| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yue Li, Yuming Zhao, Chong Gao, Meiling Wu, Kwok-Fai So, Yao Tong, Jiangang She. Caveolin-1 Derived from Brain Microvascular Endothelial Cells Inhibits Neuronal Differentiation of Neural Stem/Progenitor Cells In Vivo and In Vitro. Neuroscience. vol 448. 2021-05-14. PMID:32976986. |
(2) cav-1 knockout mice exhibited the increased dcx and vegf at the granular cell layers of hippocampal dg in post-ischemic brains. |
2021-05-14 |
2023-08-13 |
mouse |
| Stephen Beesley, Thomas Sullenberger, Roshan Ailani, Cameron D'Orio, Mathew S Crockett, Sanjay S Kuma. d-Serine Intervention In The Medial Entorhinal Area Alters TLE-Related Pathology In CA1 Hippocampus Via The Temporoammonic Pathway. Neuroscience. vol 453. 2021-05-14. PMID:33197499. |
entrainment of the hippocampus by the medial entorhinal area (mea) in temporal lobe epilepsy (tle), the most common type of drug-resistant epilepsy in adults, is believed to be mediated primarily through the perforant pathway (pp), which connects stellate cells in layer (l) ii of the mea with granule cells of the dentate gyrus (dg) to drive the hippocampal tri-synaptic circuit. |
2021-05-14 |
2023-08-13 |
rat |
| J Bryce Ortiz, Jason Newbern, Cheryl D Conra. Chronic stress has different immediate and delayed effects on hippocampal calretinin- and somatostatin-positive cells. Hippocampus. vol 31. issue 2. 2021-05-14. PMID:33241879. |
in contrast, chronic stress reduced the expression of cr+ in the ca3 region of the hippocampus in both males and females, with robust reductions in the dg region of males, but not females, and these changes reversed following a rest period. |
2021-05-14 |
2023-08-13 |
mouse |
| Poonam Mishra, Rishikesh Narayana. Heterogeneities in intrinsic excitability and frequency-dependent response properties of granule cells across the blades of the rat dentate gyrus. Journal of neurophysiology. vol 123. issue 2. 2021-05-12. PMID:31913748. |
the dentate gyrus (dg), the input gate to the hippocampus proper, is anatomically segregated into three different sectors, namely, the suprapyramidal blade, the crest region, and the infrapyramidal blade. |
2021-05-12 |
2023-08-13 |
rat |
| Yuting Gao, Miaomiao Cui, Sijin Zhong, Chenyao Feng, Alexander Kenechukwu Nwobodo, Bin Chen, Yuanjian Song, Yulan Wan. Dihydroartemisinin ameliorates LPS-induced neuroinflammation by inhibiting the PI3K/AKT pathway. Metabolic brain disease. vol 35. issue 4. 2021-05-11. PMID:32152798. |
gfap fluorescent staining: compared with the control group, the corresponding reactivity of positive cells in the lps-induced group was increased in the ca1-ca3 and dg regions of the hippocampus; compared with the lps-induced mice, cells in the lps + dha group showed significantly reduced reactivity (gfap). |
2021-05-11 |
2023-08-13 |
mouse |
| Julia von Wittgenstein, Fang Zheng, Marie-Theres Wittmann, Elli-Anna Balta, Fulvia Ferrazzi, Iris Schäffner, Benjamin M Häberle, Maria J Valero-Aracama, Muriel Koehl, Carlos J Miranda, Brian K Kaspar, Arif B Ekici, André Reis, Djoher Nora Abrous, Christian Alzheimer, D Chichung Li. Sox11 is an Activity-Regulated Gene with Dentate-Gyrus-Specific Expression Upon General Neural Activation. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 6. 2021-05-04. PMID:32080705. |
strikingly, sox11 induction was restricted to the dentate gyrus (dg) of the hippocampus. |
2021-05-04 |
2023-08-13 |
mouse |
| Mohammadreza Shirazy, Kimia RayatSanati, Shole Jamali, Fereshteh Motamedi, Abbas Haghparas. Role of orexinergic receptors in the dentate gyrus of the hippocampus in the acquisition and expression of morphine-induced conditioned place preference in rats. Behavioural brain research. vol 379. 2021-04-30. PMID:31711894. |
it has been demonstrated in previous that orexinergic receptors are expressed in the dentate gyrus (dg) region of the hippocampus, which receives projections of lh orexinergic neurons. |
