Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Abdulaziz Mohammad Al-Sharydah, Hussain Khalid Al-Arfaj, Sari Saleh Al-Suhibani, Fahad Safran Al-Safran, Abdulrahman Hamad Al-Abdulwahhab, Saeed Ahmad Al-Jubran, Abdulhadi Ahmad AlSafla. Pediatric Stroke from Bench to Bedside: A Single-Center Experience in Saudi Arabia. Vascular health and risk management. vol 18. 2022-07-21. PMID:35860750. |
this study aimed to determine the genetic background, causative factors, and diagnostic and outcome measures of pediatric stroke in an area endemic to sickle cell disease (scd). |
2022-07-21 |
2023-08-14 |
Not clear |
Lina Okar, Hadeel Ali Alzoubi, Safa Shukur Mahmud, Ahmed Elyas, Mohamed A Yassi. Dilemma in approach to stroke in sickle cell disease patient: A case report. Medicine. vol 101. issue 28. 2022-07-15. PMID:35839057. |
cerebrovascular accidents in sickle cell disease (scd) patients carry a high socioeconomic impact and represent the most important cause of morbidity, neurological deficits, and impaired quality of life in scd young population.patent foramen ovale (pfo) is prevalent in 25% of the general population and it is associated with ischemic stroke in the young population via paradoxical embolism, yet there are no specific guidelines to address how to manage scd patients with pfo who suffer a stroke. |
2022-07-15 |
2023-08-14 |
Not clear |
Bhakti Gajjar, Sanjay Sharma, Erum Khan, Pranita Sharma, Pawan Jain, Vikas Goel, Arvind Neral, Jyotish Patel, Mamta Parmar, Kanika Sharma, Vijay K Sharma, Arvind K Sharm. Cerebral hemodynamics in children with sickle cell disease in India: An observational cohort study. Medicine. vol 101. issue 27. 2022-07-08. PMID:35801747. |
stroke and cerebral hemodynamic alterations are common among indian children with scd. |
2022-07-08 |
2023-08-14 |
Not clear |
Brian R Peine, Michael U Callaghan, Joseph H Callaghan, Alexander K Glaro. Prophylactic Hydroxyurea Treatment Is Associated with Improved Cerebral Hemodynamics as a Surrogate Marker of Stroke Risk in Sickle Cell Disease: A Retrospective Comparative Analysis. Journal of clinical medicine. vol 11. issue 12. 2022-06-24. PMID:35743561. |
sickle cell disease (scd) increases the incidence of childhood stroke eighty-fold. |
2022-06-24 |
2023-08-14 |
Not clear |
Brian R Peine, Michael U Callaghan, Joseph H Callaghan, Alexander K Glaro. Prophylactic Hydroxyurea Treatment Is Associated with Improved Cerebral Hemodynamics as a Surrogate Marker of Stroke Risk in Sickle Cell Disease: A Retrospective Comparative Analysis. Journal of clinical medicine. vol 11. issue 12. 2022-06-24. PMID:35743561. |
a high mca blood velocity indicates increased stroke risk due to cerebral vasculopathy, and first-line treatment to prevent primary or recurrent strokes in high-risk children with scd has classically been chronic blood transfusions. |
2022-06-24 |
2023-08-14 |
Not clear |
Brian R Peine, Michael U Callaghan, Joseph H Callaghan, Alexander K Glaro. Prophylactic Hydroxyurea Treatment Is Associated with Improved Cerebral Hemodynamics as a Surrogate Marker of Stroke Risk in Sickle Cell Disease: A Retrospective Comparative Analysis. Journal of clinical medicine. vol 11. issue 12. 2022-06-24. PMID:35743561. |
our retrospective study aimed to document the long-term effects of hu treatment compared with no hu treatment in children with scd, using tcd measurements as our primary outcome and a surrogate marker of stroke risk. |
