| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eduardo Nocchi, Sérgio Scalzo, Cibele Rocha-Resende, Pedro Almeida, Amanda Parreira, Kiany Miranda, Victor M Vidal, Robson A S Dos Santos, Silvia Guatimosi. The Mas agonist CGEN-856S prevents Ang II induced cardiomyocyte hypertrophy via nitric oxide production. Peptides. 2024-03-01. PMID:38428743. |
the mas agonist cgen-856s prevents ang ii induced cardiomyocyte hypertrophy via nitric oxide production. |
2024-03-01 |
2024-03-04 |
mouse |
| Eduardo Nocchi, Sérgio Scalzo, Cibele Rocha-Resende, Pedro Almeida, Amanda Parreira, Kiany Miranda, Victor M Vidal, Robson A S Dos Santos, Silvia Guatimosi. The Mas agonist CGEN-856S prevents Ang II induced cardiomyocyte hypertrophy via nitric oxide production. Peptides. 2024-03-01. PMID:38428743. |
in addition, cgen-856s prevented the ang ii induced hypertrophy and the nuclear translocation of grk5 in a culture model of rat neonatal cardiomyocytes. |
2024-03-01 |
2024-03-04 |
mouse |
| Eduardo Nocchi, Sérgio Scalzo, Cibele Rocha-Resende, Pedro Almeida, Amanda Parreira, Kiany Miranda, Victor M Vidal, Robson A S Dos Santos, Silvia Guatimosi. The Mas agonist CGEN-856S prevents Ang II induced cardiomyocyte hypertrophy via nitric oxide production. Peptides. 2024-03-01. PMID:38428743. |
in conclusion, we show that cgen-856s acting via receptor mas induces no raise to block ang ii induced cardiomyocyte hypertrophy. |
2024-03-01 |
2024-03-04 |
mouse |
| Qi-Qiang Zhang, Qing-Shan Chen, Fei Feng, Xiang Cao, Xiao-Fei Chen, Hai Zhan. Benzoylaconitine: A promising ACE2-targeted agonist for enhancing cardiac function in heart failure. Free radical biology & medicine. 2024-02-18. PMID:38369076. |
in this study, benzoylaconitine inhibited ang ii-induced cell hypertrophy and fibrosis in rat primary cardiomyocytes and rat fibroblasts, while attenuating cardiac function and cardiac remodeling in tac mice. |
2024-02-18 |
2024-02-21 |
mouse |
| Ya-Che Lee, Yeong-Chin Jou, Wan-Ching Chou, Kun-Ling Tsai, Cheng-Huang Shen, Shin-Da Le. Ellagic acid protects against angiotensin II-induced hypertrophic responses through ROS-mediated MAPK pathway in H9c2 cells. Environmental toxicology. 2024-02-15. PMID:38356441. |
this hypertrophic event of the heart is mediated by the interaction of ang type 1 receptors (at-r1), thereby modulating nadph oxidase activity in cardiomyocytes, which alters redox status in cardiomyocytes. |
2024-02-15 |
2024-02-17 |
Not clear |
| Yitong Wang, Xiangbo An, Feng Wang, Yinong Jian. Ginsenoside RH4 inhibits Ang II-induced myocardial remodeling by interfering with NFIL3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-15. PMID:38359490. |
in this study, a myocardial remodeling model was established using angiotensin (ang) ii, and the inhibitory effect of rh4 on myocardial hypertrophy and remodeling induced by ang ii was investigated using pathological staining and quantitative polymerase chain reaction (qpcr). |
2024-02-15 |
2024-02-18 |
mouse |
| Yitong Wang, Xiangbo An, Feng Wang, Yinong Jian. Ginsenoside RH4 inhibits Ang II-induced myocardial remodeling by interfering with NFIL3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-15. PMID:38359490. |
the findings indicated that rh4 could inhibit myocardial hypertrophy, inflammatory fibrosis, and oxidative stress induced by ang ii, suggesting potential cardiovascular protection effects. |
2024-02-15 |
2024-02-18 |
mouse |
| Xueqian Ouyang, Wei Chen, Guolong Peng, Huimei Liu, Sisi Fan, Qin Li, Liwen Wang, Linxi Chen, Lanfang L. 1,12-cyclic apelin-12 ameliorates Ang II and Apelin-13-induced cardiac hypertrophy by reducing mitochondrial oxidative damage. Chinese medical journal. 2024-02-07. PMID:38321846. |
