| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Armstrong-Wells, B Grimes, S Sidney, D Kronish, S C Shiboski, R J Adams, H J Fullerto. Utilization of TCD screening for primary stroke prevention in children with sickle cell disease. Neurology. vol 72. issue 15. 2009-05-01. PMID:19365052. |
in 1998, the stroke prevention trial in sickle cell anemia showed a >90% reduction in stroke rates after blood transfusion therapy in children with sickle cell disease (scd) identified as high risk with transcranial doppler ultrasonography (tcd) screening. |
2009-05-01 |
2023-08-12 |
Not clear |
| Yu-Sok Kim, Erfan Nur, Eduard J van Beers, Jasper Truijen, Shyrin C A T Davis, Bart J Biemond, Johannes J van Lieshou. Dynamic cerebral autoregulation in homozygous Sickle cell disease. Stroke. vol 40. issue 3. 2009-03-20. PMID:19150866. |
sickle cell disease (scd) is associated with cerebral hyperperfusion and an increased risk of stroke. |
2009-03-20 |
2023-08-12 |
Not clear |
| Cynthia L Price, Michael T Johnson, Terianne Lindsay, Douglas Dalton, A R Watkins, Michael R DeBau. The Sickle Cell Sabbath: a community program increases first-time blood donors in the African American faith community. Transfusion. vol 49. issue 3. 2009-03-16. PMID:19040492. |
blood transfusion therapy is an established treatment for primary and secondary prevention of strokes in children with sickle cell disease (scd), a disease that predominantly affects african americans. |
2009-03-16 |
2023-08-12 |
Not clear |
| Jean L Raphael, Priya B Shetty, Hao Liu, Donald H Mahoney, Brigitta U Muelle. A critical assessment of transcranial doppler screening rates in a large pediatric sickle cell center: opportunities to improve healthcare quality. Pediatric blood & cancer. vol 51. issue 5. 2008-10-07. PMID:18623200. |
transcranial doppler ultrasound (tcd) has been demonstrated to be a powerful predictor of stroke risk due to sickle cell disease (scd) in pediatric populations. |
2008-10-07 |
2023-08-12 |
Not clear |
| Jeffrey I Gold, Caroline B Johnson, Marsha J Treadwell, Nitu Hans, Elliott Vichinsk. Detection and assessment of stroke in patients with sickle cell disease: neuropsychological functioning and magnetic resonance imaging. Pediatric hematology and oncology. vol 25. issue 5. 2008-08-07. PMID:18569843. |
sickle cell disease (scd) is associated with increased risk of stroke and cognitive impairment. |
2008-08-07 |
2023-08-12 |
Not clear |
| Jeffrey I Gold, Caroline B Johnson, Marsha J Treadwell, Nitu Hans, Elliott Vichinsk. Detection and assessment of stroke in patients with sickle cell disease: neuropsychological functioning and magnetic resonance imaging. Pediatric hematology and oncology. vol 25. issue 5. 2008-08-07. PMID:18569843. |
based on mri analysis, 27% of patients with scd had experienced a stroke and 13% a silent infarct. |
2008-08-07 |
2023-08-12 |
Not clear |
| Michael Wolf, Carla Cangemi, Richard Drachtman, Margaret Masterso. Primary hemorrhagic stroke in a 12-year-old female with sickle cell disease and normal transcranial Doppler. Pediatric hematology and oncology. vol 25. issue 5. 2008-08-07. PMID:18569847. |
stroke is a well-known complication of sickle cell disease (scd). |
2008-08-07 |
2023-08-12 |
Not clear |
| Swee Lay Thei. Genetic modifiers of the beta-haemoglobinopathies. British journal of haematology. vol 141. issue 3. 2008-06-27. PMID:18410570. |
since some of the complications, such as overt stroke in scd, are relatively rare events, intermediate end-points that contribute to the phenotype, such as transcranial doppler velocity (a major predictor of stroke in scd), could be integrated within the genetic analysis. |
2008-06-27 |
2023-08-12 |
Not clear |
| Cheryl A Hillery, Julie A Panepint. Pathophysiology of stroke in sickle cell disease. Microcirculation (New York, N.Y. : 1994). vol 11. issue 2. 2008-06-03. PMID:15280092. |
stroke affects both motor and cognitive function in patients with sickle cell disease (scd). |
2008-06-03 |
2023-08-12 |
Not clear |
