| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao Han, Qian-Qiu Zhu, Zhi Li, Jia-Kang He, Yan Sun, Qing-Hua Zhong, Sheng-Xing Tang, Yun-Long Zhan. 4-Hydroxychalcone attenuates AngII-induced cardiac remodeling and dysfunction via regulating PI3K/AKT pathway. Hypertension research : official journal of the Japanese Society of Hypertension. 2024-12-23. PMID:39715792. |
our results indicated that 4-hch significantly ameliorated ang ii-induced hypertension, cardiomyocyte hypertrophy, fibroblast activation, fibrosis, inflammation, superoxide production, and cardiac function. |
2024-12-23 |
2024-12-26 |
mouse |
| Kelly Carter, Eshan Shah, Jessica Waite, Dhruv Rana, Zhi-Qing Zha. Pathophysiology of Angiotensin II-Mediated Hypertension, Cardiac Hypertrophy, and Failure: A Perspective from Macrophages. Cells. vol 13. issue 23. 2024-12-17. PMID:39682749. |
the purpose of this review is to discuss the current understanding in ang ii-induced maladaptive cardiac remodeling and dysfunction, particularly focusing on molecular signaling pathways involved in macrophages-mediated hypertension, cardiac hypertrophy, fibrosis, and failure. |
2024-12-17 |
2024-12-21 |
Not clear |
| Zhiwen Hu, Dijiu Xiao, Liang Wang, Jiaxiang You, Tao Long, Jinping Wang, Yibiao Shang, Dasong Yi, Lu Ding, Xiang Wang, Xiaoping Peng, Junyi Zen. Exosomes derived from cardiac fibroblasts with Ang-II stimulation provoke myocardial hypertrophy via miR-15b-5p/PTEN-L axis. Experimental cell research. 2024-12-14. PMID:39674360. |
this study aimed to examine the impact of exosomes derived from ang ii-stimulated cardiac fibroblasts (cfs) on myocardial hypertrophy. |
2024-12-14 |
2024-12-21 |
rat |
| Zhiwen Hu, Dijiu Xiao, Liang Wang, Jiaxiang You, Tao Long, Jinping Wang, Yibiao Shang, Dasong Yi, Lu Ding, Xiang Wang, Xiaoping Peng, Junyi Zen. Exosomes derived from cardiac fibroblasts with Ang-II stimulation provoke myocardial hypertrophy via miR-15b-5p/PTEN-L axis. Experimental cell research. 2024-12-14. PMID:39674360. |
myocardial hypertrophy models were induced both in vitro and in vivo using ang ii. |
2024-12-14 |
2024-12-21 |
rat |
| Zhiwen Hu, Dijiu Xiao, Liang Wang, Jiaxiang You, Tao Long, Jinping Wang, Yibiao Shang, Dasong Yi, Lu Ding, Xiang Wang, Xiaoping Peng, Junyi Zen. Exosomes derived from cardiac fibroblasts with Ang-II stimulation provoke myocardial hypertrophy via miR-15b-5p/PTEN-L axis. Experimental cell research. 2024-12-14. PMID:39674360. |
ang ii-cfs-exos inhibited cell viability, exacerbated myocardial hypertrophy, and activated mitophagy via mir-15b-5p in the in vitro myocardial hypertrophy model. |
2024-12-14 |
2024-12-21 |
rat |
| Zhiwen Hu, Dijiu Xiao, Liang Wang, Jiaxiang You, Tao Long, Jinping Wang, Yibiao Shang, Dasong Yi, Lu Ding, Xiang Wang, Xiaoping Peng, Junyi Zen. Exosomes derived from cardiac fibroblasts with Ang-II stimulation provoke myocardial hypertrophy via miR-15b-5p/PTEN-L axis. Experimental cell research. 2024-12-14. PMID:39674360. |
furthermore, ang ii-cfs-exos exacerbated myocardial hypertrophy in rats, while knockout of mir-15b-5p in ang ii-cfs-exos mitigated this effect. |
2024-12-14 |
2024-12-21 |
rat |
| Zhiwen Hu, Dijiu Xiao, Liang Wang, Jiaxiang You, Tao Long, Jinping Wang, Yibiao Shang, Dasong Yi, Lu Ding, Xiang Wang, Xiaoping Peng, Junyi Zen. Exosomes derived from cardiac fibroblasts with Ang-II stimulation provoke myocardial hypertrophy via miR-15b-5p/PTEN-L axis. Experimental cell research. 2024-12-14. PMID:39674360. |
