| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Abeer Dagra, Douglas R Miller, Min Lin, Adithya Gopinath, Fatemeh Shaerzadeh, Sharonda Harris, Zachary A Sorrentino, Jonatan Fullerton Støier, Sophia Velasco, Janelle Azar, Adetola R Alonge, Joseph J Lebowitz, Brittany Ulm, Mengfei Bu, Carissa A Hansen, Nikhil Urs, Benoit I Giasson, Habibeh Khoshboue. α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability. NPJ Parkinson's disease. vol 7. issue 1. 2021-09-04. PMID:34408150. |
we found that overexpression of α-synuclein in mouse (male and female) dopaminergic neurons altered neuronal firing properties, calcium dynamics, dopamine release, protein expression, and morphology. |
2021-09-04 |
2023-08-13 |
mouse |
| Dana Mueller, Kameko Halfman. Dopamine, religiosity, and utilitarian moral judgment. Social neuroscience. 2021-09-03. PMID:34461025. |
we measured dopamine using spontaneous eyeblink rate, an indirect measure associated with striatal dopaminergic transmission. |
2021-09-03 |
2023-08-13 |
human |
| Dina M Monir, Motamed E Mahmoud, Omyma G Ahmed, Ibrahim F Rehan, Amany Abdelrahma. Forced exercise activates the NrF2 pathway in the striatum and ameliorates motor and behavioral manifestations of Parkinson's disease in rotenone-treated rats. Behavioral and brain functions : BBF. vol 16. issue 1. 2021-09-02. PMID:33158454. |
parkinson's disease (pd) is a common neurodegenerative disorder characterized by progressive loss of nigrostriatal dopaminergic neurons leading to dopamine depletion and problems of movement, emotions, and cognition. |
2021-09-02 |
2023-08-13 |
rat |
| Mustafa T Ardah, Greeshma Bharathan, Tohru Kitada, M Emdadul Haqu. Ellagic Acid Prevents Dopamine Neuron Degeneration from Oxidative Stress and Neuroinflammation in MPTP Model of Parkinson's Disease. Biomolecules. vol 10. issue 11. 2021-09-02. PMID:33172035. |
however, treatment with ea prior to mptp injection significantly rescued the dopaminergic neurons and dopamine transporter. |
2021-09-02 |
2023-08-13 |
Not clear |
| Débora Dreher Nabinger, Stefani Altenhofen, Júlia Vasconcellos Peixoto, Julia Maria Kuhl da Silva, Robert Gerlai, Carla Denise Bona. Feeding status alters exploratory and anxiety-like behaviors in zebrafish larvae exposed to quinpirole. Progress in neuro-psychopharmacology & biological psychiatry. vol 108. 2021-09-02. PMID:33212194. |
nutritional status can impact dopamine reuptake, receptor affinity, transporter activity, and the effects of drugs that bind to dopamine receptors or interact with dopaminergic system. |
2021-09-02 |
2023-08-13 |
human |
| Li Zou, Xingyu Zhang, Min Xiong, Lanxia Meng, Ye Tian, Lina Pan, Xin Yuan, Guiqin Chen, Zhihao Wang, Lihong Bu, Zhaohui Yao, Zhaohui Zhang, Keqiang Ye, Zhentao Zhan. Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease. Neurobiology of disease. vol 154. 2021-09-02. PMID:33677035. |
synaptic dysfunction impairs dopamine turnover and contributes to the degeneration of dopaminergic neurons. |
2021-09-02 |
2023-08-13 |
mouse |
| Gerly Tamm, Kairi Kreegipuu, Jaanus Harr. Platelet MAO activity and COMT Val158Met genotype interaction predicts visual working memory updating efficiency. Behavioural brain research. vol 407. 2021-09-02. PMID:33745984. |
the findings support the view that serotonin modulates dopaminergic activation in updating and contribute to understanding the role of serotonin in pfc, top-down inhibitory signals, and its interactions with dopamine in wm processes. |
2021-09-02 |
2023-08-13 |
human |
| Puneet K Sharma, Lisa Wells, Gaia Rizzo, Joanna L Elson, Jan Passchier, Eugenii A Rabiner, Roger N Gunn, David T Dexter, Ilse S Pienaa. DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 17. issue 3. 2021-09-01. PMID:31965550. |
stimulation of excitatory designer receptors exclusively activated by designer drugs expressed within ppn cholinergic neurons activated residual nigrostriatal dopaminergic neurons to produce profound motor recovery, which correlated with striatal dopamine efflux as well as restored dopamine receptor 1- and dopamine receptor 2-based medium spiny neuron activity, as was ascertained with c-fos-based immunohistochemistry and stereological cell counts. |
2021-09-01 |
2023-08-13 |
rat |