2021-04-30 |
2023-08-13 |
rat |
| Jennie C Gardner, Svyatoslav V Dvoretskiy, Yanyu Yang, Sanjana Venkataraman, Dominica A Lange, Shiping Li, Alexandria L Boppart, Noah Kim, Catarina Rendeiro, Marni D Boppart, Justin S Rhode. Electrically stimulated hind limb muscle contractions increase adult hippocampal astrogliogenesis but not neurogenesis or behavioral performance in male C57BL/6J mice. Scientific reports. vol 10. issue 1. 2021-04-30. PMID:33168868. |
acute neuronal activation of the dentate gyrus (dg) using cfos immunohistochemistry was measured as a negative control to confirm that the muscle contractions did not activate the hippocampus, and in agreement, no dg activation was observed. |
2021-04-30 |
2023-08-13 |
mouse |
| Jennie C Gardner, Svyatoslav V Dvoretskiy, Yanyu Yang, Sanjana Venkataraman, Dominica A Lange, Shiping Li, Alexandria L Boppart, Noah Kim, Catarina Rendeiro, Marni D Boppart, Justin S Rhode. Electrically stimulated hind limb muscle contractions increase adult hippocampal astrogliogenesis but not neurogenesis or behavioral performance in male C57BL/6J mice. Scientific reports. vol 10. issue 1. 2021-04-30. PMID:33168868. |
results demonstrate that muscle contractions alone, in absence of dg activation, are sufficient to increase adult hippocampal astrogliogenesis, but not neurogenesis or behavioral performance in mice. |
2021-04-30 |
2023-08-13 |
mouse |
| Fatma Z Sakhri, Naoki Adachi, Sakina Zerizer, Yusuke Ohashi, Hideshi Ikemoto, Mana Tsukada, Zahia Kabouche, Tadashi Hisamitsu, Masataka Sunagaw. Behavioral and neurological improvement by Cydonia oblonga fruit extract in chronic immobilization stress rats. Phytotherapy research : PTR. vol 35. issue 4. 2021-04-30. PMID:33205508. |
a daily 6 hr exposure to chronic immobilization stress (cis) for 21 consecutive days induced anxiety- and depressive-like behaviors in rats' concomitant with decreased weight gain and increased plasma corticosterone (cort) levels, rats also showed atrophy in the ca3 subregion of the hippocampus and a decreased number of ki67 and dcx positive cells in the dentate gyrus (dg). |
2021-04-30 |
2023-08-13 |
rat |
| Seyed Asaad Karimi, Somayeh Komaki, Masoumeh Taheri, Ghazaleh Omidi, Masoumeh Kourosh-Arami, Iraj Salehi, Alireza Komak. Effects of the hydroalcoholic extract of Rosa damascena on hippocampal long-term potentiation in rats fed high-fat diet. The journal of physiological sciences : JPS. vol 71. issue 1. 2021-04-30. PMID:33926383. |
this study was carried out to determine the beneficial effect of hydroalcoholic extract of r. damascena on in vivo hippocampal synaptic plasticity (long-term potentiation, ltp) in the perforant pathway (pp)-dentate gyrus (dg) pathway in rats fed with an hfd. |
2021-04-30 |
2023-08-13 |
rat |
| Gemma Huguet, Elisabet Kádár, Noelia Serrano, Carles Tapias-Espinosa, Soleil García-Brito, Ignacio Morgado-Bernal, Laura Aldavert-Vera, Pilar Segura-Torre. Rewarding deep brain stimulation at the medial forebrain bundle favours avoidance conditioned response in a remote memory test, hinders extinction and increases neurogenesis. Behavioural brain research. vol 378. 2021-04-29. PMID:31629001. |
the present work aims to test whether the combination of these two forms of icss administration can cause a greater persistence of the facilitating effect on remote retention and affect neurogenesis in the dentate gyrus (dg) of the hippocampus. |
2021-04-29 |
2023-08-13 |
human |
| Thomas Frodl, Katharina Strehl, Angela Carballedo, Leonardo Tozzi, Myles Doyle, Francesco Amico, John Gormley, Grace Lavelle, Veronica O'Kean. Aerobic exercise increases hippocampal subfield volumes in younger adults and prevents volume decline in the elderly. Brain imaging and behavior. vol 14. issue 5. 2021-04-27. PMID:30927200. |
exercise improves both physical and mental health and increases neurogenesis in the dendate gyrus (dg) of the hippocampus. |
2021-04-27 |
2023-08-13 |
