| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elpida Tsika, Meghna Kannan, Caroline Shi-Yan Foo, Dustin Dikeman, Liliane Glauser, Sandra Gellhaar, Dagmar Galter, Graham W Knott, Ted M Dawson, Valina L Dawson, Darren J Moor. Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration. Neurobiology of disease. vol 71. 2015-06-02. PMID:25174890. |
in addition, r1441c lrrk2 mice display increased neurite complexity of cultured midbrain dopaminergic neurons. |
2015-06-02 |
2023-08-13 |
mouse |
| Hany E S Marei, Samah Lashen, Amany Farag, Asmaa Althani, Nahla Afifi, Abd-Elmaksoud A, Shaymaa Rezk, Roberto Pallini, Patrizia Casalbore, Carlo Cenciarell. Human olfactory bulb neural stem cells mitigate movement disorders in a rat model of Parkinson's disease. Journal of cellular physiology. vol 230. issue 7. 2015-06-02. PMID:25536543. |
parkinson's disease (pd) is a neurological disorder characterized by the loss of midbrain dopaminergic (da) neurons. |
2015-06-02 |
2023-08-13 |
human |
| Yu-Rim Kwon, Myong-Ho Jeong, Young-Eun Leem, Sang-Jin Lee, Hyun-Jin Kim, Gyu-Un Bae, Jong-Sun Kan. The Shh coreceptor Cdo is required for differentiation of midbrain dopaminergic neurons. Stem cell research. vol 13. issue 2. 2015-05-29. PMID:25117422. |
the shh coreceptor cdo is required for differentiation of midbrain dopaminergic neurons. |
2015-05-29 |
2023-08-13 |
Not clear |
| Yu-Rim Kwon, Myong-Ho Jeong, Young-Eun Leem, Sang-Jin Lee, Hyun-Jin Kim, Gyu-Un Bae, Jong-Sun Kan. The Shh coreceptor Cdo is required for differentiation of midbrain dopaminergic neurons. Stem cell research. vol 13. issue 2. 2015-05-29. PMID:25117422. |
sonic hedgehog (shh) signaling is required for numerous developmental processes including specification of ventral cell types in the central nervous system such as midbrain dopaminergic (da) neurons. |
2015-05-29 |
2023-08-13 |
Not clear |
| Daisuke Doi, Bumpei Samata, Mitsuko Katsukawa, Tetsuhiro Kikuchi, Asuka Morizane, Yuichi Ono, Kiyotoshi Sekiguchi, Masato Nakagawa, Malin Parmar, Jun Takahash. Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation. Stem cell reports. vol 2. issue 3. 2015-05-22. PMID:24672756. |
human induced pluripotent stem cells (ipscs) can provide a promising source of midbrain dopaminergic (da) neurons for cell replacement therapy for parkinson's disease. |
2015-05-22 |
2023-08-12 |
human |
| Reka Daniel, Stefan Pollman. A universal role of the ventral striatum in reward-based learning: evidence from human studies. Neurobiology of learning and memory. vol 114. 2015-05-22. PMID:24825620. |
electrophysiological recordings of dopaminergic midbrain neurons have shown that they code the difference between actual and predicted rewards, i.e., the reward prediction error, in many species. |
2015-05-22 |
2023-08-13 |
human |
| Reka Daniel, Stefan Pollman. A universal role of the ventral striatum in reward-based learning: evidence from human studies. Neurobiology of learning and memory. vol 114. 2015-05-22. PMID:24825620. |
while results from electrophysiological recordings in humans are sparse, evidence linking dopaminergic activity to the metabolic signal recorded from the midbrain and striatum with functional magnetic resonance imaging (fmri) is available. |
2015-05-22 |
2023-08-13 |
human |
| Chun-Ling Wei, Zhi-Qiang Liu, Yi-Hui Liu, Wei Re. [High-frequency stimulation on cell soma induces potentiation of intrinsic excitability in VTA dopaminergic neurons]. Sheng li xue bao : [Acta physiologica Sinica]. vol 65. issue 1. 2015-05-16. PMID:23426514. |
whole-cell patch-clamping was performed on vta dopaminergic neurons in midbrain slices bathed with ptx, ap-5 and cnqx, and hfs was introduced to cell soma. |
2015-05-16 |
2023-08-12 |
Not clear |
| Vishnu P Murty, Maheen Shermohammed, David V Smith, R McKell Carter, Scott A Huettel, R Alison Adcoc. Resting state networks distinguish human ventral tegmental area from substantia nigra. NeuroImage. vol 100. 2015-05-12. PMID:24979343. |
multiple organizational schemes based on anatomy and function have been proposed for dopaminergic nuclei in the midbrain. |
2015-05-12 |
2023-08-13 |
human |
| Vishnu P Murty, Maheen Shermohammed, David V Smith, R McKell Carter, Scott A Huettel, R Alison Adcoc. Resting state networks distinguish human ventral tegmental area from substantia nigra. NeuroImage. vol 100. 2015-05-12. PMID:24979343. |
we asked whether functional definition of networks within the human dopaminergic midbrain would recapitulate this traditional anatomical topology. |
2015-05-12 |
2023-08-13 |
human |
| Vishnu P Murty, Maheen Shermohammed, David V Smith, R McKell Carter, Scott A Huettel, R Alison Adcoc. Resting state networks distinguish human ventral tegmental area from substantia nigra. NeuroImage. vol 100. 2015-05-12. PMID:24979343. |
