| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shashank Vasudevan, Andrea Dotti, Janko Kajtez, Alberto Martínez-Serrano, Carsten Gundlach, Sandrina Campos Maçãs, Karin Lauschke, Anne-Marie Vinngaard, Silvia García López, Marta Pereira, Arto Heiskanen, Stephan S Keller, Jenny Emnéu. Omnidirectional leaky opto-electrical fiber for optogenetic control of neurons in cell replacement therapy. Bioelectrochemistry (Amsterdam, Netherlands). vol 149. 2022-11-08. PMID:36345111. |
the pathophysiological progress of parkinson's disease leads through degeneration of dopaminergic neurons in the substantia nigra to complete cell death and lack of dopamine in the striatum where it modulates motor functions. |
2022-11-08 |
2023-08-14 |
Not clear |
| Shashank Vasudevan, Andrea Dotti, Janko Kajtez, Alberto Martínez-Serrano, Carsten Gundlach, Sandrina Campos Maçãs, Karin Lauschke, Anne-Marie Vinngaard, Silvia García López, Marta Pereira, Arto Heiskanen, Stephan S Keller, Jenny Emnéu. Omnidirectional leaky opto-electrical fiber for optogenetic control of neurons in cell replacement therapy. Bioelectrochemistry (Amsterdam, Netherlands). vol 149. 2022-11-08. PMID:36345111. |
transplantation of dopaminergic stem cell-derived neurons is a possible therapy to restore dopamine levels. |
2022-11-08 |
2023-08-14 |
Not clear |
| Laísa Aliandro Dos Santos, Gabriela Salles Dos Santos, Gustavo Ariel Borges Fernandes, Michelle Fidelis Corrêa, Carolina Aparecida de Faria Almeida, Liliam Fernandes, Tania Marcourakis, João Paulo S Fernandes, Raphael Caio Tamborelli Garci. Neurotoxicity Assessment of 1-[(2,3-Dihydro-1-Benzofuran-2-yl)Methyl]Piperazine (LINS01 Series) Derivatives and their Protective Effect on Cocaine-Induced Neurotoxicity Model in SH-SY5Y Cell Culture. Neurotoxicity research. 2022-11-07. PMID:36342586. |
excessive levels of dopamine in the synaptic cleft, induced by cocaine for example, activates dopaminergic receptors, mainly d |
2022-11-07 |
2023-08-14 |
Not clear |
| Yingliang Xie, Peizhen Wang, Xiaoyan Cui, Lei Liu, Pengcheng Wang, Shimei Jing, Qi Liu, Yuting Wang, Shiqiang Wan. Retraction notice to "Dopaminergic neurons project to the nucleus accumbens regulates anxiety-like behaviors through dopamine D Behavioural brain research. vol 438. 2022-11-06. PMID:36335880. |
retraction notice to "dopaminergic neurons project to the nucleus accumbens regulates anxiety-like behaviors through dopamine d |
2022-11-06 |
2023-08-14 |
Not clear |
| Shima Tavakol, Elham Hoveizi, Hani Tavakol, Amin Almasi, Mansoureh Soleimani, Shadi Rabiee Motmaen, Fereshteh Azedi, Mohammad Taghi Joghatae. Strong binding of phytochemicals to the catalytic domain of tyrosine hydroxylase as a Trojan horse decreases dopamine in dopaminergic cells: Pharmaceutical considerations in schizophrenia and Parkinson's disease. Current pharmaceutical design. 2022-11-04. PMID:36330626. |
strong binding of phytochemicals to the catalytic domain of tyrosine hydroxylase as a trojan horse decreases dopamine in dopaminergic cells: pharmaceutical considerations in schizophrenia and parkinson's disease. |
2022-11-04 |
2023-08-14 |
Not clear |
| Ichiro Kawahata, Kohji Fukunag. [Development of therapeutic peptides for Lewy body diseases preventing α-synuclein propagation]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 157. issue 6. 2022-11-03. PMID:36328546. |
type 3 fatty acid-binding protein (fabp3) is highly expressed in dopaminergic neurons and has the ability to bind dopamine receptors, particularly dopamine d2 long type (d2l) receptors, which are abundantly localized on caveolae structures in the plasma membrane. |
2022-11-03 |
2023-08-14 |
mouse |
| Lakshmi N Yatham, Peter F Liddle, Marjorie Gonzalez, Gayatri Saraf, Nasim Vafai, Raymond W Lam, Vesna Soss. A Positron Emission Tomography Study of Dopamine Transporter Density in Patients With Bipolar Disorder With Current Mania and Those With Recently Remitted Mania. JAMA psychiatry. 2022-11-02. PMID:36322065. |
