| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna-Lena Hillje, Elisabeth Beckmann, Maria A S Pavlou, Christian Jaeger, Maria P Pacheco, Thomas Sauter, Jens C Schwamborn, Lars Lewejohan. The neural stem cell fate determinant TRIM32 regulates complex behavioral traits. Frontiers in cellular neuroscience. vol 9. 2015-04-08. PMID:25852471. |
in mammals, new neurons are generated throughout the entire lifespan in two restricted areas of the brain, the dentate gyrus (dg) of the hippocampus and the subventricular zone (svz)-olfactory bulb (ob) system. |
2015-04-08 |
2023-08-13 |
mouse |
| C A Bostrom, N-M Majaess, K Morch, E White, B D Eadie, B R Christi. Rescue of NMDAR-dependent synaptic plasticity in Fmr1 knock-out mice. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 1. 2015-04-06. PMID:23968838. |
we report that a loss of fmrp leads to impairments in n-methyl-d-aspartate receptor (nmdar)-dependent synaptic plasticity in the dentate gyrus (dg), but not in the cornu ammonis area 1 (ca1) subregion of the hippocampus of adult mice. |
2015-04-06 |
2023-08-12 |
mouse |
| Erlend Bøen, Lars T Westlye, Torbjørn Elvsåshagen, Benjamin Hummelen, Per K Hol, Birgitte Boye, Stein Andersson, Sigmund Karterud, Ulrik F Mal. Smaller stress-sensitive hippocampal subfields in women with borderline personality disorder without posttraumatic stress disorder. Journal of psychiatry & neuroscience : JPN. vol 39. issue 2. 2015-04-02. PMID:24309162. |
based on the putative role of stressful life events as vulnerability factors for bpd, we hypothesized that patients with bpd would exhibit reduced volumes for the stress-sensitive dentate gyrus (dg) and the cornu ammonis (ca) 3 subfields volumes, and that these volumes would be associated with traumatic childhood experiences. |
2015-04-02 |
2023-08-12 |
human |
| Gang Li, Ting Liu, Xiangqian Kong, Lei Wang, Xing Ji. Hippocampal glycogen synthase kinase 3β is critical for the antidepressant effect of cyclin-dependent kinase 5 inhibitor in rats. Journal of molecular neuroscience : MN. vol 54. issue 1. 2015-04-01. PMID:24563226. |
evidence of previous study showed that chronic inhibition of cdk5 in hippocampal dentate gyrus (dg) blocked the development of depressive-like symptoms, suggesting that cdk5 plays a role in development of depression. |
2015-04-01 |
2023-08-12 |
rat |
| Sloka S Iyengar, John J LaFrancois, Daniel Friedman, Liam J Drew, Christine A Denny, Nesha S Burghardt, Melody V Wu, Jenny Hsieh, René Hen, Helen E Scharfma. Suppression of adult neurogenesis increases the acute effects of kainic acid. Experimental neurology. vol 264. 2015-03-30. PMID:25476494. |
adult neurogenesis, the generation of new neurons in the adult brain, occurs in the hippocampal dentate gyrus (dg) and the olfactory bulb (ob) of all mammals, but the functions of these new neurons are not entirely clear. |
2015-03-30 |
2023-08-13 |
mouse |
| R Kohen, A Dobra, J H Tracy, E Hauge. Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness. Translational psychiatry. vol 4. 2015-03-06. PMID:24594777. |
we investigated the transcriptome of dentate gyrus (dg) granule cells in postmortem human hippocampus in 79 subjects with mental illness (schizophrenia, bipolar disorder, major depression) and nonpsychiatric controls. |
2015-03-06 |
2023-08-12 |
human |
| Quan-Guang Zhang, Ruimin Wang, Hui Tang, Yan Dong, Alice Chan, Gangadhara Reddy Sareddy, Ratna K Vadlamudi, Darrell W Bran. Brain-derived estrogen exerts anti-inflammatory and neuroprotective actions in the rat hippocampus. Molecular and cellular endocrinology. vol 389. issue 1-2. 2015-03-02. PMID:24508637. |
