Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Christina Krabbe, Sara Thornby Bak, Pia Jensen, Christian von Linstow, Alberto Martínez Serrano, Claus Hansen, Morten Meye. Influence of oxygen tension on dopaminergic differentiation of human fetal stem cells of midbrain and forebrain origin. PloS one. vol 9. issue 5. 2015-06-23. PMID:24788190. |
our data may reflect differences in dopaminergic differentiation capacity and region-specific requirements of nscs, with the dopamine-depleted striatum cultured at low oxygen offering an attractive micro-environment for midbrain nscs. |
2015-06-23 |
2023-08-13 |
mouse |
Candan Depboylu, Thomas W Rösler, Anderson de Andrade, Wolfgang H Oertel, Günter U Höglinge. Systemically administered neuregulin-1β1 rescues nigral dopaminergic neurons via the ErbB4 receptor tyrosine kinase in MPTP mouse models of Parkinson's disease. Journal of neurochemistry. vol 133. issue 4. 2015-06-18. PMID:25581060. |
in conclusion, systemically administered nrg1β1 protects midbrain dopaminergic neurons against this pd-related toxic insult. |
2015-06-18 |
2023-08-13 |
mouse |
Cody A Siciliano, Erin S Calipari, Verginia C Cuzon Carlson, Christa M Helms, David M Lovinger, Kathleen A Grant, Sara R Jone. Voluntary ethanol intake predicts κ-opioid receptor supersensitivity and regionally distinct dopaminergic adaptations in macaques. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 15. 2015-06-18. PMID:25878269. |
the dopaminergic projections from the ventral midbrain to the striatum have long been implicated in mediating motivated behaviors and addiction. |
2015-06-18 |
2023-08-13 |
Not clear |
Ko Miyoshi, Kyosuke Kasahara, Shinki Murakami, Mika Takeshima, Natsuko Kumamoto, Asako Sato, Ikuko Miyazaki, Shinsuke Matsuzaki, Toshikuni Sasaoka, Taiichi Katayama, Masato Asanum. Lack of dopaminergic inputs elongates the primary cilia of striatal neurons. PloS one. vol 9. issue 5. 2015-06-15. PMID:24830745. |
here we investigated the effects of dopaminergic inputs loss on the architecture of neuronal primary cilia in the rodent striatum, a brain region that receives major dopaminergic projections from the midbrain. |
2015-06-15 |
2023-08-13 |
mouse |
Clayton Hickey, Marius V Peele. Neural mechanisms of incentive salience in naturalistic human vision. Neuron. vol 85. issue 3. 2015-06-15. PMID:25654257. |
using multivoxel pattern analysis in visual cortex, we found that the encoding of reward-associated targets was enhanced, whereas encoding of reward-associated distractors was suppressed, with the strength of this effect predicted by activity in the dopaminergic midbrain and a connected cortical network. |
2015-06-15 |
2023-08-13 |
human |
Parinya Noisa, Taneli Raivio, Wei Cu. Neural Progenitor Cells Derived from Human Embryonic Stem Cells as an Origin of Dopaminergic Neurons. Stem cells international. vol 2015. 2015-06-11. PMID:26064138. |
importantly, multiple markers of midbrain neurons were detected, including nurr1, pitx3, and en1, suggesting that hesc-derived dopaminergic neurons attained the midbrain identity. |
2015-06-11 |
2023-08-13 |
human |
Thore Apitz, Nico Bunzec. Early effects of reward anticipation are modulated by dopaminergic stimulation. PloS one. vol 9. issue 10. 2015-06-10. PMID:25285436. |
while the mesolimbic system, including dopaminergic midbrain, ventral striatum and prefrontal cortex have long been associated with reward processing, recent studies also indicate a prominent role of early visual brain regions. |
2015-06-10 |
2023-08-13 |
human |
Akram Mokhtarzadeh Khanghahi, Bahman Zeynali, Azimeh Akhlaghpoor, Azita Parvaneh Tafreshi, Kerstin Krieglstei. Activation of TGFβ1 signaling enhances early dopaminergic differentiation in unrestricted somatic stem cells. Neuroscience letters. vol 583. 2015-06-05. PMID:25233862. |
so far there is increasing evidence for the involvement of transforming growth factor beta tgfβ (transforming growth factor) in differentiation and maintenance of midbrain dopaminergic neurons. |
2015-06-05 |
2023-08-13 |
Not clear |
Daniel G Dillon, Ian G Dobbins, Diego A Pizzagall. Weak reward source memory in depression reflects blunted activation of VTA/SN and parahippocampus. Social cognitive and affective neuroscience. vol 9. issue 10. 2015-06-03. PMID:24078019. |
reward responses in the medial temporal lobes and dopaminergic midbrain boost episodic memory formation in healthy adults, and weak memory for emotionally positive material in depression suggests this mechanism may be dysfunctional in major depressive disorder (mdd). |
2015-06-03 |
2023-08-12 |
human |
Daniel G Dillon, Ian G Dobbins, Diego A Pizzagall. Weak reward source memory in depression reflects blunted activation of VTA/SN and parahippocampus. Social cognitive and affective neuroscience. vol 9. issue 10. 2015-06-03. PMID:24078019. |
