Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Nan Li, Kewei Xiao, Xue Mi, Na Li, Li Guo, Xiaorong Wang, Yuxiang Sun, Guo-Dong Li, Yu Zho. Ghrelin signaling in dCA1 suppresses neuronal excitability and impairs memory acquisition via PI3K/Akt/GSK-3β cascades. Neuropharmacology. vol 203. 2021-12-03. PMID:34742928. |
here, we report that micro-infusion of ghrelin in the ca1 region of the dorsal hippocampus during training specifically impairs memory acquisition. |
2021-12-03 |
2023-08-13 |
Not clear |
Yinxian Wen, Siyuan Cheng, Juan Lu, Xia He, Zhexiao Jiao, Dan Xu, Hui Wan. Dysfunction of the hypothalamic‑pituitary‑adrenal axis in male rat offspring with prenatal food restriction: Fetal programming of hypothalamic hyperexcitability and poor hippocampal feedback. Molecular medicine reports. vol 25. issue 1. 2021-12-03. PMID:34796908. |
however, the mrna expression levels of both mr and gr in the pfr rats were higher compared with those of the control after ucs, which was accompanied histopathological changes in the dentate gyrus, cornu ammonis (ca1) and ca3 areas. |
2021-12-03 |
2023-08-13 |
rat |
Xiaojiao Ma, Oumei Cheng, Qingsong Jiang, Junxia Yang, Huan Xiao, Hongmei Qi. Activation of ephrinb1/EPHB2/MAP-2/NMDAR Mediates Hippocampal Neurogenesis Promoted by Transcranial Direct Current Stimulation in Cerebral-Ischemic Mice. Neuromolecular medicine. vol 23. issue 4. 2021-12-02. PMID:33782855. |
compared with the sham mice, the model mice showed significant neuronal damage in the hippocampal ca1 region (p < 0.01), cognitive dysfunction (p < 0.01), and endogenous hippocampal neurogenesis (p < 0.01). |
2021-12-02 |
2023-08-13 |
mouse |
Xiaojiao Ma, Oumei Cheng, Qingsong Jiang, Junxia Yang, Huan Xiao, Hongmei Qi. Activation of ephrinb1/EPHB2/MAP-2/NMDAR Mediates Hippocampal Neurogenesis Promoted by Transcranial Direct Current Stimulation in Cerebral-Ischemic Mice. Neuromolecular medicine. vol 23. issue 4. 2021-12-02. PMID:33782855. |
compared with the model mice, the tdcs mice had ameliorated pathological damage in the ca1 region (p < 0.01), improved cognitive function (p < 0.01), increased hippocampal neurogenesis (p < 0.01), and increased mrna and protein expression of ephrinb1, ephb2, map-2, and nmdar (p < 0.05). |
2021-12-02 |
2023-08-13 |
mouse |
Celeste Yin-Chieh Wu, Alexandre Couto E Silva, Cristiane T Citadin, Garrett A Clemons, Christina H Acosta, Brianne A Knox, Mychal S Grames, Krista M Rodgers, Reggie Hui-Chao Lee, Hung Wen Li. Palmitic acid methyl ester inhibits cardiac arrest-induced neuroinflammation and mitochondrial dysfunction. Prostaglandins, leukotrienes, and essential fatty acids. vol 165. 2021-11-30. PMID:33445063. |
post-treatment with pame can enhance cortical cerebral blood flow and functional learning and memory, while inhibiting neuronal cell death in the ca1 region of the hippocampus under pathological conditions (i.e. |
2021-11-30 |
2023-08-13 |
Not clear |
Choong Hyun Lee, Ji Hyeon Ahn, Bai Hui Chen, Dae Won Kim, Hyejin Sim, Tae-Kyeong Lee, Joon Ha Park, Moo-Ho Won, Soo Young Cho. Differences in TNF‑α and TNF‑R1 expression in damaged neurons and activated astrocytes of the hippocampal CA1 region between young and adult gerbils following transient forebrain ischemia. Molecular medicine reports. vol 24. issue 3. 2021-11-30. PMID:34212986. |
the present study compared the time‑dependent changes of tnf‑α and tnf‑r1 protein expression levels in the hippocampal subfield cornu ammonis 1 (ca1) between adult and young gerbils following transient forebrain ischemia (tfi), via western blot and immunohistochemistry analyses. |
2021-11-30 |
2023-08-13 |
Not clear |