| Cheryl A Hillery, Julie A Panepint. Pathophysiology of stroke in sickle cell disease. Microcirculation (New York, N.Y. : 1994). vol 11. issue 2. 2008-06-03. PMID:15280092. |
while the natural history of stroke in scd is well described, the pathophysiology remains poorly understood and probably varies with the site of vascular injury. |
2008-06-03 |
2023-08-12 |
Not clear |
| Allison A King, Michael R DeBaun, Desiree A Whit. Need for cognitive rehabilitation for children with sickle cell disease and strokes. Expert review of neurotherapeutics. vol 8. issue 2. 2008-04-10. PMID:18271713. |
stroke is a significant cause of morbidity among children with sickle cell disease (scd). |
2008-04-10 |
2023-08-12 |
Not clear |
| Allison A King, Michael R DeBaun, Desiree A Whit. Need for cognitive rehabilitation for children with sickle cell disease and strokes. Expert review of neurotherapeutics. vol 8. issue 2. 2008-04-10. PMID:18271713. |
ongoing studies are designed to improve the cognitive impairment for children with scd and stroke. |
2008-04-10 |
2023-08-12 |
Not clear |
| Robert J Adam. Big strokes in small persons. Archives of neurology. vol 64. issue 11. 2008-01-24. PMID:17998439. |
young children with scd are at a very high risk of stroke. |
2008-01-24 |
2023-08-12 |
Not clear |
| Robert J Adam. Big strokes in small persons. Archives of neurology. vol 64. issue 11. 2008-01-24. PMID:17998439. |
the most commonly recognized stroke syndrome in children with scd is large-artery infarction. |
2008-01-24 |
2023-08-12 |
Not clear |
| Robert J Adam. Big strokes in small persons. Archives of neurology. vol 64. issue 11. 2008-01-24. PMID:17998439. |
children with scd who are developing high stroke risk can be detected months to years before the stroke using tcd. |
2008-01-24 |
2023-08-12 |
Not clear |
| Robert J Adam. Big strokes in small persons. Archives of neurology. vol 64. issue 11. 2008-01-24. PMID:17998439. |
two independent studies have demonstrated that the risk of stroke in children with scd increases with tcd velocity. |
2008-01-24 |
2023-08-12 |
Not clear |
| Robert J Adam. Big strokes in small persons. Archives of neurology. vol 64. issue 11. 2008-01-24. PMID:17998439. |
stroke risk in all children with scd is approximately 0.5% to 1.0% per year. |
2008-01-24 |
2023-08-12 |
Not clear |
| Lakshmanan Krishnamurti, Lizabeth Lanford, Ricardo Muno. Life threatening parvovirus B19 and herpes simplex virus associated acute myocardial dysfunction in a child with homozygous sickle cell disease. Pediatric blood & cancer. vol 49. issue 7. 2007-12-06. PMID:16700044. |
however, acute splenic sequestration, acute chest syndrome, nephrotic syndrome, and stroke have been reported in scd patients following hpv b19 infection. |
2007-12-06 |
2023-08-12 |
human |
| Françoise Bernaudin, Gérard Socie, Mathieu Kuentz, Sylvie Chevret, Michel Duval, Yves Bertrand, Jean-Pierre Vannier, Karima Yakouben, Isabelle Thuret, Pierre Bordigoni, Alain Fischer, Patrick Lutz, Jean-Louis Stephan, Nathalie Dhedin, Emmanuel Plouvier, Geneviève Margueritte, Dominique Bories, Suzanne Verlhac, Hélène Esperou, Lena Coic, Jean-Paul Vernant, Eliane Gluckma. Long-term results of related myeloablative stem-cell transplantation to cure sickle cell disease. Blood. vol 110. issue 7. 2007-11-06. PMID:17606762. |
these results indicate that hla-identical sibling hsct after myeloablative conditioning with atg should be considered as a standard of care for scd children who are at high risk for stroke. |
2007-11-06 |
2023-08-12 |
Not clear |
| Melissa Creary, Dhelia Williamson, Roshni Kulkarn. Sickle cell disease: current activities, public health implications, and future directions. Journal of women's health (2002). vol 16. issue 5. 2007-10-19. PMID:17627395. |
although there has been extensive clinical and basic science research in scd, many public health issues, such as blood safety surveillance, compliance with immunizations, follow-up of newborns with positive screening tests, stroke prevention, pregnancy complications, pain prevention, quality of life, and thrombosis, in people with sct remain unaddressed. |
2007-10-19 |
2023-08-12 |
Not clear |