| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhenguo Pan, Xiaoyu Yu, Weiwei Wang, Kai Shen, Jianwei Chen, Yunfeng Zhang, Rongrong Huan. Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy. Journal of neurochemistry. 2024-05-18. PMID:38761015. |
in this study, we reported that sestrin2 and autophagy were significantly induced in mouse hippocampus after multiple intraperitoneal injections of lipopolysaccharide, with the elevation of a1 astrocyte conversion and inflammatory mediators. |
2024-05-18 |
2024-05-27 |
mouse |
| b' Macarena Lorena Herrera, Leandro Gabriel Champarini, Osvaldo Mart\\xc3\\xadn Basmadjian, Mar\\xc3\\xada Jos\\xc3\\xa9 Bellini, Claudia Beatriz Here\\xc3\\xb1\\xc3\\xb. IGF-1 gene therapy prevents spatial memory deficits and modulates dopaminergic neurodegeneration and inflammation in a parkinsonism model. Brain, behavior, and immunity. vol 119. 2024-05-17. PMID:38750702.' |
in addition, the therapy resulted in significant changes in several parameters (area, perimeter, roundness, ramification, and skeleton ́s analyses) related to microglia and astrocyte phenotypes, particularly in the cpu and dorsal hippocampal areas. |
2024-05-17 |
2024-05-27 |
rat |
| Ziqing Zhou, Jing Li, Xiaoke Wang, Yue Si, Xudong Zhu, Yingfeng Lei, Hongwei Ma, Fanglin Zhan. [Changes and intervention of reactive astrocyte activation patterns in the progression of Japanese encephalitis]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 40. issue 4. 2024-05-06. PMID:38710514. |
conclusion neurons in the m1/m2 motor cortex and hippocampus are susceptible to jev infection, in which the abnormal astrocyte activation contributes to the neuroinflammatory injury. |
2024-05-06 |
2024-05-27 |
mouse |
| Danijela Bataveljic, Helena Pivonkova, Vidian de Concini, Betty Hébert, Pascal Ezan, Sylvain Briault, Alexis-Pierre Bemelmans, Jacques Pichon, Arnaud Menuet, Nathalie Rouac. Astroglial Kir4.1 potassium channel deficit drives neuronal hyperexcitability and behavioral defects in Fragile X syndrome mouse model. Nature communications. vol 15. issue 1. 2024-04-28. PMID:38678030. |
viral delivery of kir4.1 channels specifically to hippocampal astrocytes from fmr1 knockout mice indeed rescues normal astrocyte potassium uptake, neuronal excitability, and cognitive and social performance. |
2024-04-28 |
2024-04-30 |
mouse |
| Mengya Jiao, Chenchen Wang, Xuhuan Tang, Chan Dai, Na Zhang, Anqi Fan, Zhigang Qian, Shiwang Liu, Feng Zhang, Bin Li, Yong Xu, Zheng Tan, Feili Gong, Yisheng Lu, Fang Zhen. Active secretion of IL-33 from astrocytes is dependent on TMED10 and promotes central nervous system homeostasis. Brain, behavior, and immunity. 2024-04-25. PMID:38663774. |
knockout of il-33 or its receptor st2 induced hippocampal astrocyte activation and depressive-like disorder in naive mice, as well as increased spinal cord astrocyte activation and polarization to a neurotoxic reactive subtype and aggravated passive experimental autoimmune encephalomyelitis (eae). |
2024-04-25 |
2024-04-28 |
mouse |
| Luis A Rojas-Colón, John B Redell, Pramod K Dash, Pedro E Vegas, Wanda Vélez-Torre. 4R-cembranoid suppresses glial cells inflammatory phenotypes and prevents hippocampal neuronal loss in LPS-treated mice. Journal of neuroscience research. vol 102. issue 4. 2024-04-24. PMID:38656664. |
confocal images of brain sections immunostained for microglial, astrocyte, and neuronal markers were used to quantify cellular hippocampal phenotypes and neurons. |
2024-04-24 |
2024-04-28 |
mouse |
| Ji-Yong Liu, Wen-Li Zhang, Jun Liao, Li-Juan Hu, Guo-Zuo Wang, Jin-Wen Ge, Zhi-Gang Me. [Effect of Naotaifang on microglial polarization and glial scar following cerebral ischemia reperfusion injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 4. 2024-04-15. PMID:38621906. |
