| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shyamal H Mehta, Robert J Adam. Treatment and prevention of stroke in children with sickle cell disease. Current treatment options in neurology. vol 8. issue 6. 2011-07-14. PMID:17032571. |
stroke is one of the major complications in children with sickle cell disease (scd). |
2011-07-14 |
2023-08-12 |
Not clear |
| Shyamal H Mehta, Robert J Adam. Treatment and prevention of stroke in children with sickle cell disease. Current treatment options in neurology. vol 8. issue 6. 2011-07-14. PMID:17032571. |
there have been no acute stroke treatment studies in scd, but hydration and exchange transfusion are often recommended. |
2011-07-14 |
2023-08-12 |
Not clear |
| Shyamal H Mehta, Robert J Adam. Treatment and prevention of stroke in children with sickle cell disease. Current treatment options in neurology. vol 8. issue 6. 2011-07-14. PMID:17032571. |
tcd screening of all children with scd, and initiation and maintenance of chronic transfusion to maintain hemoglobin s below 30% in the high-risk group, is the only proven prevention strategy for stroke in scd. |
2011-07-14 |
2023-08-12 |
Not clear |
| Shyamal H Mehta, Robert J Adam. Treatment and prevention of stroke in children with sickle cell disease. Current treatment options in neurology. vol 8. issue 6. 2011-07-14. PMID:17032571. |
bone marrow transplantation can be curative for scd, and limited data support its use to prevent stroke in scd. |
2011-07-14 |
2023-08-12 |
Not clear |
| William J Savage, Allen D Everett, James F Casell. Plasma glial fibrillary acidic protein levels in a child with sickle cell disease and stroke. Acta haematologica. vol 125. issue 3. 2011-05-06. PMID:21099215. |
a 12-year-old boy with hbss sickle cell disease (scd) was admitted with an acute febrile illness and developed overt stroke 3 days later. |
2011-05-06 |
2023-08-12 |
Not clear |
| William J Savage, Allen D Everett, James F Casell. Plasma glial fibrillary acidic protein levels in a child with sickle cell disease and stroke. Acta haematologica. vol 125. issue 3. 2011-05-06. PMID:21099215. |
stroke in scd can occur in the setting of acute illness, and a biomarker that could predict the onset and triage ill children to therapeutic intervention more quickly would be useful. |
2011-05-06 |
2023-08-12 |
Not clear |
| Monica L Hulbert, Robert C McKinstry, JoAnne L Lacey, Christopher J Moran, Julie A Panepinto, Alexis A Thompson, Sharada A Sarnaik, Gerald M Woods, James F Casella, Baba Inusa, Jo Howard, Fenella J Kirkham, Kofi A Anie, Jonathan E Mullin, Rebecca Ichord, Michael Noetzel, Yan Yan, Mark Rodeghier, Michael R Debau. Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease. Blood. vol 117. issue 3. 2011-04-14. PMID:20940417. |
children with sickle cell disease (scd) and strokes receive blood transfusion therapy for secondary stroke prevention; despite this, approximately 20% experience second overt strokes. |
2011-04-14 |
2023-08-12 |
Not clear |
| Monica L Hulbert, Robert C McKinstry, JoAnne L Lacey, Christopher J Moran, Julie A Panepinto, Alexis A Thompson, Sharada A Sarnaik, Gerald M Woods, James F Casella, Baba Inusa, Jo Howard, Fenella J Kirkham, Kofi A Anie, Jonathan E Mullin, Rebecca Ichord, Michael Noetzel, Yan Yan, Mark Rodeghier, Michael R Debau. Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease. Blood. vol 117. issue 3. 2011-04-14. PMID:20940417. |
given this rate of second overt strokes and the clinical significance of silent cerebral infarcts, we tested the hypothesis that silent cerebral infarcts occur among children with scd being transfused for secondary stroke prevention. |
2011-04-14 |
2023-08-12 |
Not clear |
| Monica L Hulbert, Robert C McKinstry, JoAnne L Lacey, Christopher J Moran, Julie A Panepinto, Alexis A Thompson, Sharada A Sarnaik, Gerald M Woods, James F Casella, Baba Inusa, Jo Howard, Fenella J Kirkham, Kofi A Anie, Jonathan E Mullin, Rebecca Ichord, Michael Noetzel, Yan Yan, Mark Rodeghier, Michael R Debau. Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease. Blood. vol 117. issue 3. 2011-04-14. PMID:20940417. |
a prospective cohort enrolled children with scd and overt strokes at 7 academic centers. |
2011-04-14 |
2023-08-12 |
Not clear |
| Monica L Hulbert, Robert C McKinstry, JoAnne L Lacey, Christopher J Moran, Julie A Panepinto, Alexis A Thompson, Sharada A Sarnaik, Gerald M Woods, James F Casella, Baba Inusa, Jo Howard, Fenella J Kirkham, Kofi A Anie, Jonathan E Mullin, Rebecca Ichord, Michael Noetzel, Yan Yan, Mark Rodeghier, Michael R Debau. Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease. Blood. vol 117. issue 3. 2011-04-14. PMID:20940417. |
children with scd and overt strokes receiving regular blood transfusion therapy experience silent cerebral infarcts at a higher rate than previously recognized. |
2011-04-14 |
2023-08-12 |
Not clear |
