| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yinghua Ma, Yunxia Wang, Gulinigaer Anwaier, Nuerbiye Tuerdi, Yangchang Wu, Yinyue Huang, Boyang Qin, Haoyue Ma, Qiao Zhang, Dalei Wu, Kewu Zeng, Rong Q. Antrodia cinnamomea triterpenoids attenuate cardiac hypertrophy via the SNW1/RXR/ALDH2 axis. Redox biology. vol 78. 2024-11-26. PMID:39591904. |
through examining cardiac morphology and expression levels of hypertrophic biomarkers, act significantly reduced myocardial hypertrophy induced by angiotensin ii (ang ii) and transverse aortic constriction (tac)surgery in wild-type mice, but not in aldh2 knockout mice. |
2024-11-26 |
2024-11-29 |
mouse |
| Yinghua Ma, Yunxia Wang, Gulinigaer Anwaier, Nuerbiye Tuerdi, Yangchang Wu, Yinyue Huang, Boyang Qin, Haoyue Ma, Qiao Zhang, Dalei Wu, Kewu Zeng, Rong Q. Antrodia cinnamomea triterpenoids attenuate cardiac hypertrophy via the SNW1/RXR/ALDH2 axis. Redox biology. vol 78. 2024-11-26. PMID:39591904. |
in vitro, act and its monomeric dehydrosulphurenic acid (dsa) inhibited the hypertrophic phenotype of ang ii-stimulated neonatal cardiac myocytes (nrcms) in an aldh2-dependent manner. |
2024-11-26 |
2024-11-29 |
mouse |
| Xiaojun Zhang, Zhen Chen, Ning Zhang, Bo Yu, Wei Li, Mengli Zhang, Xian Wu, Ganzhe Liu, Meizhen Don. LncRNA CCAT2 Knockdown Alleviates Pressure Overload or Ang II-Induced Cardiac Hypertrophy Via Disruption of the Wnt/β-Catenin Signaling. Arquivos brasileiros de cardiologia. vol 121. issue 10. 2024-11-13. PMID:39536197. |
lncrna ccat2 knockdown alleviates pressure overload or ang ii-induced cardiac hypertrophy via disruption of the wnt/β-catenin signaling. |
2024-11-13 |
2024-11-17 |
Not clear |
| Bin Zhou, Hui-Fan Fu, Jiang-Feng Niu, Wei Deng, Fu-Mou Deng, Zhi-Dong Zhou, Wei Zhou, Qinggen Xiong, Chang L. The Ubiquitin Ligase HERC2 promotes Ang II-induced cardiac hypertrophy via destabilization of MeCP2 to enhance Lin28a expression. Journal of cardiovascular pharmacology. 2024-11-05. PMID:39499120. |
the ubiquitin ligase herc2 promotes ang ii-induced cardiac hypertrophy via destabilization of mecp2 to enhance lin28a expression. |
2024-11-05 |
2024-11-08 |
Not clear |
| Bin Zhou, Hui-Fan Fu, Jiang-Feng Niu, Wei Deng, Fu-Mou Deng, Zhi-Dong Zhou, Wei Zhou, Qinggen Xiong, Chang L. The Ubiquitin Ligase HERC2 promotes Ang II-induced cardiac hypertrophy via destabilization of MeCP2 to enhance Lin28a expression. Journal of cardiovascular pharmacology. 2024-11-05. PMID:39499120. |
conversely, cardiac specific overexpression of herc2 aggravated ang ii-induced cardiac hypertrophy in vitro and in vivo. |
2024-11-05 |
2024-11-08 |
Not clear |
| Bin Zhou, Hui-Fan Fu, Jiang-Feng Niu, Wei Deng, Fu-Mou Deng, Zhi-Dong Zhou, Wei Zhou, Qinggen Xiong, Chang L. The Ubiquitin Ligase HERC2 promotes Ang II-induced cardiac hypertrophy via destabilization of MeCP2 to enhance Lin28a expression. Journal of cardiovascular pharmacology. 2024-11-05. PMID:39499120. |
in this study, we observed that the expression and activity of herc2 was significantly upregulated in hypertrophic hearts and angiotensin ii (ang ii)-stimulated primary cardiomyocytes. |
2024-11-05 |
2024-11-08 |
Not clear |
| Bin Zhou, Hui-Fan Fu, Jiang-Feng Niu, Wei Deng, Fu-Mou Deng, Zhi-Dong Zhou, Wei Zhou, Qinggen Xiong, Chang L. The Ubiquitin Ligase HERC2 promotes Ang II-induced cardiac hypertrophy via destabilization of MeCP2 to enhance Lin28a expression. Journal of cardiovascular pharmacology. 2024-11-05. PMID:39499120. |