compared with the sham, model 7 d and model 14 d groups showed cerebral infarction of different degrees, severe pathological injury of cerebral cortex and hippocampus, neurological impairment, reduced spatial learning and memory, cognitive dysfunction, severe anxiety, astrocyte hyperplasia, thickening penumbra glial scar, and up-regulated protein levels of il-1β, il-6, gfap, neurocan, phosphacan, cd206, and arg-1(p<0.01). |
2024-04-15 |
2024-04-18 |
rat |
| Yue Li, Yanmin Luo, Peilin Zhu, Xin Liang, Jing Li, Xiaoyun Dou, Li Liu, Lu Qin, Mei Zhou, Yuhui Deng, Lin Jiang, Shun Wang, Wenyu Yang, Jing Tang, Yong Tan. Running exercise improves astrocyte loss, morphological complexity and astrocyte-contacted synapses in the hippocampus of CUS-induced depression model mice. Pharmacology, biochemistry, and behavior. 2024-03-17. PMID:38494007. |
running exercise improves astrocyte loss, morphological complexity and astrocyte-contacted synapses in the hippocampus of cus-induced depression model mice. |
2024-03-17 |
2024-03-20 |
mouse |
| Yue Li, Yanmin Luo, Peilin Zhu, Xin Liang, Jing Li, Xiaoyun Dou, Li Liu, Lu Qin, Mei Zhou, Yuhui Deng, Lin Jiang, Shun Wang, Wenyu Yang, Jing Tang, Yong Tan. Running exercise improves astrocyte loss, morphological complexity and astrocyte-contacted synapses in the hippocampus of CUS-induced depression model mice. Pharmacology, biochemistry, and behavior. 2024-03-17. PMID:38494007. |
astrocyte processes physically contact many synapses and directly regulate the numbers of synapses, but it remains unclear whether running exercise can modulate astrocyte morphological complexity and astrocyte-contacted synapses in the hippocampus of the mice with depressive-like behavior. |
2024-03-17 |
2024-03-20 |
mouse |
| Yue Li, Yanmin Luo, Peilin Zhu, Xin Liang, Jing Li, Xiaoyun Dou, Li Liu, Lu Qin, Mei Zhou, Yuhui Deng, Lin Jiang, Shun Wang, Wenyu Yang, Jing Tang, Yong Tan. Running exercise improves astrocyte loss, morphological complexity and astrocyte-contacted synapses in the hippocampus of CUS-induced depression model mice. Pharmacology, biochemistry, and behavior. 2024-03-17. PMID:38494007. |
the expression of astrocyte- and synapse-related proteins in the hippocampus; astrocyte process lengths, process numbers, and dendritic arborization; and the number of astrocyte-contacted psd95 positive synapses in the ca2-3 and dg regions were significantly decreased in the mice with depressive-like behavior, and running exercise successfully reserved these changes. |
2024-03-17 |
2024-03-20 |
mouse |
| Ana Laura Reyes-Ábalos, Magdalena Álvarez-Zabaleta, Silvia Olivera-Bravo, María Vittoria Di Tomas. Acute Genetic Damage Induced by Ethanol and Corticosterone Seems to Modulate Hippocampal Astrocyte Signaling. International journal of cell biology. vol 2024. 2024-03-05. PMID:38439918. |
acute genetic damage induced by ethanol and corticosterone seems to modulate hippocampal astrocyte signaling. |
2024-03-05 |
2024-03-07 |
Not clear |
| Jing Zhu, Soojin Park, Se Hoon Kim, Chul Hoon Kim, Kyoung Hoon Jeong, Won-Joo Ki. Sirtuin 3 regulates astrocyte activation by reducing Notch1 signaling after status epilepticus. Glia. 2024-02-26. PMID:38406970. |
the upregulation of sirt3 by treatment with adjudin, a potential sirt3 activator, alleviated se-induced astrocyte activation; whereas, sirt3 deficiency exacerbated astrocyte activation in the hippocampus after se. |
2024-02-26 |
2024-02-28 |
mouse |
| Jiawei Yang, Ying Wang, Yuyan Xia, Yajie Ren, Zhi Wang, Xin Meng, Shuangyue Li, Xiaohui Liu, Jing Sha. PFOS Elicits Cytotoxicity in Neuron Through Astrocyte-Derived CaMKII-DLG1 Signaling In Vitro Rat Hippocampal Model. Neurochemical research. 2024-02-23. PMID:38393622. |
in the present study, the role of astrocyte-derived calmodulin-dependent protein kinase ii (camkii)-phosphorylated discs large homolog 1 (dlg1) signaling in pfos eliciting cytotoxicity in neuron was explored with primary cultured hippocampal astrocyte and neuron. |
