| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ruike Wang, Zuntao Wu, Mengchen Liu, Yingying Wu, Qiong Li, Yue Ba, Huizhen Zhang, Xuemin Cheng, Guoyu Zhou, Hui Huan. Resveratrol reverses hippocampal synaptic markers injury and SIRT1 inhibition against developmental Pb exposure. Brain research. vol 1767. 2021-12-09. PMID:34175265. |
the dg, ca1 and ca3 regions of the hippocampus showed a considerable increase in the expression of pre- and postsynaptic proteins (p < 0.001 vs 0.2% pb group). |
2021-12-09 |
2023-08-13 |
rat |
| Jehoon Lee, Vishal Naik, Marcus Orzabal, Raine Lunde-Young, Jayanth Ramados. Morphological alteration in rat hippocampal neuronal dendrites following chronic binge prenatal alcohol exposure. Brain research. vol 1768. 2021-12-09. PMID:34297994. |
pae increased dendritic arborization and complexities of ca1, ca2/3, and dg neurons in the pnd 10 rat hippocampus. |
2021-12-09 |
2023-08-13 |
rat |
| Francesca Romana Rizzo, Livia Guadalupi, Krizia Sanna, Valentina Vanni, Diego Fresegna, Francesca De Vito, Alessandra Musella, Silvia Caioli, Sara Balletta, Silvia Bullitta, Antonio Bruno, Ettore Dolcetti, Mario Stampanoni Bassi, Fabio Buttari, Luana Gilio, Georgia Mandolesi, Diego Centonze, Antonietta Gentil. Exercise protects from hippocampal inflammation and neurodegeneration in experimental autoimmune encephalomyelitis. Brain, behavior, and immunity. vol 98. 2021-12-09. PMID:34391817. |
indeed, exercise significantly reduced microgliosis in the ca1 area, the expression of tumour necrosis factor (tnf) in microglia and, to a lesser extent, the hippocampal level of interleukin 1 beta (il-1β), previously shown to contribute to aberrant synaptic plasticity in the eae hippocampus. |
2021-12-09 |
2023-08-13 |
mouse |
| Robert Numa. The Prefrontal-Hippocampal Comparator: Volition and Episodic Memory. Perceptual and motor skills. vol 128. issue 6. 2021-12-09. PMID:34424092. |
the self-referential component of episodic memory in humans is mediated by the corollary discharge (the efference copy of the action plan developed by prefrontal cortex and transmitted to hippocampus where it is stored as a working memory; ca1 uses this efference copy to compare the expected consequences of action to the actual consequences of action). |
2021-12-09 |
2023-08-13 |
Not clear |
| Akila Pai, Lara V Marcuse, Judy Alper, Bradley N Delman, John W Rutland, Rebecca E Feldman, Patrick R Hof, Madeline Fields, James Young, Priti Balchandan. Detection of Hippocampal Subfield Asymmetry at 7T With Automated Segmentation in Epilepsy Patients With Normal Clinical Strength MRIs. Frontiers in neurology. vol 12. 2021-12-07. PMID:34867703. |
in this study, we present a novel application of the automated segmentation of hippocampal subfields (ashs) software to determine subfield volumes of the ca1, ca2/3, ca4/dg, and the subiculum using ultra high-field 7t mri scans, including t1-weighted mp2rage and t2-tse sequences, in 27 patients with either mesial temporal lobe epilepsy (mtle) or neocortical epilepsy (ne) compared to age and gender matched healthy controls. |
2021-12-07 |
2023-08-13 |
Not clear |
| Dongmeng Liu, Dahui Xue, Wencan Lu, Zhuochun Yang, Li Li, Beibei Xia, Jinhua Wei, Xianxiong Chen, Yi Yang, Xiaomei Wang, Guimiao Li. BDE-47 induced PC-12 cell differentiation via TrkA downstream pathways and caused the loss of hippocampal neurons in BALB/c mice. Journal of hazardous materials. vol 422. 2021-12-06. PMID:34419847. |
h&e staining of brain showed neurons in dg and ca1 areas of hippocampus decreased after bde-47 exposure. |
2021-12-06 |
2023-08-13 |
mouse |
| Sandra De la Torre-Iturbe, Rubén Antonio Vázquez-Roque, Fidel de la Cruz-López, Gonzalo Flores, Linda Garcés-Ramíre. Dendritic and behavioral changes in rats neonatally treated with homocysteine; A proposal as an animal model to study the attention deficit hyperactivity disorder. Journal of chemical neuroanatomy. 2021-12-06. PMID:34871732. |