Kurt Laha, Mengwen Zhu, Erin Gemperline, Vinuta Rau, Lingjun Li, Michael S Fanselow, Richard Lennertz, Robert A Pearc. CPP impairs contextual learning at concentrations below those that block pyramidal neuron NMDARs and LTP in the CA1 region of the hippocampus. Neuropharmacology. vol 202. 2021-11-30. PMID:34687710. |
cpp impairs contextual learning at concentrations below those that block pyramidal neuron nmdars and ltp in the ca1 region of the hippocampus. |
2021-11-30 |
2023-08-13 |
Not clear |
Yuya Sakimoto, Paw Min-Thein Oo, Makoto Goshima, Itsuki Kanehisa, Yutaro Tsukada, Dai Mitsushim. Significance of GABA International journal of molecular sciences. vol 22. issue 22. 2021-11-30. PMID:34830337. |
long-term strengthening of glutamatergic transmission is a mechanism of contextual learning in the dorsal cornu ammonis 1 (ca1) area of the hippocampus. |
2021-11-30 |
2023-08-13 |
Not clear |
Michael Ntim, Qi-Fa Li, Yue Zhang, Xiao-Da Liu, Na Li, Hai-Lun Sun, Xuan Zhang, Bakhtawar Khan, Bin Wang, Qiong Wu, Xue-Fei Wu, Williams Walana, Khizar Khan, Quan-Hong Ma, Jie Zhao, Shao L. TRIM32 Deficiency Impairs Synaptic Plasticity by Excitatory-Inhibitory Imbalance via Notch Pathway. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 8. 2021-11-29. PMID:32219328. |
our electrophysiological studies using hippocampal slices revealed that long-term potentiation of ca1 synapses was impaired in trim32 deficient (ko) mice. |
2021-11-29 |
2023-08-13 |
mouse |
Xia Liang, Li-Ming Hsu, Hanbing Lu, Jessica A Ash, Peter R Rapp, Yihong Yan. Functional Connectivity of Hippocampal CA3 Predicts Neurocognitive Aging via CA1-Frontal Circuit. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 8. 2021-11-29. PMID:32239141. |
the ca3 and ca1 principal cell fields of the hippocampus are vulnerable to aging, and age-related dysfunction in ca3 may be an early seed event closely linked to individual differences in memory decline. |
2021-11-29 |
2023-08-13 |
rat |
Alen V Eapen, Diego Fernández-Fernández, John Georgiou, Zuner A Bortolotto, Stafford Lightman, David E Jane, Arturas Volianskis, Graham L Collingridg. Multiple roles of GluN2D-containing NMDA receptors in short-term potentiation and long-term potentiation in mouse hippocampal slices. Neuropharmacology. vol 201. 2021-11-27. PMID:34637787. |
in this study, we have used a glun2c/2d selective competitive antagonist, ubp145, in combination with a glun2d global knockout (glun2d ko) mouse line to study the contribution of glun2d-containing nmdars to short-term potentiation (stp) and long-term potentiation (ltp) in the ca1 region of mouse hippocampal slices. |
2021-11-27 |
2023-08-13 |
mouse |
Brendan M Hasz, A David Redis. Spatial encoding in dorsomedial prefrontal cortex and hippocampus is related during deliberation. Hippocampus. vol 30. issue 11. 2021-11-26. PMID:32809246. |
also, reward encoding in dmpfc increased during hippocampal theta cycles where ca1 ensembles represented the goal location. |
2021-11-26 |
2023-08-13 |
rat |
Xiao Xiao, Ling Yong, Bingqing Jiao, Hui Yang, Chunlai Liang, Xudong Jia, Zhaoping Liu, Yaxin Sang, Yan Son. Postweaning exposure to lanthanum alters neurological behavior during early adulthood in rats. Neurotoxicology. vol 83. 2021-11-26. PMID:33359004. |
further results showed that lanthanum treatment significantly decreased plasma neurotransmitter levels of acetylcholine and norepinephrine as well as the number of neurons in the ca1 area of the hippocampus. |
2021-11-26 |
2023-08-13 |
rat |
Zahra Moradi, Zahra Rabiei, Maryam Anjomshoa, Zeinab Amini-Farsani, Vahid Massahzadeh, Samira Asgharzad. Neuroprotective effect of wild lowbush blueberry (Vaccinium angustifolium) on global cerebral ischemia/reperfusion injury in rats: Downregulation of iNOS/TNF-α and upregulation of miR-146a/miR-21 expression. Phytotherapy research : PTR. vol 35. issue 11. 2021-11-25. PMID:34580912. |