2022-06-24 |
2023-08-14 |
Not clear |
Nicolas Girerd, John Cleland, Stefan D Anker, William Byra, Carolyn S P Lam, David Lapolice, Mandeep R Mehra, Dirk J van Veldhuisen, Emmanuel Bresso, Zohra Lamiral, Barry Greenberg, Faiez Zanna. Inflammation and remodeling pathways and risk of cardiovascular events in patients with ischemic heart failure and reduced ejection fraction. Scientific reports. vol 12. issue 1. 2022-05-20. PMID:35595781. |
patients with the following first clinical events: hf hospitalization, scd and the composite of mi or stroke were matched with corresponding controls for age, sex and study drug. |
2022-05-20 |
2023-08-13 |
Not clear |
Ivana Markovic, Zoran Milenkovic, Bosanka Jocic-Jakubi, Amna Al Futaisi, Kakaria Anupam Kakaria, Yasser Wall. Stroke in sickle cell disease in association with bilateral absence of the internal carotid arteries. Case report. BMC neurology. vol 22. issue 1. 2022-05-17. PMID:35581570. |
sickle cell disease (scd) is a serious disorder and carries a high risk of stroke. |
2022-05-17 |
2023-08-13 |
Not clear |
Sylvia Thurn, Katharina Kleinschmidt, Irena Kovacic, Christina Wendl, Ralf A Linker, Selim Corbacioglu, Felix Schlachetzk. Transcranial Doppler sonography and the effect of haematopoietic stem cell transplantation in sickle cell disease. Neurological research and practice. vol 4. issue 1. 2022-04-04. PMID:35369878. |
sickle cell disease (scd) is one of the most prevalent monogenetic diseases worldwide and one of the most serious complications is stroke. |
2022-04-04 |
2023-08-13 |
Not clear |
Carolyn E Beck, Evelyne D Trottier, Melanie Kirby-Allen, Yves Pastor. Acute complications in children with sickle cell disease: Prevention and management. Paediatrics & child health. vol 27. issue 1. 2022-03-11. PMID:35273671. |
case vignettes demonstrate principles of care for common acute complications of scd: vaso-occlusive episodes (voe), acute chest syndrome (acs), fever, splenic sequestration, aplastic crises, and stroke. |
2022-03-11 |
2023-08-13 |
Not clear |
Bartholomew Chukwu, Lyra Menezes, Thiago Fukuda, Jamary Filho, Marilda Goncalve. Timed Average Mean Maximum Velocity (TAMMV) of Cerebral Blood Flow of Children and Adolescents with Sickle cell Disease: correlation with clinical and hematological profiles in country. Malawi medical journal : the journal of Medical Association of Malawi. vol 33. issue 3. 2022-03-02. PMID:35233274. |
detection of abnormal tammv with transcranial doppler is fundamental in primary stroke prevention in children with sickle cell disease (scd). |
2022-03-02 |
2023-08-13 |
Not clear |
Samaa Y Takroni, Abdulrahman M Nasiri, Elguneid Ahmed, Reem A Alkharra. Spontaneous epidural hematoma: A case report of rare crisis of sickle cell disease. Journal of family medicine and primary care. vol 10. issue 11. 2022-02-09. PMID:35136803. |
the clinical consequences of scd include pain crisis, acute chest syndrome, and strokes. |
2022-02-09 |
2023-08-13 |
Not clear |
b' Olivia Edwards, Alicia Burris, Josh Lua, Diana J Wilkie, Miriam O Ezenwa, Sylvain Dor\\xc3\\xa. Influence of Haptoglobin Polymorphism on Stroke in Sickle Cell Disease Patients. Genes. vol 13. issue 1. 2022-01-21. PMID:35052484.' |
this review outlines the current clinical research investigating how the haptoglobin (hp) genetic polymorphism and stroke occurrence are implicated in sickle cell disease (scd) pathophysiology. |
