| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joel G Hashimoto, Nicholas Margolies, Xiaolu Zhang, Joshua Karpf, Yuefan Song, Brett A Davis, Fuming Zhang, Robert J Linhardt, Lucia Carbone, Marina Guizzett. Astrocyte extracellular matrix modulates neuronal dendritic development. bioRxiv : the preprint server for biology. 2024-08-30. PMID:39211148. |
major developmental events occurring in the hippocampus during the third trimester of human gestation and neonatally in altricial rodents include rapid and synchronized dendritic arborization and astrocyte proliferation and maturation. |
2024-08-30 |
2024-09-04 |
mouse |
| Nosarieme Omoregie Abey, Osaretin Albert Taiwo Ebuehi, Ngozi Awa Imag. Effect of perinatal dietary protein deficiency on some neurochemicals and cytoarchitectural balance, in F1 and F2 generations of rats. Nutritional neuroscience. vol 27. issue 9. 2024-08-27. PMID:37995096. |
gfap astrocyte expression was observed to be increased in the prefrontal cortex (pfc) and hippocampal sections, indicating heightened reactivity. |
2024-08-27 |
2024-08-30 |
rat |
| Brenda Lizeth Gutiérrez-Esparza, Marina Liliana González-Torres, Andrés Quintanar-Stephano, J Luis Quintana. Neurological recovery in rats with portocaval anastomosis-induced hepatic encephalopathy treated with leuprolide acetate, a GnRH agonist. Metabolic brain disease. 2024-08-23. PMID:39177865. |
in this study, we aim to evaluate the effects of la treatment on hippocampus of rats with he induced by portocaval anastomosis (pca) trough cognitive tests, histology analysis and expression of neuronal recovery marker proteins, such as neurofilament (nf200) and neurabin ii, and astrocyte marker glial fibrillary acidic protein (gfap). |
2024-08-23 |
2024-08-25 |
rat |
| Paras S Minhas, Jeffrey R Jones, Amira Latif-Hernandez, Yuki Sugiura, Aarooran S Durairaj, Qian Wang, Siddhita D Mhatre, Takeshi Uenaka, Joshua Crapser, Travis Conley, Hannah Ennerfelt, Yoo Jin Jung, Ling Liu, Praveena Prasad, Brenita C Jenkins, Yeonglong Albert Ay, Matthew Matrongolo, Ryan Goodman, Traci Newmeyer, Kelly Heard, Austin Kang, Edward N Wilson, Tao Yang, Erik M Ullian, Geidy E Serrano, Thomas G Beach, Marius Wernig, Joshua D Rabinowitz, Makoto Suematsu, Frank M Longo, Melanie R McReynolds, Fred H Gage, Katrin I Andreasso. Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies. Science (New York, N.Y.). vol 385. issue 6711. 2024-08-22. PMID:39172838. |
we report that inhibition of indoleamine-2,3-dioxygenase 1 (ido1), which metabolizes tryptophan to kynurenine (kyn), rescues hippocampal memory function in mouse preclinical models of ad by restoring astrocyte metabolism. |
2024-08-22 |
2024-08-25 |
mouse |
| Masoud Kaboutari, Masoumeh Asle-Rousta, Sanaz Mahmaz. Protective effect of menthol against thioacetamide-induced hepatic encephalopathy by suppressing oxidative stress and inflammation, augmenting expression of BDNF and α7-nACh receptor, and improving spatial memory. European journal of pharmacology. 2024-08-18. PMID:39154831. |
menthol also reduced neuronal death in the hippocampal cornu ammonis-1 and dentate gyrus regions and reduced astrocyte swelling, which led to improved learning and spatial memory in rats with he. |
2024-08-18 |
2024-08-21 |
rat |
| Na Hu, Yujie Zheng, Xueru Liu, Jing Jia, Jianguo Feng, Chunxiang Zhang, Li Liu, Xiaobin Wan. CircKat6b Mediates the Antidepressant Effect of Esketamine by Regulating Astrocyte Function. Molecular neurobiology. 2024-08-14. PMID:39138759. |
our findings demonstrated that a novel mechanism of the antidepressant like effect of esketamine may be achieved by reducing the expression of circkat6b in the astrocyte of the hippocampus of depressed mice. |
2024-08-14 |
2024-08-16 |
mouse |
| Andrew Pearson, Milica Koprivica, Max Eisenbaum, Camila Ortiz, Mackenzie Browning, Tessa Vincennie, Cooper Tinsley, Michael Mullan, Fiona Crawford, Joseph Oj. PPARγ activation ameliorates cognitive impairment and chronic microglial activation in the aftermath of r-mTBI. Journal of neuroinflammation. vol 21. issue 1. 2024-08-03. PMID:39097742. |