likewise, the bbe enlarged the ca1 and ca3 domains of the post-stroke pyramidal cell layers of the hippocampus. |
2021-11-25 |
2023-08-13 |
rat |
Felix Unger, Arthur Konnerth, Benedikt Zot. Population imaging of synaptically released glutamate in mouse hippocampal slices. STAR protocols. vol 2. issue 4. 2021-11-25. PMID:34816125. |
here, we describe single- and two-photon imaging of synaptically evoked glutamatergic population signals in acute hippocampal slices expressing the fluorescent glutamate sensor sf-iglusnfr.a184s in ca1 or ca3 pyramidal neurons. |
2021-11-25 |
2023-08-13 |
mouse |
Joaquín González Fuentes, Ricardo Insausti Serrano, Sandra Cebada Sánchez, Maria José Lagartos Donate, Eloy Rivas Infante, María Del Mar Arroyo Jiménez, María Del Pilar Marcos Raba. Neuropeptides in the developing human hippocampus under hypoxic-ischemic conditions. Journal of anatomy. vol 239. issue 4. 2021-11-23. PMID:34028021. |
two rostrocaudal sections of the body of the hippocampus were analysed, and the number of immunostained cells in the polymorphic layer of the dentate gyrus (dg) and the pyramidal cell layer and stratum oriens of the ca3, ca2 and ca1 fields of the hippocampus proper were quantified. |
2021-11-23 |
2023-08-13 |
human |
Bin Guo, Chan Chen, Lin Yang, Rong Zh. Effects of dexmedetomidine on postoperative cognitive function of sleep deprivation rats based on changes in inflammatory response. Bioengineered. vol 12. issue 1. 2021-11-23. PMID:34622713. |
compared with sd group, the escape latency was shortened, original platform-crossing times increased, mda content declined, sod activity rose, neurons were arranged orderly and number of nissl bodies increased in the hippocampal ca1 region, levels of il-1β, tnf-α, and il-6 in the hippocampus decreased, rac1/akt/nf-κb expressions were down-regulated, and proportion of nf-κb entering the nucleus declined in sd+dex group ( |
2021-11-23 |
2023-08-13 |
rat |
Pol Andrés-Benito, Margarita Carmona, Mónica Jordán Pirla, Benjamín Torrejón-Escribano, José Antonio Del Rio, Isidro Ferre. Dysregulated Protein Phosphorylation as Main Contributor of Granulovacuolar Degeneration at the First Stages of Neurofibrillary Tangles Pathology. Neuroscience. 2021-11-22. PMID:34757172. |
our results confirm the presence of ck1-δ, p38-p thr180/tyr182, sapk/jnk-p thr183/thr185, gsk-3α/β-p tyr279/tyr216, and gsk-3β ser9 in the cytoplasmic granules in a subset of neurons of the ca1 and ca2 subfields of the hippocampus. |
2021-11-22 |
2023-08-13 |
Not clear |
Ilektra Anagnostou, Daniel Muñoz-Mayorga, Teresa Morale. Prolactin neuroprotective action against excitotoxic insult in the hippocampus of male mice. Peptides. vol 135. 2021-11-19. PMID:33053420. |
neurodegeneration (fluoro-jade c), neuronal survival (neun) and astrogliosis (gfap) markers were identified with immunohistochemistry in the ca1, ca3 and ca4 areas of the dorsal hippocampus, as well as prl-related protein levels by western blot in the whole hippocampus 48 h after excitotoxicity. |
2021-11-19 |
2023-08-13 |
mouse |
István Mihály, Tímea Molnár, Ádám-József Berki, Réka-Barbara Bod, Károly Orbán-Kis, Zsolt Gáll, Tibor Szilágy. Short-Term Amygdala Low-Frequency Stimulation Does not Influence Hippocampal Interneuron Changes Observed in the Pilocarpine Model of Epilepsy. Cells. vol 10. issue 3. 2021-11-19. PMID:33804543. |
we aimed to depict the effect of amygdala dbs on the density of the most common interneuron types in the ca1 hippocampal subfield in the lithium-pilocarpine model of epilepsy. |
2021-11-19 |
2023-08-13 |
rat |