| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elizabeth M Hartfield, Michiko Yamasaki-Mann, Hugo J Ribeiro Fernandes, Jane Vowles, William S James, Sally A Cowley, Richard Wade-Martin. Physiological characterisation of human iPS-derived dopaminergic neurons. PloS one. vol 9. issue 2. 2015-01-02. PMID:24586273. |
this is of particular relevance to research into neurological disease, such as parkinson's disease (pd), in which midbrain dopaminergic neurons degenerate during disease progression but are unobtainable until post-mortem. |
2015-01-02 |
2023-08-12 |
human |
| Elizabeth M Hartfield, Michiko Yamasaki-Mann, Hugo J Ribeiro Fernandes, Jane Vowles, William S James, Sally A Cowley, Richard Wade-Martin. Physiological characterisation of human iPS-derived dopaminergic neurons. PloS one. vol 9. issue 2. 2015-01-02. PMID:24586273. |
we first generated and differentiated hipsc lines into midbrain dopaminergic neurons and performed a comprehensive characterisation to confirm dopaminergic functionality by demonstrating dopamine synthesis, release, and re-uptake. |
2015-01-02 |
2023-08-12 |
human |
| Candan Depboyl. Non-serine-phosphorylated tyrosine hydroxylase expressing neurons are present in mouse striatum, accumbens and cortex that increase in number following dopaminergic denervation. Journal of chemical neuroanatomy. vol 56. 2014-12-18. PMID:24553202. |
this current study analyzed if th neurons exist in target areas of ventral midbrain dopaminergic neurons and how they react to dopaminergic denervation. |
2014-12-18 |
2023-08-12 |
mouse |
| Iria G Dopeso-Reyes, Alberto J Rico, Elvira Roda, Salvador Sierra, Diego Pignataro, Maria Lanz, Diego Sucunza, Luis Chang-Azancot, Jose L Lancieg. Calbindin content and differential vulnerability of midbrain efferent dopaminergic neurons in macaques. Frontiers in neuroanatomy. vol 8. 2014-12-18. PMID:25520629. |
calbindin content and differential vulnerability of midbrain efferent dopaminergic neurons in macaques. |
2014-12-18 |
2023-08-13 |
monkey |
| Iria G Dopeso-Reyes, Alberto J Rico, Elvira Roda, Salvador Sierra, Diego Pignataro, Maria Lanz, Diego Sucunza, Luis Chang-Azancot, Jose L Lancieg. Calbindin content and differential vulnerability of midbrain efferent dopaminergic neurons in macaques. Frontiers in neuroanatomy. vol 8. 2014-12-18. PMID:25520629. |
next, we have elucidated the presence of cb within identified nigrostriatal and nigroextrastriatal midbrain dopaminergic projection neurons. |
2014-12-18 |
2023-08-13 |
monkey |
| Erica L Unger, Laura E Bianco, Byron C Jones, Richard P Allen, Christopher J Earle. Low brain iron effects and reversibility on striatal dopamine dynamics. Experimental neurology. vol 261. 2014-12-17. PMID:24999026. |
iron deficiency (id) in rodents leads to decreased ventral midbrain (vmb) iron concentrations and to changes in the dopamine (da) system that mimic many of the dopaminergic changes seen in rls patient where low substantia nigra iron is a known pathology of the disease. |
2014-12-17 |
2023-08-13 |
rat |
| Elisabeth Piccart, Jean-François De Backer, David Gall, Laurie Lambot, Adam Raes, Greet Vanhoof, Serge Schiffmann, Rudi D'Hoog. Genetic deletion of PDE10A selectively impairs incentive salience attribution and decreases medium spiny neuron excitability. Behavioural brain research. vol 268. 2014-12-16. PMID:24698799. |
the numerous spines on their dendrites render them capable of integrating cortical glutamatergic inputs with a motivational dopaminergic signal that originates in the midbrain. |
2014-12-16 |
2023-08-13 |
mouse |
| Florence Gaven, Philippe Marin, Sylvie Claeyse. Primary culture of mouse dopaminergic neurons. Journal of visualized experiments : JoVE. issue 91. 2014-12-15. PMID:25226064. |
precise excision of ventral mesencephalon is crucial to obtain neuronal cultures sufficiently rich in dopaminergic cells to allow subsequent studies. |
2014-12-15 |
2023-08-13 |
mouse |
| Mei Yeng Yew, Rhun Yian Koh, Soi Moi Chye, Iekhsan Othman, Khuen Yen N. Edible bird's nest ameliorates oxidative stress-induced apoptosis in SH-SY5Y human neuroblastoma cells. BMC complementary and alternative medicine. vol 14. 2014-12-12. PMID:25308934. |
reactive oxygen species (ros) is implicated in the progression of oxidative stress-related apoptosis and cell death of the midbrain dopaminergic neurons. |
2014-12-12 |
2023-08-13 |
human |
| Alla Narytnyk, Bernard Verdon, Andrew Loughney, Michele Sweeney, Oliver Clewes, Michael J Taggart, Maya Sieber-Blu. Differentiation of human epidermal neural crest stem cells (hEPI-NCSC) into virtually homogenous populations of dopaminergic neurons. Stem cell reviews and reports. vol 10. issue 2. 2014-12-09. PMID:24399192. |
here we provide a protocol for the directed differentiation of hepi-ncsc into midbrain dopaminergic neurons, which degenerate in parkinson's disease. |