to sum up, ang ii-cfs-exos promote myocardial hypertrophy by modulating pink1/parkin signaling -mediated mitophagy through the mir-15b-5p/pten-l axis. |
2024-12-14 |
2024-12-21 |
rat |
| Arianna Scalco, Ethan N Lee, Morgan A Johnson, Michelle L Sorensen, Thomas N Hilton, Riley K Omonaka, Shae Zeimantz, Sue A Aicher, William R Woodward, Beth A Habecke. Hypertension-induced heart failure disrupts cardiac sympathetic innervation. American journal of physiology. Heart and circulatory physiology. vol 327. issue 6. 2024-12-05. PMID:39485300. |
ang ii-treated mice displayed hf phenotype, including reduced cardiac function, hypertrophy, and fibrosis. |
2024-12-05 |
2024-12-07 |
mouse |
| Arianna Scalco, Ethan N Lee, Morgan A Johnson, Michelle L Sorensen, Thomas N Hilton, Riley K Omonaka, Shae Zeimantz, Sue A Aicher, William R Woodward, Beth A Habecke. Hypertension-induced heart failure disrupts cardiac sympathetic innervation. American journal of physiology. Heart and circulatory physiology. vol 327. issue 6. 2024-12-05. PMID:39485300. |
although hf can induce a cholinergic phenotype and neuronal hypertrophy in stellate ganglia, ang ii treatment did not induce a cholinergic phenotype or activation of trophic factors in this study. |
2024-12-05 |
2024-12-07 |
mouse |
| Yinghua Ma, Yunxia Wang, Gulinigaer Anwaier, Nuerbiye Tuerdi, Yangchang Wu, Yinyue Huang, Boyang Qin, Haoyue Ma, Qiao Zhang, Dalei Wu, Kewu Zeng, Rong Q. Antrodia cinnamomea triterpenoids attenuate cardiac hypertrophy via the SNW1/RXR/ALDH2 axis. Redox biology. vol 78. 2024-11-26. PMID:39591904. |
through examining cardiac morphology and expression levels of hypertrophic biomarkers, act significantly reduced myocardial hypertrophy induced by angiotensin ii (ang ii) and transverse aortic constriction (tac)surgery in wild-type mice, but not in aldh2 knockout mice. |
2024-11-26 |
2024-11-29 |
mouse |
| Yinghua Ma, Yunxia Wang, Gulinigaer Anwaier, Nuerbiye Tuerdi, Yangchang Wu, Yinyue Huang, Boyang Qin, Haoyue Ma, Qiao Zhang, Dalei Wu, Kewu Zeng, Rong Q. Antrodia cinnamomea triterpenoids attenuate cardiac hypertrophy via the SNW1/RXR/ALDH2 axis. Redox biology. vol 78. 2024-11-26. PMID:39591904. |
in vitro, act and its monomeric dehydrosulphurenic acid (dsa) inhibited the hypertrophic phenotype of ang ii-stimulated neonatal cardiac myocytes (nrcms) in an aldh2-dependent manner. |
2024-11-26 |
2024-11-29 |
mouse |
| Xiaojun Zhang, Zhen Chen, Ning Zhang, Bo Yu, Wei Li, Mengli Zhang, Xian Wu, Ganzhe Liu, Meizhen Don. LncRNA CCAT2 Knockdown Alleviates Pressure Overload or Ang II-Induced Cardiac Hypertrophy Via Disruption of the Wnt/β-Catenin Signaling. Arquivos brasileiros de cardiologia. vol 121. issue 10. 2024-11-13. PMID:39536197. |
lncrna ccat2 knockdown alleviates pressure overload or ang ii-induced cardiac hypertrophy via disruption of the wnt/β-catenin signaling. |
2024-11-13 |
2024-11-17 |
Not clear |
| Bin Zhou, Hui-Fan Fu, Jiang-Feng Niu, Wei Deng, Fu-Mou Deng, Zhi-Dong Zhou, Wei Zhou, Qinggen Xiong, Chang L. The Ubiquitin Ligase HERC2 promotes Ang II-induced cardiac hypertrophy via destabilization of MeCP2 to enhance Lin28a expression. Journal of cardiovascular pharmacology. 2024-11-05. PMID:39499120. |
the ubiquitin ligase herc2 promotes ang ii-induced cardiac hypertrophy via destabilization of mecp2 to enhance lin28a expression. |
