Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Elsa Mirre, Valentine Brousse, Laureline Berteloot, Karen Lambot-Juhan, Suzanne Verlhac, Claire Boulat, Marie-Dominique Dumont, Gérard Lenoir, Mariane de Montalember. Feasibility and efficacy of chronic transfusion for stroke prevention in children with sickle cell disease. European journal of haematology. vol 84. issue 3. 2010-03-26. PMID:19912310. |
in children with sickle cell disease (scd), chronic transfusion to maintain haemoglobin s (hbs) below 30% markedly decreases both the risk of a first stroke when transcranial doppler (tcd) ultrasonography shows abnormal cerebral blood flow velocities and the risk of recurrent stroke. |
2010-03-26 |
2023-08-12 |
Not clear |
A Elira Dokekias, L Ngolet Ossini, F O Atipo Tsiba, F Malanda, I Koko, M De Montalember. [Blood transfusion assessment to 112 homozygous sickle-cell disease patients in university hospital of Brazzaville]. Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine. vol 16. issue 5-6. 2010-02-08. PMID:19369104. |
homozygous, sickle-cell disease (scd) is responsible for acute complication, especially anaemic crisis and special situation such as acute chest syndrome, stroke and acute priapism. |
2010-02-08 |
2023-08-12 |
Not clear |
A Elira Dokekias, L Ngolet Ossini, F O Atipo Tsiba, F Malanda, I Koko, M De Montalember. [Blood transfusion assessment to 112 homozygous sickle-cell disease patients in university hospital of Brazzaville]. Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine. vol 16. issue 5-6. 2010-02-08. PMID:19369104. |
in the second group (20 cases), scd patients have particularly situations: pregnancy (10 cases); stroke (six cases); cardiac failure (two cases) and priapism (two cases). |
2010-02-08 |
2023-08-12 |
Not clear |
Luis A Verduzco, David G Natha. Sickle cell disease and stroke. Blood. vol 114. issue 25. 2010-01-08. PMID:19797523. |
twenty-four percent of sickle cell disease (scd) patients have a stroke by the age of 45 years. |
2010-01-08 |
2023-08-12 |
Not clear |
Luis A Verduzco, David G Natha. Sickle cell disease and stroke. Blood. vol 114. issue 25. 2010-01-08. PMID:19797523. |
although viscosity is of importance in the noncerebral manifestations of scd, inflammation may play a larger role than viscosity in the development of large-vessel stroke. |
2010-01-08 |
2023-08-12 |
Not clear |
Luis A Verduzco, David G Natha. Sickle cell disease and stroke. Blood. vol 114. issue 25. 2010-01-08. PMID:19797523. |
the future of scd stroke management lies in the avoidance of transfusion. |
2010-01-08 |
2023-08-12 |
Not clear |
Luis A Verduzco, David G Natha. Sickle cell disease and stroke. Blood. vol 114. issue 25. 2010-01-08. PMID:19797523. |
recent genome-wide association studies may provide methods for modulating fetal hemoglobin production enough to attenuate stroke risk and other complications of scd. |
2010-01-08 |
2023-08-12 |
Not clear |
Erfan Nur, Yu-Sok Kim, Jasper Truijen, Eduard J van Beers, Shyrin C A T Davis, Dees P Brandjes, Bart J Biemond, Johannes J van Lieshou. Cerebrovascular reserve capacity is impaired in patients with sickle cell disease. Blood. vol 114. issue 16. 2009-11-06. PMID:19700663. |
in scd patients, impaired cerebrovascular co2 responsiveness reflects reduced cerebrovascular reserve capacity, which may play a role in pathophysiology of stroke. |
2009-11-06 |
2023-08-12 |
human |
John J Strouse, Lori C Jordan, Sophie Lanzkron, James F Casell. The excess burden of stroke in hospitalized adults with sickle cell disease. American journal of hematology. vol 84. issue 9. 2009-10-08. PMID:19623672. |
this report compares the relative rates and risk factors associated with stroke in adults versus children with sickle cell disease (scd) in the united states over the last decade. |
2009-10-08 |
2023-08-12 |
Not clear |
John J Strouse, Lori C Jordan, Sophie Lanzkron, James F Casell. The excess burden of stroke in hospitalized adults with sickle cell disease. American journal of hematology. vol 84. issue 9. 2009-10-08. PMID:19623672. |
we identified incident strokes in patients with scd using icd-9 codes for acute stroke and scd and the california patient discharge databases. |
2009-10-08 |
2023-08-12 |
Not clear |
John J Strouse, Lori C Jordan, Sophie Lanzkron, James F Casell. The excess burden of stroke in hospitalized adults with sickle cell disease. American journal of hematology. vol 84. issue 9. 2009-10-08. PMID:19623672. |
