834. |
memories encoded in the dentate gyrus (dg) - ca3 circuit of the hippocampus are routed from ca1 to anterior cingulate cortex (acc) for consolidation. |
2022-02-22 |
2023-08-13 |
Not clear |
| Behzad Dehqanizadeh, Ziya Fallah Mohammadi, Abdol Hossein Taheri Kalani, Seyed Javad Mirghan. Effect of Early Exercise on Inflammatory Parameters and Apoptosis in CA1 Area of the Hippocampus Following Cerebral Ischemia-reperfusion in Rats. Brain research bulletin. 2022-02-21. PMID:35189318. |
effect of early exercise on inflammatory parameters and apoptosis in ca1 area of the hippocampus following cerebral ischemia-reperfusion in rats. |
2022-02-21 |
2023-08-13 |
rat |
| Behzad Dehqanizadeh, Ziya Fallah Mohammadi, Abdol Hossein Taheri Kalani, Seyed Javad Mirghan. Effect of Early Exercise on Inflammatory Parameters and Apoptosis in CA1 Area of the Hippocampus Following Cerebral Ischemia-reperfusion in Rats. Brain research bulletin. 2022-02-21. PMID:35189318. |
the purpose of this study was to evaluate the effect of early exercise on inflammatory parameters and apoptosis in the ca1 area of the hippocampus following cerebral i/r in adult male rats. |
2022-02-21 |
2023-08-13 |
rat |
| Yu Zhang, Qi Wu, Yu Ren, Ye Zhang, Linyin Fen. A53T α-synuclein induces neurogenesis impairment and cognitive dysfunction in line M83 transgenic mice and reduces the proliferation of embryonic neural stem cells. Brain research bulletin. 2022-02-19. PMID:35182691. |
golgi staining indicated that the apical neuronal dendritic spines of hippocampal ca1 neurons were significantly reduced in 6-month-old homozygotes and heterozygotes, although map2 protein expression revealed no significant difference in the hippocampus among wild-type mice, homozygotes and heterozygotes. |
2022-02-19 |
2023-08-13 |
mouse |
| Ying Hao Yu, Yeou San Lim, Chen Yin Ou, Kai Chieh Chang, Arthur C Tsai, Fang Chih Chang, Andrew Chih Wei Huan. The Medial Prefrontal Cortex, Nucleus Accumbens, Basolateral Amygdala, and Hippocampus Regulate the Amelioration of Environmental Enrichment and Cue in Fear Behavior in the Animal Model of PTSD. Behavioural neurology. vol 2022. 2022-02-18. PMID:35178125. |
the present study addressed this issue and examined whether the medial prefrontal cortex (mpfc, including the cingulate cortex 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), the nucleus accumbens (nac), the basolateral amygdala (bla), and the hippocampus (e.g., ca1, ca3, and dentate gyrus (dg)) regulated the amelioration of the ee, cue, or the combination of ee and cue. |
2022-02-18 |
2023-08-13 |
Not clear |
| Ying Hao Yu, Yeou San Lim, Chen Yin Ou, Kai Chieh Chang, Arthur C Tsai, Fang Chih Chang, Andrew Chih Wei Huan. The Medial Prefrontal Cortex, Nucleus Accumbens, Basolateral Amygdala, and Hippocampus Regulate the Amelioration of Environmental Enrichment and Cue in Fear Behavior in the Animal Model of PTSD. Behavioural neurology. vol 2022. 2022-02-18. PMID:35178125. |
the mpfc (i.e., the cg1, prl, and il) and the hippocampus (i.e., the ca1, ca3, and dg) downregulated the c-fos expression in the suppression of the cue in fear behavior. |
2022-02-18 |
2023-08-13 |
Not clear |
| Daniele Lana, Elisabetta Gerace, Giada Magni, Francesca Cialdai, Monica Monici, Guido Mannaioni, Maria Grazia Giovannin. Hypoxia/Ischemia-Induced Rod Microglia Phenotype in CA1 Hippocampal Slices. International journal of molecular sciences. vol 23. issue 3. 2022-02-15. PMID:35163344. |
hypoxia/ischemia-induced rod microglia phenotype in ca1 hippocampal slices. |
2022-02-15 |
2023-08-13 |
rat |
| Ya-Fei Zhao, Wen-Jing Ren, Ying Zhang, Jin-Rong He, Hai-Yan Yin, Yang Liao, Patrizia Rubini, Jan M Deussing, Alexei Verkhratsky, Zeng-Qiang Yuan, Peter Illes, Yong Tan. High, in Contrast to Low Levels of Acute Stress Induce Depressive-like Behavior by Involving Astrocytic, in Addition to Microglial P2X7 Receptors in the Rodent Hippocampus. International journal of molecular sciences. vol 23. issue 3. 2022-02-15. PMID:35163829. |