immunohistochemistry (ihc) revealed that the hippocampal regions ca1, ca3 and dentate gyrus (dg) exhibited high levels of immunoreactive aromatase staining, with aromatase being co-localized primarily in neurons in non-ischemic animals. |
2015-03-02 |
2023-08-12 |
rat |
| Jianlong Zhuang, Qiulan Wei, Zhaohua Lin, Changwen Zho. Effects of ADAM10 deletion on Notch-1 signaling pathway and neuronal maintenance in adult mouse brain. Gene. vol 555. issue 2. 2015-02-17. PMID:25445276. |
we found that conditional disruption of adam10 resulted in a prominent decrease in the number of proliferating neuronal progenitor cells in the subgranular zone (sgz), and a significant increase in the number of adult-generated postmitotic neurons in the hippocampal dentate gyrus (dg) due to premature neuronal differentiation. |
2015-02-17 |
2023-08-13 |
mouse |
| Jianlong Zhuang, Qiulan Wei, Zhaohua Lin, Changwen Zho. Effects of ADAM10 deletion on Notch-1 signaling pathway and neuronal maintenance in adult mouse brain. Gene. vol 555. issue 2. 2015-02-17. PMID:25445276. |
moreover, the mutant mice also displayed an age-dependent reduction in the number of granule neurons in the hippocampal dg. |
2015-02-17 |
2023-08-13 |
mouse |
| Dustin R Masser, Georgina V Bixler, Robert M Brucklacher, Han Yan, Cory B Giles, Jonathan D Wren, William E Sonntag, Willard M Freema. Hippocampal subregions exhibit both distinct and shared transcriptomic responses to aging and nonneurodegenerative cognitive decline. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 69. issue 11. 2015-02-13. PMID:24994846. |
hippocampal subregions (ca1, ca3, and dg) have been previously reported to express both common and specific morphological, functional, and gene/protein alterations with aging and cognitive decline. |
2015-02-13 |
2023-08-13 |
rat |
| Melody V Wu, Jul Lea Shamy, Gillinder Bedi, Chien-Wen J Choi, Melanie M Wall, Victoria Arango, Maura Boldrini, Richard W Foltin, René He. Impact of social status and antidepressant treatment on neurogenesis in the baboon hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 8. 2015-02-12. PMID:24518288. |
to better bridge the gap between rodent and human physiology, we examined the numbers of proliferating neural precursors and immature cells in the hippocampal dentate gyrus (dg) as well as in vivo magnetic resonance imaging (mri)-estimated whole hippocampal volume in eight socially dominant- or subordinate-like (sl) baboons administered the antidepressant fluoxetine or vehicle. |
2015-02-12 |
2023-08-12 |
human |
| Melody V Wu, Jul Lea Shamy, Gillinder Bedi, Chien-Wen J Choi, Melanie M Wall, Victoria Arango, Maura Boldrini, Richard W Foltin, René He. Impact of social status and antidepressant treatment on neurogenesis in the baboon hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 8. 2015-02-12. PMID:24518288. |
these findings are the first to indicate that adult neurogenesis in the baboon hippocampal dg may be functionally relevant in the context of social stress and mechanisms of antidepressant action. |
2015-02-12 |
2023-08-12 |
human |
| Laura E M Wisse, Geert Jan Biessels, Sophie M Heringa, Hugo J Kuijf, Dineke H L Koek, Peter R Luijten, Mirjam I Geerling. Hippocampal subfield volumes at 7T in early Alzheimer's disease and normal aging. Neurobiology of aging. vol 35. issue 9. 2015-02-12. PMID:24684788. |
erc, subiculum, cornu ammonis (ca)1, ca2, ca3, and dentate gyrus (dg)&ca4 were traced on t2-weighted images. |
2015-02-12 |
2023-08-12 |
Not clear |