we revealed that pioglitazone treatment attenuated spatial learning and memory impairments at 6 months post-injury and reduced the expression of reactive microglia and astrocyte markers in the cortex, hippocampus, and corpus callosum. |
2024-08-03 |
2024-08-06 |
mouse |
| Iardja S L Sales, Alana G de Souza, Adriano J M Chaves Filho, Tiago L Sampaio, Daniel M A da Silva, José T Valentim, Raquell de C Chaves, Michelle V R Soares, Dilailson C Costa Júnior, José M Barbosa Filho, Danielle S Macêdo, Francisca Cléa Florenço de Sous. Antidepressant-like effect of riparin I and riparin II against CUMS-induced neuroinflammation via astrocytes and microglia modulation in mice. Behavioural pharmacology. vol 35. issue 6. 2024-08-02. PMID:39094014. |
expressions of microglia (ionized calcium-binding adaptor molecule-1 - iba-1) and astrocyte (glial fibrillary acidic protein - gfap) markers and levels of cytokines tumor necrosis factor alfa (tnf-α) and interleukin 1 beta (il-1β) were measured in the hippocampus. |
2024-08-02 |
2024-08-06 |
mouse |
| AnnaLin M Woo, Harald Sontheime. Interactions between astrocytes and extracellular matrix structures contribute to neuroinflammation-associated epilepsy pathology. Frontiers in molecular medicine. vol 3. 2024-08-01. PMID:39086689. |
we offer epilepsy as a well-studied neurological disorder in which there is clear evidence of astrocyte contribution to diseases as evidenced across several different disease models, including mouse models of hippocampal sclerosis, trauma associated epilepsy, glioma-associated epilepsy, and beta-1 integrin knockout astrogliosis. |
2024-08-01 |
2024-08-03 |
mouse |
| Derek W Nelson, Jessica L Funnell, Conrad H Cheung, Geraldine B Quinones, Christina S Mendoza, Marvin Bentley, Ryan J Gilber. In vitro assessment of protamine toxicity with neural cells, its therapeutic potential to counter chondroitin sulfate mediated neuron inhibition, and its effects on reactive astrocytes. Advanced therapeutics. vol 7. issue 2. 2024-07-29. PMID:39071184. |
in this study, we investigate the therapeutic efficacy of prm with primary cortical neurons, hippocampal neurons, mixed glial cultures, and astrocyte cultures. |
2024-07-29 |
2024-08-02 |
Not clear |
| Opeyemi Babatunde Ogunsuyi, Omodesola Oluwafisayo Ogunruku, Haruna Isiyaku Umar, Ganiyu Obo. Effect of curcumin-donepezil combination on spatial memory, astrocyte activation, and cholinesterase expressions in brain of scopolamine-treated rats. Molecular biology reports. vol 51. issue 1. 2024-07-29. PMID:39073463. |
the study investigated the effect of co-administration of curcumin and donepezil on several markers of cognitive function (such as spatial memory, astrocyte activation, cholinesterase expressions) in the brain cortex and hippocampus of scopolamine-treated rats. |
2024-07-29 |
2024-08-02 |
rat |
| Katharina Ritter, Markus Baalmann, Christopher Dolderer, Ulrike Ritz, Michael K E Schäfe. Brain-Bone Crosstalk in a Murine Polytrauma Model Promotes Bone Remodeling but Impairs Neuromotor Recovery and Anxiety-Related Behavior. Biomedicines. vol 12. issue 7. 2024-07-27. PMID:39061973. |
bone fractures did not aggravate neuropathology or neuroinflammation assessed by cerebral lesion size, hippocampal integrity, astrocyte and microglia activation, and gene expression. |
2024-07-27 |
2024-07-29 |
mouse |
| b' Nata\\xc5\\xa1a Mitrovi\\xc4\\x87, Marija Ad\\xc5\\xbei\\xc4\\x87 Bukvi\\xc4\\x87, Marina Zari\\xc4\\x87 Konti\\xc4\\x87, Milorad Dragi\\xc4\\x87, Snje\\xc5\\xbeana Petrovi\\xc4\\x87, Marija Paunovi\\xc4\\x87, Vesna Vu\\xc4\\x8di\\xc4\\x87, Ivana Grkovi\\xc4\\x8. Flaxseed Oil Alleviates Trimethyltin-Induced Cell Injury and Inhibits the Pro-Inflammatory Activation of Astrocytes in the Hippocampus of Female Rats. Cells. vol 13. issue 14. 2024-07-26. PMID:39056766.' |