in hippocampal slices of mice and rats, only foot shock increased the current responses to locally applied dibenzoyl-atp (bz-atp) in ca1 astrocytes; in contrast, tst and restraint depressed these responses. |
2022-02-15 |
2023-08-13 |
mouse |
| Meinrad Drexel, Sadegh Rahimi, Günther Sper. Silencing of hippocampal somatostatin interneurons induces recurrent spontaneous limbic seizures in mice. Neuroscience. 2022-02-15. PMID:35167940. |
we now investigated whether impairing this type of feed-back inhibition by selectively inhibiting gaba release from sst expressing interneurons in hippocampal sector ca1 and subiculum may be sufficient to induce spontaneous recurrent seizures. |
2022-02-15 |
2023-08-13 |
mouse |
| Yeseul Lee, Zuner A Bortolotto, Clarrisa A Bradley, Thomas M Sanderson, Min Zhuo, Bong-Kiun Kaang, Graham L Collingridg. The GSK-3 Inhibitor CT99021 Enhances the Acquisition of Spatial Learning and the Accuracy of Spatial Memory. Frontiers in molecular neuroscience. vol 14. 2022-02-14. PMID:35153671. |
systemic administration of a highly selective gsk-3 inhibitor, ct99021, reversibly blocked nmdar-dependent ltd in the ca1 region of the hippocampus in anesthetized adult mice. |
2022-02-14 |
2023-08-13 |
mouse |
| Vahid Sheibani, Mohammad Amin Rajizadeh, Mohammad Abbas Bejeshk, Elham Haghparast, Masoumeh Nozari, Saeed Esmaeili-Mahani, Akram Nezhad. The effects of neurosteroid allopregnanolone on synaptic dysfunction in the hippocampus in experimental parkinsonism rats: An electrophysiological and molecular study. Neuropeptides. vol 92. 2022-02-14. PMID:35158223. |
these findings showed that partial dopamine depletion led to unusual synaptic plasticity in the ca1 as well as the decrease in synaptic proteins in the hippocampus. |
2022-02-14 |
2023-08-13 |
rat |
| Fatemeh Khani, Ali Pourmotabbed, Narges Hosseinmardi, Seyed Ershad Nedaei, Yaghoub Fathollahi, Hossein Aziz. Impairment of spatial memory and dorsal hippocampal synaptic plasticity in adulthood due to adolescent morphine exposure. Progress in neuro-psychopharmacology & biological psychiatry. 2022-02-12. PMID:35149126. |
this study investigated the effects of adolescent morphine exposure in spatial learning and memory and synaptic plasticity of the ca1 area of the dorsal hippocampus. |
2022-02-12 |
2023-08-13 |
rat |
| Marta Scarioni, Priya Gami-Patel, Carel F W Peeters, Florianne de Koning, Harro Seelaar, Merel O Mol, John C van Swieten, Annemieke J M Rozemuller, Jeroen J M Hoozemans, Yolande A L Pijnenburg, Anke A Dijkstr. Psychiatric symptoms of frontotemporal dementia and subcortical (co-)pathology burden: new insights. Brain : a journal of neurology. 2022-02-09. PMID:35136978. |
in subcortical regions, the presence of psychiatric symptoms showed positive correlations with increased hippocampal pathology burden: hallucinations with tdp-43 in the granular layer (r = 0.33), mania with tdp-43 in ca1 (r = 0.35), depression with tdp-43 in ca3 and with parahippocampal tau (r = 0.30 and r = 0.23), and delusions with ca3 tau (r = 0.26) and subicular amyloid-beta (r = 0.25). |
2022-02-09 |
2023-08-13 |
Not clear |
| Jonas-Frederic Sauer, Shani Folschweiller, Marlene Barto. Topographically organized representation of space and context in the medial prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 6. 2022-02-05. PMID:35121665. |
in particular, it has remained unclear how the topography of direct anatomical connections from hippocampus to neocortex affects spatial tuning depth, and whether the dynamics of spatial coding in the hippocampal output region ca1, such as remapping in novel environments, is transmitted to the neocortex. |
2022-02-05 |
2023-08-13 |
mouse |