consistent with predictions, controls also showed a stronger encoding response to reward tokens vs zero tokens in the right parahippocampus and dopaminergic midbrain, whereas the mdd group showed the opposite pattern-stronger responses to zero vs reward tokens-in these regions. |
2015-06-03 |
2023-08-12 |
human |
Daniel G Dillon, Ian G Dobbins, Diego A Pizzagall. Weak reward source memory in depression reflects blunted activation of VTA/SN and parahippocampus. Social cognitive and affective neuroscience. vol 9. issue 10. 2015-06-03. PMID:24078019. |
differential activation of the dopaminergic midbrain by reward vs zero tokens was positively correlated with the reward source memory advantage in controls, but not depressed participants. |
2015-06-03 |
2023-08-12 |
human |
Daniel G Dillon, Ian G Dobbins, Diego A Pizzagall. Weak reward source memory in depression reflects blunted activation of VTA/SN and parahippocampus. Social cognitive and affective neuroscience. vol 9. issue 10. 2015-06-03. PMID:24078019. |
these data suggest that weaker memory for positive material in depression reflects blunted encoding responses in the dopaminergic midbrain and medial temporal lobes. |
2015-06-03 |
2023-08-12 |
human |
Elpida Tsika, Meghna Kannan, Caroline Shi-Yan Foo, Dustin Dikeman, Liliane Glauser, Sandra Gellhaar, Dagmar Galter, Graham W Knott, Ted M Dawson, Valina L Dawson, Darren J Moor. Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration. Neurobiology of disease. vol 71. 2015-06-02. PMID:25174890. |
conditional expression of parkinson's disease-related r1441c lrrk2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration. |
2015-06-02 |
2023-08-13 |
mouse |
Elpida Tsika, Meghna Kannan, Caroline Shi-Yan Foo, Dustin Dikeman, Liliane Glauser, Sandra Gellhaar, Dagmar Galter, Graham W Knott, Ted M Dawson, Valina L Dawson, Darren J Moor. Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration. Neurobiology of disease. vol 71. 2015-06-02. PMID:25174890. |
in addition, r1441c lrrk2 mice display increased neurite complexity of cultured midbrain dopaminergic neurons. |
2015-06-02 |
2023-08-13 |
mouse |
Hany E S Marei, Samah Lashen, Amany Farag, Asmaa Althani, Nahla Afifi, Abd-Elmaksoud A, Shaymaa Rezk, Roberto Pallini, Patrizia Casalbore, Carlo Cenciarell. Human olfactory bulb neural stem cells mitigate movement disorders in a rat model of Parkinson's disease. Journal of cellular physiology. vol 230. issue 7. 2015-06-02. PMID:25536543. |
parkinson's disease (pd) is a neurological disorder characterized by the loss of midbrain dopaminergic (da) neurons. |
2015-06-02 |
2023-08-13 |
human |
Yu-Rim Kwon, Myong-Ho Jeong, Young-Eun Leem, Sang-Jin Lee, Hyun-Jin Kim, Gyu-Un Bae, Jong-Sun Kan. The Shh coreceptor Cdo is required for differentiation of midbrain dopaminergic neurons. Stem cell research. vol 13. issue 2. 2015-05-29. PMID:25117422. |
the shh coreceptor cdo is required for differentiation of midbrain dopaminergic neurons. |
2015-05-29 |
2023-08-13 |
Not clear |
Yu-Rim Kwon, Myong-Ho Jeong, Young-Eun Leem, Sang-Jin Lee, Hyun-Jin Kim, Gyu-Un Bae, Jong-Sun Kan. The Shh coreceptor Cdo is required for differentiation of midbrain dopaminergic neurons. Stem cell research. vol 13. issue 2. 2015-05-29. PMID:25117422. |
sonic hedgehog (shh) signaling is required for numerous developmental processes including specification of ventral cell types in the central nervous system such as midbrain dopaminergic (da) neurons. |
2015-05-29 |
2023-08-13 |
Not clear |
Daisuke Doi, Bumpei Samata, Mitsuko Katsukawa, Tetsuhiro Kikuchi, Asuka Morizane, Yuichi Ono, Kiyotoshi Sekiguchi, Masato Nakagawa, Malin Parmar, Jun Takahash. Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation. Stem cell reports. vol 2. issue 3. 2015-05-22. PMID:24672756. |
human induced pluripotent stem cells (ipscs) can provide a promising source of midbrain dopaminergic (da) neurons for cell replacement therapy for parkinson's disease. |
2015-05-22 |
2023-08-12 |
human |
Reka Daniel, Stefan Pollman. A universal role of the ventral striatum in reward-based learning: evidence from human studies. Neurobiology of learning and memory. vol 114. 2015-05-22. PMID:24825620. |
electrophysiological recordings of dopaminergic midbrain neurons have shown that they code the difference between actual and predicted rewards, i.e., the reward prediction error, in many species. |
2015-05-22 |
2023-08-13 |
human |
Reka Daniel, Stefan Pollman. A universal role of the ventral striatum in reward-based learning: evidence from human studies. Neurobiology of learning and memory. vol 114. 2015-05-22. PMID:24825620. |
while results from electrophysiological recordings in humans are sparse, evidence linking dopaminergic activity to the metabolic signal recorded from the midbrain and striatum with functional magnetic resonance imaging (fmri) is available. |
2015-05-22 |
2023-08-13 |
human |