| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuai Wang, Ming Li, Linlan Su, Yu Wang, Dongliang Ma, Hongyan Wang, Jie Zhu, Teng Che. Knockout of Dopamine D3 Receptor Gene Blocked Methamphetamine-Induced Distinct Changes of Dopaminergic and Glutamatergic Synapse in the Nucleus Accumbens Shell of Mice. Frontiers in cellular neuroscience. vol 16. 2022-06-17. PMID:35711471. |
however, the distinct changes of dopaminergic and glutamatergic synapses and the modulating effects of dopamine d3 receptor remain unclear. |
2022-06-17 |
2023-08-14 |
mouse |
| Matthew J Reid, Maria Rogdaki, Lucia Dutan, Bjørn Hanger, Kaarin Sabad, Roland Nagy, Dwaipayan Adhya, Simon Baron-Cohen, Grainne McAlonan, Jack Price, Anthony C Vernon, Oliver D Howes, Deepak P Srivastav. Cell line specific alterations in genes associated with dopamine metabolism and signaling in midbrain dopaminergic neurons derived from 22q11.2 deletion carriers with elevated dopamine synthesis capacity. Schizophrenia research. 2022-06-14. PMID:35701280. |
cell line specific alterations in genes associated with dopamine metabolism and signaling in midbrain dopaminergic neurons derived from 22q11.2 deletion carriers with elevated dopamine synthesis capacity. |
2022-06-14 |
2023-08-14 |
Not clear |
| Guillaume Meyer, Clara Gitahy Falcao Faria, Marine Beck, Marielle Riutort, Bruno Michel, Hervé Javelo. Suicidality and psychotic episodes after starting aripiprazole: two case reports. International clinical psychopharmacology. 2022-06-13. PMID:35695655. |
a strong dopamine antagonist may lead to the development of dopaminergic upregulation. |
2022-06-13 |
2023-08-14 |
Not clear |
| Jin Xue, Yingbao Zhu, Liyi Wei, Hongjing Huang, Guangxu Li, Wen Huang, Hua Zhu, Ranhui Dua. Loss of Drosophila NUS1 results in cholesterol accumulation and Parkinson's disease-related neurodegeneration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36. issue 7. 2022-06-13. PMID:35695805. |
in our previous study, it was shown that knockdown of drosophila nus1 orthologous gene tango14 causes decreased climbing ability, loss of dopaminergic neurons, and decreased dopamine contents. |
2022-06-13 |
2023-08-14 |
drosophila_melanogaster |
| Jin Xue, Yingbao Zhu, Liyi Wei, Hongjing Huang, Guangxu Li, Wen Huang, Hua Zhu, Ranhui Dua. Loss of Drosophila NUS1 results in cholesterol accumulation and Parkinson's disease-related neurodegeneration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36. issue 7. 2022-06-13. PMID:35695805. |
in addition, tango14 knockdown increased α-synuclein (α-syn) neurotoxicity in α-syn-overexpressing flies, with decreased locomotive activities, dopamine contents, and the numbers of dopaminergic neurons in aging flies. |
2022-06-13 |
2023-08-14 |
drosophila_melanogaster |
| Vincent Paget-Blanc, Marlene E Pfeffer, Marie Pronot, Paul Lapios, Maria-Florencia Angelo, Roman Walle, Fabrice P Cordelières, Florian Levet, Stéphane Claverol, Sabrina Lacomme, Mélina Petrel, Christelle Martin, Vincent Pitard, Véronique De Smedt Peyrusse, Thomas Biederer, David Perrais, Pierre Trifilieff, Etienne Herzo. A synaptomic analysis reveals dopamine hub synapses in the mouse striatum. Nature communications. vol 13. issue 1. 2022-06-06. PMID:35660742. |
moreover, our data reveal the adhesion of dopaminergic synapses to glutamatergic, gabaergic or cholinergic synapses in structures we named "dopamine hub synapses". |
2022-06-06 |
2023-08-14 |
mouse |
| Vincent Paget-Blanc, Marlene E Pfeffer, Marie Pronot, Paul Lapios, Maria-Florencia Angelo, Roman Walle, Fabrice P Cordelières, Florian Levet, Stéphane Claverol, Sabrina Lacomme, Mélina Petrel, Christelle Martin, Vincent Pitard, Véronique De Smedt Peyrusse, Thomas Biederer, David Perrais, Pierre Trifilieff, Etienne Herzo. A synaptomic analysis reveals dopamine hub synapses in the mouse striatum. Nature communications. vol 13. issue 1. 2022-06-06. PMID:35660742. |
