| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paresh Manna, Krishnan K Narang, Sunil K Mann. 1,2,4-Thiadiazolidine derivative inhibits nuclear transcription factor-kappaB and its dependent genes activation but induces apoptosis. International journal of cancer. vol 113. issue 4. 2005-01-19. PMID:15389516. |
unlike other substitutary derivatives, p(3)-25 was a potent inducer of apoptosis as it induced cell death, caspase-dependent parp cleavage, roi generation and lipid peroxidation. |
2005-01-19 |
2023-08-12 |
human |
| Futoshi Hirai, Shigeatsu Motoori, Shizuko Kakinuma, Kazuo Tomita, Hiroko P Indo, Hirotoshi Kato, Taketo Yamaguchi, Hsiu-Chuan Yen, Daret K St Clair, Tetsuo Nagano, Toshihiko Ozawa, Hiromitsu Saisho, Hideyuki J Majim. Mitochondrial signal lacking manganese superoxide dismutase failed to prevent cell death by reoxygenation following hypoxia in a human pancreatic cancer cell line, KP4. Antioxidants & redox signaling. vol 6. issue 3. 2004-12-10. PMID:15130279. |
normal human mnsod and mnsod without a mitochondrial targeting signal were transfected to kp4 cells, and reactive oxygen species, nitric oxide, lipid peroxidation, and apoptosis were examined as a function of time in air following 1 day of hypoxia as a h/r model. |
2004-12-10 |
2023-08-12 |
human |
| Ai-Guo Wang, Tao Xia, Qi-Long Chu, Ming Zhang, Fang Liu, Xue-Min Chen, Ke-Di Yan. Effects of fluoride on lipid peroxidation, DNA damage and apoptosis in human embryo hepatocytes. Biomedical and environmental sciences : BES. vol 17. issue 2. 2004-12-10. PMID:15386948. |
effects of fluoride on lipid peroxidation, dna damage and apoptosis in human embryo hepatocytes. |
2004-12-10 |
2023-08-12 |
human |
| Ai-Guo Wang, Tao Xia, Qi-Long Chu, Ming Zhang, Fang Liu, Xue-Min Chen, Ke-Di Yan. Effects of fluoride on lipid peroxidation, DNA damage and apoptosis in human embryo hepatocytes. Biomedical and environmental sciences : BES. vol 17. issue 2. 2004-12-10. PMID:15386948. |
to investigate the effects of fluoride on lipid peroxidation, dna damage and apoptosis in human embryo hepatocyte l-02 cells. |
2004-12-10 |
2023-08-12 |
human |
| H A Leaver, J R Williams, C Smith, I R Whittl. Intracellular oxidation by human glioma cell populations: effect of arachidonic acid. Prostaglandins, leukotrienes, and essential fatty acids. vol 70. issue 5. 2004-11-30. PMID:15062847. |
arachidonic acid (aa) and gamma linolenic acid have been shown to limit glioma cell growth, stimulate apoptosis and lipid peroxidation. |
2004-11-30 |
2023-08-12 |
human |
| Rukhsana Sultana, Shelley Newman, Hafiz Mohmmad-Abdul, Jeffery N Keller, D Allan Butterfiel. Protective effect of the xanthate, D609, on Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress in primary neuronal cells. Free radical research. vol 38. issue 5. 2004-11-23. PMID:15293552. |
pretreatment of primary hippocampal cultures with d609 significantly attenuated abeta(1-42)-induced cytotoxicity, intracellular ros accumulation, protein oxidation, lipid peroxidation and apoptosis. |
2004-11-23 |
2023-08-12 |
Not clear |
| Maristella C Anazetti, Patricia S Melo, Nelson Durán, Marcela Hau. Dehydrocrotonin and its derivative, dimethylamide-crotonin induce apoptosis with lipid peroxidation and activation of caspases-2, -6 and -9 in human leukemic cells HL60. Toxicology. vol 203. issue 1-3. 2004-11-19. PMID:15363588. |
dehydrocrotonin and its derivative, dimethylamide-crotonin induce apoptosis with lipid peroxidation and activation of caspases-2, -6 and -9 in human leukemic cells hl60. |
2004-11-19 |
2023-08-12 |
human |
| Maristella C Anazetti, Patricia S Melo, Nelson Durán, Marcela Hau. Dehydrocrotonin and its derivative, dimethylamide-crotonin induce apoptosis with lipid peroxidation and activation of caspases-2, -6 and -9 in human leukemic cells HL60. Toxicology. vol 203. issue 1-3. 2004-11-19. PMID:15363588. |
these results indicate that dcr and dhc produced apoptosis partly by oxidative stress-induced lipid peroxidation, which triggered the caspase cascade, that lead to apoptotic cell death in hl60 cells. |
2004-11-19 |
2023-08-12 |
human |
| Tatiana Armeni, Elisabetta Damiani, Maurizio Battino, Lucedio Greci, Giovanni Principat. Lack of in vitro protection by a common sunscreen ingredient on UVA-induced cytotoxicity in keratinocytes. Toxicology. vol 203. issue 1-3. 2004-11-19. PMID:15363592. |
the results obtained show that uva exposure induces significant cell mortality, decrease in protein concentration, release of ldh, increase in apoptosis, oxidative stress and lipid peroxidation with a concomitant reduction in the response of the antioxidant cellular defense system. |
2004-11-19 |
2023-08-12 |
human |
| Melanie Baumgartner, Sanda Sturlan, Erich Roth, Barbara Wessner, Thomas Bachleitner-Hofman. Enhancement of arsenic trioxide-mediated apoptosis using docosahexaenoic acid in arsenic trioxide-resistant solid tumor cells. International journal of cancer. vol 112. issue 4. 2004-11-16. PMID:15382055. |