knockdown of herc2 in cardiomyocytes significantly alleviated the myocardial hypertrophy induced by ang ii. |
2024-11-05 |
2024-11-08 |
Not clear |
| Bin Zhou, Hui-Fan Fu, Jiang-Feng Niu, Wei Deng, Fu-Mou Deng, Zhi-Dong Zhou, Wei Zhou, Qinggen Xiong, Chang L. The Ubiquitin Ligase HERC2 promotes Ang II-induced cardiac hypertrophy via destabilization of MeCP2 to enhance Lin28a expression. Journal of cardiovascular pharmacology. 2024-11-05. PMID:39499120. |
knocking down lin28a attenuated ang ii-induced myocardial hypertrophy and abolished the increase in myocardial hypertrophy by overexpression of herc2. |
2024-11-05 |
2024-11-08 |
Not clear |
| Slava Malatiali, Mabayoje Oriow. Losartan is more effective than angiotensin (1-7) in preventing thyroxine-induced renal injury in the rat. Thyroid research. vol 17. issue 1. 2024-11-04. PMID:39491028. |
studies have shown that renal hypertrophy seen in experimental hyperthyroidism induced by thyroxine (t4) is due to angiotensin (ang) ii. |
2024-11-04 |
2024-11-06 |
rat |
| Mei-Ping Zhu, Bing-Yi Zhang, Ting Lian, Yuan-Jia Tan, Lin-Lin Chang, Pan Xu, Jin-Yi Zhang, Yan-Huan Du, Zhen-Yu Xiong, Qiong Du, Shi-Zhong Zhan. Involvement of mitochondrial TRPV3 in cardiac hypertrophy induced by pressure overload in rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 76. issue 5. 2024-10-29. PMID:39468807. |
rat h9c2 myocardial cells were treated with angiotensin ii (ang ii) to establish a hypertrophic myocardial cell model, and trpv3 expression was knocked down using trpv3 small interfering rna (sirna). |
2024-10-29 |
2024-10-31 |
rat |
| Yu Jiang, Wenyao Cai, Guangtao Lei, Guorong Cai, Qinghua Wu, Peng L. Deubiquitinase USP47 ameliorates cardiac hypertrophy through reducing protein O-GlcNAcylation. Journal of cardiovascular pharmacology. 2024-10-22. PMID:39436323. |
here, we observed that the expression level of deubiquitinase usp47 was increased in hypertrophic hearts and angiotensin ii (ang ii)-stimulated neonatal rat cardiomyocytes (nrcms). |
2024-10-22 |
2024-10-24 |
rat |
| Yu Jiang, Wenyao Cai, Guangtao Lei, Guorong Cai, Qinghua Wu, Peng L. Deubiquitinase USP47 ameliorates cardiac hypertrophy through reducing protein O-GlcNAcylation. Journal of cardiovascular pharmacology. 2024-10-22. PMID:39436323. |
adenovirus-mediated gain- and loss-of-function approaches indicated that usp47 overexpression significantly attenuated ang ii-induced cardiac hypertrophy in vitro and in vivo, whereas endogenous usp47 deficiency promoted the pro-hypertrophic effect of ang ii. |
2024-10-22 |
2024-10-24 |
rat |
| Qiying Yao, Xinrui Hu, Tiantian Bian, Qing Zhang, Zhao Xue, Yuesheng Lv, Shupeng Ren, Yue Chen, Dongmei Zhang, Liang Che. Role of KLF4 and SIAT7A interaction accelerates myocardial hypertrophy induced by Ang II. Journal of cellular and molecular medicine. vol 28. issue 20. 2024-10-21. PMID:39431583. |
role of klf4 and siat7a interaction accelerates myocardial hypertrophy induced by ang ii. |
2024-10-21 |
2024-10-23 |
Not clear |
| Qiying Yao, Xinrui Hu, Tiantian Bian, Qing Zhang, Zhao Xue, Yuesheng Lv, Shupeng Ren, Yue Chen, Dongmei Zhang, Liang Che. Role of KLF4 and SIAT7A interaction accelerates myocardial hypertrophy induced by Ang II. Journal of cellular and molecular medicine. vol 28. issue 20. 2024-10-21. PMID:39431583. |
