| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Glenthøj, R Hemmingsen, T G Bolwi. Kindling: a model for the development of tardive dyskinesia? Behavioural neurology. vol 1. issue 1. 2014-02-04. PMID:24486899. |
several experimental results link td with kindling: both conditions involve repeated stimulations, both seem to involve increased receptor responsiveness and in both conditions does depression in gaba transmission in snr (substantia nigra; pars reticulata) play an important role. |
2014-02-04 |
2023-08-12 |
Not clear |
| Matthew T Valley, Lansdale G Henderson, Samuel A Inverso, Pierre-Marie Lled. Adult neurogenesis produces neurons with unique GABAergic synapses in the olfactory bulb. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 37. 2013-12-02. PMID:24027267. |
we find that adult-born interneurons are resistant to presynaptic gaba(b)-mediated depression of gaba release compared with interneurons born just after birth that exhibit strong gaba(b) neuromodulation. |
2013-12-02 |
2023-08-12 |
mouse |
| Li Hu, Jia Liang, Shu-Ying Jin, Yan-Jing Han, Jun Lu, Ya T. [Progress of researches on mechanisms of acupuncture underlying improvement of depression in the past five years]. Zhen ci yan jiu = Acupuncture research. vol 38. issue 3. 2013-09-24. PMID:24006675. |
in the present paper, the authors summarize mechanisms of acupuncture for depression from 1) upregulating levels of monoamine neurotransmitters, gamma-aminobutyric acid, 5-ht, receptor binding, and hypothalamic neuropeptide y, beta-endorphine, and mu-receptor expression, and down-regulating hippocampal glutamate content, etc. |
2013-09-24 |
2023-08-12 |
Not clear |
| Hiroshi Mitoma, Hidehiro Mizusaw. [Autoantibodies to GAD and autoimmune-mediated neurological diseases]. Nihon rinsho. Japanese journal of clinical medicine. vol 71. issue 5. 2013-08-22. PMID:23777105. |
such a dual synaptic impairment, the depression at gaba synapses and the potentiation at glutamate synapses, would elicit a marked excitation of purkinje cells. |
2013-08-22 |
2023-08-12 |
rat |
| T Saleewong, A Srikiatkhachorn, M Maneepark, A Chonwerayuth, S Bongsebandhu-phubhakd. Quantifying altered long-term potentiation in the CA1 hippocampus. Journal of integrative neuroscience. vol 11. issue 3. 2013-07-11. PMID:22934805. |
in vitro brain slice techniques were used to investigate the effects of cortical-spreading depression and picrotoxin, an antagonist of the gamma-aminobutyric acid a (gaba(a)) receptor, on the tetanus-induced long-term potentiation of field excitatory postsynaptic potentials. |
2013-07-11 |
2023-08-12 |
Not clear |
| T Saleewong, A Srikiatkhachorn, M Maneepark, A Chonwerayuth, S Bongsebandhu-phubhakd. Quantifying altered long-term potentiation in the CA1 hippocampus. Journal of integrative neuroscience. vol 11. issue 3. 2013-07-11. PMID:22934805. |
cortical-spreading depression is involved in glutamate desensitization; on the other hand, gaba(a) antagonists could increase postsynaptic excitability. |
2013-07-11 |
2023-08-12 |
Not clear |
| Salvador Quiróz-González, Rodrigo Erick Escartín-Pérez, Francisco Paz-Bermudez, Bertha Segura-Alegría, Celia Reyes-Legorreta, José Carlos Guadarrama-Olmos, Benjamin Florán-Garduño, Ismael Jiménez-Estrad. Endogenous content and release of [(3)H]-GABA and [(3)H]-glutamate in the spinal cord of chronically undernourished rat. Neurochemical research. vol 38. issue 1. 2013-05-29. PMID:22983619. |
furthermore, we propose that the decreased content and release of gaba in undernourished animals are related to a depression in pre- and post-synaptic inhibition. |
2013-05-29 |
2023-08-12 |
rat |
| Olena Bukalo, Emilie Campanac, Dax A Hoffman, R Douglas Field. Synaptic plasticity by antidromic firing during hippocampal network oscillations. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 13. 2013-05-23. PMID:23479613. |
we find that facilitation of spontaneous spw-rs in hippocampal slices by increasing gap-junction coupling or by gaba(a)-mediated axon depolarization resulted in a reduction of synaptic strength, and electrical stimulation of axons evoked a widespread, long-lasting synaptic depression. |
2013-05-23 |
2023-08-12 |
Not clear |
| Federico Brandalise, Urs Gerber, Paola Ross. Golgi cell-mediated activation of postsynaptic GABA(B) receptors induces disinhibition of the Golgi cell-granule cell synapse in rat cerebellum. PloS one. vol 7. issue 8. 2013-04-25. PMID:22937048. |
these findings indicate that postsynaptic gaba(b) receptors are primarily responsible for the depression of ipscs. |
2013-04-25 |
2023-08-12 |
rat |
| J-P Guilloux, G Douillard-Guilloux, R Kota, X Wang, A M Gardier, K Martinowich, G C Tseng, D A Lewis, E Sibill. Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depression. Molecular psychiatry. vol 17. issue 11. 2013-04-23. PMID:21912391. |
supporting studies in mutant mice models suggest a complex mechanism of low constitutive and activity-dependent bdnf function in mdd, particularly affecting sst/npy-related gaba neurons, thus linking the neurotrophic and gaba hypotheses of depression. |
