| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Shi, Yuanyuan Li, Yi Zhang, Jie Chen, Jianqing Gao, Tianyuan Zhang, Xiaoguang Shang, Xiangnan Zhan. Baicalein Ameliorates Aβ-Induced Memory Deficits and Neuronal Atrophy Frontiers in pharmacology. vol 12. 2021-12-30. PMID:34966284. |
the results suggested that microinjected of aβ into ca1 of hippocampus induced cognitive and memory impairment in mice, as evidenced by decreased recognition index in the novel object recognition (nor) task, impaired memory acquisition, retention and retrieval in the morris water maze (mwm) and shuttle box tests. |
2021-12-30 |
2023-08-13 |
mouse |
| Mahesh Shivarama Shetty, Laurence Ris, Roland F R Schindler, Keiko Mizuno, Laura Fedele, Karl Peter Giese, Thomas Brand, Ted Abe. Mice Lacking the cAMP Effector Protein POPDC1 Show Enhanced Hippocampal Synaptic Plasticity. Cerebral cortex (New York, N.Y. : 1991). 2021-12-22. PMID:34937090. |
acute hippocampal slices from popdc1 knockout (ko) mice exhibit pka-dependent enhancement in ca1 long-term potentiation (ltp) in response to weaker stimulation paradigms, which in slices from wild-type mice induce only transient ltp. |
2021-12-22 |
2023-08-13 |
mouse |
| Anupratap Tomar, Thomas J McHug. The impact of stress on the hippocampal spatial code. Trends in neurosciences. 2021-12-17. PMID:34916083. |
emerging data suggest that chronic stress disrupts the acuity and specificity of ca1 spatial coding, both in familiar and novel contexts, and alters hippocampal oscillations. |
2021-12-17 |
2023-08-13 |
Not clear |
| Étienne Gervais, Parisa Iloun, Ekaterina Martianova, Ana Claudia Gonçalves Bessa, Serge Rivest, Lisa Topolni. Structural analysis of the microglia-interneuron interactions in the CA1 hippocampal area of the APP/PS1 mouse model of Alzheimer's disease. The Journal of comparative neurology. 2021-12-17. PMID:34919273. |
structural analysis of the microglia-interneuron interactions in the ca1 hippocampal area of the app/ps1 mouse model of alzheimer's disease. |
2021-12-17 |
2023-08-13 |
mouse |
| Étienne Gervais, Parisa Iloun, Ekaterina Martianova, Ana Claudia Gonçalves Bessa, Serge Rivest, Lisa Topolni. Structural analysis of the microglia-interneuron interactions in the CA1 hippocampal area of the APP/PS1 mouse model of Alzheimer's disease. The Journal of comparative neurology. 2021-12-17. PMID:34919273. |
here, we compared the interactions between microglia and parvalbumin (pv+) and somatostatin (som+) expressing interneurons in the ca1 hippocampal area of app/ps1 transgenic mice that mimic certain aspects of the alzheimer's disease (ad). |
2021-12-17 |
2023-08-13 |
mouse |
| Karine Ramires Lima, Ana Carolina de Souza da Rosa, Steffanie Severo Picua, Shara Souza E Silva, Náthaly Marks Soares, Pâmela Billig Mello-Carpe. Novelty promotes recognition memory persistence by D1 dopamine receptor and protein kinase A (PKA) signaling in rat hippocampus. The European journal of neuroscience. 2021-12-14. PMID:34904283. |
animals with infusion cannulae inserted into the ca1 hippocampus area were trained on the novel object recognition (nor) task, which involved exploring two different objects. |
2021-12-14 |
2023-08-13 |
rat |
| Alejandra Arias-Cavieres, Ateh Fonteh, Carolina I Castro-Rivera, Alfredo J Garci. Intermittent Hypoxia causes targeted disruption to NMDA receptor dependent synaptic plasticity in area CA1 of the hippocampus. Experimental neurology. vol 344. 2021-12-12. PMID:34256046. |
intermittent hypoxia causes targeted disruption to nmda receptor dependent synaptic plasticity in area ca1 of the hippocampus. |
2021-12-12 |
2023-08-13 |
mouse |
| Yukitoshi Izumi, Anil G Cashikar, Kathiresan Krishnan, Steven M Paul, Douglas F Covey, Steven J Mennerick, Charles F Zorumsk. A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 49. 2021-12-12. PMID:34725187. |
here, we examined the effects of lipopolysaccharide (lps), an activator of innate immunity, on 25hc production in microglia, and the effects of lps and 25hc on ca1 hippocampal synaptic plasticity and learning. |
