All Relations between nlrp3 and matrix compartment
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| Wenjie Wang, Xiangyu Wang, Justin Chun, Akosua Vilaysane, Sharon Clark, Gabrielle French, Nathan A Bracey, Kiril Trpkov, Shirin Bonni, Henry J Duff, Paul L Beck, Daniel A Muruv. Inflammasome-independent NLRP3 augments TGF-β signaling in kidney epithelium. Journal of immunology (Baltimore, Md. : 1950). vol 190. issue 3. 2013-03-26. PMID:23264657. | in human and mouse primary renal tecs, nlrp3 expression was increased in response to tgf-β1 stimulation and associated with epithelial-mesenchymal transition (emt) and the expression of α-smooth muscle actin (αsma) and matrix metalloproteinase (mmp) 9. | 2013-03-26 | 2023-08-12 | mouse |
| Robert Zeiser, Olaf Penack, Ernst Holler, Marco Idzk. Danger signals activating innate immunity in graft-versus-host disease. Journal of molecular medicine (Berlin, Germany). vol 89. issue 9. 2011-12-08. PMID:21573893. | besides atp, uric acid or soluble extracellular matrix components are functional danger signals that activate the nlrp3 inflammasome when released from dying cells or from extracellular matrix. | 2011-12-08 | 2023-08-12 | Not clear |
| Andrea Babelova, Kristin Moreth, Wasiliki Tsalastra-Greul, Jinyang Zeng-Brouwers, Oliver Eickelberg, Marian F Young, Peter Bruckner, Josef Pfeilschifter, Roland M Schaefer, Hermann-Josef Gröne, Liliana Schaefe. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. The Journal of biological chemistry. vol 284. issue 36. 2009-10-05. PMID:19605353. | our results provide evidence for direct activation of the nlrp3 inflammasome by biglycan and describe a fundamental paradigm of how tissue stress or injury is monitored by innate immune receptors detecting the release of the extracellular matrix components and turning such a signal into a robust inflammatory response. | 2009-10-05 | 2023-08-12 | mouse |