morphological changes were found mainly in the shape of dendritic spines in the prefrontal cortex (pfc-3), dorsal hippocampus (ca1), dentate gyrus (dg) and nucleus accumbens (nacc), in rats administered neonatally with homocysteine at both ages studied. |
2021-12-06 |
2023-08-13 |
rat |
| Barna Dudok, Miklos Szoboszlay, Anirban Paul, Peter M Klein, Zhenrui Liao, Ernie Hwaun, Gergely G Szabo, Tristan Geiller, Bert Vancura, Bor-Shuen Wang, Sam McKenzie, Jesslyn Homidan, Lianne M F Klaver, Daniel F English, Z Josh Huang, György Buzsáki, Attila Losonczy, Ivan Soltes. Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior. Neuron. vol 109. issue 23. 2021-12-05. PMID:34648750. |
we achieved cell-type-specific genetic access to aacs in mice and show that aacs in the hippocampal area ca1 are synchronously activated by episodes of locomotion or whisking during rest. |
2021-12-05 |
2023-08-13 |
mouse |
| Nan Li, Kewei Xiao, Xue Mi, Na Li, Li Guo, Xiaorong Wang, Yuxiang Sun, Guo-Dong Li, Yu Zho. Ghrelin signaling in dCA1 suppresses neuronal excitability and impairs memory acquisition via PI3K/Akt/GSK-3β cascades. Neuropharmacology. vol 203. 2021-12-03. PMID:34742928. |
here, we report that micro-infusion of ghrelin in the ca1 region of the dorsal hippocampus during training specifically impairs memory acquisition. |
2021-12-03 |
2023-08-13 |
Not clear |
| Yinxian Wen, Siyuan Cheng, Juan Lu, Xia He, Zhexiao Jiao, Dan Xu, Hui Wan. Dysfunction of the hypothalamic‑pituitary‑adrenal axis in male rat offspring with prenatal food restriction: Fetal programming of hypothalamic hyperexcitability and poor hippocampal feedback. Molecular medicine reports. vol 25. issue 1. 2021-12-03. PMID:34796908. |
however, the mrna expression levels of both mr and gr in the pfr rats were higher compared with those of the control after ucs, which was accompanied histopathological changes in the dentate gyrus, cornu ammonis (ca1) and ca3 areas. |
2021-12-03 |
2023-08-13 |
rat |
| Xiaojiao Ma, Oumei Cheng, Qingsong Jiang, Junxia Yang, Huan Xiao, Hongmei Qi. Activation of ephrinb1/EPHB2/MAP-2/NMDAR Mediates Hippocampal Neurogenesis Promoted by Transcranial Direct Current Stimulation in Cerebral-Ischemic Mice. Neuromolecular medicine. vol 23. issue 4. 2021-12-02. PMID:33782855. |
compared with the sham mice, the model mice showed significant neuronal damage in the hippocampal ca1 region (p < 0.01), cognitive dysfunction (p < 0.01), and endogenous hippocampal neurogenesis (p < 0.01). |
2021-12-02 |
2023-08-13 |
mouse |
| Xiaojiao Ma, Oumei Cheng, Qingsong Jiang, Junxia Yang, Huan Xiao, Hongmei Qi. Activation of ephrinb1/EPHB2/MAP-2/NMDAR Mediates Hippocampal Neurogenesis Promoted by Transcranial Direct Current Stimulation in Cerebral-Ischemic Mice. Neuromolecular medicine. vol 23. issue 4. 2021-12-02. PMID:33782855. |
compared with the model mice, the tdcs mice had ameliorated pathological damage in the ca1 region (p < 0.01), improved cognitive function (p < 0.01), increased hippocampal neurogenesis (p < 0.01), and increased mrna and protein expression of ephrinb1, ephb2, map-2, and nmdar (p < 0.05). |
2021-12-02 |
2023-08-13 |
mouse |
| Celeste Yin-Chieh Wu, Alexandre Couto E Silva, Cristiane T Citadin, Garrett A Clemons, Christina H Acosta, Brianne A Knox, Mychal S Grames, Krista M Rodgers, Reggie Hui-Chao Lee, Hung Wen Li. Palmitic acid methyl ester inhibits cardiac arrest-induced neuroinflammation and mitochondrial dysfunction. Prostaglandins, leukotrienes, and essential fatty acids. vol 165. 2021-11-30. PMID:33445063. |
post-treatment with pame can enhance cortical cerebral blood flow and functional learning and memory, while inhibiting neuronal cell death in the ca1 region of the hippocampus under pathological conditions (i.e. |
