| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Mena, U Khan, D M Togasaki, D Sulzer, C J Epstein, S Przedborsk. Effects of wild-type and mutated copper/zinc superoxide dismutase on neuronal survival and L-DOPA-induced toxicity in postnatal midbrain culture. Journal of neurochemistry. vol 69. issue 1. 1997-07-24. PMID:9202290. |
as the spontaneous loss and l-dopa-induced loss of postnatal dopaminergic midbrain neurons appear to be mediated by free radicals, our study supports the view that mutated cu/zn-sod enzyme kills cells by oxidative stress. |
1997-07-24 |
2023-08-12 |
mouse |
| M Manier, N Cristina, C Chatellard-Causse, P Mouchet, J P Herman, C Feuerstei. Striatal target-induced axonal branching of dopaminergic mesencephalic neurons in culture via diffusible factors. Journal of neuroscience research. vol 48. issue 4. 1997-07-21. PMID:9169862. |
the effects of striatal target cells on the morphological development of dopaminergic neurons were studied in dissociated cultures of embryonic rat mesencephalon. |
1997-07-21 |
2023-08-12 |
rat |
| G Dziewczapolski, G Murer, Y Agid, O Gershanik, R Raisman-Vozar. Absence of neurotoxicity of chronic L-DOPA in 6-hydroxydopamine-lesioned rats. Neuroreport. vol 8. issue 4. 1997-07-14. PMID:9141075. |
this suggest that in vivo, this treatment is not toxic either to healthy dopaminergic neurones of the ventral mesencephalon or to those surviving after a 6-ohda lesion. |
1997-07-14 |
2023-08-12 |
rat |
| G J Molenaar, R I Hogenesch, M E Sprengers, M J Staa. Ontogenesis of embryonic porcine ventral mesencephalon in the perspective of its potential use as a xenograft in Parkinson's disease. The Journal of comparative neurology. vol 382. issue 1. 1997-07-07. PMID:9136809. |
we conclude that the ventral mesencephalon in pig embryos of 28 days is a potential source of dopaminergic neurons to be used as a xenograft in pd. |
1997-07-07 |
2023-08-12 |
human |
| G Mereu, V Lilliu, A Casula, P F Vargiu, M Diana, A Musa, G L Gess. Spontaneous bursting activity of dopaminergic neurons in midbrain slices from immature rats: role of N-methyl-D-aspartate receptors. Neuroscience. vol 77. issue 4. 1997-07-01. PMID:9130784. |
spontaneous bursting activity of dopaminergic neurons in midbrain slices from immature rats: role of n-methyl-d-aspartate receptors. |
1997-07-01 |
2023-08-12 |
rat |
| H I Kornblum, R J Hussain, J M Bronstein, C M Gall, D C Lee, K B Seroog. Prenatal ontogeny of the epidermal growth factor receptor and its ligand, transforming growth factor alpha, in the rat brain. The Journal of comparative neurology. vol 380. issue 2. 1997-06-27. PMID:9100135. |
in the midbrain, the distribution of egf-r mrna overlapped extensively with that of tyrosine hydroxylase mrna, suggesting that fetal dopaminergic neurons express egf-r. immunocytochemistry was used to demonstrate the presence of egf-r-immunoreactive protein in brain areas that expressed egf-r mrna on e15 and e20. |
1997-06-27 |
2023-08-12 |
rat |
| S Numan, K B Seroog. Increased expression of trkB mRNA in rat caudate--putamen following 6-OHDA lesions of the nigrostriatal pathway. The European journal of neuroscience. vol 9. issue 3. 1997-06-27. PMID:9104591. |
these data suggest that midbrain dopaminergic afferents regulate the expression of trkb mrna in the caudate-putamen. |
1997-06-27 |
2023-08-12 |
rat |
| S Numan, K B Seroog. Increased expression of trkB mRNA in rat caudate--putamen following 6-OHDA lesions of the nigrostriatal pathway. The European journal of neuroscience. vol 9. issue 3. 1997-06-27. PMID:9104591. |
alternatively, since dopaminergic neurons of the ventral mesencephalon express bdnf mrna, the up-regulation of striatal trkb mrna may reflect a compensatory response by striatal neurons due to a loss of anterogradely and/or retrogradely derived trophic support from the ventral midbrain. |
1997-06-27 |
2023-08-12 |
rat |
| K Krieglstein, D Maysinger, K Unsicke. The survival response of mesencephalic dopaminergic neurons to the neurotrophins BDNF and NT-4 requires priming with serum: comparison with members of the TGF-beta superfamily and characterization of the serum-free culture system. Journal of neural transmission. Supplementum. vol 47. 1997-06-11. PMID:8841970. |
the neurotrophins, brain-derived neurotrophic factor (bdnf) and neurotrophin-4 (nt-4), are established survival promoting molecules for dopaminergic (daergic) neurons cultured from the fetal rat midbrain floor. |
1997-06-11 |
2023-08-12 |
rat |
| N E Saadé, S F Atweh, N B Bahuth, S J Jabbu. Augmentation of nociceptive reflexes and chronic deafferentation pain by chemical lesions of either dopaminergic terminals or midbrain dopaminergic neurons. Brain research. vol 751. issue 1. 1997-06-09. PMID:9098562. |
augmentation of nociceptive reflexes and chronic deafferentation pain by chemical lesions of either dopaminergic terminals or midbrain dopaminergic neurons. |
1997-06-09 |
2023-08-12 |
rat |
