| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andreas Hermann, Kai F Loewenbrück, Änne Boldt, Christiane Fiedler, Martina Maisel, Joanna Kalucka, Johannes Schwarz, Georg Breier, Alexander Storc. Lack of vascular endothelial growth factor receptor-2/Flk1 signaling does not affect substantia nigra development. Neuroscience letters. vol 553. 2014-05-08. PMID:23994060. |
lack of hypoxia-inducible factor-1α (hif1α) impairs midbrain dopaminergic neurogenesis which could be rescued by vascular endothelial growth factor (vegf) via vegfr-2 signaling. |
2014-05-08 |
2023-08-12 |
mouse |
| Shujie Wang, Yan Tan, Ju-En Zhang, Minmin Lu. Pharmacogenetic activation of midbrain dopaminergic neurons induces hyperactivity. Neuroscience bulletin. vol 29. issue 5. 2014-05-02. PMID:23516143. |
pharmacogenetic activation of midbrain dopaminergic neurons induces hyperactivity. |
2014-05-02 |
2023-08-12 |
mouse |
| Shujie Wang, Yan Tan, Ju-En Zhang, Minmin Lu. Pharmacogenetic activation of midbrain dopaminergic neurons induces hyperactivity. Neuroscience bulletin. vol 29. issue 5. 2014-05-02. PMID:23516143. |
the results showed that cno selectively activated midbrain dopaminergic neurons and induced hyperactivity in a dose-dependent manner, supporting the idea that these neurons play an important role in regulating motor activity. |
2014-05-02 |
2023-08-12 |
mouse |
| William Omar Contreras Lopez, Guido Nikkhah, Ulf D Kahlert, Donata Maciaczyk, Tomasz Bogiel, Sven Moellers, Elisabeth Schültke, Máté Döbrössy, Jaroslaw Maciaczy. Clinical neurotransplantation protocol for Huntington's and Parkinson's disease. Restorative neurology and neuroscience. vol 31. issue 5. 2014-04-22. PMID:23777636. |
the concept of transplantation of neuronal cells to treat huntington's and parkinson's diseases is based on the proven principle that dopaminergic and gaba-ergic progenitor neurons (from the human developing ventral mesencephalon and whole ganglionic eminence) can survive, differentiate and functionally integrate into an allogenic host brain. |
2014-04-22 |
2023-08-12 |
human |
| Daniel J Foster, Patrick R Gentry, Jose E Lizardi-Ortiz, Thomas M Bridges, Michael R Wood, Colleen M Niswender, David Sulzer, Craig W Lindsley, Zixiu Xiang, P Jeffrey Con. M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 9. 2014-04-22. PMID:24573284. |
of the five muscarinic receptor subtypes, the m5 receptor is the only one detectable in midbrain dopaminergic neurons, making it an attractive potential therapeutic target for treating disorders in which dopaminergic signaling is disrupted. |
2014-04-22 |
2023-08-12 |
mouse |
| Victoria B Gradin, Gordon Waiter, Akira O'Connor, Liana Romaniuk, Catriona Stickle, Keith Matthews, Jeremy Hall, J Douglas Steel. Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia. Psychiatry research. vol 211. issue 2. 2014-04-21. PMID:23146249. |
furthermore, we investigated functional connectivity between the dopaminergic midbrain, a key region for the processing of reinforcers, and other brain regions. |
2014-04-21 |
2023-08-12 |
Not clear |
| M A Fahim, S Shehab, A Nemmar, A Adem, S Dhanasekaran, M Y Hasa. Daily subacute paraquat exposure decreases muscle function and substantia nigra dopamine level. Physiological research. vol 62. issue 3. 2014-04-21. PMID:23489189. |
dopamine concentrations in the ventral mesencephalon were measured by high performance liquid chromatography and the number of dopaminergic neurons in substantia nigra pars compacta was estimated by tyrosine hydroxylase immunohistochemistry. |
2014-04-21 |
2023-08-12 |
rat |
| Michael C Chen, Huan Yu, Zhi-Li Huang, Jun L. Rapid eye movement sleep behavior disorder. Current opinion in neurobiology. vol 23. issue 5. 2014-04-16. PMID:23518139. |
rbd can precede the onset of pd by decades, suggesting an underlying pathology that can progressively afflict rem atonia and midbrain dopaminergic centers. |
2014-04-16 |
2023-08-12 |
Not clear |
| Reza Sedaghat, Mehrdad Roghani, Mohsen Khalil. Neuroprotective effect of thymoquinone, the nigella sativa bioactive compound, in 6-hydroxydopamine-induced hemi-parkinsonian rat model. Iranian journal of pharmaceutical research : IJPR. vol 13. issue 1. 2014-04-15. PMID:24734075. |
parkinson disease (pd) is the most common movement disorder with progressive degeneration of midbrain dopaminergic neurons for which current treatments afford symptomatic relief with no-prevention of disease progression. |
2014-04-15 |
2023-08-13 |
rat |
| Laura E Been, Nancy A Staffend, Avery Tucker, Robert L Meise. Vesicular glutamate transporter 2 and tyrosine hydroxylase are not co-localized in Syrian hamster nucleus accumbens afferents. Neuroscience letters. vol 550. 2014-04-11. PMID:23850605. |
afferents to the nac can be divided into two anatomically segregated neurochemical phenotypes: dopaminergic inputs, primarily from the midbrain ventral tegmental area (vta) and glutamatergic inputs from several cortical and sub-cortical structures. |
