| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J C Hackman, A M Holohean, R A Davidof. Role of metabotropic glutamate receptors in the depression of GABA-mediated depolarization of frog primary afferent terminals. Neuroscience. vol 81. issue 4. 1997-11-26. PMID:9330369. |
increasing the intracellular concentration of 3'-5'-cyclic adenosine monophosphate with 8-bromo-camp, forskolin, and 3-isobutyl-1-methylxanthine significantly reduced gaba depolarizations, but the protein kinase inhibitors rp-adenosine 3,5-cyclic monophosphothioate triethylamine and n-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide did not alter t-acpd's depression of gaba depolarizations. |
1997-11-26 |
2023-08-12 |
Not clear |
| J C Hackman, A M Holohean, R A Davidof. Role of metabotropic glutamate receptors in the depression of GABA-mediated depolarization of frog primary afferent terminals. Neuroscience. vol 81. issue 4. 1997-11-26. PMID:9330369. |
these results suggest that t-acpd's depression of gaba depolarizations involves an indirect, three-stage mechanism that includes activation of group i metabotropic glutamate receptors on interneurons and/or on afferent terminals, the release of l-glutamate from the latter structures, and the activation of n-methyl-d-aspartate receptors on primary afferent terminals. |
1997-11-26 |
2023-08-12 |
Not clear |
| J C Hackman, A M Holohean, R A Davidof. Role of metabotropic glutamate receptors in the depression of GABA-mediated depolarization of frog primary afferent terminals. Neuroscience. vol 81. issue 4. 1997-11-26. PMID:9330369. |
the depression of gaba depolarizations caused by the release of l-glutamate from afferent terminal and/or interneurons leads to a block of presynaptic inhibition (produced in the frog spinal cord by gaba) resulting in a positive feed-forward amplification of reflex transmission. |
1997-11-26 |
2023-08-12 |
Not clear |
| M Galarreta, S Hestri. Properties of GABAA receptors underlying inhibitory synaptic currents in neocortical pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 19. 1997-10-15. PMID:9295368. |
this conclusion is based on the similar fast decay kinetics of the response to brief and prolonged pulses of gaba and on the correlation between the degree of paired-pulse depression and the decay rate of the currents induced by brief pulses. |
1997-10-15 |
2023-08-12 |
Not clear |
| F Bordi, A Reggiani, F Conque. Regulation of synaptic plasticity by mGluR1 studied in vivo in mGluR1 mutant mice. Brain research. vol 761. issue 1. 1997-10-01. PMID:9247074. |
the gaba(b) agonist baclofen, acting presynaptically on the gaba interneurons, attenuated paired-pulse depression and allowed for a normal and stable ltp in mglur1 mutant mice. |
1997-10-01 |
2023-08-12 |
mouse |
| Z X Xi, T Akas. Opioid peptides modulate GABA(A) receptor responses in neurons of bullfrog dorsal root ganglia. Brain research. vol 758. issue 1-2. 1997-09-16. PMID:9203545. |
naltrindole (nti), a delta-receptor antagonist, prevented the dpdpe-induced depression of the gaba current. |
1997-09-16 |
2023-08-12 |
Not clear |
| Z X Xi, T Akas. Opioid peptides modulate GABA(A) receptor responses in neurons of bullfrog dorsal root ganglia. Brain research. vol 758. issue 1-2. 1997-09-16. PMID:9203545. |
beta-funaltrexamine (beta-fna), a mu-receptor antagonist, reduced the damgo-induced depression of gaba currents. |
1997-09-16 |
2023-08-12 |
Not clear |
| S Wang, J M Wojtowic. Effect of GABA(B) receptors on synaptic interactions in dentate gyrus granule neurons of the rat. Neuroscience. vol 79. issue 1. 1997-08-04. PMID:9178869. |
presynaptically, gaba(b) receptors produced a short-lasting heterosynaptic depression in the medial pathway, which was reduced by cgp36742. |
1997-08-04 |
2023-08-12 |
rat |
| S Delpierre, Y Jamme. GABA(B) receptor blockade reduces resistive loading-induced hypoventilation in anesthetized rabbits. Neuroscience letters. vol 226. issue 2. 1997-07-29. PMID:9159495. |
in that case, ventilatory depression should be minimized by gaba(b) receptor blockade. |
1997-07-29 |
2023-08-12 |
Not clear |
| S Arakawa, S Nakamura, N Kawashima, S Nishiike, Y Fuji. Antidromic burst activity of locus coeruleus neurons during cortical spreading depression. Neuroscience. vol 78. issue 4. 1997-07-22. PMID:9174080. |
the antidromic burst activity of locus coeruleus neurons also appeared for a short time during cortical spreading depression prior to the occurrence of seizure waves induced by gaba antagonists, while the burst activity could not be observed during seizure activity. |