exposure to the neurotoxin trimethyltin (tmt) selectively induces hippocampal neuronal injury and astrocyte activation accompanied with resultant neuroinflammation, which causes severe behavioral, cognitive, and memory impairment. |
2024-07-26 |
2024-07-28 |
rat |
| Iardja S L Sales, Alana G de Souza, Adriano J M Chaves Filho, Tiago L Sampaio, Daniel M A da Silva, José T Valentim, Raquell de C Chaves, Michelle V R Soares, Dilailson C Costa Júnior, José M Barbosa Filho, Danielle S Macêdo, Francisca Cléa Florenço de Sous. Antidepressant-like effect of riparin I and riparin II against CUMS-induced neuroinflammation via astrocytes and microglia modulation in mice. Behavioural pharmacology. 2024-07-25. PMID:39051915. |
expressions of microglia (ionized calcium-binding adaptor molecule-1 - iba-1) and astrocyte (glial fibrillary acidic protein - gfap) markers and levels of cytokines tumor necrosis factor alfa (tnf-α) and interleukin 1 beta (il-1β) were measured in the hippocampus. |
2024-07-25 |
2024-07-28 |
mouse |
| Dabing Li, Qiangwen Pan, Yewei Xiao, Kehui H. Advances in the study of phencyclidine-induced schizophrenia-like animal models and the underlying neural mechanisms. Schizophrenia (Heidelberg, Germany). vol 10. issue 1. 2024-07-22. PMID:39039065. |
in addition, astrocyte and microglial activation and oxidative stress in the cerebral cortex or hippocampus have been observed in pcp-induced models of sz. |
2024-07-22 |
2024-07-25 |
Not clear |
| Cheng-Fu Li, Qiu-Ping Zhang, Jie Cheng, Guang-Hui Xu, Ji-Xiao Zhu, Li-Tao Y. Role of ginsenoside Rb1 in attenuating depression-like symptoms through astrocytic and microglial complement C3 pathway. Metabolic brain disease. 2024-07-21. PMID:39034364. |
in conclusion, our results demonstrate that ginsenoside rb1 produces the antidepressant-like effects by inhibiting astrocyte tlr4/nf-κb/c3 signaling to covert microglia from a pro-inflammatory phenotype (amoeboid) towards an anti-inflammatory phenotype (ramified), which inhibit the synaptic pruning in the hippocampus. |
2024-07-21 |
2024-07-24 |
mouse |
| Priya Tiwari, Sumbul Mueed, Adam Olaitan Abdulkareem, Kashif Hani. Activation of angiotensin-converting enzyme 2 promotes hippocampal neurogenesis via activation of Wnt/β-catenin signaling in hypertension. Molecular and cellular neurosciences. 2024-07-16. PMID:39013481. |
the results of our study revealed that hypertension induced significant glial activation (astrocyte and microglial), neuroinflammation, and impaired hippocampal neurogenesis. |
2024-07-16 |
2024-07-19 |
rat |
| Charlotte Lorin, Romain Guiet, Nicolas Chiaruttini, Giovanna Ambrosini, Elvis Boci, Marwan Abdellah, Henry Markram, Daniel Kelle. Structural and molecular characterization of astrocyte and vasculature connectivity in the mouse hippocampus and cortex. Glia. 2024-07-15. PMID:39007459. |
structural and molecular characterization of astrocyte and vasculature connectivity in the mouse hippocampus and cortex. |
2024-07-15 |
2024-07-18 |
mouse |
| Jae-Hong Kim, Nakamura Michiko, In-Sun Choi, Yujung Kim, Ji-Young Jeong, Maan-Gee Lee, Il-Sung Jang, Kyoungho Su. Aberrant activation of hippocampal astrocytes causes neuroinflammation and cognitive decline in mice. PLoS biology. vol 22. issue 7. 2024-07-11. PMID:38991663. |
fiber photometry using gcamp revealed a high level of hippocampal astrocyte activation in the neuroinflammation model. |
2024-07-11 |
2024-07-14 |
mouse |
| Sin Ho Kweon, Hye Guk Ryu, Seung-Hwan Kwon, Hyeonwoo Park, Saebom Lee, Nam-Shik Kim, Shi-Xun Ma, Hee-Jung Jee, Sangjune Kim, Han Seok K. Gba1 E326K renders motor and non-motor symptoms with pathologic α-syn, tau and glial activation. Brain : a journal of neurology. 2024-07-08. PMID:38976650. |
gut inoculation of α-syn pff increased lewy body accumulation in the hippocampal dentate gyrus, with heightened microglia and astrocyte activation and worsened non-motor symptoms. |
2024-07-08 |
2024-07-12 |
mouse |