our results suggest that the rate of stroke in scd peaks in older adults and is three-fold higher than rates previously reported in african-americans of similar age (35-64 years) without scd. |
2009-10-08 |
2023-08-12 |
Not clear |
John J Strouse, Lori C Jordan, Sophie Lanzkron, James F Casell. The excess burden of stroke in hospitalized adults with sickle cell disease. American journal of hematology. vol 84. issue 9. 2009-10-08. PMID:19623672. |
stroke in scd is associated with several known adult risk factors for ischemic and hemorrhagic stroke. |
2009-10-08 |
2023-08-12 |
Not clear |
John J Strouse, Lori C Jordan, Sophie Lanzkron, James F Casell. The excess burden of stroke in hospitalized adults with sickle cell disease. American journal of hematology. vol 84. issue 9. 2009-10-08. PMID:19623672. |
studies for the primary and secondary prevention of stroke in adults with scd are urgently needed. |
2009-10-08 |
2023-08-12 |
Not clear |
Marianne E McPherson, Alan R Anderson, Ann E Haight, Paula Jessup, Marta-Inés Castillejo, Christopher D Hillyer, Cassandra D Josephso. Transfusion management of sickle cell patients during bone marrow transplantation with matched sibling donor. Transfusion. vol 49. issue 9. 2009-09-23. PMID:19453984. |
sickle cell disease (scd) patients have unique transfusion considerations during bone marrow transplantation (bmt), including prophylaxis against stroke and alloimmunization. |
2009-09-23 |
2023-08-12 |
Not clear |
Michael R Debaun, Joshua J Fiel. Limitations of clinical trials in sickle cell disease: a case study of the Multi-center Study of Hydroxyurea (MSH) trial and the Stroke Prevention (STOP) trial. Hematology. American Society of Hematology. Education Program. 2009-07-14. PMID:18024668. |
in the past two decades, two landmark randomized controlled trials (rct) have been completed among individuals with sickle cell disease (scd), the multi-center study of hydroxyurea (msh) trial and the stroke prevention (stop) trial. |
2009-07-14 |
2023-08-12 |
human |
Valentine Brousse, Lucie Hertz-Pannier, Yann Consigny, Jean-Louis Bresson, Robert Girot, Elsa Mirre, Gérard Lenoir, Mariane de Montalember. Does regular blood transfusion prevent progression of cerebrovascular lesions in children with sickle cell disease? Annals of hematology. vol 88. issue 8. 2009-07-07. PMID:19107481. |
a retrospective study was conducted to assess changes in cerebrovascular lesions, as assessed by magnetic resonance (mr) imaging and angiography in 18 children with sickle cell disease (scd) receiving optimised chronic transfusions for primary stroke prevention (abnormal transcranial doppler flow, nine patients, median follow-up 14.3 months (range, 7.9-48.9)) or secondary stroke prevention (nine patients, median follow-up 59.6 months (range, 11.0-127.9)). |
2009-07-07 |
2023-08-12 |
Not clear |
Valentine Brousse, Lucie Hertz-Pannier, Yann Consigny, Jean-Louis Bresson, Robert Girot, Elsa Mirre, Gérard Lenoir, Mariane de Montalember. Does regular blood transfusion prevent progression of cerebrovascular lesions in children with sickle cell disease? Annals of hematology. vol 88. issue 8. 2009-07-07. PMID:19107481. |
optimised transfusion therapy does not prevent progression of cerebral vasculopathy in scd children with a history of stroke. |
2009-07-07 |
2023-08-12 |
Not clear |
Françoise Bernaudin, Suzanne Verlha. [Stroke prevention in sickle-cell disease: results, hurdles and future perspectives]. Bulletin de l'Academie nationale de medecine. vol 192. issue 7. 2009-06-26. PMID:19445364. |
sickle cell disease (scd) is the most frequent cause of stroke during infancy, and stroke is the most serious complication of scd in children. |
2009-06-26 |
2023-08-12 |
Not clear |
Françoise Bernaudin, Suzanne Verlha. [Stroke prevention in sickle-cell disease: results, hurdles and future perspectives]. Bulletin de l'Academie nationale de medecine. vol 192. issue 7. 2009-06-26. PMID:19445364. |
sludge-induced distal vasculopathy explains 25% of strokes in scd, while proximal vasculopathy is responsible for 75% of cases. |
2009-06-26 |
2023-08-12 |
Not clear |
Françoise Bernaudin, Suzanne Verlha. [Stroke prevention in sickle-cell disease: results, hurdles and future perspectives]. Bulletin de l'Academie nationale de medecine. vol 192. issue 7. 2009-06-26. PMID:19445364. |
this approach has been adopted in our institution, based on a cohort of scd newborns screened at birth: the risk of stroke was reduced from the expected 11% to less than 2% at 18 years. |
2009-06-26 |
2023-08-12 |
Not clear |