1997-07-22 |
2023-08-12 |
rat |
| Z X Xi, K Yamada, M Tsurusaki, T Akas. Baclofen reduces GABAA receptor responses in acutely dissociated neurons of bullfrog dorsal root ganglia. Synapse (New York, N.Y.). vol 26. issue 2. 1997-07-18. PMID:9131775. |
baclofen produced an irreversible depression of the gaba current in neurons dialyzed with an internal solution containing guanosine 5'-o-(3-thiotriphosphate) (gtp gamma s, 100 microm). |
1997-07-18 |
2023-08-12 |
Not clear |
| Z X Xi, K Yamada, M Tsurusaki, T Akas. Baclofen reduces GABAA receptor responses in acutely dissociated neurons of bullfrog dorsal root ganglia. Synapse (New York, N.Y.). vol 26. issue 2. 1997-07-18. PMID:9131775. |
the baclofen-induced depression of the gaba current was blocked by pki(5-24), a specific pka inhibitor, but not by pkc(19-36), a specific protein kinase c (pkc) inhibitor. |
1997-07-18 |
2023-08-12 |
Not clear |
| K Obrietan, A N van den Po. GABA activity mediating cytosolic Ca2+ rises in developing neurons is modulated by cAMP-dependent signal transduction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 12. 1997-06-30. PMID:9169537. |
postsynaptic depression of gaba-evoked ca2+ rises triggered by h89 (in the presence of ttx) recovered rapidly, suggesting that the extended depression observed during synaptic gaba release was largely through a presynaptic mechanism. |
1997-06-30 |
2023-08-12 |
Not clear |
| T Akasu, K Yamad. Neurokinin-1 (NK1) receptors mediate tachykinin-induced depression of GABA current in bullfrog sensory neurons. The Kurume medical journal. vol 44. issue 1. 1997-06-19. PMID:9154760. |
neurokinin-1 (nk1) receptors mediate tachykinin-induced depression of gaba current in bullfrog sensory neurons. |
1997-06-19 |
2023-08-12 |
Not clear |
| T Akasu, K Yamad. Neurokinin-1 (NK1) receptors mediate tachykinin-induced depression of GABA current in bullfrog sensory neurons. The Kurume medical journal. vol 44. issue 1. 1997-06-19. PMID:9154760. |
cp99994 (1 microm), an neurokinin-1 (nk1) receptor antagonist, inhibited the substance p-induced depression of the gaba current. |
1997-06-19 |
2023-08-12 |
Not clear |
| B J Krishek, S J Moss, T G Smar. A functional comparison of the antagonists bicuculline and picrotoxin at recombinant GABAA receptors. Neuropharmacology. vol 35. issue 9-10. 1997-05-12. PMID:9014144. |
gaba equilibrium concentration-response curves for each receptor construct were shifted to the right by increasing concentrations of bicuculline in a competitive manner, whereas picrotoxin induced a slight lateral shift as well as a depression of the maximum response consistent with a mixed/non-competitive inhibitory mechanism. |
1997-05-12 |
2023-08-12 |
xenopus_laevis |
| P L Lutz, G E Nilsso. Contrasting strategies for anoxic brain survival--glycolysis up or down. The Journal of experimental biology. vol 200. issue Pt 2. 1997-04-15. PMID:9050250. |
brain metabolic depression is brought about by activating channel arrest to reduce ion flux and through the release of inhibitory gamma-aminobutyric acid (gaba) and the upregulation of gabaa receptors. |
1997-04-15 |
2023-08-12 |
Not clear |
| A Reipschläger, G E Nilsson, H O Pörtne. A role for adenosine in metabolic depression in the marine invertebrate Sipunculus nudus. The American journal of physiology. vol 272. issue 1 Pt 2. 1997-03-31. PMID:9039028. |
among amino acids (gamma-aminobutyric acid, glutamate, glycine, taurine, serine, and aspartate) and monoamines (serotonin, dopamine, and norepinephrine), some changes were significant, but none were consistent with metabolic depression under all experimental conditions applied. |
1997-03-31 |
2023-08-12 |
Not clear |
| Y Wang, C H Jeng, Y S Chai, Y R Lee, J C Li. Electrophysiological and electrochemical responses of NMDA in the cerebellum: interactions with nonadrenergic pathway. Neuropharmacology. vol 35. issue 6. 1997-03-05. PMID:9045074. |
in contrast, the depression induced by gaba, which did not induce ne overflow, was not potentiated by phenoxybenzamine. |
1997-03-05 |
2023-08-12 |
rat |
| Y Wang, C H Jeng, J C Lin, J Y Wan. Serotonin modulates ethanol-induced depression in cerebellar Purkinje neurons. Alcoholism, clinical and experimental research. vol 20. issue 7. 1997-03-03. PMID:8904976. |
5-ht also potentiated depressions induced by gamma-aminobutyric acid; however, this modulatory response was quantitatively smaller than 5-ht-induced potentiation of ethanol depression. |
1997-03-03 |
2023-08-12 |
rat |