the cytotoxic effect of as2o3 and dha was associated with the induction of apoptosis and a concomitant increase of intracellular lipid peroxidation products. |
2004-11-16 |
2023-08-12 |
human |
| Jordi Roca, Maria A Gil, Marta Hernandez, Inma Parrilla, Juan M Vazquez, Emilio A Martine. Survival and fertility of boar spermatozoa after freeze-thawing in extender supplemented with butylated hydroxytoluene. Journal of andrology. vol 25. issue 3. 2004-11-09. PMID:15064318. |
in experiment 2, sperm survivability was evaluated when bht was added to a postthaw freezing extender by measuring the degree of sperm lipid peroxidation (using mda production) and by measuring parameter such as motility, plasma membrane and acrosome integrity, and cell apoptosis. |
2004-11-09 |
2023-08-12 |
Not clear |
| James D West, Chuan Ji, Stephen T Duncan, Venkataraman Amarnath, Claus Schneider, Carmelo J Rizzo, Alan R Brash, Lawrence J Marnet. Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation. Chemical research in toxicology. vol 17. issue 4. 2004-11-09. PMID:15089087. |
induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation. |
2004-11-09 |
2023-08-12 |
human |
| Margie Castillo-Meléndez, Jo Ann Chow, David W Walke. Lipid peroxidation, caspase-3 immunoreactivity, and pyknosis in late-gestation fetal sheep brain after umbilical cord occlusion. Pediatric research. vol 55. issue 5. 2004-11-08. PMID:14764919. |
we have determined the effects of two 10-min uco on the distribution of the lipid peroxidation marker 4-hydroxynonenal (4-hne) and the activated form of the apoptosis marker caspase-3 in the brains of late-gestation fetal sheep. |
2004-11-08 |
2023-08-12 |
Not clear |
| Margie Castillo-Meléndez, Jo Ann Chow, David W Walke. Lipid peroxidation, caspase-3 immunoreactivity, and pyknosis in late-gestation fetal sheep brain after umbilical cord occlusion. Pediatric research. vol 55. issue 5. 2004-11-08. PMID:14764919. |
these data indicate that brief asphyxia induces widespread lipid peroxidation involving all cell types of the fetal brain and apoptosis in both neurons and glia. |
2004-11-08 |
2023-08-12 |
Not clear |
| N Philips, D Burchill, D O'Donoghue, T Keller, S Gonzale. Identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites. Skin pharmacology and physiology. vol 17. issue 3. 2004-10-19. PMID:15087594. |
identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites. |
2004-10-19 |
2023-08-12 |
Not clear |
| N Philips, D Burchill, D O'Donoghue, T Keller, S Gonzale. Identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites. Skin pharmacology and physiology. vol 17. issue 3. 2004-10-19. PMID:15087594. |
these metabolites were not toxic to the cells with regard to cell viability, apoptosis and lipid peroxidation, unlike the phenolic benzene metabolites (hydroquinone, t-butyl hydroquinone and phenol) or hydrogen peroxide. |
2004-10-19 |
2023-08-12 |
Not clear |
| Tsuyoshi Tsuzuki, Yoshiko Tokuyama, Miki Igarashi, Teruo Miyazaw. Tumor growth suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation. Carcinogenesis. vol 25. issue 8. 2004-09-10. PMID:14963014. |
dna fragmentation was enhanced and lipid peroxidation was increased in tumor tissues of the alpha-esa-fed mice, which suggested that alpha-esa induced apoptosis via lipid peroxidation. |
2004-09-10 |
2023-08-12 |
mouse |
| Tsuyoshi Tsuzuki, Yoshiko Tokuyama, Miki Igarashi, Teruo Miyazaw. Tumor growth suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation. Carcinogenesis. vol 25. issue 8. 2004-09-10. PMID:14963014. |
addition of alpha-tocopherol, an antioxidant, suppressed oxidative stress and apoptosis, suggesting that these effects were associated with lipid peroxidation. |
2004-09-10 |
2023-08-12 |
mouse |
| Ji-Young Lee, Jae-Won Kim, Su-Dong Cho, Yong-Hoon Kim, Kang-Ju Choi, Woo-Hong Joo, Yong-Kweon Cho, Ja-Young Moo. Protective effect of ginseng extract against apoptotic cell death induced by 2,2',5,5'-tetrachlorobiphenyl in neuronal SK-N-MC cells. Life sciences. vol 75. issue 13. 2004-08-25. PMID:15261766. |
the addition of 500 microg/ml of ginseng extract to a culture medium significantly protected neuronal cell from the apoptosis mediated by pcb 52 and remarkably attenuated lipid peroxidation, the generation of reactive oxygen species, and dna fragmentation, and markedly reduced the pcb 52 induced proteolytic cleavage of beta-catenin and parp. |
2004-08-25 |
2023-08-12 |
human |
| Jun Xie, Qing Gu. AATF protects neural cells against oxidative damage induced by amyloid beta-peptide. Neurobiology of disease. vol 16. issue 1. 2004-08-18. PMID:15207272. |
overexpression of aatf suppressed superoxide production, inhibited peroxynitrite formation and membrane lipid peroxidation, and protected against abeta-induced apoptosis in pc12 cells. |
2004-08-18 |
2023-08-12 |
Not clear |