1,12-cyclic apelin-12 ameliorates ang ii and apelin-13-induced cardiac hypertrophy by reducing mitochondrial oxidative damage. |
2024-02-07 |
2024-02-09 |
Not clear |
| Lei Shi, Yanzhen Tan, Wenying Zheng, Guojie Cao, Haitao Zhou, Panpan Li, Jun Cui, Yujie Song, Lele Feng, Hong Li, Wenju Shan, Bing Zhang, Wei Y. CTRP3 alleviates mitochondrial dysfunction and oxidative stress injury in pathological cardiac hypertrophy by activating UPRmt via the SIRT1/ATF5 axis. Cell death discovery. vol 10. issue 1. 2024-01-26. PMID:38278820. |
tac or ang ii resulted in compensatory activation of uprmt, but this was not sufficient to counteract pathologic cardiac hypertrophy. |
2024-01-26 |
2024-01-29 |
mouse |
| Min Jia, Wenxue Liu, Keyin Zhang, Zhigang Wang, Ruisha Li, Jun Pan, Jianjun Yang, Dongjin Wan. Larixyl acetate, a TRPC6 inhibitor, attenuates pressure overload‑induced heart failure in mice. Molecular medicine reports. vol 29. issue 3. 2024-01-26. PMID:38275127. |
the results indicated that treatment with tac or ang ii leads to significant hypertrophy and dysfunction of the heart or h9c2 cells, accompanied by an increase in er stress, apoptosis and activation of the mtor signaling pathway, and a decrease in autophagy. |
2024-01-26 |
2024-01-28 |
mouse |
| Yi-Jiang Liu, Jia-Jia Xu, Cui Yang, Yan-Lin Li, Min-Wei Chen, Shi-Xiao Liu, Xiang-Hui Zheng, Ping Luo, Rui Li, Di Xiao, Zhong-Gui Sha. Muscone inhibits angiotensin II-induced cardiac hypertrophy through the STAT3, MAPK and TGF-β/SMAD signaling pathways. Molecular biology reports. vol 51. issue 1. 2023-12-29. PMID:38158445. |
although many studies have confirmed the cardioprotective effects of muscone, the effects of muscone on cardiac hypertrophy and its potential mechanisms are unclear.the aim of the present study was to investigate the effect of muscone on angiotensin (ang) ii-induced cardiac hypertrophy. |
2023-12-29 |
2024-01-05 |
Not clear |
| Poonam, Shashi Chaudhar. Interactions between AT1R and GRKs: the determinants for activation of signaling pathways involved in blood pressure regulation. Molecular biology reports. vol 51. issue 1. 2023-12-29. PMID:38158508. |
the structural insights and mutational studies of ang ii-at1r have brought about the vision to design ang ii analogs that selectively activate the pathways with beneficial and cardioprotective effects such as cell survival and hinder the deleterious effects such as hypertrophy and cell death. |
2023-12-29 |
2024-01-05 |
Not clear |
| Lintao Wang, Suya Zhang, Hongxia Liu, Li Gao, Lu He, Yue Chen, Junsheng Zhang, Miaomiao Yang, Chaoyong H. STING activation in cardiomyocytes drives hypertrophy-associated heart failure via NF-κB-mediated inflammatory response. Biochimica et biophysica acta. Molecular basis of disease. 2023-12-24. PMID:38142758. |
furthermore, deleting or pharmacologically inhibiting sting attenuated cardiac hypertrophy and dysfunction in tac or ang ii-treated mice. |
2023-12-24 |
2023-12-27 |
mouse |
| Zhenyu Feng, Ningning Zhang, Jie Bai, Qiu-Yue Lin, Yunpeng Xie, Yun-Long Xi. Biochanin A inhibits cardiac hypertrophy and fibrosis in vivo and in vitro. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 170. 2023-12-13. PMID:38091641. |
bca inhibited ang ii-induced cell hypertrophy and oxidative stress in nrcms in vitro and ang ii-induced cf migration, proliferation, and collagen secretion. |
2023-12-13 |
2023-12-17 |
mouse |