2021-12-12 |
2023-08-13 |
Not clear |
| Abigail J Smith, Reagan Farmer, Katy Pilarzyk, Latarsha Porcher, Michy P Kell. A genetic basis for friendship? Homophily for membrane-associated PDE11A-cAMP-CREB signaling in CA1 of hippocampus dictates mutual social preference in male and female mice. Molecular psychiatry. 2021-12-11. PMID:34321593. |
stereotactic delivery of an isolated pde11a gaf-b domain to the mouse hippocampus revealed the membrane-associated pool of pde11a-camp-creb signaling specifically within the ca1 subfield of hippocampus is most critical for regulating social preference. |
2021-12-11 |
2023-08-13 |
mouse |
| Suresh Konakanchi, Venkateswarlu Raavi, Harendra Kumar Ml, Vinutha Shankar M. Effect of chronic sleep deprivation and sleep recovery on hippocampal CA3 neurons, spatial memory and anxiety-like behavior in rats. Neurobiology of learning and memory. vol 187. 2021-12-11. PMID:34808338. |
several studies have reported the effects of sleep deprivation on ca1 and dentate gyrus regions of the hippocampus; in contrast, there is less known about the impact of chronic sleep deprivation (csd) and sleep recovery on ca3 neurons and behavior. |
2021-12-11 |
2023-08-13 |
rat |
| Chen Chen, Junfeng Lu, Weijia Peng, Marvin Sh Mak, Yang Yang, Zeyu Zhu, Shuyi Wang, Jiawei Hou, Xin Zhou, Wenjun Xin, Yafang Hu, Karl Wah Keung Tsim, Yifan Han, Qinyu Liu, Rongbiao P. Acrolein, an endogenous aldehyde induces Alzheimer's disease-like pathologies in mice: A new sporadic AD animal model. Pharmacological research. vol 175. 2021-12-11. PMID:34838693. |
1) olfactory dysfunctions, cognitive impairments and psychological symptoms in c57bl/6 mice; 2) increased levels of aβ1-42 and tau phosphorylation (s396/t231) in cortex and hippocampus; 3) astrocytes and microglia proliferation; 4) reduced levels of postsynaptic density 95(psd95) and synapsin1, as well as the density of dendritic spines in the ca1 and dg neurons of the hippocampus; 5) high-frequency stimulation failed to induce the long-term potentiation (ltp) in the hippocampus after exposure to acrolein for 4 weeks; 6) decreased blood oxygen level-dependent (bold) signal in the olfactory bulb and induced high t2 signals in the hippocampus, which matched to the clinical observation in the brain of ad patients, and 7) activated rhoa/rock2/ p-cofilin-associated pathway in hippocampus of acrolein-treated mice, which may be the causes of synaptic damage and neuroinflammation in acrolein mice model. |
2021-12-11 |
2023-08-13 |
mouse |
| Liangliang Zhang, Wei Liang, Yiling Li, Jie Yan, Jingwen Xue, Qinyue Guo, Lan Gao, Hao Li, Qindong Sh. Mild therapeutic hypothermia improves neurological outcomes in a rat model of cardiac arrest. Brain research bulletin. vol 173. 2021-12-09. PMID:34022286. |
neuronal injury and apoptosis in the ca1 region of the hippocampus, assessed using neun immunofluorescence and terminal deoxynucleotidyl transferase-mediated dutp nick-end labeling assays, were significantly reduced in the hypothermia group 1 week after ca. |
2021-12-09 |
2023-08-13 |
rat |
| Ruike Wang, Zuntao Wu, Mengchen Liu, Yingying Wu, Qiong Li, Yue Ba, Huizhen Zhang, Xuemin Cheng, Guoyu Zhou, Hui Huan. Resveratrol reverses hippocampal synaptic markers injury and SIRT1 inhibition against developmental Pb exposure. Brain research. vol 1767. 2021-12-09. PMID:34175265. |
the dg, ca1 and ca3 regions of the hippocampus showed a considerable increase in the expression of pre- and postsynaptic proteins (p < 0.001 vs 0.2% pb group). |
2021-12-09 |
2023-08-13 |
rat |
| Jehoon Lee, Vishal Naik, Marcus Orzabal, Raine Lunde-Young, Jayanth Ramados. Morphological alteration in rat hippocampal neuronal dendrites following chronic binge prenatal alcohol exposure. Brain research. vol 1768. 2021-12-09. PMID:34297994. |
pae increased dendritic arborization and complexities of ca1, ca2/3, and dg neurons in the pnd 10 rat hippocampus. |