2013-04-23 |
2023-08-12 |
mouse |
| S F Dai, F Gao, X L Xu, W H Zhang, S X Song, G H Zho. Effects of dietary glutamine and gamma-aminobutyric acid on meat colour, pH, composition, and water-holding characteristic in broilers under cyclic heat stress. British poultry science. vol 53. issue 4. 2013-04-22. PMID:23130582. |
these results demonstrated that dietary gln and gaba offer a potential nutritional strategy to prevent cyclic hs-related depression in broiler meat chemical composition and quality. |
2013-04-22 |
2023-08-12 |
Not clear |
| Ai Miyamoto, Jun Hasegawa, Osamu Hoshin. Dynamic modulation of an orientation preference map by GABA responsible for age-related cognitive performance. Cognitive processing. vol 13. issue 4. 2013-04-18. PMID:22990592. |
accumulating evidence suggests that cognitive declines in old (healthy) animals could arise from depression of intracortical inhibition, for which a decreased ability to produce gaba during senescence might be responsible. |
2013-04-18 |
2023-08-12 |
Not clear |
| Ai Miyamoto, Jun Hasegawa, Osamu Hoshin. Dynamic modulation of an orientation preference map by GABA responsible for age-related cognitive performance. Cognitive processing. vol 13. issue 4. 2013-04-18. PMID:22990592. |
these simulation results may provide some insight into how the depression of intracortical inhibition due to a reduction in gaba content in the brain leads to age-related cognitive decline. |
2013-04-18 |
2023-08-12 |
Not clear |
| Pınar Yamantürk-Çelik, Yeşim Unlüçerçi, Serhan Sevgi, Seldağ Bekpinar, Lütfiye Eroğl. Nitrergic, glutamatergic and gabaergic systems in lithium toxicity. The Journal of toxicological sciences. vol 37. issue 5. 2013-03-05. PMID:23038008. |
all increased cns depression and mortality in lithium group however, no change was seen in gaba receptor agonist gaba (1,000 mg/kg, i.p.) |
2013-03-05 |
2023-08-12 |
rat |
| Jesús Q Beltrán, Rafael Gutiérre. Co-release of glutamate and GABA from single, identified mossy fibre giant boutons. The Journal of physiology. vol 590. issue 19. 2013-02-26. PMID:22711957. |
on the other hand, synaptic responses evoked by stimulation of interneuronal boutons located on the soma or on the basal dendrites of the same pyramidal cells were exclusively mediated by gaba(a) receptors, underwent frequency-dependent depression and were unaffected by mglur agonists.we here demonstrate that the simultaneous glutamatergic and gabaergic responses evoked by mf stimulation in pyramidal cells of ca3 during development have a common origin in the giant mfbs. |
2013-02-26 |
2023-08-12 |
rat |
| Daniela Felice, Olivia F O'Leary, Riccardo C Pizzo, John F Crya. Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: relevance to antidepressant action. Neuropharmacology. vol 63. issue 8. 2013-02-20. PMID:22884610. |
gaba(b) receptor antagonists have been shown to have antidepressant-like properties in animal models and thus, could represent a novel approach for the treatment of depression. |
2013-02-20 |
2023-08-12 |
mouse |
| Mariangela Chisari, Charles F Zorumski, Steven Menneric. Cross talk between synaptic receptors mediates NMDA-induced suppression of inhibition. Journal of neurophysiology. vol 107. issue 9. 2013-02-11. PMID:22279196. |
we found no evidence that specific synaptic nmdar subunits mediate depression of gaba responses. |
2013-02-11 |
2023-08-12 |
Not clear |
| Greice Caletti, Danielly B Olguins, Elis F Pedrollo, Helena M T Barros, Rosane Gome. Antidepressant effect of taurine in diabetic rats. Amino acids. vol 43. issue 4. 2013-01-31. PMID:22302366. |
because taurine is a gaba agonist and both amino acids are lower in the plasma of diabetic and depressive individuals, we hypothesize that taurine may represent a new adjuvant drug for the treatment of depression in diabetic individuals. |
2013-01-31 |
2023-08-12 |
rat |
| Sarah Biedermann, Wolfgang Weber-Fahr, Lei Zheng, Carolin Hoyer, Barbara Vollmayr, Peter Gass, Gabriele Ende, Alexander Sartoriu. Increase of hippocampal glutamate after electroconvulsive treatment: a quantitative proton MR spectroscopy study at 9.4 T in an animal model of depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 13. issue 6. 2013-01-07. PMID:21767208. |
recent evidence suggests that alterations in hippocampal glutamate and γ-aminobutyric acid (gaba) are associated with the pathomechanism of depression and treatment effects of electroconvulsive therapy (ect). |
2013-01-07 |
2023-08-12 |
Not clear |
| Bridget L Morse, Nisha Vijay, Marilyn E Morri. γ-Hydroxybutyrate (GHB)-induced respiratory depression: combined receptor-transporter inhibition therapy for treatment in GHB overdose. Molecular pharmacology. vol 82. issue 2. 2012-10-09. PMID:22561075. |
pretreatment with 150 mg/kg sch50911 completely prevented the decrease in respiratory rate, indicating agonism at gaba(b) receptors to be primarily responsible for ghb-induced respiratory depression. |
2012-10-09 |
2023-08-12 |
rat |