dopamine hub synapses may thus support local dopaminergic signalling, complementing volume transmission thought to be the major mechanism by which monoamines modulate network activity. |
2022-06-06 |
2023-08-14 |
mouse |
| Cláudia M Deus, José Teixeira, Nuno Raimundo, Paolo Tucci, Fernanda Borges, Luciano Saso, Paulo J Oliveir. Modulation of cellular redox environment as a novel therapeutic strategy for Parkinson's Disease. European journal of clinical investigation. 2022-05-31. PMID:35638352. |
pathologically, pd is characterized by dopaminergic cell neurodegeneration in the substantia nigra, resulting in decreased dopamine levels in the nigrostriatal pathway, triggering motor symptoms. |
2022-05-31 |
2023-08-13 |
Not clear |
| Olivier Rampin, Audrey Saint Albin Deliot, Christian Ouali, Jasmine Burguet, Elisa Gry, Gaelle Champeil Potokar, Nathalie Jérôme, Olga Davidenko, Nicolas Darcel, Vincent Bombail, Philippe Andrey, Isabelle Deni. Dopamine Modulates the Processing of Food Odour in the Ventral Striatum. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625863. |
since the ventral striatum, at the crossroads of olfactory and reward pathways, receives a rich dopaminergic innervation, we hypothesized that dopamine plays a role in food odour information processing in the ventral striatum. |
2022-05-28 |
2023-08-13 |
rat |
| Olivier Rampin, Audrey Saint Albin Deliot, Christian Ouali, Jasmine Burguet, Elisa Gry, Gaelle Champeil Potokar, Nathalie Jérôme, Olga Davidenko, Nicolas Darcel, Vincent Bombail, Philippe Andrey, Isabelle Deni. Dopamine Modulates the Processing of Food Odour in the Ventral Striatum. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625863. |
this response was modulated by dopamine, as evidenced by its depression following administration of the dopaminergic d1 and d2 antagonists sch23390 and raclopride. |
2022-05-28 |
2023-08-13 |
rat |
| Kärt Mätlik, Daniel R Garton, Ana R Montaño-Rodríguez, Soophie Olfat, Feride Eren, Laoise Casserly, Anastasios Damdimopoulos, Anne Panhelainen, L Lauriina Porokuokka, Jaakko J Kopra, Giorgio Turconi, Nadine Schweizer, Erika Bereczki, Fredrik Piehl, Göran Engberg, Simon Cervenka, T Petteri Piepponen, Fu-Ping Zhang, Petra Sipilä, Johan Jakobsson, Carl M Sellgren, Sophie Erhardt, Jaan-Olle Andresso. Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia. Molecular psychiatry. 2022-05-26. PMID:35618883. |
presynaptic increase in striatal dopamine is the primary dopaminergic abnormality in schizophrenia, but the underlying mechanisms are not understood. |
2022-05-26 |
2023-08-13 |
mouse |
| Sofia Elizarova, Abed Alrahman Chouaib, Ali Shaib, Björn Hill, Florian Mann, Nils Brose, Sebastian Kruss, James A Danie. A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 22. 2022-05-25. PMID:35613050. |
significancethe neurotransmitter dopamine controls normal behavior and dopaminergic dysfunction is prevalent in multiple brain diseases. |
2022-05-25 |
2023-08-13 |
Not clear |
| E V Tipisova, I N Molodovskaya, V A Alikina, A E Elfimov. Distinctive features of the hypothalamic-pituitary-gonadal axis and the level of dopamine in men of the European and Asian North. Klinicheskaia laboratornaia diagnostika. vol 67. issue 5. 2022-05-25. PMID:35613343. |
the study of the dopamine levels and the content of sex hormones in the male population of various arctic regions is relevant due to the increased stress on the part of the dopaminergic system and the hypothalamic-pituitary-gonadal axis in residents of the northern regions, as well as the lack of information about their interaction among the apparently healthy population. |
2022-05-25 |
2023-08-13 |
Not clear |