2024-02-23 |
2024-02-25 |
rat |
| Hyun Seung Shin, Seung Hyun Lee, Ha Jung Moon, Yun Hee So, Hyeon Jung Jang, Kyung-Ha Lee, Changhwan Ahn, Eui-Man Jun. Prolonged stress response induced by chronic stress and corticosterone exposure causes adult neurogenesis inhibition and astrocyte loss in mouse hippocampus. Brain research bulletin. 2024-02-17. PMID:38367676. |
prolonged stress response induced by chronic stress and corticosterone exposure causes adult neurogenesis inhibition and astrocyte loss in mouse hippocampus. |
2024-02-17 |
2024-02-20 |
mouse |
| Bin Mei, Xiaoxia Xu, Juntao Weng, Yueyue Yang, Peng Wang, Gaolin Qiu, Chi Zhang, Qunlin Zhang, Yao Lu, Xuesheng Li. Activating astrocytic α2A adrenoceptors in hippocampus reduces glutamate toxicity to attenuate sepsis-associated encephalopathy in mice. Brain, behavior, and immunity. 2024-02-06. PMID:38320682. |
this study was performed to determine whether hippocampal astrocytic α2a-ar activation confers neuroprotection against sae and whether this protective effect is astrocyte specific and achieved by the modulation of glutamate metabolism. |
2024-02-06 |
2024-02-09 |
mouse |
| Nicholas Guerini Selistre, Leticia Rodrigues, Barbara Carolina Federhen, Vitor Gayger-Dias, Jéssica Taday, Krista Mineia Wartchow, Carlos-Alberto Gonçalve. S100B Secretion in Astrocytes, Unlike C6 Glioma Cells, Is Downregulated by Lactate. Metabolites. vol 14. issue 1. 2024-01-26. PMID:38276297. |
herein, we investigate the impact of fc on s100b secretion in primary astrocyte cultures, acute hippocampal slices and c6 glioma cells, as well as lactate mediation. |
2024-01-26 |
2024-01-28 |
Not clear |
| Shiva Zeini, Nahid Davoodian, Seyed Abdollah Mousav. Gamma-oryzanol attenuates lipopolysaccharide-induced cognitive impairment by modulation of hippocampal inflammatory response and glial activation in mice. Journal of neuroimmunology. vol 387. 2024-01-26. PMID:38278081. |
also, neuronal loss, microglia, and astrocyte densities were evaluated in the ca1 and ca3 hippocampus. |
2024-01-26 |
2024-01-29 |
mouse |
| Wookbong Kwon, Dong-Joo Choi, Kwanha Yu, Michael R Williamson, Sanjana Murali, Yeunjung Ko, Junsung Woo, Benjamin Denee. Comparative Transcriptomic Analysis of Cerebellar Astrocytes across Developmental Stages and Brain Regions. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38256095. |
comparing these profiles with region-specific astrocyte differentially expressed genes (degs) published for the cortex, hippocampus, and olfactory bulb revealed cerebellar-specific gene signature across these developmental timepoints. |
2024-01-23 |
2024-01-25 |
Not clear |
| Qian Li, Wei Zhang, Xin-Yu Qiao, Chong Liu, Ji-Ji Dao, Chen-Meng Qiao, Chun Cui, Yan-Qin Shen, Wei-Jiang Zha. Reducing polypyrimidine tract‑binding protein 1 fails to promote neuronal transdifferentiation on HT22 and mouse astrocyte cells under physiological conditions. Experimental and therapeutic medicine. vol 27. issue 2. 2024-01-18. PMID:38234625. |
therefore, the present study explored the effect of knocking down ptbp1 under physiological conditions on the transdifferentiation of mouse hippocampal neuron ht22 cells and mouse astrocyte (ma) cells. |
2024-01-18 |
2024-01-20 |
mouse |
| Stefanie Anders, Björn Breithausen, Petr Unichenko, Michel K Herde, Daniel Minge, Adlin Abramian, Charlotte Behringer, Tushar Deshpande, Anne Boehlen, Cátia Domingos, Lukas Henning, Julika Pitsch, Young-Bum Kim, Peter Bedner, Christian Steinhäuser, Christian Henneberge. Epileptic activity triggers rapid ROCK1-dependent astrocyte morphology changes. Glia. vol 72. issue 3. 2024-01-13. PMID:38031824. |
we uncovered astrocyte morphology changes within 10-20 min under various experimental conditions in acute hippocampal slices. |
2024-01-13 |
2024-01-15 |
Not clear |