2024-11-05 |
2024-11-08 |
Not clear |
| Bin Zhou, Hui-Fan Fu, Jiang-Feng Niu, Wei Deng, Fu-Mou Deng, Zhi-Dong Zhou, Wei Zhou, Qinggen Xiong, Chang L. The Ubiquitin Ligase HERC2 promotes Ang II-induced cardiac hypertrophy via destabilization of MeCP2 to enhance Lin28a expression. Journal of cardiovascular pharmacology. 2024-11-05. PMID:39499120. |
conversely, cardiac specific overexpression of herc2 aggravated ang ii-induced cardiac hypertrophy in vitro and in vivo. |
2024-11-05 |
2024-11-08 |
Not clear |
| Bin Zhou, Hui-Fan Fu, Jiang-Feng Niu, Wei Deng, Fu-Mou Deng, Zhi-Dong Zhou, Wei Zhou, Qinggen Xiong, Chang L. The Ubiquitin Ligase HERC2 promotes Ang II-induced cardiac hypertrophy via destabilization of MeCP2 to enhance Lin28a expression. Journal of cardiovascular pharmacology. 2024-11-05. PMID:39499120. |
in this study, we observed that the expression and activity of herc2 was significantly upregulated in hypertrophic hearts and angiotensin ii (ang ii)-stimulated primary cardiomyocytes. |
2024-11-05 |
2024-11-08 |
Not clear |
| Bin Zhou, Hui-Fan Fu, Jiang-Feng Niu, Wei Deng, Fu-Mou Deng, Zhi-Dong Zhou, Wei Zhou, Qinggen Xiong, Chang L. The Ubiquitin Ligase HERC2 promotes Ang II-induced cardiac hypertrophy via destabilization of MeCP2 to enhance Lin28a expression. Journal of cardiovascular pharmacology. 2024-11-05. PMID:39499120. |
knockdown of herc2 in cardiomyocytes significantly alleviated the myocardial hypertrophy induced by ang ii. |
2024-11-05 |
2024-11-08 |
Not clear |
| Bin Zhou, Hui-Fan Fu, Jiang-Feng Niu, Wei Deng, Fu-Mou Deng, Zhi-Dong Zhou, Wei Zhou, Qinggen Xiong, Chang L. The Ubiquitin Ligase HERC2 promotes Ang II-induced cardiac hypertrophy via destabilization of MeCP2 to enhance Lin28a expression. Journal of cardiovascular pharmacology. 2024-11-05. PMID:39499120. |
knocking down lin28a attenuated ang ii-induced myocardial hypertrophy and abolished the increase in myocardial hypertrophy by overexpression of herc2. |
2024-11-05 |
2024-11-08 |
Not clear |
| Slava Malatiali, Mabayoje Oriow. Losartan is more effective than angiotensin (1-7) in preventing thyroxine-induced renal injury in the rat. Thyroid research. vol 17. issue 1. 2024-11-04. PMID:39491028. |
studies have shown that renal hypertrophy seen in experimental hyperthyroidism induced by thyroxine (t4) is due to angiotensin (ang) ii. |
2024-11-04 |
2024-11-06 |
rat |
| Mei-Ping Zhu, Bing-Yi Zhang, Ting Lian, Yuan-Jia Tan, Lin-Lin Chang, Pan Xu, Jin-Yi Zhang, Yan-Huan Du, Zhen-Yu Xiong, Qiong Du, Shi-Zhong Zhan. Involvement of mitochondrial TRPV3 in cardiac hypertrophy induced by pressure overload in rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 76. issue 5. 2024-10-29. PMID:39468807. |
rat h9c2 myocardial cells were treated with angiotensin ii (ang ii) to establish a hypertrophic myocardial cell model, and trpv3 expression was knocked down using trpv3 small interfering rna (sirna). |
2024-10-29 |
2024-10-31 |
rat |
| Yu Jiang, Wenyao Cai, Guangtao Lei, Guorong Cai, Qinghua Wu, Peng L. Deubiquitinase USP47 ameliorates cardiac hypertrophy through reducing protein O-GlcNAcylation. Journal of cardiovascular pharmacology. 2024-10-22. PMID:39436323. |
here, we observed that the expression level of deubiquitinase usp47 was increased in hypertrophic hearts and angiotensin ii (ang ii)-stimulated neonatal rat cardiomyocytes (nrcms). |
2024-10-22 |
2024-10-24 |
rat |