although dopamine is implicated in the pathophysiology of bipolar disorder (bd), the precise alterations in the dopaminergic system remain unknown. |
2022-11-02 |
2023-08-14 |
Not clear |
| Eva M Szego, Laura Malz, Nadine Bernhardt, Angela Rösen-Wolff, Björn H Falkenburger, Hella Luksc. Constitutively active STING causes neuroinflammation and degeneration of dopaminergic neurons in mice. eLife. vol 11. 2022-10-31. PMID:36314770. |
in adult mice expressing n153s sting, the number of dopaminergic neurons was smaller than in controls, as was the density of dopaminergic axon terminals and the concentration of dopamine in the striatum. |
2022-10-31 |
2023-08-14 |
mouse |
| Marit F L Ruitenberg, Elger L Abrahamse, Patrick Santens, Wim Notebaer. Testing the dopamine overdose hypothesis in action control: A study in people with Parkinson's disease. Journal of neuropsychology. 2022-10-28. PMID:36303524. |
our findings do not support the notion that dopaminergic medication modulates action control processes, suggesting that the dopamine overdose hypothesis may only apply to a specific set of cognitive processes and should potentially be refined. |
2022-10-28 |
2023-08-14 |
Not clear |
| Sara Abidar, Lucian Hritcu, Mohamed Nhir. The Natural Neuroprotective Compounds Used in the 6-Hydroxydopamine-Induced Parkinson's Disease in Zebrafish: The Current Applications and Perspectives. CNS & neurological disorders drug targets. 2022-10-28. PMID:36306449. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by the degeneration of the dopaminergic neurons in the substantia nigra pars compacta, resulting in the loss of dopamine in the striatum, leading thus to the pd classic movement symptoms: resting tremor, rigidity, and bradykinesia/akinesia. |
2022-10-28 |
2023-08-14 |
zebrafish |
| Meng Ning, Shizhe Wen, Peiling Zhou, Changzheng Zhan. Ventral tegmental area dopaminergic action in music therapy for post-traumatic stress disorder: A literature review. Frontiers in psychology. vol 13. 2022-10-27. PMID:36300072. |
in this literature review, we focused on whether music improved ptsd symptoms, based on vta dopaminergic action, including the effects of music on dopamine (da)-related gene expression, the promotion of da release and metabolism, and the activation of vta functional activities. |
2022-10-27 |
2023-08-14 |
Not clear |
| Jing Deng, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zhen. Gender differences in cocaine-induced hyperactivity and dopamine transporter trafficking to the plasma membrane. Addiction biology. vol 27. issue 6. 2022-10-27. PMID:36301205. |
as well known, cocaine induces stimulant effects and dopamine transporter (dat) trafficking to the plasma membrane of dopaminergic neurons. |
2022-10-27 |
2023-08-14 |
rat |
| Ermanno Florio, Marcello Serra, Robert G Lewis, Enikö Kramár, Michael Freidberg, Marcello Wood, Micaela Morelli, Emiliana Borrell. D2R signaling in striatal spiny neurons modulates L-DOPA induced dyskinesia. iScience. vol 25. issue 10. 2022-10-24. PMID:36274959. |
degeneration of dopaminergic neurons leads to parkinson's disease (pd), characterized by reduced levels of striatal dopamine (da) and impaired voluntary movements. |
2022-10-24 |
2023-08-14 |
Not clear |
| Laura Scott, Senthilkumar S Karuppagounder, Stewart Neifert, Bong Gu Kang, Hu Wang, Valina L Dawson, Ted M Dawso. The absence of Parkin does not promote dopamine or mitochondrial dysfunction in PolgA The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-10-24. PMID:36280265. |
the absence of parkin does not promote dopamine or mitochondrial dysfunction in polga parkinson's disease (pd) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. |
