| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jacopo C DiFrancesco, Dario DiFrancesc. Dysfunctional HCN ion channels in neurological diseases. Frontiers in cellular neuroscience. vol 6. 2015-03-25. PMID:25805968. |
hcn channels are also present in the midbrain system, where they finely regulate the activity of dopaminergic neurons, and a potential role of these channels in the pathogenesis of parkinson's disease has recently emerged. |
2015-03-25 |
2023-08-13 |
Not clear |
| Michelle Healy-Stoffel, S Omar Ahmad, John A Stanford, Beth Levan. Differential effects of intrastriatal 6-hydroxydopamine on cell number and morphology in midbrain dopaminergic subregions of the rat. Brain research. vol 1574. 2015-02-26. PMID:24924804. |
differential effects of intrastriatal 6-hydroxydopamine on cell number and morphology in midbrain dopaminergic subregions of the rat. |
2015-02-26 |
2023-08-13 |
rat |
| Michelle Healy-Stoffel, S Omar Ahmad, John A Stanford, Beth Levan. Differential effects of intrastriatal 6-hydroxydopamine on cell number and morphology in midbrain dopaminergic subregions of the rat. Brain research. vol 1574. 2015-02-26. PMID:24924804. |
the midbrain dopaminergic perikarya are differentially affected in parkinson׳s disease (pd). |
2015-02-26 |
2023-08-13 |
rat |
| Cameron P Hunt, Stewart A Fabb, Colin W Pouton, John M Hayne. DNA-dependent protein kinase is a context dependent regulator of Lmx1a and midbrain specification. PloS one. vol 8. issue 10. 2015-02-24. PMID:24194952. |
within neural progenitors, lim homeobox transcription factor 1 alpha (lmx1a) is required for proper development of roof plate and cortical hem structures of the forebrain, as well as the development of floor plate and midbrain dopaminergic neurons. |
2015-02-24 |
2023-08-12 |
mouse |
| Kaustuv Saha, Danielle Sambo, Ben D Richardson, Landon M Lin, Brittany Butler, Laura Villarroel, Habibeh Khoshboue. Intracellular methamphetamine prevents the dopamine-induced enhancement of neuronal firing. The Journal of biological chemistry. vol 289. issue 32. 2015-02-19. PMID:24962577. |
we further examined the unique mechanisms by which amphetamine and methamphetamine regulate dat function and dopamine neurotransmission; in the present study we examined the impact of extracellular and intracellular amphetamine and methamphetamine on the spontaneous firing of cultured midbrain dopaminergic neurons and isolated dat-mediated current. |
2015-02-19 |
2023-08-13 |
Not clear |
| Erin S Calipari, Haiguo Sun, Khalil Eldeeb, Deborah J Luessen, Xin Feng, Allyn C Howlett, Sara R Jones, Rong Che. Amphetamine self-administration attenuates dopamine D2 autoreceptor function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 8. 2015-02-12. PMID:24513972. |
dopamine d2 autoreceptors located on the midbrain dopaminergic neurons modulate dopamine (da) neuron firing, da release, and da synthesis through a negative-feedback mechanism. |
2015-02-12 |
2023-08-12 |
Not clear |
| Michael S Cohen, Jesse Rissman, Nanthia A Suthana, Alan D Castel, Barbara J Knowlto. Value-based modulation of memory encoding involves strategic engagement of fronto-temporal semantic processing regions. Cognitive, affective & behavioral neuroscience. vol 14. issue 2. 2015-02-09. PMID:24683066. |
a number of prior fmri studies have focused on the ways in which the midbrain dopaminergic reward system coactivates with hippocampus to potentiate memory for valuable items. |
2015-02-09 |
2023-08-12 |
human |
| Jia Liu, Bangfu Zhu, Gaofeng Zhang, Jian Wang, Weiming Tian, Gong Ju, Xiaoqing Wei, Bing Son. Electric signals regulate directional migration of ventral midbrain derived dopaminergic neural progenitor cells via Wnt/GSK3β signaling. Experimental neurology. vol 263. 2015-02-09. PMID:25265211. |
electric signals regulate directional migration of ventral midbrain derived dopaminergic neural progenitor cells via wnt/gsk3β signaling. |
2015-02-09 |
2023-08-13 |
Not clear |
| Colin G McNamara, Álvaro Tejero-Cantero, Stéphanie Trouche, Natalia Campo-Urriza, David Dupre. Dopaminergic neurons promote hippocampal reactivation and spatial memory persistence. Nature neuroscience. vol 17. issue 12. 2015-02-06. PMID:25326690. |
we found that optogenetic burst stimulation of hippocampal dopaminergic fibers from midbrain neurons in mice exploring novel environments enhanced the reactivation of pyramidal cell assemblies during subsequent sleep/rest. |
2015-02-06 |
2023-08-13 |
mouse |
| Colin G McNamara, Álvaro Tejero-Cantero, Stéphanie Trouche, Natalia Campo-Urriza, David Dupre. Dopaminergic neurons promote hippocampal reactivation and spatial memory persistence. Nature neuroscience. vol 17. issue 12. 2015-02-06. PMID:25326690. |
these findings reveal that midbrain dopaminergic neurons promote hippocampal network dynamics associated with memory persistence. |