2021-12-09 |
2023-08-13 |
rat |
| Francesca Romana Rizzo, Livia Guadalupi, Krizia Sanna, Valentina Vanni, Diego Fresegna, Francesca De Vito, Alessandra Musella, Silvia Caioli, Sara Balletta, Silvia Bullitta, Antonio Bruno, Ettore Dolcetti, Mario Stampanoni Bassi, Fabio Buttari, Luana Gilio, Georgia Mandolesi, Diego Centonze, Antonietta Gentil. Exercise protects from hippocampal inflammation and neurodegeneration in experimental autoimmune encephalomyelitis. Brain, behavior, and immunity. vol 98. 2021-12-09. PMID:34391817. |
indeed, exercise significantly reduced microgliosis in the ca1 area, the expression of tumour necrosis factor (tnf) in microglia and, to a lesser extent, the hippocampal level of interleukin 1 beta (il-1β), previously shown to contribute to aberrant synaptic plasticity in the eae hippocampus. |
2021-12-09 |
2023-08-13 |
mouse |
| Robert Numa. The Prefrontal-Hippocampal Comparator: Volition and Episodic Memory. Perceptual and motor skills. vol 128. issue 6. 2021-12-09. PMID:34424092. |
the self-referential component of episodic memory in humans is mediated by the corollary discharge (the efference copy of the action plan developed by prefrontal cortex and transmitted to hippocampus where it is stored as a working memory; ca1 uses this efference copy to compare the expected consequences of action to the actual consequences of action). |
2021-12-09 |
2023-08-13 |
Not clear |
| Akila Pai, Lara V Marcuse, Judy Alper, Bradley N Delman, John W Rutland, Rebecca E Feldman, Patrick R Hof, Madeline Fields, James Young, Priti Balchandan. Detection of Hippocampal Subfield Asymmetry at 7T With Automated Segmentation in Epilepsy Patients With Normal Clinical Strength MRIs. Frontiers in neurology. vol 12. 2021-12-07. PMID:34867703. |
in this study, we present a novel application of the automated segmentation of hippocampal subfields (ashs) software to determine subfield volumes of the ca1, ca2/3, ca4/dg, and the subiculum using ultra high-field 7t mri scans, including t1-weighted mp2rage and t2-tse sequences, in 27 patients with either mesial temporal lobe epilepsy (mtle) or neocortical epilepsy (ne) compared to age and gender matched healthy controls. |
2021-12-07 |
2023-08-13 |
Not clear |
| Dongmeng Liu, Dahui Xue, Wencan Lu, Zhuochun Yang, Li Li, Beibei Xia, Jinhua Wei, Xianxiong Chen, Yi Yang, Xiaomei Wang, Guimiao Li. BDE-47 induced PC-12 cell differentiation via TrkA downstream pathways and caused the loss of hippocampal neurons in BALB/c mice. Journal of hazardous materials. vol 422. 2021-12-06. PMID:34419847. |
h&e staining of brain showed neurons in dg and ca1 areas of hippocampus decreased after bde-47 exposure. |
2021-12-06 |
2023-08-13 |
mouse |
| Sandra De la Torre-Iturbe, Rubén Antonio Vázquez-Roque, Fidel de la Cruz-López, Gonzalo Flores, Linda Garcés-Ramíre. Dendritic and behavioral changes in rats neonatally treated with homocysteine; A proposal as an animal model to study the attention deficit hyperactivity disorder. Journal of chemical neuroanatomy. 2021-12-06. PMID:34871732. |
morphological changes were found mainly in the shape of dendritic spines in the prefrontal cortex (pfc-3), dorsal hippocampus (ca1), dentate gyrus (dg) and nucleus accumbens (nacc), in rats administered neonatally with homocysteine at both ages studied. |
2021-12-06 |
2023-08-13 |
rat |
| Barna Dudok, Miklos Szoboszlay, Anirban Paul, Peter M Klein, Zhenrui Liao, Ernie Hwaun, Gergely G Szabo, Tristan Geiller, Bert Vancura, Bor-Shuen Wang, Sam McKenzie, Jesslyn Homidan, Lianne M F Klaver, Daniel F English, Z Josh Huang, György Buzsáki, Attila Losonczy, Ivan Soltes. Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior. Neuron. vol 109. issue 23. 2021-12-05. PMID:34648750. |
we achieved cell-type-specific genetic access to aacs in mice and show that aacs in the hippocampal area ca1 are synchronously activated by episodes of locomotion or whisking during rest. |
2021-12-05 |
2023-08-13 |
mouse |