| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Henriqueta Dias Cardoso, Eraldo Fonseca dos Santos Junior, David Filipe de Santana, Catarina Gonçalves-Pimentel, Monara Kaélle Angelim, Alinny R Isaac, Cláudia Jacques Lagranha, Rubem Carlos Araújo Guedes, Eduardo Isidoro Beltrão, Edgar Morya, Marcelo Cairrão Araújo Rodrigues, Belmira Lara da Silveira Andrade-da-Cost. Omega-3 deficiency and neurodegeneration in the substantia nigra: involvement of increased nitric oxide production and reduced BDNF expression. Biochimica et biophysica acta. vol 1840. issue 6. 2014-07-03. PMID:24361617. |
our previous study demonstrated that essential fatty acid (efa) dietary restriction over two generations induced midbrain dopaminergic cell loss and oxidative stress in the substantia nigra (sn) but not in the striatum of young rats. |
2014-07-03 |
2023-08-12 |
rat |
| James Sulzer, Ranganatha Sitaram, Maria Laura Blefari, Spyros Kollias, Niels Birbaumer, Klaas Enno Stephan, Andreas Luft, Roger Gasser. Neurofeedback-mediated self-regulation of the dopaminergic midbrain. NeuroImage. vol 83. 2014-06-25. PMID:23791838. |
neurofeedback-mediated self-regulation of the dopaminergic midbrain. |
2014-06-25 |
2023-08-12 |
human |
| Krystyna Gołembiowska, Klemencja Berghauzen-Maciejewska, Anna Górska, Katarzyna Kamińska, Krystyna Ossowsk. A partial lesion of the substantia nigra pars compacta and retrorubral field decreases the harmaline-induced glutamate release in the rat cerebellum. Brain research. vol 1537. 2014-06-25. PMID:24012623. |
the results of the present study seem to indicate that midbrain dopaminergic neurons influence glutamatergic transmission in the cerebellum which may be important for generation of the tremor induced by harmaline. |
2014-06-25 |
2023-08-12 |
rat |
| Tandis Vazin, Randolph S Ashton, Anthony Conway, Nikhil A Rode, Susan M Lee, Verenice Bravo, Kevin E Healy, Ravi S Kane, David V Schaffe. The effect of multivalent Sonic hedgehog on differentiation of human embryonic stem cells into dopaminergic and GABAergic neurons. Biomaterials. vol 35. issue 3. 2014-06-25. PMID:24172856. |
among its many activities, shh is required for ventralization of the midbrain and forebrain and is therefore critical for the development of midbrain dopaminergic (mda) and forebrain gamma-aminobutyric acid (gaba) inhibitory neurons. |
2014-06-25 |
2023-08-12 |
human |
| Sabrina M Heman-Ackah, Martina Hallegger, Mahendra S Rao, Matthew J A Woo. RISC in PD: the impact of microRNAs in Parkinson's disease cellular and molecular pathogenesis. Frontiers in molecular neuroscience. vol 6. 2014-06-24. PMID:24312000. |
parkinson's disease (pd) is a debilitating neurodegenerative disease characterized primarily by the selective death of dopaminergic (da) neurons in the substantia nigra pars compacta of the midbrain. |
2014-06-24 |
2023-08-12 |
Not clear |
| Zhifang Qiu, Steven L Farnsworth, Anuja Mishra, Peter J Hornsb. Patient-specific induced pluripotent stem cells in neurological disease modeling: the importance of nonhuman primate models. Stem cells and cloning : advances and applications. vol 6. 2014-06-24. PMID:24426786. |
these developments have resulted in the ability to produce large numbers of dopaminergic neurons with midbrain characteristics for further study. |
2014-06-24 |
2023-08-12 |
human |
| Hongwon Kim, Xiaoyuan Quan, Yeju Seong, Jongpil Ki. Impaired motor coordination in Pitx3 overexpression mice. Biochemical and biophysical research communications. vol 446. issue 4. 2014-06-24. PMID:24680684. |
midbrain dopaminergic (da) neurons are involved in the regulation of voluntary movement and in emotion-related behaviors and are affected in parkinson's disease (pd). |
2014-06-24 |
2023-08-12 |
mouse |
| Simon D Fisher, John N J Reynold. The intralaminar thalamus-an expressway linking visual stimuli to circuits determining agency and action selection. Frontiers in behavioral neuroscience. vol 8. 2014-06-24. PMID:24765070. |
together with a converging input from the cerebral cortex, and a neuromodulatory dopaminergic input from the midbrain, the components previously found necessary for reinforcement learning in the basal ganglia are present. |
2014-06-24 |
2023-08-13 |
Not clear |
| Genaro Gabriel Ortiz, Fermín P Pacheco-Moisés, Víctor M Gómez-Rodríguez, Erika D González-Renovato, Erandhis D Torres-Sánchez, Ana C Ramírez-Anguian. Fish oil, melatonin and vitamin E attenuates midbrain cyclooxygenase-2 activity and oxidative stress after the administration of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine. Metabolic brain disease. vol 28. issue 4. 2014-06-20. PMID:23703110. |
parkinson's disease is a neurodegenerative disease whose hallmark pathological features include a selective loss of dopaminergic neurons in the midbrain. |
2014-06-20 |
2023-08-12 |
mouse |
| Shane V Hegarty, Aideen M Sullivan, Gerard W O'Keeff. BMP2 and GDF5 induce neuronal differentiation through a Smad dependant pathway in a model of human midbrain dopaminergic neurons. Molecular and cellular neurosciences. vol 56. 2014-06-20. PMID:23831389. |
