Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Tzeon-Jye Chiou, Sin-Tak Chu, Woan-Fang Tzen. Protection of cells from menadione-induced apoptosis by inhibition of lipid peroxidation. Toxicology. vol 191. issue 2-3. 2003-10-28. PMID:12965111. |
protection of cells from menadione-induced apoptosis by inhibition of lipid peroxidation. |
2003-10-28 |
2023-08-12 |
mouse |
Tzeon-Jye Chiou, Sin-Tak Chu, Woan-Fang Tzen. Protection of cells from menadione-induced apoptosis by inhibition of lipid peroxidation. Toxicology. vol 191. issue 2-3. 2003-10-28. PMID:12965111. |
pre-treatment of cells with cysteine suppressed the menadione-induced apoptosis and prevented changes in reactive oxygen species levels, glutathione levels and lipid peroxidation. |
2003-10-28 |
2023-08-12 |
mouse |
Tzeon-Jye Chiou, Sin-Tak Chu, Woan-Fang Tzen. Protection of cells from menadione-induced apoptosis by inhibition of lipid peroxidation. Toxicology. vol 191. issue 2-3. 2003-10-28. PMID:12965111. |
pre-treatment of cells with deferoxamine mesylate, an iron chelator, also reduced both menadione-induced apoptosis and lipid peroxidation. |
2003-10-28 |
2023-08-12 |
mouse |
Tzeon-Jye Chiou, Sin-Tak Chu, Woan-Fang Tzen. Protection of cells from menadione-induced apoptosis by inhibition of lipid peroxidation. Toxicology. vol 191. issue 2-3. 2003-10-28. PMID:12965111. |
thus, the inhibition of lipid peroxidation by deferoxamine mesylate prevented apoptosis even though cellular glutathione remained depleted. |
2003-10-28 |
2023-08-12 |
mouse |
Tzeon-Jye Chiou, Sin-Tak Chu, Woan-Fang Tzen. Protection of cells from menadione-induced apoptosis by inhibition of lipid peroxidation. Toxicology. vol 191. issue 2-3. 2003-10-28. PMID:12965111. |
our data suggest that menadione-induced apoptosis is directly linked to iron-dependent lipid peroxidation. |
2003-10-28 |
2023-08-12 |
mouse |
Laurens Kruidenier, Ineke Kuiper, Cornelis B H W Lamers, Hein W Verspage. Intestinal oxidative damage in inflammatory bowel disease: semi-quantification, localization, and association with mucosal antioxidants. The Journal of pathology. vol 201. issue 1. 2003-10-24. PMID:12950014. |
the extent of apoptosis, peroxynitrite-mediated protein nitration (3-nt), and lipid peroxidation were assessed in relation to the expression of nitric oxide synthase (nos) and the superoxide-producing enzyme xanthine oxidase (xo). |
2003-10-24 |
2023-08-12 |
Not clear |
Hsiu-Chuan Yen, Chung-Yi Nien, Hideyuki J Majima, Chia-Pei Lee, Sz-Yun Chen, Jeng-Shu Wei, Lai-Chu Se. Increase of lipid peroxidation by cisplatin in WI38 cells but not in SV40-transformed WI38 cells. Journal of biochemical and molecular toxicology. vol 17. issue 1. 2003-10-23. PMID:12616645. |
in this study, by using normal human lung fibroblast (w138) cells and sv40-transformed wi38 (va13) cells as a model, we compared the effect of cpt on cytotoxicity, apoptosis, lipid peroxidation, and mitochondrial gene expression, which could be regulated by oxidative stress, between normal and tumor cells. |
2003-10-23 |
2023-08-12 |
human |
Jingyuan Chen, Yaoming Chen, Wenjing Luo, Xiuhong Li. [Toxicity effects of manganese on PC12 cells]. Wei sheng yan jiu = Journal of hygiene research. vol 31. issue 4. 2003-08-21. PMID:12600022. |
mtt test, trypan blue exclusion test, malondiadehyde(mda) colorimetry and dna gel electrophoresis were performed to exam proliferation, lipid peroxidation, and apoptosis of pc12 cells. |
2003-08-21 |
2023-08-12 |
Not clear |
Jingyuan Chen, Yaoming Chen, Wenjing Luo, Xiuhong Li. [Toxicity effects of manganese on PC12 cells]. Wei sheng yan jiu = Journal of hygiene research. vol 31. issue 4. 2003-08-21. PMID:12600022. |
it is concluded that manganese can inhibit proliferation of pc12 cells, the mechanism includes the interference of dna metabolism, inhibitory of lipid peroxidation, and cell apoptosis. |
2003-08-21 |
2023-08-12 |
Not clear |
G Benitez-King, I Túnez, A Bellon, G G Ortíz, F Antón-Ta. Melatonin prevents cytoskeletal alterations and oxidative stress induced by okadaic acid in N1E-115 cells. Experimental neurology. vol 182. issue 1. 2003-08-06. PMID:12821385. |
also, increased lipid peroxidation and augmented apoptosis in n1e-115 cells incubated with 50 nm oa were prevented by melatonin. |
2003-08-06 |
2023-08-12 |
Not clear |
A V Alessenko, E I Galperin, L B Dudnik, V G Korobko, E S Mochalova, L V Platonova, L N Shingarova, N I Shono, M A Shupi. Role of tumor necrosis factor alpha and sphingomyelin cycle activation in the induction of apoptosis by ischemia/reperfusion of the liver. Biochemistry. Biokhimiia. vol 67. issue 12. 2003-08-04. PMID:12600263. |
in the present study involvement of the tnf-alpha, sphingomyelin cycle, and lipid peroxidation in the initiation of apoptosis induced in liver cells by ischemia and reperfusion was investigated. |