2022-10-24 |
2023-08-14 |
Not clear |
| Kristina Sabaroedin, Jeggan Tiego, Alex Fornit. Circuit-Based Approaches to Understanding Corticostriatothalamic Dysfunction Across the Psychosis Continuum. Biological psychiatry. 2022-10-17. PMID:36253195. |
dopamine is known to play a role in the pathogenesis of psychotic symptoms, but the mechanisms driving dopaminergic dysfunction in psychosis remain unclear. |
2022-10-17 |
2023-08-14 |
human |
| Dmitry Troshev, Alyona Bannikova, Victor Blokhin, Anna Kolacheva, Tatiana Pronina, Michael Ugrumo. Striatal Neurons Partially Expressing a Dopaminergic Phenotype: Functional Significance and Regulation. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232359. |
in this study, it was shown that in transgenic mice expressing green fluorescent protein (gfp) under the tyrosine hydroxylase (th) gene promoter, (i) there are striatal neurons expressing only th, only aromatic l-amino acid decarboxylase (aadc), or both enzymes of dopamine synthesis; (ii) striatal neurons expressing dopamine-synthesizing enzymes are not dopaminergic since they lack a dopamine transporter; (iii) monoenzymatic neurons expressing individual complementary dopamine-synthesizing enzymes produce this neurotransmitter in cooperation; (iv) striatal nerve fibers containing only th, only aadc, or both enzymes project into the lateral ventricles, providing delivery pathways for l-3,4-dihydroxyphenylalanine and dopamine to the cerebrospinal fluid; and (v) striatal gfp neurons express receptor genes for various signaling molecules, i.e., classical neurotransmitters, neuropeptides, and steroids, indicating fine regulation of these neurons. |
2022-10-14 |
2023-08-14 |
mouse |
| Dmitry Troshev, Alyona Bannikova, Victor Blokhin, Anna Kolacheva, Tatiana Pronina, Michael Ugrumo. Striatal Neurons Partially Expressing a Dopaminergic Phenotype: Functional Significance and Regulation. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232359. |
based on our data, it is assumed that the synthesis of dopamine by striatal neurons is a compensatory response to the death of nigral dopaminergic neurons in parkinson's disease, which opens broad prospects for the development of a fundamentally novel antiparkinsonian therapy. |
2022-10-14 |
2023-08-14 |
mouse |
| Xinjian Zhang, Daisuke Tsuboi, Yasuhiro Funahashi, Yukie Yamahashi, Kozo Kaibuchi, Taku Naga. Phosphorylation Signals Downstream of Dopamine Receptors in Emotional Behaviors: Association with Preference and Avoidance. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232945. |
dopamine regulates emotional behaviors, including rewarding and aversive behaviors, through the mesolimbic dopaminergic pathway, which projects dopamine neurons from the ventral tegmental area to the nucleus accumbens (nac). |
2022-10-14 |
2023-08-14 |
Not clear |
| Allen P F Chen, Jeffrey M Malgady, Lu Chen, Kaiyo W Shi, Eileen Cheng, Joshua L Plotkin, Shaoyu Ge, Qiaojie Xion. Nigrostriatal dopamine pathway regulates auditory discrimination behavior. Nature communications. vol 13. issue 1. 2022-10-08. PMID:36209150. |
in vivo dopamine and calcium imaging in freely behaving mice revealed that this dopaminergic projection modulates striatal tone representations, and tone-evoked striatal dopamine release inversely correlated with the evidence strength of tones. |
2022-10-08 |
2023-08-14 |
mouse |
| Paweł Napora, Anna Kobrzycka, Krystyna Pierzchała-Koziec, Marek Wieczore. Effect of Selective Cyclooxygenase Inhibitors on Animal Behaviour and Monoaminergic Systems of the Rat Brain. Behavioural brain research. 2022-10-07. PMID:36206821. |
we suggest that the effect of used inhibitors on the dopaminergic system is associated with a possible increase in anandamide concentration and its effect on dopamine reuptake in synaptic clefts. |
2022-10-07 |
2023-08-14 |
rat |