| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I J Kopin, K S Bankiewicz, J Harvey-Whit. Assessment of brain dopamine metabolism from plasma HVA and MHPG during debrisoquin treatment: validation in monkeys treated with MPTP. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 1. issue 2. 1989-08-03. PMID:3266957. |
debrisoquin has been used to diminish peripheral formation of dopamine to enhance the value of plasma hva as an index of brain dopaminergic activity. |
1989-08-03 |
2023-08-11 |
monkey |
| S Denis-Donin. Expression of dopaminergic phenotypes in the mouse olfactory bulb induced by the calcitonin gene-related peptide. Nature. vol 339. issue 6227. 1989-08-02. PMID:2567962. |
to date the molecular signalling involved in this trans-synaptic induction has not yet been characterized; i have therefore studied the expression of dopaminergic properties (presence of th and dopamine uptake) in dissociated cell cultures from embryonic mouse olfactory bulb. |
1989-08-02 |
2023-08-11 |
mouse |
| A Carlsso. The current status of the dopamine hypothesis of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 1. issue 3. 1989-08-02. PMID:3075131. |
even though a disturbed dopamine function has not yet been established beyond doubt in schizophrenia, recent basic research on dopaminergic mechanisms opens up possibilities for the development of more sophisticated pharmacologic tools, capable of discovering subtypes of dopamine receptors, which may turn out to be abnormal in schizophrenia. |
1989-08-02 |
2023-08-11 |
Not clear |
| Z Gottesfeld, C J Garcia, R B Lingham, R B Chroniste. Prenatal ethanol exposure impairs lesion-induced plasticity in a dopaminergic synapse after maturity. Neuroscience. vol 29. issue 3. 1989-07-31. PMID:2567976. |
normally, in the olfactory tubercle, olfactory bulbectomy elicits alterations in pre- and postsynaptic dopaminergic markers, including, respectively, (1) increased tyrosine hydroxylase activity and immunoreactivity, which is associated with dopaminergic axon sprouting, and (2) increased dopaminergic receptor density and potentiated dopamine activation of adenylate cyclase. |
1989-07-31 |
2023-08-11 |
rat |
| R A Wallace, L Wallace, M Harrold, D Miller, N J Uretsk. Interaction of permanently charged chlorpromazine and dopamine analogs with the striatal D-1 dopaminergic receptor. Biochemical pharmacology. vol 38. issue 12. 1989-07-28. PMID:2525907. |
interaction of permanently charged chlorpromazine and dopamine analogs with the striatal d-1 dopaminergic receptor. |
1989-07-28 |
2023-08-11 |
Not clear |
| R A Wallace, L Wallace, M Harrold, D Miller, N J Uretsk. Interaction of permanently charged chlorpromazine and dopamine analogs with the striatal D-1 dopaminergic receptor. Biochemical pharmacology. vol 38. issue 12. 1989-07-28. PMID:2525907. |
although a structural feature common to all dopaminergic agonists and antagonists is a side-chain basic amino group, it is unclear whether this moiety binds to the d-1 dopamine (da) receptor in the charged or uncharged form. |
1989-07-28 |
2023-08-11 |
Not clear |
| M Iyo, T Yamasaki, H Fukuda, O Inoue, K Suzuki, H Shinotoh, T Ito, H Yonezawa, M Nishio, A Kosek. [Age-related decrease of 11C-N-methylspiperone in vivo binding to human striatum detected by PET]. Kaku igaku. The Japanese journal of nuclear medicine. vol 26. issue 2. 1989-07-27. PMID:2525202. |
these data suggested that the dopaminergic activity through d2 dopamine receptors reduces with aging in human striatum. |
1989-07-27 |
2023-08-11 |
human |
| T E Audesir. Characterization of pre- and postsynaptic dopamine receptors in Lymnaea. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 93. issue 1. 1989-07-19. PMID:2567221. |
rped1 is itself dopaminergic, implicating autoreceptors in its response to dopamine. |
1989-07-19 |
2023-08-11 |
Not clear |
| W J Free. An hypothesis regarding the antipsychotic effect of neuroleptic drugs. Pharmacology, biochemistry, and behavior. vol 32. issue 1. 1989-07-17. PMID:2567525. |
one effect of dopamine antagonists which develops slowly is dopaminergic supersensitivity. |
1989-07-17 |
2023-08-11 |
Not clear |
| A I Smith, C A Wallace, I J Clarke, J W Funde. Dopaminergic agents differentially regulate both processing and content of alpha-N-acetylated endorphin and alpha-MSH in the ovine pituitary intermediate lobe. Neuroendocrinology. vol 49. issue 5. 1989-07-12. PMID:2566941. |
to determine if these effects reflect the loss of descending dopaminergic neuronal input to the il, we have chronically treated two groups (n = 4 per group) of normal sheep with the dopamine antagonist haloperidol or the dopamine agonist bromocriptine; a group of hpd sheep were also treated with bromocriptine. |
1989-07-12 |
2023-08-11 |