| Monica L Hulbert, Robert C McKinstry, JoAnne L Lacey, Christopher J Moran, Julie A Panepinto, Alexis A Thompson, Sharada A Sarnaik, Gerald M Woods, James F Casella, Baba Inusa, Jo Howard, Fenella J Kirkham, Kofi A Anie, Jonathan E Mullin, Rebecca Ichord, Michael Noetzel, Yan Yan, Mark Rodeghier, Michael R Debau. Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease. Blood. vol 117. issue 3. 2011-04-14. PMID:20940417. |
additional therapies are needed for secondary stroke prevention in children with scd. |
2011-04-14 |
2023-08-12 |
Not clear |
| M Arkuszewski, E R Melhem, J Krejz. Neuroimaging in assessment of risk of stroke in children with sickle cell disease. Advances in medical sciences. vol 55. issue 2. 2011-04-08. PMID:21109500. |
stroke and subclinical "silent infarcts" are major causes of morbidity in children with sickle cell disease (scd). |
2011-04-08 |
2023-08-12 |
Not clear |
| Pramil Cheriyath, Fan He, Ian Peters, Xian Li, Peter Alagona, Chuntao Wu, Min Pu, Wayne E Cascio, Duanping Lia. Relation of atrial and/or ventricular premature complexes on a two-minute rhythm strip to the risk of sudden cardiac death (the Atherosclerosis Risk in Communities [ARIC] study). The American journal of cardiology. vol 107. issue 2. 2011-04-05. PMID:21211594. |
in this study, we examined the prospective relation between baseline vpcs or apcs and scd, myocardial infarction, and fatal coronary heart disease (chd) in a population-based sample of subjects from the atherosclerosis risk in communities (aric) study excluding participants with known history of chd or stroke. |
2011-04-05 |
2023-08-12 |
human |
| Banu Aygun, Jennifer Parker, Molly B Freeman, Alexis L Stephens, Matthew P Smeltzer, Song Wu, Jane S Hankins, Winfred C Wan. Neurocognitive screening with the Brigance preschool screen-II in 3-year-old children with sickle cell disease. Pediatric blood & cancer. vol 56. issue 4. 2011-03-24. PMID:21298749. |
neurocognitive deficits have been described in school age children with sickle cell disease (scd), even in the absence of stroke or silent infarcts. |
2011-03-24 |
2023-08-12 |
Not clear |
| Elsie Gyang, Kristen Yeom, Carolyn Hoppe, Sonia Partap, Michael Jen. Effect of chronic red cell transfusion therapy on vasculopathies and silent infarcts in patients with sickle cell disease. American journal of hematology. vol 86. issue 1. 2011-02-11. PMID:21117059. |
regular, chronic red cell transfusions (ctx) have been shown to be effective prophylaxis against stroke in sickle cell disease (scd) in those at risk. |
2011-02-11 |
2023-08-12 |
Not clear |
| Elsie Gyang, Kristen Yeom, Carolyn Hoppe, Sonia Partap, Michael Jen. Effect of chronic red cell transfusion therapy on vasculopathies and silent infarcts in patients with sickle cell disease. American journal of hematology. vol 86. issue 1. 2011-02-11. PMID:21117059. |
thus, we retrospectively evaluated the magnetic resonance imaging reports of a cohort of scd patients who were prescribed ctx for either primary or secondary stroke prophylaxis. |
2011-02-11 |
2023-08-12 |
Not clear |
| Zhou Zhou, Hyojeong Han, Miguel A Cruz, José A López, Jing-Fei Dong, Prasenjit Guchhai. Haemoglobin blocks von Willebrand factor proteolysis by ADAMTS-13: a mechanism associated with sickle cell disease. Thrombosis and haemostasis. vol 101. issue 6. 2010-09-17. PMID:19492149. |
vascular occlusion, thromboembolism and strokes are hallmark events in sickle cell disease (scd). |
2010-09-17 |
2023-08-12 |
Not clear |
| Ariel Koren, Daniel Fink, Osnat Admoni, Yardena Tennenbaum-Rakover, Carina Levi. Non-transferrin-bound labile plasma iron and iron overload in sickle-cell disease: a comparative study between sickle-cell disease and beta-thalassemic patients. European journal of haematology. vol 84. issue 1. 2010-05-14. PMID:19732137. |
blood transfusions are the standard of care in b thalassemia and transfusions are also indicated in sickle cell disease (scd) patients with hypersplenism, recurrent vaso-occlusive crises and for stroke prevention. |
2010-05-14 |
2023-08-12 |
Not clear |
| Michael M Dowling, Nancy Lee, Charles T Quinn, Zora R Rogers, Deborah Boger, Naveed Ahmad, Claudio Ramaciotti, George R Buchana. Prevalence of intracardiac shunting in children with sickle cell disease and stroke. The Journal of pediatrics. vol 156. issue 4. 2010-04-29. PMID:20022343. |
to determine the prevalence of potential intracardiac shunts, including patent foramen ovale (pfo), in children with sickle cell disease (scd) and stroke. |
2010-04-29 |
2023-08-12 |
Not clear |
| Heba Mourad, Wael Fadel, Manal El Batch, Mohamed Rowish. Heamostatic and genetic predisposing factors for stroke in children with sickle cell anemia. The Egyptian journal of immunology. vol 15. issue 1. 2010-04-21. PMID:20306667. |
sickle cell anemia (sca) is the most common type of scd and represents the homozygous form, in which the individual inherits a double dose of the abnormal gene that codes for hemoglobin s. this study was done to detect cases of silent and clinically overt strokes in children with sickle cell anemia (sca) and examine predisposing factors for stroke development. |
2010-04-21 |
2023-08-12 |
human |