| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucas B Comeras, Noa Hörmer, Pradeepa Mohan Bethuraj, Ramon O Tasa. NPY Released From GABA Neurons of the Dentate Gyrus Specially Reduces Contextual Fear Without Affecting Cued or Trace Fear. Frontiers in synaptic neuroscience. vol 13. 2021-06-15. PMID:34122036. |
importantly, npy in the dorsal dg was not only expressed in somatostatin neurons, but also in parvalbumin-positive basket cells and axoaxonic cells, indicating intense feedback and feedforward modulation of hippocampal signaling and precise curtailing of neuronal engrams. |
2021-06-15 |
2023-08-13 |
Not clear |
| Lucas B Comeras, Noa Hörmer, Pradeepa Mohan Bethuraj, Ramon O Tasa. NPY Released From GABA Neurons of the Dentate Gyrus Specially Reduces Contextual Fear Without Affecting Cued or Trace Fear. Frontiers in synaptic neuroscience. vol 13. 2021-06-15. PMID:34122036. |
thus, these findings suggest that co-release of npy from specific interneuron populations of the dorsal dg modifies dedicated aspects of hippocampal processing by sharpening the activation of neural engrams and the consecutive fear response. |
2021-06-15 |
2023-08-13 |
Not clear |
| Gislaine Olescowicz, Tuane B Sampaio, Cristine de Paula Nascimento-Castro, Patricia S Brocardo, Joana Gil-Mohapel, Ana Lúcia S Rodrigue. Protective Effects of Agmatine Against Corticosterone-Induced Impairment on Hippocampal mTOR Signaling and Cell Death. Neurotoxicity research. vol 38. issue 2. 2021-06-14. PMID:32399718. |
treatment on the levels of phosphorylated mtor (p-mtor), neuronal death, and overall volume in the hippocampal dentate gyrus (dg) of mice exposed to chronic corticosterone (20 mg/kg, p.o.) |
2021-06-14 |
2023-08-13 |
mouse |
| Gislaine Olescowicz, Tuane B Sampaio, Cristine de Paula Nascimento-Castro, Patricia S Brocardo, Joana Gil-Mohapel, Ana Lúcia S Rodrigue. Protective Effects of Agmatine Against Corticosterone-Induced Impairment on Hippocampal mTOR Signaling and Cell Death. Neurotoxicity research. vol 38. issue 2. 2021-06-14. PMID:32399718. |
agmatine, similarly to fluoxetine, was capable of reversing this alteration in the entire dg, an effect more evident in the ventral portion of the hippocampus. |
2021-06-14 |
2023-08-13 |
mouse |
| Justin J Botterill, K Yaragudri Vinod, Kathleen J Gerencer, Cátia M Teixeira, John J LaFrancois, Helen E Scharfma. Bidirectional Regulation of Cognitive and Anxiety-like Behaviors by Dentate Gyrus Mossy Cells in Male and Female Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 11. 2021-06-11. PMID:33472828. |
the dentate gyrus (dg) of the hippocampus is important for cognition and behavior. |
2021-06-11 |
2023-08-13 |
mouse |
| Kyle R Jensen, Coralie Berthoux, Kaoutsar Nasrallah, Pablo E Castill. Multiple cannabinoid signaling cascades powerfully suppress recurrent excitation in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 4. 2021-06-09. PMID:33468648. |
by targeting the ipsi- and contralateral dentate gyrus (dg) along the dorsoventral axis of the hippocampus, mcs form an extensive recurrent excitatory circuit (gc-mc-gc) whose dysregulation can promote epilepsy. |
2021-06-09 |
2023-08-13 |
Not clear |
| Max Rudolph, Christian W Schmeer, Madlen Günther, Florus Woitke, Carolin Kathner-Schaffert, Lina Karapetow, Julia Lindner, Thomas Lehmann, Gustav Jirikowski, Otto W Witte, Christoph Redecker, Silke Keine. Microglia-mediated phagocytosis of apoptotic nuclei is impaired in the adult murine hippocampus after stroke. Glia. vol 69. issue 8. 2021-06-09. PMID:33942391. |