2021-11-30 |
2023-08-13 |
Not clear |
| Choong Hyun Lee, Ji Hyeon Ahn, Bai Hui Chen, Dae Won Kim, Hyejin Sim, Tae-Kyeong Lee, Joon Ha Park, Moo-Ho Won, Soo Young Cho. Differences in TNF‑α and TNF‑R1 expression in damaged neurons and activated astrocytes of the hippocampal CA1 region between young and adult gerbils following transient forebrain ischemia. Molecular medicine reports. vol 24. issue 3. 2021-11-30. PMID:34212986. |
the present study compared the time‑dependent changes of tnf‑α and tnf‑r1 protein expression levels in the hippocampal subfield cornu ammonis 1 (ca1) between adult and young gerbils following transient forebrain ischemia (tfi), via western blot and immunohistochemistry analyses. |
2021-11-30 |
2023-08-13 |
Not clear |
| Kurt Laha, Mengwen Zhu, Erin Gemperline, Vinuta Rau, Lingjun Li, Michael S Fanselow, Richard Lennertz, Robert A Pearc. CPP impairs contextual learning at concentrations below those that block pyramidal neuron NMDARs and LTP in the CA1 region of the hippocampus. Neuropharmacology. vol 202. 2021-11-30. PMID:34687710. |
cpp impairs contextual learning at concentrations below those that block pyramidal neuron nmdars and ltp in the ca1 region of the hippocampus. |
2021-11-30 |
2023-08-13 |
Not clear |
| Yuya Sakimoto, Paw Min-Thein Oo, Makoto Goshima, Itsuki Kanehisa, Yutaro Tsukada, Dai Mitsushim. Significance of GABA International journal of molecular sciences. vol 22. issue 22. 2021-11-30. PMID:34830337. |
long-term strengthening of glutamatergic transmission is a mechanism of contextual learning in the dorsal cornu ammonis 1 (ca1) area of the hippocampus. |
2021-11-30 |
2023-08-13 |
Not clear |
| Michael Ntim, Qi-Fa Li, Yue Zhang, Xiao-Da Liu, Na Li, Hai-Lun Sun, Xuan Zhang, Bakhtawar Khan, Bin Wang, Qiong Wu, Xue-Fei Wu, Williams Walana, Khizar Khan, Quan-Hong Ma, Jie Zhao, Shao L. TRIM32 Deficiency Impairs Synaptic Plasticity by Excitatory-Inhibitory Imbalance via Notch Pathway. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 8. 2021-11-29. PMID:32219328. |
our electrophysiological studies using hippocampal slices revealed that long-term potentiation of ca1 synapses was impaired in trim32 deficient (ko) mice. |
2021-11-29 |
2023-08-13 |
mouse |
| Xia Liang, Li-Ming Hsu, Hanbing Lu, Jessica A Ash, Peter R Rapp, Yihong Yan. Functional Connectivity of Hippocampal CA3 Predicts Neurocognitive Aging via CA1-Frontal Circuit. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 8. 2021-11-29. PMID:32239141. |
the ca3 and ca1 principal cell fields of the hippocampus are vulnerable to aging, and age-related dysfunction in ca3 may be an early seed event closely linked to individual differences in memory decline. |
2021-11-29 |
2023-08-13 |
rat |
| Alen V Eapen, Diego Fernández-Fernández, John Georgiou, Zuner A Bortolotto, Stafford Lightman, David E Jane, Arturas Volianskis, Graham L Collingridg. Multiple roles of GluN2D-containing NMDA receptors in short-term potentiation and long-term potentiation in mouse hippocampal slices. Neuropharmacology. vol 201. 2021-11-27. PMID:34637787. |
in this study, we have used a glun2c/2d selective competitive antagonist, ubp145, in combination with a glun2d global knockout (glun2d ko) mouse line to study the contribution of glun2d-containing nmdars to short-term potentiation (stp) and long-term potentiation (ltp) in the ca1 region of mouse hippocampal slices. |
2021-11-27 |
2023-08-13 |
mouse |
| Brendan M Hasz, A David Redis. Spatial encoding in dorsomedial prefrontal cortex and hippocampus is related during deliberation. Hippocampus. vol 30. issue 11. 2021-11-26. PMID:32809246. |
also, reward encoding in dmpfc increased during hippocampal theta cycles where ca1 ensembles represented the goal location. |
2021-11-26 |
2023-08-13 |
rat |