bmp2 and gdf5 induce neuronal differentiation through a smad dependant pathway in a model of human midbrain dopaminergic neurons. |
2014-06-20 |
2023-08-12 |
human |
| Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Hirotaka Onoe, Takuya Hayashi, Toshiyuki Kawasaki, Hidemoto Saiki, Susumu Miyamoto, Jun Takahash. Survival of human induced pluripotent stem cell-derived midbrain dopaminergic neurons in the brain of a primate model of Parkinson's disease. Journal of Parkinson's disease. vol 1. issue 4. 2014-06-20. PMID:23933658. |
survival of human induced pluripotent stem cell-derived midbrain dopaminergic neurons in the brain of a primate model of parkinson's disease. |
2014-06-20 |
2023-08-12 |
mouse |
| Olof Zachrisson, Ming Zhao, Annica Andersson, Karin Dannaeus, Johan Häggblad, Ruben Isacson, Elisabet Nielsen, Cesare Patrone, Harriet Rönnholm, Lilian Wikstrom, Kristofer Delfani, Alison L McCormack, Theo Palmer, Donato A Di Monte, Michael P Hill, Ann Marie Janson Lang, Anders Haegerstran. Restorative effects of platelet derived growth factor-BB in rodent models of Parkinson's disease. Journal of Parkinson's disease. vol 1. issue 1. 2014-06-18. PMID:23939256. |
parkinson's disease is characterized by motor deficits caused by loss of midbrain dopaminergic neurons. |
2014-06-18 |
2023-08-12 |
rat |
| Maria Sundberg, Helle Bogetofte, Tristan Lawson, Johan Jansson, Gaynor Smith, Arnar Astradsson, Michele Moore, Teresia Osborn, Oliver Cooper, Roger Spealman, Penelope Hallett, Ole Isacso. Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons. Stem cells (Dayton, Ohio). vol 31. issue 8. 2014-06-15. PMID:23666606. |
the main motor symptoms of parkinson's disease are due to the loss of dopaminergic (da) neurons in the ventral midbrain (vm). |
2014-06-15 |
2023-08-12 |
human |
| Claudia M García-Peña, Minkyung Kim, Daniela Frade-Pérez, Daniela Avila-González, Elisa Téllez, Grant S Mastick, Elisa Tamariz, Alfredo Varela-Echavarrí. Ascending midbrain dopaminergic axons require descending GAD65 axon fascicles for normal pathfinding. Frontiers in neuroanatomy. vol 8. 2014-06-13. PMID:24926237. |
ascending midbrain dopaminergic axons require descending gad65 axon fascicles for normal pathfinding. |
2014-06-13 |
2023-08-13 |
mouse |
| Claudia M García-Peña, Minkyung Kim, Daniela Frade-Pérez, Daniela Avila-González, Elisa Téllez, Grant S Mastick, Elisa Tamariz, Alfredo Varela-Echavarrí. Ascending midbrain dopaminergic axons require descending GAD65 axon fascicles for normal pathfinding. Frontiers in neuroanatomy. vol 8. 2014-06-13. PMID:24926237. |
the nigrostriatal pathway (nsp) is formed by dopaminergic axons that project from the ventral midbrain to the dorsolateral striatum as part of the medial forebrain bundle. |
2014-06-13 |
2023-08-13 |
mouse |
| Claudia M García-Peña, Minkyung Kim, Daniela Frade-Pérez, Daniela Avila-González, Elisa Téllez, Grant S Mastick, Elisa Tamariz, Alfredo Varela-Echavarrí. Ascending midbrain dopaminergic axons require descending GAD65 axon fascicles for normal pathfinding. Frontiers in neuroanatomy. vol 8. 2014-06-13. PMID:24926237. |
we observed in mouse and rat embryos that midbrain dopaminergic axons ascend in close apposition to descending gad65-positive axon bundles throughout their trajectory to the striatum. |
2014-06-13 |
2023-08-13 |
mouse |
| Xiaofeng Xu, Naidong Wang, Huamin Xu, Anmu Xie, Hong Jiang, Junxia Xi. Fibroblast growth factor 20 polymorphism in sporadic Parkinson's disease in Northern Han Chinese. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 20. issue 11. 2014-06-06. PMID:23938014. |
fibroblast growth factor (fgf) 20 is a neurotrophic factor that exerts strong neurotrophic properties in the brain and could significantly enhance the survival of rat midbrain dopaminergic neurons. |
2014-06-06 |
2023-08-12 |
rat |
| Rami R Ajjuri, Janis M O'Donnel. Novel whole-tissue quantitative assay of nitric oxide levels in Drosophila neuroinflammatory response. Journal of visualized experiments : JoVE. issue 82. 2014-06-05. PMID:24335747. |
for example, loss of dopaminergic neurons in the midbrain, a hallmark of pd, is accelerated by the excessive activation of the inflammatory response. |
2014-06-05 |
2023-08-12 |
drosophila_melanogaster |
| Anke Zlotnik, Björn Spitta. GDNF fails to inhibit LPS-mediated activation of mouse microglia. Journal of neuroimmunology. vol 270. issue 1-2. 2014-06-05. PMID:24655425. |
gdnf is a potent neuroprotective factor for midbrain dopaminergic (mda) neurons. |
2014-06-05 |
2023-08-12 |
mouse |
| Kazuto Kobayashi, Ryoji Fukabori, Kayo Nishizaw. Neural circuit mechanism for learning dependent on dopamine transmission: roles of striatal direct and indirect pathways in sensory discrimination. Advances in pharmacology (San Diego, Calif.). vol 68. 2014-05-29. PMID:24054143. |
the striatum receives excitatory inputs from many cortical areas and the thalamic nuclei and dopaminergic inputs from the ventral midbrain and projects to the output nuclei through direct and indirect pathways. |
2014-05-29 |
2023-08-12 |
mouse |