here, we evaluated the effect of a prefrontal stroke lesion on the phagocytic activity of microglia in the dentate gyrus (dg) of the hippocampus. |
2021-06-09 |
2023-08-13 |
mouse |
| Dan Wu, Xiaomeng Xu, Na Sun, Dongmei Li, Beiwei Zhu, Songyi Li. AGLPM and QMDDQ peptides exert a synergistic action on memory improvement against scopolamine-induced amnesiac mice. Food & function. vol 11. issue 12. 2021-06-07. PMID:33242042. |
furthermore, combination treatment with qmddq and aglpm could significantly reduce the acetylcholinesterase (ache) level and increase the acetylcholine (ach) level in the hippocampus, and noticeably improve the pathological morphology of the neuron cells in hippocampal regions ca1 and ca2 and dentate gyrus (dg). |
2021-06-07 |
2023-08-13 |
mouse |
| Luofang Peng, Maoen Zhu, Yong Yang, Feng Lu, Xian Liu, Qulian Guo, Tao Zhon. Repeated Neonatal Isoflurane Exposure is Associated with Higher Susceptibility to Chronic Variable Stress-induced Behavioural and Neuro-inflammatory Alterations. Neuroscience. vol 465. 2021-06-04. PMID:33951503. |
in mice experiencing serial neonatal isoflurane exposure, we detected a significant enhancement in anxiety levels following cvs procedures, together with enhanced neuronal activity, and exacerbated neuroinflammation in the basolateral amygdaloid nuclei (bla) and hippocampal dentate gyrus (dg) regions. |
2021-06-04 |
2023-08-13 |
mouse |
| Minlan Yuan, Hongru Zhu, Yuchen Li, Fenfen Ge, Su Lui, Qiyong Gong, Changjian Qiu, Huan Song, Wei Zhan. The DRD2 Taq1A polymorphism moderates the effect of PTSD symptom severity on the left hippocampal CA3 volume: a pilot study. Psychopharmacology. 2021-06-04. PMID:34086098. |
the hippocampus, especially the ca1, ca3, and dentate gyrus (dg) subfields, is reported to be associated with post-traumatic stress disorder (ptsd) after trauma. |
2021-06-04 |
2023-08-13 |
Not clear |
| Minlan Yuan, Hongru Zhu, Yuchen Li, Fenfen Ge, Su Lui, Qiyong Gong, Changjian Qiu, Huan Song, Wei Zhan. The DRD2 Taq1A polymorphism moderates the effect of PTSD symptom severity on the left hippocampal CA3 volume: a pilot study. Psychopharmacology. 2021-06-04. PMID:34086098. |
the aim of this study is to examine whether the dopamine d2 receptor (drd2) taq1a polymorphism, which is associated with both hippocampal function and ptsd, moderated the association between ptsd severity and hippocampal ca1, ca3 and dg volumes. |
2021-06-04 |
2023-08-13 |
Not clear |
| Xinjian Zhu, Yuanyuan Yao, Jiurong Yang, Qiyue Ge, Diejing Niu, Xiufang Liu, Chenchen Zhang, Guangming Gan, Aifeng Zhang, Honghong Ya. Seizure-induced neuroinflammation contributes to ectopic neurogenesis and aggressive behavior in pilocarpine-induced status epilepticus mice. Neuropharmacology. vol 170. 2021-06-03. PMID:32179291. |
neurogenesis persists throughout life in the hippocampal dentate gyrus (dg) to maintain proper brain function. |
2021-06-03 |
2023-08-13 |
mouse |
| Xinjian Zhu, Yuanyuan Yao, Jiurong Yang, Qiyue Ge, Diejing Niu, Xiufang Liu, Chenchen Zhang, Guangming Gan, Aifeng Zhang, Honghong Ya. Seizure-induced neuroinflammation contributes to ectopic neurogenesis and aggressive behavior in pilocarpine-induced status epilepticus mice. Neuropharmacology. vol 170. 2021-06-03. PMID:32179291. |
neuroinflammatory responses are well known to affect neurogenesis and lead to aberrant reorganization of neural networks in the hippocampal dg. |
