| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jonathan M Lovell, Judith Mylius, Henning Scheich, Michael Brosc. Hearing in action; auditory properties of neurons in the red nucleus of alert primates. Frontiers in neuroscience. vol 8. 2014-05-26. PMID:24860417. |
the response of neurons in the red nucleus pars magnocellularis (rnm) to both tone bursts and electrical stimulation were observed in three cynomolgus monkeys (macaca fascicularis), in a series of studies primarily designed to characterize the influence of the dopaminergic ventral midbrain on auditory processing. |
2014-05-26 |
2023-08-13 |
monkey |
| Linghai Yang, Merle L Gilbert, Ruimao Zheng, G Stanley McKnigh. Selective expression of a dominant-negative type Iα PKA regulatory subunit in striatal medium spiny neurons impairs gene expression and leads to reduced feeding and locomotor activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 14. 2014-05-22. PMID:24695708. |
dopaminergic inputs from the midbrain modulate msn excitability through pathways that involve camp and protein kinase a (pka), but the physiological role of specific pka isoforms in msn neurons remains poorly understood. |
2014-05-22 |
2023-08-13 |
mouse |
| María Eugenia Pallarés, Carlos Javier Baier, Ezequiela Adrover, Melisa Carolina Monteleone, Marcela Adriana Brocco, Marta Cristina Antonell. Age-dependent effects of prenatal stress on the corticolimbic dopaminergic system development in the rat male offspring. Neurochemical research. vol 38. issue 11. 2014-05-21. PMID:24013886. |
we have previously demonstrated that prenatal stress (ps) exerts an impairment of midbrain dopaminergic (da) system metabolism especially after puberty, suggesting a particular sensitivity of da development to variations in gonadal hormonal peaks. |
2014-05-21 |
2023-08-12 |
rat |
| Daniel Dautan, Icnelia Huerta-Ocampo, Ilana B Witten, Karl Deisseroth, J Paul Bolam, Todor Gerdjikov, Juan Mena-Segovi. A major external source of cholinergic innervation of the striatum and nucleus accumbens originates in the brainstem. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 13. 2014-05-19. PMID:24671996. |
furthermore, transynaptic gene activation and conventional double retrograde labeling suggest that ldt neurons that innervate the nucleus accumbens also send collaterals to the thalamus and the dopaminergic midbrain, thus providing both direct and indirect projections, to the striatal complex. |
2014-05-19 |
2023-08-12 |
rat |
| Ruben K Dagda, Irene Pien, Ruth Wang, Jianhui Zhu, Kent Z Q Wang, Jason Callio, Tania Das Banerjee, Raul Y Dagda, Charleen T Ch. Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through protein kinase A. Journal of neurochemistry. vol 128. issue 6. 2014-05-14. PMID:24151868. |
over-expression of wild-type pink1, but not a catalytically inactive form of pink1(k219m), promoted neurite outgrowth in sh-sy5y cells and increased dendritic lengths in primary cortical and midbrain dopaminergic neurons. |
2014-05-14 |
2023-08-12 |
Not clear |
| Gina Lungu, George Stoica, Andy Ambru. MicroRNA profiling and the role of microRNA-132 in neurodegeneration using a rat model. Neuroscience letters. vol 553. 2014-05-08. PMID:23973300. |
next we analyzed one of the known downstream targets of mir-132, nuclear receptor related 1 protein (nurr1), which is essential in neurogenesis of midbrain dopaminergic neurons. |
2014-05-08 |
2023-08-12 |
rat |
| Gina Lungu, George Stoica, Andy Ambru. MicroRNA profiling and the role of microRNA-132 in neurodegeneration using a rat model. Neuroscience letters. vol 553. 2014-05-08. PMID:23973300. |
taken together, our findings suggest that mir-132 can regulate nurr1 levels and might influence the development and function of midbrain dopaminergic neurons. |
2014-05-08 |
2023-08-12 |
rat |
| Andreas Hermann, Kai F Loewenbrück, Änne Boldt, Christiane Fiedler, Martina Maisel, Joanna Kalucka, Johannes Schwarz, Georg Breier, Alexander Storc. Lack of vascular endothelial growth factor receptor-2/Flk1 signaling does not affect substantia nigra development. Neuroscience letters. vol 553. 2014-05-08. PMID:23994060. |
lack of hypoxia-inducible factor-1α (hif1α) impairs midbrain dopaminergic neurogenesis which could be rescued by vascular endothelial growth factor (vegf) via vegfr-2 signaling. |
2014-05-08 |
2023-08-12 |
mouse |
| Shujie Wang, Yan Tan, Ju-En Zhang, Minmin Lu. Pharmacogenetic activation of midbrain dopaminergic neurons induces hyperactivity. Neuroscience bulletin. vol 29. issue 5. 2014-05-02. PMID:23516143. |
pharmacogenetic activation of midbrain dopaminergic neurons induces hyperactivity. |
2014-05-02 |
2023-08-12 |
mouse |
| Shujie Wang, Yan Tan, Ju-En Zhang, Minmin Lu. Pharmacogenetic activation of midbrain dopaminergic neurons induces hyperactivity. Neuroscience bulletin. vol 29. issue 5. 2014-05-02. PMID:23516143. |
the results showed that cno selectively activated midbrain dopaminergic neurons and induced hyperactivity in a dose-dependent manner, supporting the idea that these neurons play an important role in regulating motor activity. |