Not clear |
| F Javoy-Agid, B Scatton, M Ruberg, R L'Heureux, P Cervera, R Raisman, J M Maloteaux, H Beck, Y Agi. Distribution of monoaminergic, cholinergic, and GABAergic markers in the human cerebral cortex. Neuroscience. vol 29. issue 2. 1989-07-07. PMID:2471113. |
markers for dopaminergic neurons (dopamine levels, dopamine/noradrenaline ratio and homovanillic acid levels) seemed denser in the prefrontal and temporal regions. |
1989-07-07 |
2023-08-11 |
human |
| S M Zimatki. [Aldehyde dehydrogenase activity in rat cerebral structures]. Arkhiv anatomii, gistologii i embriologii. vol 96. issue 1. 1989-07-05. PMID:2730352. |
a positive correlation is found between distribution of alddg activity among the forebrain structures, on the one hand, and density of dopaminergic terminals, dopamine content and mao activity of these structures--on the other. |
1989-07-05 |
2023-08-11 |
rat |
| G E Glynn, B K Yamamot. In vivo neurochemical and anatomical heterogeneity of the dopamine uptake system in the rat caudate putamen. Brain research. vol 481. issue 2. 1989-06-30. PMID:2524237. |
the regional gradients detected in dopamine uptake blockade may indicate a heterogeneous distribution in the number of uptake sites, a regional variation in the affinity of the uptake site for the blocker and/or altered neuronal activity mediated by an action of the blocker on dopaminergic cell bodies. |
1989-06-30 |
2023-08-11 |
rat |
| N Toda, H Okunishi, T Okamur. Responses to dopamine of isolated human gastroepiploic arteries. Archives internationales de pharmacodynamie et de therapie. vol 297. 1989-06-29. PMID:2658894. |
it may be concluded that dopamine contracts human gastroepiploic arteries of the proximal portion, due to a predominant activation of alpha-adrenoceptors, and dilates the distal arteries by acting preferentially on dopaminergic da1-receptors, possibly residing in smooth muscle. |
1989-06-29 |
2023-08-11 |
human |
| D D Miller, M Harrold, R A Wallace, L J Wallace, N J Uretsk. Dopaminergic drugs in the cationic form interact with D2 dopamine receptors. Trends in pharmacological sciences. vol 9. issue 8. 1989-06-27. PMID:2907954. |
dopaminergic drugs in the cationic form interact with d2 dopamine receptors. |
1989-06-27 |
2023-08-11 |
Not clear |
| R De Cotiis, C Lombardi, C Spedin. [Recent progress in dopaminergic control of aldosterone secretion]. Minerva medica. vol 80. issue 3. 1989-06-16. PMID:2566135. |
the role of dopamine on the aldosterone secretion-regulation mechanism has been confirmed by the identification of dopaminergic receptors on adrenal glomerulosa cells. |
1989-06-16 |
2023-08-11 |
Not clear |
| R De Cotiis, C Lombardi, C Spedin. [Recent progress in dopaminergic control of aldosterone secretion]. Minerva medica. vol 80. issue 3. 1989-06-16. PMID:2566135. |
the use of dopamine agonist and antagonist substances has shown that dopamine inhibits aldosterone biosynthesis by activating da2 dopaminergic receptors identified in adrenal glomerulosa cells. |
1989-06-16 |
2023-08-11 |
Not clear |
| R F Gariano, S F Sawyer, J M Tepper, S J Young, P M Grove. Mesocortical dopaminergic neurons. 2. Electrophysiological consequences of terminal autoreceptor activation. Brain research bulletin. vol 22. issue 3. 1989-06-15. PMID:2713724. |
measurement of drug- and stimulation-induced changes in the electrical excitability of dopaminergic terminals was employed to assess the effects of stimulation of dopamine terminal autoreceptors in the prefrontal cortex in urethane-anesthetized rats. |
1989-06-15 |
2023-08-11 |
rat |
| F Thibaut, J J Bonnet, J Costenti. Time course of postmortem modifications in synaptosomal [3H]dopamine uptake and [3H]GBR 12783 binding to the dopamine uptake complex in the rat striatum. Neuroscience letters. vol 96. issue 3. 1989-06-15. PMID:2717059. |
the present study focuses on the changes of two biochemical markers of the striatal dopaminergic innervation evaluated after different postmortem storage periods of rat heads either at room temperature (21 degrees c) or at 4 degrees c: (i) the uptake of [3h]dopamine (da) into striatal synaptosomes and (ii) the specific binding of [3h]gbr 12783, a selective ligand for the neuronal dopamine uptake sites, to a striatal membrane fraction. |
1989-06-15 |
2023-08-11 |
rat |
| T Di Paolo, F Bédard, P J Bédar. Influence of gonadal steroids on human and monkey cerebrospinal fluid homovanillic acid concentrations. Clinical neuropharmacology. vol 12. issue 1. 1989-06-14. PMID:2469538. |
the influence of gonadal steroids on central dopaminergic function was assessed by measuring concentrations of the dopamine metabolite homovanillic acid (hva) in cerebrospinal fluid (csf) in humans and monkeys. |
1989-06-14 |
2023-08-11 |
human |