human |
| Thomas Frodl, Katharina Strehl, Angela Carballedo, Leonardo Tozzi, Myles Doyle, Francesco Amico, John Gormley, Grace Lavelle, Veronica O'Kean. Aerobic exercise increases hippocampal subfield volumes in younger adults and prevents volume decline in the elderly. Brain imaging and behavior. vol 14. issue 5. 2021-04-27. PMID:30927200. |
the aim of this study was to examine whether exercising, as compared to no change in regular physical activity, would impact on hippocampal volume, and in particular the core hippocampal structures, dg and cornu ammonis (ca) subfields, and whether any changes would be moderated by age. |
2021-04-27 |
2023-08-13 |
human |
| Jinxuan Cheng, Federico Scala, Francisco A Blanco, Sanyong Niu, Karen Firozi, Laura Keehan, Shalaka Mulherkar, Emmanouil Froudarakis, Lingyong Li, Joseph G Duman, Xiaolong Jiang, Kimberley F Tolia. The Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 6. 2021-04-27. PMID:33328293. |
the dentate gyrus (dg) controls information flow into the hippocampus and is critical for learning, memory, pattern separation, and spatial coding, while dg dysfunction is associated with neuropsychiatric disorders. |
2021-04-27 |
2023-08-13 |
Not clear |
| Jinxuan Cheng, Federico Scala, Francisco A Blanco, Sanyong Niu, Karen Firozi, Laura Keehan, Shalaka Mulherkar, Emmanouil Froudarakis, Lingyong Li, Joseph G Duman, Xiaolong Jiang, Kimberley F Tolia. The Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 6. 2021-04-27. PMID:33328293. |
in the hippocampus, tiam1 is predominantly expressed in the dg throughout life. |
2021-04-27 |
2023-08-13 |
Not clear |
| Dong Sun, Leena Milibari, Jin-Xiu Pan, Xiao Ren, Ling-Ling Yao, Yang Zhao, Chen Shen, Wen-Bing Chen, Fu-Lei Tang, Daehoon Lee, Jun-Shi Zhang, Lin Mei, Wen-Cheng Xion. Critical Roles of Embryonic Born Dorsal Dentate Granule Neurons for Activity-Dependent Increases in BDNF, Adult Hippocampal Neurogenesis, and Antianxiety-like Behaviors. Biological psychiatry. vol 89. issue 6. 2021-04-23. PMID:33183762. |
dentate gyrus (dg), a "gate" that controls information flow into the hippocampus, plays important roles in regulating both cognitive (e.g., spatial learning and memory) and mood behaviors. |
2021-04-23 |
2023-08-13 |
Not clear |
| Rocío Guerrero-Bautista, Aurelio Franco-García, Juana M Hidalgo, Francisco José Fernández-Gómez, Bruno Ribeiro Do Couto, M Victoria Milanés, Cristina Núñe. Distinct Regulation of Dopamine D3 Receptor in the Basolateral Amygdala and Dentate Gyrus during the Reinstatement of Cocaine CPP Induced by Drug Priming and Social Stress. International journal of molecular sciences. vol 22. issue 6. 2021-04-21. PMID:33803578. |
cocaine relapse engages the activity of memory-related nuclei, such as the basolateral amygdala (bla) and the hippocampal dentate gyrus (dg), which are responsible for emotional and episodic memories. |
2021-04-21 |
2023-08-13 |
Not clear |
| Dan-Ying Wang, An-Feng Luo, Qing-Ran Bai, Xiao-Li Gong, Yan Zheng, Qin Shen, Xiao-Ling Hu, Xiao-Min Wan. VCAM1 Labels a Subpopulation of Neural Stem Cells in the Adult Hippocampus and Contributes to Spatial Memory. Stem cell reports. vol 14. issue 6. 2021-04-19. PMID:32521248. |
active neural stem cells (anscs) and quiescent neural stem cells (qnscs) are two distinct subpopulations found in the adult hippocampal dentate gyrus (dg). |
2021-04-19 |
2023-08-13 |
mouse |
| Wei Ge, Chao Ren, Lei Xing, Lina Guan, Caiyi Zhang, Xuwen Sun, Guoping Wang, Haichen Niu, Sen Qu. Ginkgo biloba extract improves cognitive function and increases neurogenesis by reducing Aβ pathology in 5×FAD mice. American journal of translational research. vol 13. issue 3. 2021-04-13. PMID:33841671. |
after consecutive 4-month injections, mice were tested in learning memory tasks, aβ, and neurogenesis in the dentate gyrus (dg) of hippocampus and morphological characteristics of neurons in dg of hippocampus. |
2021-04-13 |
2023-08-13 |
mouse |