2015-02-06 |
2023-08-13 |
mouse |
| Vannary Tieng, Luc Stoppini, Sabrina Villy, Marc Fathi, Michel Dubois-Dauphin, Karl-Heinz Kraus. Engineering of midbrain organoids containing long-lived dopaminergic neurons. Stem cells and development. vol 23. issue 13. 2015-02-05. PMID:24576173. |
engineering of midbrain organoids containing long-lived dopaminergic neurons. |
2015-02-05 |
2023-08-12 |
Not clear |
| Wen-Ting Hsieh, Been-Huang Chian. A well-refined in vitro model derived from human embryonic stem cell for screening phytochemicals with midbrain dopaminergic differentiation-boosting potential for improving Parkinson's disease. Journal of agricultural and food chemistry. vol 62. issue 27. 2015-02-02. PMID:24933592. |
a well-refined in vitro model derived from human embryonic stem cell for screening phytochemicals with midbrain dopaminergic differentiation-boosting potential for improving parkinson's disease. |
2015-02-02 |
2023-08-13 |
human |
| Wen-Ting Hsieh, Been-Huang Chian. A well-refined in vitro model derived from human embryonic stem cell for screening phytochemicals with midbrain dopaminergic differentiation-boosting potential for improving Parkinson's disease. Journal of agricultural and food chemistry. vol 62. issue 27. 2015-02-02. PMID:24933592. |
this objective was to establish an in vitro model by differentiating pluripotent human embryonic stem cells (hescs) into midbrain dopaminergic (mda) neurons for screening phytochemicals with mda neurogenesis-boosting potentials. |
2015-02-02 |
2023-08-13 |
human |
| Vanessa H Rausch, Eva M Bauch, Nico Bunzec. White noise improves learning by modulating activity in dopaminergic midbrain regions and right superior temporal sulcus. Journal of cognitive neuroscience. vol 26. issue 7. 2015-01-09. PMID:24345178. |
white noise improves learning by modulating activity in dopaminergic midbrain regions and right superior temporal sulcus. |
2015-01-09 |
2023-08-12 |
Not clear |
| Vanessa H Rausch, Eva M Bauch, Nico Bunzec. White noise improves learning by modulating activity in dopaminergic midbrain regions and right superior temporal sulcus. Journal of cognitive neuroscience. vol 26. issue 7. 2015-01-09. PMID:24345178. |
here, on the basis of recent theories, we tested the hypothesis that auditory white noise, when presented during the encoding of scene images, enhances subsequent recognition memory performance and modulates activity within the dopaminergic midbrain (i.e., substantia nigra/ventral tegmental area, sn/vta). |
2015-01-09 |
2023-08-12 |
Not clear |
| Vanessa H Rausch, Eva M Bauch, Nico Bunzec. White noise improves learning by modulating activity in dopaminergic midbrain regions and right superior temporal sulcus. Journal of cognitive neuroscience. vol 26. issue 7. 2015-01-09. PMID:24345178. |
our results suggest that the beneficial effects of auditory white noise on learning depend on dopaminergic neuromodulation and enhanced connectivity between midbrain regions and the sts-a key player in attention modulation. |
2015-01-09 |
2023-08-12 |
Not clear |
| Javier Blesa, Serge Przedborsk. Parkinson's disease: animal models and dopaminergic cell vulnerability. Frontiers in neuroanatomy. vol 8. 2015-01-08. PMID:25565980. |
understanding the variable vulnerability of the dopaminergic neurons from the midbrain and the mechanisms whereby pathology becomes widespread are some of the primary objectives of research in pd. |
2015-01-08 |
2023-08-13 |
human |
| Javier Blesa, Serge Przedborsk. Parkinson's disease: animal models and dopaminergic cell vulnerability. Frontiers in neuroanatomy. vol 8. 2015-01-08. PMID:25565980. |
in this review, we provide a summary of our current knowledge about the different in vivo models of pd that are used in relation to the vulnerability of the dopaminergic neurons in the midbrain in the pathogenesis of pd. |
2015-01-08 |
2023-08-13 |
human |
| Shane V Hegarty, Louise M Collins, Aisling M Gavin, Sarah L Roche, Sean L Wyatt, Aideen M Sullivan, Gerard W O'Keeff. Canonical BMP-Smad signalling promotes neurite growth in rat midbrain dopaminergic neurons. Neuromolecular medicine. vol 16. issue 2. 2015-01-05. PMID:24682653. |
canonical bmp-smad signalling promotes neurite growth in rat midbrain dopaminergic neurons. |
2015-01-05 |
2023-08-12 |
rat |
| Shane V Hegarty, Louise M Collins, Aisling M Gavin, Sarah L Roche, Sean L Wyatt, Aideen M Sullivan, Gerard W O'Keeff. Canonical BMP-Smad signalling promotes neurite growth in rat midbrain dopaminergic neurons. Neuromolecular medicine. vol 16. issue 2. 2015-01-05. PMID:24682653. |
ventral midbrain (vm) dopaminergic (da) neurons project to the dorsal striatum via the nigrostriatal pathway to regulate voluntary movements, and their loss leads to the motor dysfunction seen in parkinson's disease (pd). |
2015-01-05 |
2023-08-12 |
rat |