2014-05-02 |
2023-08-12 |
mouse |
| William Omar Contreras Lopez, Guido Nikkhah, Ulf D Kahlert, Donata Maciaczyk, Tomasz Bogiel, Sven Moellers, Elisabeth Schültke, Máté Döbrössy, Jaroslaw Maciaczy. Clinical neurotransplantation protocol for Huntington's and Parkinson's disease. Restorative neurology and neuroscience. vol 31. issue 5. 2014-04-22. PMID:23777636. |
the concept of transplantation of neuronal cells to treat huntington's and parkinson's diseases is based on the proven principle that dopaminergic and gaba-ergic progenitor neurons (from the human developing ventral mesencephalon and whole ganglionic eminence) can survive, differentiate and functionally integrate into an allogenic host brain. |
2014-04-22 |
2023-08-12 |
human |
| Daniel J Foster, Patrick R Gentry, Jose E Lizardi-Ortiz, Thomas M Bridges, Michael R Wood, Colleen M Niswender, David Sulzer, Craig W Lindsley, Zixiu Xiang, P Jeffrey Con. M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 9. 2014-04-22. PMID:24573284. |
of the five muscarinic receptor subtypes, the m5 receptor is the only one detectable in midbrain dopaminergic neurons, making it an attractive potential therapeutic target for treating disorders in which dopaminergic signaling is disrupted. |
2014-04-22 |
2023-08-12 |
mouse |
| Victoria B Gradin, Gordon Waiter, Akira O'Connor, Liana Romaniuk, Catriona Stickle, Keith Matthews, Jeremy Hall, J Douglas Steel. Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia. Psychiatry research. vol 211. issue 2. 2014-04-21. PMID:23146249. |
furthermore, we investigated functional connectivity between the dopaminergic midbrain, a key region for the processing of reinforcers, and other brain regions. |
2014-04-21 |
2023-08-12 |
Not clear |
| M A Fahim, S Shehab, A Nemmar, A Adem, S Dhanasekaran, M Y Hasa. Daily subacute paraquat exposure decreases muscle function and substantia nigra dopamine level. Physiological research. vol 62. issue 3. 2014-04-21. PMID:23489189. |
dopamine concentrations in the ventral mesencephalon were measured by high performance liquid chromatography and the number of dopaminergic neurons in substantia nigra pars compacta was estimated by tyrosine hydroxylase immunohistochemistry. |
2014-04-21 |
2023-08-12 |
rat |
| Michael C Chen, Huan Yu, Zhi-Li Huang, Jun L. Rapid eye movement sleep behavior disorder. Current opinion in neurobiology. vol 23. issue 5. 2014-04-16. PMID:23518139. |
rbd can precede the onset of pd by decades, suggesting an underlying pathology that can progressively afflict rem atonia and midbrain dopaminergic centers. |
2014-04-16 |
2023-08-12 |
Not clear |
| Reza Sedaghat, Mehrdad Roghani, Mohsen Khalil. Neuroprotective effect of thymoquinone, the nigella sativa bioactive compound, in 6-hydroxydopamine-induced hemi-parkinsonian rat model. Iranian journal of pharmaceutical research : IJPR. vol 13. issue 1. 2014-04-15. PMID:24734075. |
parkinson disease (pd) is the most common movement disorder with progressive degeneration of midbrain dopaminergic neurons for which current treatments afford symptomatic relief with no-prevention of disease progression. |
2014-04-15 |
2023-08-13 |
rat |
| Laura E Been, Nancy A Staffend, Avery Tucker, Robert L Meise. Vesicular glutamate transporter 2 and tyrosine hydroxylase are not co-localized in Syrian hamster nucleus accumbens afferents. Neuroscience letters. vol 550. 2014-04-11. PMID:23850605. |
afferents to the nac can be divided into two anatomically segregated neurochemical phenotypes: dopaminergic inputs, primarily from the midbrain ventral tegmental area (vta) and glutamatergic inputs from several cortical and sub-cortical structures. |
2014-04-11 |
2023-08-12 |
mouse |
| Tae Eun Kim, Ji-Seon Seo, Ji Sun Seo, Jae Won Yang, Min Woong Kim, Rukhsana Kausar, Eunhye Joe, Bo Yeon Kim, Myung Ae Le. Nurr1 represses tyrosine hydroxylase expression via SIRT1 in human neural stem cells. PloS one. vol 8. issue 8. 2014-04-08. PMID:23977047. |
nurr1 is an orphan nuclear receptor best known for its essential role in the development and maintenance of midbrain dopaminergic (da) neurons. |
2014-04-08 |
2023-08-12 |
human |
| Rumana Chowdhury, Marc Guitart-Masip, Christian Lambert, Raymond J Dolan, Emrah Düze. Structural integrity of the substantia nigra and subthalamic nucleus predicts flexibility of instrumental learning in older-age individuals. Neurobiology of aging. vol 34. issue 10. 2014-03-25. PMID:23623600. |
the precise contribution of dopaminergic midbrain regions (substantia nigra/ventral tegmental area [sn/vta]) to this form of behavioral adaptation remains unclear. |
2014-03-25 |
2023-08-12 |
human |
| E M Müller-Oehring, Y-C Jung, E V Sullivan, W C Hawkes, A Pfefferbaum, T Schult. Midbrain-driven emotion and reward processing in alcoholism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 10. 2014-03-24. PMID:23615665. |
enhanced midbrain activation to alcohol-related words suggests neuroadaptation of dopaminergic midbrain systems. |
2014-03-24 |
2023-08-12 |
Not clear |