2022-01-21 |
2023-08-13 |
Not clear |
b' Olivia Edwards, Alicia Burris, Josh Lua, Diana J Wilkie, Miriam O Ezenwa, Sylvain Dor\\xc3\\xa. Influence of Haptoglobin Polymorphism on Stroke in Sickle Cell Disease Patients. Genes. vol 13. issue 1. 2022-01-21. PMID:35052484.' |
the role of hp in patients with scd is critical in combating blood toxicity, inflammation, oxidative stress, and even stroke. |
2022-01-21 |
2023-08-13 |
Not clear |
b' Olivia Edwards, Alicia Burris, Josh Lua, Diana J Wilkie, Miriam O Ezenwa, Sylvain Dor\\xc3\\xa. Influence of Haptoglobin Polymorphism on Stroke in Sickle Cell Disease Patients. Genes. vol 13. issue 1. 2022-01-21. PMID:35052484.' |
this review is the first to evaluate the role of the hp polymorphism in the incidence of stroke in patients with scd. |
2022-01-21 |
2023-08-13 |
Not clear |
Eboni I Lance, Lisa M Faulcon, Zongming Fu, Jun Yang, Donna Whyte-Stewart, John J Strouse, Emily Barron-Casella, Kimberly Jones, Jennifer E Van Eyk, James F Casella, Allen D Everet. Proteomic discovery in sickle cell disease: Elevated neurogranin levels in children with sickle cell disease. Proteomics. Clinical applications. vol 15. issue 5. 2021-11-17. PMID:33915030. |
sickle cell disease (scd) is an inherited hemoglobinopathy that causes stroke and silent cerebral infarct (sci). |
2021-11-17 |
2023-08-13 |
Not clear |
Constantina Aggeli, Kali Polytarchou, Yannis Dimitroglou, Dimitrios Patsourakos, Sophia Delicou, Sophia Vassilopoulou, Eleftherios Tsiamis, Kostas Tsioufi. Stroke and presence of patent foramen ovale in sickle cell disease. Journal of thrombosis and thrombolysis. vol 52. issue 3. 2021-11-11. PMID:33638018. |
children with scd have a 300-fold higher risk of acute stroke and by the age of 45 about 25% of patients have suffered an overt stoke. |
2021-11-11 |
2023-08-13 |
Not clear |
Constantina Aggeli, Kali Polytarchou, Yannis Dimitroglou, Dimitrios Patsourakos, Sophia Delicou, Sophia Vassilopoulou, Eleftherios Tsiamis, Kostas Tsioufi. Stroke and presence of patent foramen ovale in sickle cell disease. Journal of thrombosis and thrombolysis. vol 52. issue 3. 2021-11-11. PMID:33638018. |
management and prevention of stroke in patients with scd is not well defined. |
2021-11-11 |
2023-08-13 |
Not clear |
Constantina Aggeli, Kali Polytarchou, Yannis Dimitroglou, Dimitrios Patsourakos, Sophia Delicou, Sophia Vassilopoulou, Eleftherios Tsiamis, Kostas Tsioufi. Stroke and presence of patent foramen ovale in sickle cell disease. Journal of thrombosis and thrombolysis. vol 52. issue 3. 2021-11-11. PMID:33638018. |
moreover, during covid-19 pandemic and taking into account the increased rates of thrombotic events and the difficulties in blood transfusion, management of scd patients is even more challenging and difficult, since data are scarce regarding stroke occurrence and management in this specific population in the covid-19 era. |
2021-11-11 |
2023-08-13 |
Not clear |
Constantina Aggeli, Kali Polytarchou, Yannis Dimitroglou, Dimitrios Patsourakos, Sophia Delicou, Sophia Vassilopoulou, Eleftherios Tsiamis, Kostas Tsioufi. Stroke and presence of patent foramen ovale in sickle cell disease. Journal of thrombosis and thrombolysis. vol 52. issue 3. 2021-11-11. PMID:33638018. |
this review focuses on pathophysiology of stroke in patients with scd and possible treatment strategies in the presence of pfo. |
2021-11-11 |
2023-08-13 |
Not clear |