2021-06-03 |
2023-08-13 |
mouse |
| Xinjian Zhu, Yuanyuan Yao, Jiurong Yang, Qiyue Ge, Diejing Niu, Xiufang Liu, Chenchen Zhang, Guangming Gan, Aifeng Zhang, Honghong Ya. Seizure-induced neuroinflammation contributes to ectopic neurogenesis and aggressive behavior in pilocarpine-induced status epilepticus mice. Neuropharmacology. vol 170. 2021-06-03. PMID:32179291. |
more importantly, these proliferating and surviving newborn granular cells are largely ectopically located in the hippocampal dg hilus region. |
2021-06-03 |
2023-08-13 |
mouse |
| Tetsade C B Piermartiri, Beatriz Dos Santos, Fernanda G Q Barros-Aragão, Rui D Prediger, Carla Inês Tasc. Guanosine Promotes Proliferation in Neural Stem Cells from Hippocampus and Neurogenesis in Adult Mice. Molecular neurobiology. vol 57. issue 9. 2021-06-03. PMID:32592125. |
the intraperitoneal treatment of adult c57bl/6 mice with guanosine (8 mg/kg) for 26 days increased the number of dividing bromodeoxyuridine (brdu)-positive cells and also increased neurogenesis, as identified by measuring doublecortin (dcx)-positive cells in the dentate gyrus (dg) of the hippocampus. |
2021-06-03 |
2023-08-13 |
mouse |
| Milenna T van Dijk, Jiook Cha, David Semanek, Natalie Aw, Marc J Gameroff, Eyal Abraham, Priya J Wickramaratne, Myrna M Weissman, Jonathan Posner, Ardesheer Talat. Altered Dentate Gyrus Microstructure in Individuals at High Familial Risk for Depression Predicts Future Symptoms. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 6. issue 1. 2021-06-03. PMID:32855106. |
altered hippocampal, and specifically dentate gyrus (dg), structure and function may be involved in depression development. |
2021-06-03 |
2023-08-13 |
Not clear |
| Bumwhee Lee, Shree Panda, Hye Young Le. Primary Ciliary Deficits in the Dentate Gyrus of Fragile X Syndrome. Stem cell reports. vol 15. issue 2. 2021-06-02. PMID:32735823. |
here, we found that the number of primary cilia in fmr1 ko mice is reduced, specifically in the dg of the hippocampus. |
2021-06-02 |
2023-08-13 |
mouse |
| Hui Wang, Xiaxia Xu, Xinxin Xu, Jing Gao, Tao Zhan. Enriched Environment and Social Isolation Affect Cognition Ability via Altering Excitatory and Inhibitory Synaptic Density in Mice Hippocampus. Neurochemical research. vol 45. issue 10. 2021-06-01. PMID:32748366. |
long term potentiation (ltp), depotentiation (dep) and local field potentials were recorded in the hippocampal perforant pathway and dentate gyrus (dg) region. |
2021-06-01 |
2023-08-13 |
mouse |
| Hui Wang, Xiaxia Xu, Xinxin Xu, Jing Gao, Tao Zhan. Enriched Environment and Social Isolation Affect Cognition Ability via Altering Excitatory and Inhibitory Synaptic Density in Mice Hippocampus. Neurochemical research. vol 45. issue 10. 2021-06-01. PMID:32748366. |
the data showed that ee enhanced the ability of spatial learning, reversal learning and memory as well as ltp/dep in the hippocampal dg region. |
2021-06-01 |
2023-08-13 |
mouse |
| Julie E Anderson, Madison Trujillo, Taylor McElroy, Thomas Groves, Tyler Alexander, Frederico Kiffer, Antiño R Alle. Early Effects of Cyclophosphamide, Methotrexate, and 5-Fluorouracil on Neuronal Morphology and Hippocampal-Dependent Behavior in a Murine Model. Toxicological sciences : an official journal of the Society of Toxicology. vol 173. issue 1. 2021-05-27. PMID:31651976. |
further analysis revealed decreases in arborization across the hippocampus (dg, ca1 apical and basal, ca3 apical and basal). |
2021-05-27 |
2023-08-13 |
mouse |