2014-12-09 |
2023-08-12 |
human |
| Günter U Höglinger, Oscar Arias-Carrión, Bastian Ipach, Wolfgang H Oerte. Origin of the dopaminergic innervation of adult neurogenic areas. The Journal of comparative neurology. vol 522. issue 10. 2014-12-09. PMID:24424877. |
postmortem anterograde and retrograde tracing combined with immunofluorescence procedures indicate a topographic organization of midbrain dopaminergic projections toward the svz. |
2014-12-09 |
2023-08-12 |
human |
| Yoo-Wook Kwon, Yeon-Ju Chung, Joonoh Kim, Ho-Jae Lee, Jihwan Park, Tae-Young Roh, Hyun-Jai Cho, Chang-Hwan Yoon, Bon-Kwon Koo, Hyo-Soo Ki. Comparative study of efficacy of dopaminergic neuron differentiation between embryonic stem cell and protein-based induced pluripotent stem cell. PloS one. vol 9. issue 1. 2014-12-03. PMID:24465672. |
here, we differentiated two types of stem cells; mouse embryonic stem cells (mescs) and protein-based ips cells (p-ipscs) generated by non-viral methods, into midbrain dopaminergic (mda) neurons, and then compared the efficiency of da neuron differentiation from these two cell types. |
2014-12-03 |
2023-08-12 |
mouse |
| Katharine V Northcutt, Jennifer M K Nguye. Female juvenile play elicits Fos expression in dopaminergic neurons of the VTA. Behavioral neuroscience. vol 128. issue 2. 2014-12-03. PMID:24773437. |
cells expressing both proteins were counted in midbrain and forebrain dopaminergic cell groups. |
2014-12-03 |
2023-08-13 |
human |
| Ilona Klejbor, Beata Ludkiewicz, Sławomir Wojcik, Krzysztof Turlejsk. Correlation between dopaminergic phenotype and expression of calretinin in the midbrain nuclei of the opossum (Monodelphis domestica): an immunohistological study. Acta neurobiologiae experimentalis. vol 73. issue 4. 2014-11-21. PMID:24457643. |
correlation between dopaminergic phenotype and expression of calretinin in the midbrain nuclei of the opossum (monodelphis domestica): an immunohistological study. |
2014-11-21 |
2023-08-12 |
Not clear |
| Boyu Li, Yuhe Yuan, Wanqing Zhang, Wenbin He, Jinfeng Hu, Naihong Che. Flavin-containing monooxygenase, a new clue of pathological proteins in the rotenone model of parkinsonism. Neuroscience letters. vol 566. 2014-11-11. PMID:24440618. |
thus we successfully generated rotenone model in primary midbrain dopaminergic neurons and identified the apoptosis of neurons caused by rotenone. |
2014-11-11 |
2023-08-12 |
Not clear |
| K Göbel, C Er. [Neurological disorders and glaucoma - an overview]. Klinische Monatsblatter fur Augenheilkunde. vol 231. issue 2. 2014-11-05. PMID:24532400. |
parkinson's disease is characterised by a loss of dopaminergic neurons in the basal ganglia-substantia nigra pars compacta of the midbrain. |
2014-11-05 |
2023-08-12 |
Not clear |
| M O Guloglu, A Larsen, P Brundi. Adipocytes derived from PA6 cells reliably promote the differentiation of dopaminergic neurons from human embryonic stem cells. Journal of neuroscience research. vol 92. issue 5. 2014-11-04. PMID:24482287. |
furthermore, we report that the coculture of human embryonic stem cells with pa6-derived adipocytes reliably induces their differentiation into midbrain dopaminergic neurons. |
2014-11-04 |
2023-08-12 |
mouse |
| M J Tobia, R Guo, U Schwarze, W Boehmer, J Gläscher, B Finckh, A Marschner, C Büchel, K Obermayer, T Somme. Neural systems for choice and valuation with counterfactual learning signals. NeuroImage. vol 89. 2014-10-29. PMID:24321554. |
the depletion procedure revealed significantly different neural responses to expected value in the vmpfc, caudate, and dopaminergic midbrain in the vicinity of the substantia nigra (sn). |
2014-10-29 |
2023-08-12 |
human |
| Matteo Colomb. Deep and beautiful. The reward prediction error hypothesis of dopamine. Studies in history and philosophy of biological and biomedical sciences. vol 45. 2014-10-22. PMID:24252364. |
according to the reward-prediction error hypothesis (rpeh) of dopamine, the phasic activity of dopaminergic neurons in the midbrain signals a discrepancy between the predicted and currently experienced reward of a particular event. |
2014-10-22 |
2023-08-12 |
Not clear |
| Alan D Pickering, Francesca Pesol. Modeling dopaminergic and other processes involved in learning from reward prediction error: contributions from an individual differences perspective. Frontiers in human neuroscience. vol 8. 2014-10-17. PMID:25324752. |
in particular, variations in the strength of connections carrying excitatory reward drive inputs to midbrain dopaminergic cells were considered plausible candidates, along with variations in a parameter which scales the effects of dopamine cell firing bursts on synaptic modification in ventral striatum. |
2014-10-17 |
2023-08-13 |
Not clear |