2003-08-04 |
2023-08-12 |
rat |
María Teresa Ronco, Maria Luján deAlvarez, Juan Monti, María Cristina Carrillo, Gerardo Pisani, María Cristina Lugano, Cristina E Carnoval. Modulation of balance between apoptosis and proliferation by lipid peroxidation (LPO) during rat liver regeneration. Molecular medicine (Cambridge, Mass.). vol 8. issue 12. 2003-08-01. PMID:12606815. |
modulation of balance between apoptosis and proliferation by lipid peroxidation (lpo) during rat liver regeneration. |
2003-08-01 |
2023-08-12 |
rat |
María Teresa Ronco, Maria Luján deAlvarez, Juan Monti, María Cristina Carrillo, Gerardo Pisani, María Cristina Lugano, Cristina E Carnoval. Modulation of balance between apoptosis and proliferation by lipid peroxidation (LPO) during rat liver regeneration. Molecular medicine (Cambridge, Mass.). vol 8. issue 12. 2003-08-01. PMID:12606815. |
this work aims to investigate the role of lipid peroxidation (lpo) at early stages of liver regeneration and to evaluate the balance between apoptosis and cell proliferation during this process. |
2003-08-01 |
2023-08-12 |
rat |
Yashin Sreenivasan, Abira Sarkar, Sunil K Mann. Mechanism of cytosine arabinoside-mediated apoptosis: role of Rel A (p65) dephosphorylation. Oncogene. vol 22. issue 28. 2003-08-01. PMID:12853972. |
arac, but not tnf or ceramide was able to induce apoptosis in these cells as detected by assays for lipid peroxidation, reactive oxygen intermediates generation, caspase activation, cytotoxicity, bcl-2 degradation, and dna fragmentation. |
2003-08-01 |
2023-08-12 |
Not clear |
Ali Ozdulger, Ismail Cinel, Oguz Koksel, Leyla Cinel, Dincer Avlan, Ali Unlu, Hulya Okcu, Murat Dikmengil, Ugur Ora. The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model. Shock (Augusta, Ga.). vol 19. issue 4. 2003-07-14. PMID:12688549. |
in conclusion, the chronic use of nac inhibited mpo activity and lipid peroxidation, which resulted in reduction of apoptosis in lung in this clp model. |
2003-07-14 |
2023-08-12 |
rat |
C Matthew Peterson, Jane-Guo Shiah, Yongen Sun, Pavla Kopecková, Tamara Minko, Richard C Straight, Jindrich Kopece. HPMA copolymer delivery of chemotherapy and photodynamic therapy in ovarian cancer. Advances in experimental medicine and biology. vol 519. 2003-06-19. PMID:12675211. |
it demonstrates marked advantages over free doxorubicin: control of biodistribution and accumulation via molecular weight restrictions, biodegradability, minimal immunogenicity, subcellular localization, anticancer activity, enhanced permeability and retention, increased apoptosis, lipid peroxidation, dna damage, and reduced nonspecific toxicity. |
2003-06-19 |
2023-08-12 |
Not clear |
G G Ziangirova, O V Antonov. [Local senile ocular amyloidosis in the pathogenesis of open-angle glaucoma and pseudo-exfoliative syndrome]. Vestnik Rossiiskoi akademii meditsinskikh nauk. issue 2. 2003-06-17. PMID:12698889. |
amyloid angiopathy of the iris is a key element of ischemia, which triggers the mechanisms of apoptosis and lipid peroxidation in the pigment epithelium membranes; this process is accompanied by an intensified synthesis and conformation of fibrous structures of tauprotein and beta-amyloid. |
2003-06-17 |
2023-08-12 |
Not clear |
Oxana R Kunduzova, Ghislaine Escourrou, Marie-Helene Seguelas, Philippe Delagrange, France De La Farge, Claudie Cambon, Angelo Parin. Prevention of apoptotic and necrotic cell death, caspase-3 activation, and renal dysfunction by melatonin after ischemia/reperfusion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 8. 2003-06-02. PMID:12670883. |
using an in vivo rat model of i/r, we show a significant increase in kidney malondialdehyde concentrations, reflecting lipid peroxidation, and cell apoptosis measured by tunel staining. |
2003-06-02 |
2023-08-12 |
rat |
Oxana R Kunduzova, Ghislaine Escourrou, Marie-Helene Seguelas, Philippe Delagrange, France De La Farge, Claudie Cambon, Angelo Parin. Prevention of apoptotic and necrotic cell death, caspase-3 activation, and renal dysfunction by melatonin after ischemia/reperfusion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 8. 2003-06-02. PMID:12670883. |
rat pretreatment with melatonin prevented lipid peroxidation, cell apoptosis, and necrosis and blocked caspase-3 activity. |
2003-06-02 |
2023-08-12 |
rat |
T Xiao, S Choudhary, W Zhang, N H Ansari, A Salahudee. Possible involvement of oxidative stress in cisplatin-induced apoptosis in LLC-PK1 cells. Journal of toxicology and environmental health. Part A. vol 66. issue 5. 2003-05-07. PMID:12712633. |
it has been suggested that free radical-catalyzed lipid peroxidation can induce apoptosis or necrosis leading to renal injury. |
2003-05-07 |
2023-08-12 |
Not clear |