nevertheless, the potential involvement of klf4 in regulating siat7a expression in ang ii-induced hypertrophic cardiomyocytes remains uncertain. |
2024-10-21 |
2024-10-23 |
Not clear |
| Qiying Yao, Xinrui Hu, Tiantian Bian, Qing Zhang, Zhao Xue, Yuesheng Lv, Shupeng Ren, Yue Chen, Dongmei Zhang, Liang Che. Role of KLF4 and SIAT7A interaction accelerates myocardial hypertrophy induced by Ang II. Journal of cellular and molecular medicine. vol 28. issue 20. 2024-10-21. PMID:39431583. |
this study seeks to deepen the underlying mechanisms of the klf4 and siat7a interaction in the progression of ang ii-induced cardiac hypertrophy. |
2024-10-21 |
2024-10-23 |
Not clear |
| Qiying Yao, Xinrui Hu, Tiantian Bian, Qing Zhang, Zhao Xue, Yuesheng Lv, Shupeng Ren, Yue Chen, Dongmei Zhang, Liang Che. Role of KLF4 and SIAT7A interaction accelerates myocardial hypertrophy induced by Ang II. Journal of cellular and molecular medicine. vol 28. issue 20. 2024-10-21. PMID:39431583. |
the results showed a concurrent increase in siat7a and klf4 levels in hypertrophic myocardium of essential hypertension patients and in hypertrophic cardiomyocytes stimulated by ang ii. |
2024-10-21 |
2024-10-23 |
Not clear |
| Qiying Yao, Xinrui Hu, Tiantian Bian, Qing Zhang, Zhao Xue, Yuesheng Lv, Shupeng Ren, Yue Chen, Dongmei Zhang, Liang Che. Role of KLF4 and SIAT7A interaction accelerates myocardial hypertrophy induced by Ang II. Journal of cellular and molecular medicine. vol 28. issue 20. 2024-10-21. PMID:39431583. |
in vitro experiments revealed that reducing klf4 levels led to a decrease in both siat7a synthesis and sialyl-tn antigen expression, consequently inhibiting ang ii-induced cardiomyocyte hypertrophy. |
2024-10-21 |
2024-10-23 |
Not clear |
| Qiying Yao, Xinrui Hu, Tiantian Bian, Qing Zhang, Zhao Xue, Yuesheng Lv, Shupeng Ren, Yue Chen, Dongmei Zhang, Liang Che. Role of KLF4 and SIAT7A interaction accelerates myocardial hypertrophy induced by Ang II. Journal of cellular and molecular medicine. vol 28. issue 20. 2024-10-21. PMID:39431583. |
these findings suggest a positive feedback loop between klf4 and siat7a-sialyl-tn, ultimately promoting ang ii-induced cardiac hypertrophy. |
2024-10-21 |
2024-10-23 |
Not clear |
| Huiye Yang, Xiaotao Wan. A Comparative Discussion on the Selection of Cardiac Hypertrophy Models: TAC Surgery Vs Ang II Infusion [Letter]. Drug design, development and therapy. vol 18. 2024-10-16. PMID:39411153. |
a comparative discussion on the selection of cardiac hypertrophy models: tac surgery vs ang ii infusion [letter]. |
2024-10-16 |
2024-10-18 |
Not clear |
| Tianyu Wu, Yao Lu, Yue Yu, Yan Hua, Gaoyuan Ge, Wei Zhao, Kaiyan Chen, Zhuen Zhong, Fengxiang Zhan. Long noncoding RNA AK144717 exacerbates pathological cardiac hypertrophy through modulating the cellular distribution of HMGB1 and subsequent DNA damage response. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-10-12. PMID:39395058. |
the altered ventricular lncrnas in the mice between sham and transverse aortic constriction (tac) group were identified by microarray analysis, and a novel lncrna ak144717 was found to gradually upregulate during the development of pathological cardiac hypertrophy induced by tac surgery or angiotensin ii (ang ii) stimulation. |
2024-10-12 |
2024-10-15 |
mouse |