| N E Saadé, S F Atweh, N B Bahuth, S J Jabbu. Augmentation of nociceptive reflexes and chronic deafferentation pain by chemical lesions of either dopaminergic terminals or midbrain dopaminergic neurons. Brain research. vol 751. issue 1. 1997-06-09. PMID:9098562. |
neurodegenerative diseases affecting the midbrain dopaminergic system have been reported to produce spontaneous pains like in parkinson's disease. |
1997-06-09 |
2023-08-12 |
rat |
| J Pierre, M Mahouche, E I Suderevskaya, J Repérant, R War. Immunocytochemical localization of dopamine and its synthetic enzymes in the central nervous system of the lamprey Lampetra fluviatilis. The Journal of comparative neurology. vol 380. issue 1. 1997-06-06. PMID:9073087. |
the dopaminergic system of the lamprey appears to share many features not only with that of other anamniotes but also with that of amniotes; however, as in teleosts, dopaminergic neurons in the midbrain corresponding to the substantia nigra, the retrorubral area, and the ventral tegmental area of other species do not exist in the lamprey. |
1997-06-06 |
2023-08-12 |
Not clear |
| T Verina, J A Norton, J J Sorbel, L C Triarhou, D Laferty, J A Richter, J R Simon, B Ghett. Atrophy and loss of dopaminergic mesencephalic neurons in heterozygous weaver mice. Experimental brain research. vol 113. issue 1. 1997-05-29. PMID:9028770. |
the phenotypic effect of the weaver mutation in the ventral midbrain of homozygous mutants is associated with the progressive loss of dopaminergic neurons. |
1997-05-29 |
2023-08-12 |
mouse |
| L Björklund, I Strömber. Dopaminergic innervation of striatal grafts placed into different sites of normal striatum: differences in the tyrosine hydroxylase immunoreactive growth pattern. Experimental brain research. vol 113. issue 1. 1997-05-29. PMID:9028771. |
in this study the goal was to examine whether the different subgroups of dopaminergic neurons in the ventral mesencephalon projecting to the basal ganglia have different sprouting capacities when stimulated by the trophic effect of a fetal striatal graft. |
1997-05-29 |
2023-08-12 |
rat |
| D A McRitchie, H R Cartwright, G M Hallida. Specific A10 dopaminergic nuclei in the midbrain degenerate in Parkinson's disease. Experimental neurology. vol 144. issue 1. 1997-05-20. PMID:9126172. |
specific a10 dopaminergic nuclei in the midbrain degenerate in parkinson's disease. |
1997-05-20 |
2023-08-12 |
Not clear |
| D A McRitchie, H R Cartwright, G M Hallida. Specific A10 dopaminergic nuclei in the midbrain degenerate in Parkinson's disease. Experimental neurology. vol 144. issue 1. 1997-05-20. PMID:9126172. |
using unbiased quantitative techniques, we evaluated the effect of parkinson's disease on the regional size and the number of tyrosine hydroxylase-producing neurons and all neurons in the midbrain a8 and a10 dopaminergic cell groups located adjacent to the substantia nigra. |
1997-05-20 |
2023-08-12 |
Not clear |
| J Engele, H Rieck, D Choi-Lundberg, M C Boh. Evidence for a novel neurotrophic factor for dopaminergic neurons secreted from mesencephalic glial cell lines. Journal of neuroscience research. vol 43. issue 5. 1997-05-15. PMID:8833092. |
media conditioned by these cell lines were tested for survival-promoting effects on dopaminergic neurons in serum-free cultures of the dissociated e14.5 rat mesencephalon. |
1997-05-15 |
2023-08-12 |
rat |
| J Engele, H Rieck, D Choi-Lundberg, M C Boh. Evidence for a novel neurotrophic factor for dopaminergic neurons secreted from mesencephalic glial cell lines. Journal of neuroscience research. vol 43. issue 5. 1997-05-15. PMID:8833092. |
moreover, treatment of serum-free cultures of the dissociated e14.5 mesencephalon with glial cell line-cm conditioned medium (cm) delayed dopaminergic cell death in a dose-dependent manner, resulting in a maximal twofold to sixfold increase in the number of surviving tyrosine hydroxylase-ir neurons at various days in vitro. |
1997-05-15 |
2023-08-12 |
rat |
| M S Airaksinen, H Thoenen, M Meye. Vulnerability of midbrain dopaminergic neurons in calbindin-D28k-deficient mice: lack of evidence for a neuroprotective role of endogenous calbindin in MPTP-treated and weaver mice. The European journal of neuroscience. vol 9. issue 1. 1997-05-15. PMID:9042576. |
vulnerability of midbrain dopaminergic neurons in calbindin-d28k-deficient mice: lack of evidence for a neuroprotective role of endogenous calbindin in mptp-treated and weaver mice. |
1997-05-15 |
2023-08-12 |
mouse |
| R P Gaykema, L Zaborszk. Parvalbumin-containing neurons in the basal forebrain receive direct input from the substantia nigra-ventral tegmental area. Brain research. vol 747. issue 1. 1997-05-14. PMID:9042545. |
pv-containing neurons in pallidal and adjacent basal forebrain territories are thus directly targeted by presumably a9-a10 dopaminergic neurons and represent a novel aspect of midbrain dopaminergic control of basal forebrain neuronal activity. |
1997-05-14 |
2023-08-12 |
Not clear |