| Qian Xu, Kunping Zhuo, Xiaotian Zhang, Yanru Zhen, Limin Liu, Lu Zhang, Yufan Gu, Hui Jia, Qing Chen, Meixi Liu, Jiawei Dong, Ming-Sheng Zho. The role of angiotensin II activation of yes-associated protein/PDZ-binding motif signaling in hypertensive cardiac and vascular remodeling. European journal of pharmacology. vol 962. 2023-12-12. PMID:38061470. |
treatment with verteporfin significantly reduced ang ii-induced cardiac and vascular hypertrophy with a mild reduction in systolic blood pressure (sbp), verteporfin attenuated ang ii-induced cardiac and aortic fibrosis with the inhibition of transform growth factor (tgf)β/smad2/3 fibrotic signaling and extracellular matrix collagen i deposition. |
2023-12-12 |
2023-12-17 |
Not clear |
| Xiaoyan Lin, Hailin Zhang, Yong Chu, Yuze Zhang, Changsheng Xu, Hong Xie, Qinyun Ruan, Jinxiu Lin, Chun-Kai Huang, Dajun Cha. Honokiol ameliorates angiotensin II-induced cardiac hypertrophy by promoting dissociation of the Nur77-LKB1 complex and activating the AMPK pathway. Journal of cellular and molecular medicine. 2023-11-20. PMID:37985436. |
this study aims to investigate the effect of hnk on angiotensin ii (ang ii)-induced myocardial hypertrophy and elucidate the underlying mechanisms. |
2023-11-20 |
2023-11-29 |
rat |
| Xiaoyan Lin, Hailin Zhang, Yong Chu, Yuze Zhang, Changsheng Xu, Hong Xie, Qinyun Ruan, Jinxiu Lin, Chun-Kai Huang, Dajun Cha. Honokiol ameliorates angiotensin II-induced cardiac hypertrophy by promoting dissociation of the Nur77-LKB1 complex and activating the AMPK pathway. Journal of cellular and molecular medicine. 2023-11-20. PMID:37985436. |
our results showed that hnk treatment protected against ang ii-induced myocardial hypertrophy, fibrosis and dysfunction in vivo and inhibited ang ii-induced hypertrophy in neonatal rat ventricular myocytes in vitro. |
2023-11-20 |
2023-11-29 |
rat |
| Chanyuan Lv, Liuyi Zhou, Yongkang Meng, Haitao Yuan, Jing Gen. PKD knockdown mitigates Ang II-induced cardiac hypertrophy and ferroptosis via the JNK/P53 signaling pathway. Cellular signalling. 2023-11-16. PMID:37972803. |
pkd knockdown mitigates ang ii-induced cardiac hypertrophy and ferroptosis via the jnk/p53 signaling pathway. |
2023-11-16 |
2023-11-20 |
Not clear |
| Shinya Taguchi, Kengo Azushima, Takahiro Yamaji, Toru Suzuki, Eriko Abe, Shohei Tanaka, Keigo Hirota, Shunichiro Tsukamoto, Ryutaro Morita, Ryu Kobayashi, Sho Kinguchi, Akio Yamashita, Hiromichi Wakui, Kouichi Tamur. Angiotensin II type 1 receptor-associated protein deletion combined with angiotensin II stimulation accelerates the development of diabetic kidney disease in mice on a C57BL/6 strain. Hypertension research : official journal of the Japanese Society of Hypertension. 2023-11-13. PMID:37957242. |
however, a combination of atrap deletion with ang ii stimulation accelerated the development of dkd as manifested by overt albuminuria, glomerular hypertrophy, podocyte loss, mesangial expansion, kidney interstitial fibrosis and functional insufficiency, concomitant with increased angiotensinogen and at1r expression in the kidneys. |
2023-11-13 |
2023-11-20 |
mouse |
| Si-Ting Xu, Yue-Xin Zhang, Si-Ling Liu, Fang Liu, Jian-Tao Y. Exosomes derived from cardiac fibroblasts with angiotensin II stimulation provoke hypertrophy and autophagy inhibition in cardiomyocytes. Biochemical and biophysical research communications. vol 682. 2023-10-12. PMID:37826943. |
these findings highlight a novel role of ang ii-cfs-exosomes in suppressing cardiomyocyte autophagy, which may help to better understand the pathogenesis of cardiac hypertrophy. |
2023-10-12 |
2023-10-15 |
mouse |