2014-04-11 |
2023-08-12 |
mouse |
| Tae Eun Kim, Ji-Seon Seo, Ji Sun Seo, Jae Won Yang, Min Woong Kim, Rukhsana Kausar, Eunhye Joe, Bo Yeon Kim, Myung Ae Le. Nurr1 represses tyrosine hydroxylase expression via SIRT1 in human neural stem cells. PloS one. vol 8. issue 8. 2014-04-08. PMID:23977047. |
nurr1 is an orphan nuclear receptor best known for its essential role in the development and maintenance of midbrain dopaminergic (da) neurons. |
2014-04-08 |
2023-08-12 |
human |
| Rumana Chowdhury, Marc Guitart-Masip, Christian Lambert, Raymond J Dolan, Emrah Düze. Structural integrity of the substantia nigra and subthalamic nucleus predicts flexibility of instrumental learning in older-age individuals. Neurobiology of aging. vol 34. issue 10. 2014-03-25. PMID:23623600. |
the precise contribution of dopaminergic midbrain regions (substantia nigra/ventral tegmental area [sn/vta]) to this form of behavioral adaptation remains unclear. |
2014-03-25 |
2023-08-12 |
human |
| E M Müller-Oehring, Y-C Jung, E V Sullivan, W C Hawkes, A Pfefferbaum, T Schult. Midbrain-driven emotion and reward processing in alcoholism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 10. 2014-03-24. PMID:23615665. |
enhanced midbrain activation to alcohol-related words suggests neuroadaptation of dopaminergic midbrain systems. |
2014-03-24 |
2023-08-12 |
Not clear |
| Hamzeh Pasban-Aliabadi, Saeed Esmaeili-Mahani, Vahid Sheibani, Mehdi Abbasnejad, Anahita Mehdizadeh, Mohammad Mehdi Yaghoob. Inhibition of 6-hydroxydopamine-induced PC12 cell apoptosis by olive (Olea europaea L.) leaf extract is performed by its main component oleuropein. Rejuvenation research. vol 16. issue 2. 2014-03-21. PMID:23394606. |
parkinson disease (pd) is the most common progressive neurodegenerative disorder characterized by progressive death of midbrain dopaminergic neurons. |
2014-03-21 |
2023-08-12 |
rat |
| Janice M Beit. Parkinson's disease: a review. Frontiers in bioscience (Scholar edition). vol 6. 2014-03-21. PMID:24389262. |
resulting from a pathophysiologic loss or degeneration of dopaminergic neurons in the substantia nigra of the midbrain and the development of neuronal lewy bodies, idiopathic parkinson's disease is associated with risk factors including aging, family history, pesticide exposure and environmental chemicals (e.g., synthetic heroin use). |
2014-03-21 |
2023-08-12 |
Not clear |
| Coraline D Metzger, Martin Walter, Heiko Graf, Birgit Able. SSRI-related modulation of sexual functioning is predicted by pre-treatment resting state functional connectivity in healthy men. Archives of sexual behavior. vol 42. issue 6. 2014-03-20. PMID:23771550. |
data from a 10 min eyes-closed resting state scan were used to analyze functional connectivity under placebo in previously identified brain regions, focussing on the sublenticular extended amygdala (slea), dopaminergic midbrain, and anterior cingulate cortex. |
2014-03-20 |
2023-08-12 |
human |
| Rumana Chowdhury, Christian Lambert, Raymond J Dolan, Emrah Düze. Parcellation of the human substantia nigra based on anatomical connectivity to the striatum. NeuroImage. vol 81. 2014-03-17. PMID:23684858. |
we show that tractography can be used to parcellate the sn/vta into anatomically plausible and behaviourally meaningful compartments, an approach that may help future studies to provide a more fine-grained synopsis of pathological changes in the dopaminergic midbrain and their functional impact. |
2014-03-17 |
2023-08-12 |
human |
| Li-Li Sun, Yan Zhang, Jian-feng Liu, Jun Wang, Wei-li Zhu, Li-yan Zhao, Yan-xue Xue, Lin Lu, Jie Sh. Role of melanin-concentrating hormone in the nucleus accumbens shell in rats behaviourally sensitized to methamphetamine. The international journal of neuropsychopharmacology. vol 16. issue 8. 2014-03-14. PMID:23449013. |
mch has been suggested to regulate the rewarding and reinforcing effects of psychostimulants by potentiating the dopaminergic system within the midbrain. |
2014-03-14 |
2023-08-12 |
rat |
| Einat Nissim-Eliraz, Sophie Zisman, Omri Schatz, Nissim Ben-Ari. Nato3 integrates with the Shh-Foxa2 transcriptional network regulating the differentiation of midbrain dopaminergic neurons. Journal of molecular neuroscience : MN. vol 51. issue 1. 2014-03-12. PMID:23254923. |
nato3 integrates with the shh-foxa2 transcriptional network regulating the differentiation of midbrain dopaminergic neurons. |
2014-03-12 |
2023-08-12 |
Not clear |
| Einat Nissim-Eliraz, Sophie Zisman, Omri Schatz, Nissim Ben-Ari. Nato3 integrates with the Shh-Foxa2 transcriptional network regulating the differentiation of midbrain dopaminergic neurons. Journal of molecular neuroscience : MN. vol 51. issue 1. 2014-03-12. PMID:23254923. |
mesencephalic dopaminergic (mesda) neurons originate from the floor plate of the midbrain, a transient embryonic organizing center located at the ventral-most midline. |
2014-03-12 |
2023-08-12 |
Not clear |