| Mayank Patel, Shamsher Sing. Apigenin Attenuates Functional and Structural Alterations via Targeting NF-kB/Nrf2 Signaling Pathway in LPS-Induced Parkinsonism in Experimental Rats : Apigenin Attenuates LPS-Induced Parkinsonism in Experimental Rats. Neurotoxicity research. 2022-05-24. PMID:35608813. |
parkinson's disease (pd) is a progressive hypokinetic movement disorder caused by selective degeneration of dopaminergic neurons in striatum and dopamine deficiency in a region of the midbrain. |
2022-05-24 |
2023-08-13 |
rat |
| Iro Boura, Kallol Ray Chaudhur. Coronavirus Disease 2019 and Related Parkinsonism: The Clinical Evidence Thus Far. Movement disorders clinical practice. 2022-05-23. PMID:35601258. |
this theory is further augmented by reports of a pathogenic effect of the severe acute respiratory syndrome coronavirus-2 (sars-cov-2) on the central nervous system with specific impact on the dopaminergic pathway, as well as the possibility of the virus to selectively bind to angiotensin-converting enzyme-2 (ace-2); these molecules are expressed abundantly in the midbrain dopamine neurons and, are likely involved in several cellular mechanisms cited in parkinson's disease (pd) pathophysiology. |
2022-05-23 |
2023-08-13 |
Not clear |
| Tomoyo Shimada, Ryota Kamo, Kensuke Daida, Kenya Nishioka, Nobutaka Hattori, Taiji Tsunem. Radiation-induced Brain Calcification Leads to L-dopa-resistant Parkinsonism and Cerebellar Ataxia. Internal medicine (Tokyo, Japan). 2022-05-22. PMID:35598989. |
while dopamine transporter-single photon emission computed tomography revealed only slight damage to the dopaminergic striatal pathway, the extension of calcification to the periventricular white matter was likely responsible for her parkinsonism. |
2022-05-22 |
2023-08-13 |
Not clear |
| Pooriya Ghanbari Merdasi, Ramin Abdi Dezfouli, Sajad Mazaheri, Abbas Haghparas. Blocking the dopaminergic receptors in the hippocampal dentate gyrus reduced the stress-induced analgesia in persistent inflammatory pain in the rat. Physiology & behavior. 2022-05-21. PMID:35597308. |
this study aimed to investigate the role of dg dopaminergic receptors (d1- and d2-like dopamine receptors) in stress-induced analgesia (sia) using the formalin test as a persistent inflammatory pain model. |
2022-05-21 |
2023-08-13 |
rat |
| Francesca Montarolo, Serena Martire, Francesco Chiara, Sarah Allegra, Silvia De Francia, Eriola Hoxha, Filippo Tempia, Marco Alfonso Capobianco, Antonio Bertolott. NURR1-deficient mice have age- and sex-specific behavioral phenotypes. Journal of neuroscience research. 2022-05-20. PMID:35593070. |
the transcription factor nurr1 is essential to the generation and maintenance of midbrain dopaminergic (mda) neurons and its deregulation is involved in the development of dopamine (da)-associated brain disorders, such as parkinson's disease (pd). |
2022-05-20 |
2023-08-13 |
mouse |
| Giovanni Palermo, Sara Giannoni, Tommaso Depalo, Daniela Frosini, Duccio Volterrani, Gabriele Siciliano, Ubaldo Bonuccelli, Roberto Ceravol. Negative DAT-SPECT in Old Onset Parkinson's Disease: An Additional Pitfall? Movement disorders clinical practice. vol 9. issue 4. 2022-05-18. PMID:35582312. |
scans without evidence of dopaminergic deficit (swedds) refer to patients clinically diagnosed with parkinson's disease (pd), but showing normal findings on dopamine transporter single-photon emission computed tomography (dat-spect). |
2022-05-18 |
2023-08-13 |
Not clear |
| Ada Sinani, Andriana Vassi, Giota Tsotsokou, Maria Nikolakopoulou, Elias D Kouvelas, Ada Mitsaco. Early life stress influences basal ganglia dopamine receptors and novel object recognition of adolescent and adult rats. IBRO neuroscience reports. vol 12. 2022-05-16. PMID:35572456. |
it is known that the dopaminergic system undergoes significant reorganization during adolescence and that dopamine receptors are involved in recognition memory. |
2022-05-16 |
2023-08-13 |
rat |