| V N Marty, R Vlkolinsky, N Minassian, T Cohen, G A Nelson, I Spigelma. Radiation-induced alterations in synaptic neurotransmission of dentate granule cells depend on the dose and species of charged particles. Radiation research. vol 182. issue 6. 2015-02-12. PMID:25402556. |
the purpose of this study was to evaluate and compare the effects of low-dose proton and high-energy charged particle (hze) radiation on electrophysiological parameters of the granule cells in the dentate gyrus (dg) of the hippocampus and its associated functional consequences. |
2015-02-12 |
2023-08-13 |
mouse |
| Athanasios Stergiopoulos, Maximilianos Elkouris, Panagiotis K Politi. Prospero-related homeobox 1 (Prox1) at the crossroads of diverse pathways during adult neural fate specification. Frontiers in cellular neuroscience. vol 8. 2015-02-12. PMID:25674048. |
recent evidence indicates that the homeobox transcription factor prox1 is a critical intrinsic regulator of neurogenesis in the embryonic cns and adult dentate gyrus (dg) of the hippocampus, acting in multiple ways and instructed by extrinsic cues and intrinsic factors. |
2015-02-12 |
2023-08-13 |
Not clear |
| Athanasios Stergiopoulos, Maximilianos Elkouris, Panagiotis K Politi. Prospero-related homeobox 1 (Prox1) at the crossroads of diverse pathways during adult neural fate specification. Frontiers in cellular neuroscience. vol 8. 2015-02-12. PMID:25674048. |
during the complex differentiation events in adult hippocampal neurogenesis, prox1 is required for maintenance of intermediate progenitors (ips), differentiation and maturation of glutamatergic interneurons, as well as specification of dg cell identity over ca3 pyramidal fate. |
2015-02-12 |
2023-08-13 |
Not clear |
| MingXin Fa, Li Xia, Rachel Anunu, Orli Kehat, Martin Kriebel, Hansjürgen Volkmer, Gal Richter-Levi. Stress modulation of hippocampal activity--spotlight on the dentate gyrus. Neurobiology of learning and memory. vol 112. 2015-02-09. PMID:24747273. |
in the current review, we summarize work which suggests that the dentate gyrus (dg) of the hippocampus is likely to play a pivotal role in defining the impact of stress on hippocampal functioning. |
2015-02-09 |
2023-08-13 |
Not clear |
| J Gil-Mohapel, A K Titterness, A R Patten, S Taylor, A Ratzlaff, T Ratzlaff, J Helfer, B R Christi. Prenatal ethanol exposure differentially affects hippocampal neurogenesis in the adolescent and aged brain. Neuroscience. vol 273. 2015-02-09. PMID:24846617. |
the hippocampus is composed of two interlocking gyri, the cornu ammonis (ca) and the dentate gyrus (dg), and they are differentially affected by prenatal ethanol exposure. |
2015-02-09 |
2023-08-13 |
Not clear |
| María Llorens-Martín, Jerónimo Jurado-Arjona, Jesús Avila, Félix Hernánde. Novel connection between newborn granule neurons and the hippocampal CA2 field. Experimental neurology. vol 263. 2015-02-09. PMID:25446721. |
newborn neurons are continuously added to the hippocampal dentate gyrus (dg) throughout life. |
2015-02-09 |
2023-08-13 |
Not clear |
| Hui-Di Yang, Qian Wang, De-Hua Wan. Food hoarding, but not food intake, is attenuated by acute diazepam treatment in female Mongolian gerbils (Meriones unguiculatus). Hormones and behavior. vol 66. issue 1. 2015-02-07. PMID:24681217. |
moreover, diazepam increased fos expression in field ca2 and ca3 of the hippocampus, but had no significant effect on fos expression in field ca1 and dentate gyrus (dg) of the hippocampus, indicating that the hippocampus has area-specific effects on food hoarding in hfh gerbils. |
2015-02-07 |
2023-08-12 |
Not clear |