next, we constructed a probabilistic atlas of the vta, sn, and the dopaminergic midbrain region (comprised of sn plus vta) from individual hand-drawn rois. |
2015-05-12 |
2023-08-13 |
human |
| N Kanagaraj, H Beiping, S T Dheen, S S W Ta. Downregulation of miR-124 in MPTP-treated mouse model of Parkinson's disease and MPP iodide-treated MN9D cells modulates the expression of the calpain/cdk5 pathway proteins. Neuroscience. vol 272. 2015-05-11. PMID:24792712. |
parkinson's disease (pd) is a debilitating neurodegenerative disorder causing severe motor disabilities resulting from the loss of dopaminergic neurons in the substantia nigra pars compacta (snc) region of the midbrain. |
2015-05-11 |
2023-08-13 |
mouse |
| I V Romanova, A L Mikhrina, M P Chernyshev. [Analysis of development of morphofunctional interconnections between CART- and AGRP-ergic neurons with dopaminergic structures in ontogenesis of mammals]. Zhurnal evoliutsionnoi biokhimii i fiziologii. vol 50. issue 5. 2015-04-24. PMID:25786322. |
analysis of literature and re- sults of our own investigation show that differentiation of dopaminergic neurons in hypothalamus and midbrain occurs on the background of development of cartergic neurons and in the absence of agrp. |
2015-04-24 |
2023-08-13 |
rat |
| Chathurini V Fernando, Julianna Kele, Christopher R Bye, Jonathan C Niclis, Walaa Alsanie, Brette D Blakely, Jan Stenman, Brad J Turner, Clare L Paris. Diverse roles for Wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesis. Stem cells and development. vol 23. issue 17. 2015-04-22. PMID:24803261. |
diverse roles for wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesis. |
2015-04-22 |
2023-08-13 |
mouse |
| Chathurini V Fernando, Julianna Kele, Christopher R Bye, Jonathan C Niclis, Walaa Alsanie, Brette D Blakely, Jan Stenman, Brad J Turner, Clare L Paris. Diverse roles for Wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesis. Stem cells and development. vol 23. issue 17. 2015-04-22. PMID:24803261. |
while a number of regulators of ventral midbrain (vm) neurogenesis and dopaminergic (da) axon guidance are known, we identify a number of novel roles for the secreted glycoprotein, wnt7a, in this context. |
2015-04-22 |
2023-08-13 |
mouse |
| Jie Li, Terence Duarte, Arif Kocabas, Melissa Works, Susan K McConnell, Mary A Hyne. Evidence for topographic guidance of dopaminergic axons by differential Netrin-1 expression in the striatum. Molecular and cellular neurosciences. vol 61. 2015-04-15. PMID:24867253. |
there are two main subgroups of midbrain dopaminergic (da) neurons: the more medially located ventral tegmental area (vta) da neurons, which have axons that innervate the ventral-lateral (vl) striatum, and the more laterally located substantia nigra (sn) da neurons, which preferentially degenerate in parkinson's disease (pd) and have axons that project to the dorsal-medial (dm) striatum. |
2015-04-15 |
2023-08-13 |
mouse |
| Itzel Escobedo-Avila, Fernanda Vargas-Romero, Anayansi Molina-Hernández, Rodrigo López-González, Daniel Cortés, Juan A De Carlos, Iván Velasc. Histamine impairs midbrain dopaminergic development in vivo by activating histamine type 1 receptors. Molecular brain. vol 7. 2015-04-15. PMID:25112718. |
histamine impairs midbrain dopaminergic development in vivo by activating histamine type 1 receptors. |
2015-04-15 |
2023-08-13 |
Not clear |
| Itzel Escobedo-Avila, Fernanda Vargas-Romero, Anayansi Molina-Hernández, Rodrigo López-González, Daniel Cortés, Juan A De Carlos, Iván Velasc. Histamine impairs midbrain dopaminergic development in vivo by activating histamine type 1 receptors. Molecular brain. vol 7. 2015-04-15. PMID:25112718. |
dopaminergic specification in the embryonic ventral midbrain (vm) coincides with increased ha brain levels. |
2015-04-15 |
2023-08-13 |
Not clear |
| Bradley Watmuff, Brigham J Hartley, Cameron P J Hunt, Stewart A Fabb, Colin W Pouton, John M Hayne. Human pluripotent stem cell derived midbrain PITX3(eGFP/w) neurons: a versatile tool for pharmacological screening and neurodegenerative modeling. Frontiers in cellular neuroscience. vol 9. 2015-04-15. PMID:25873861. |
pitx3 expression is confined to adult midbrain dopaminergic (mda) neurons. |
2015-04-15 |
2023-08-13 |
human |
| Er-song Wang, Xiao-ping Zhang, Hui-bin Yao, Gan Wang, Shi-wen Chen, Wen-wei Gao, Hai-jun Yao, Yi-rui Sun, Cai-hua Xi, Yao-dong J. Tetranectin knockout mice develop features of Parkinson disease. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 34. issue 2. 2015-04-13. PMID:25033953. |
aggregation of insoluble α-synuclein to form lewy bodies (lbs) may contribute to the selective loss of midbrain dopaminergic neurons in parkinson disease (pd). |
2015-04-13 |
2023-08-13 |
mouse |