| Yuhei Mori, Itaru Miura, Michinari Nozaki, Yusuke Osakabe, Ryuta Izumi, Takahiro Akama, So Kimura, Hirooki Yab. Electroconvulsive Therapy for Parkinson's Disease with Depression and Neuroleptic Malignant Syndrome: A Case Report. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 19. issue 3. 2021-09-01. PMID:34294629. |
because advanced parkinson's disease can sometimes be refractory to treatment based on pharmacological treatment-induced dopamine dysfunction, psychiatrists often have difficulty treating psychiatric symptoms; electroconvulsive therapy may stabilize the dopaminergic system in such cases, presenting a possible non-pharmacologic treatment option for parkinson's disease. |
2021-09-01 |
2023-08-13 |
Not clear |
| Linlin Zhang, Yanan Zheng, Junxia Xie, Limin Sh. Potassium channels and their emerging role in parkinson's disease. Brain research bulletin. vol 160. 2021-08-31. PMID:32305406. |
parkinson's disease (pd) is the second most common neurodegenerative disorder, which is associated with a selective loss of dopaminergic neurons in the substantia nigra (sn) and a reduction of dopamine in the striatum. |
2021-08-31 |
2023-08-13 |
Not clear |
| Valtteri Kaasinen, Tero Vahlberg, A Jon Stoessl, Antonio P Strafella, Angelo Antonin. Dopamine Receptors in Parkinson's Disease: A Meta-Analysis of Imaging Studies. Movement disorders : official journal of the Movement Disorder Society. vol 36. issue 8. 2021-08-31. PMID:33955044. |
in pd, compensatory changes in dopamine receptors emerge as a consequence of the loss of dopamine nerve terminals or dopaminergic pharmacotherapy. |
2021-08-31 |
2023-08-13 |
human |
| Bryant J Jongkee. Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating. Cognitive, affective & behavioral neuroscience. vol 20. issue 3. 2021-08-30. PMID:32133585. |
these results are consistent with an inverted-u relationship between dopamine and wm, and they indicate that updating and gating are differentially affected by a dopaminergic manipulation. |
2021-08-30 |
2023-08-13 |
human |
| Rasem Mustafa, Chahinaz Rawas, Nadja Mannal, Grzegorz Kreiner, Björn Spittau, Katarzyna Kamińska, Rüstem Yilmaz, Christina Pötschke, Joachim Kirsch, Birgit Liss, Kerry L Tucker, Rosanna Parlat. Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress. Antioxidants (Basel, Switzerland). vol 10. issue 8. 2021-08-30. PMID:34439532. |
targeted ablation of primary cilia in differentiated dopaminergic neurons reduces striatal dopamine and responsiveness to metabolic stress. |
2021-08-30 |
2023-08-13 |
mouse |
| Arunkumar Singh Koijam, Aruna Chanu Hijam, Asem Surindro Singh, Preeti Jaiswal, Kanchan Mukhopadhyay, Usha Rajamma, Reena Haoba. Association of Dopamine Transporter Gene with Heroin Dependence in an Indian Subpopulation from Manipur. Journal of molecular neuroscience : MN. vol 71. issue 1. 2021-08-27. PMID:32557146. |
dopamine transporter (dat) or solute carrier family 6 member 3 (slc6a3) is a transmembrane protein regulating dopaminergic neurotransmission. |
2021-08-27 |
2023-08-13 |
Not clear |
| Chao Ren, Fen Wang, Kai-Jie He, Yu-Ting Zhang, Ling-Xi Li, Jin-Bao Zhang, Jing Chen, Cheng-Jie Mao, Chun-Feng Li. Early-life stress induces prodromal features of Parkinsonian with aging in rats. The journals of gerontology. Series A, Biological sciences and medical sciences. 2021-08-27. PMID:34448826. |
based on neuroimaging and histochemistry, although we found that the dopaminergic system in striatum was impaired after ms, the decrease of striatal dopamine level was ~33%. |
2021-08-27 |
2023-08-13 |
human |
| Caline S Karam, Brenna L Williams, Sandra K Jones, Jonathan A Javitc. The Role of the Dopamine Transporter in the Effects of Amphetamine on Sleep and Sleep Architecture in Drosophila. Neurochemical research. 2021-08-26. PMID:33630236. |
the dopamine transporter (dat) mediates the inactivation of released dopamine (da) through its reuptake, and thereby plays an important homeostatic role in dopaminergic neurotransmission. |
2021-08-26 |
2023-08-13 |
drosophila_melanogaster |
| Denis Pavăl, Ioana Valentina Micluți. The Dopamine Hypothesis of Autism Spectrum Disorder Revisited: Current Status and Future Prospects. Developmental neuroscience. vol 43. issue 2. 2021-08-25. PMID:34010842. |
in 2017, we provided a theoretical framework for a "dopamine hypothesis of asd" which proposed that autistic behavior arises from a dysfunctional midbrain dopaminergic system. |
2021-08-25 |
2023-08-13 |
Not clear |
| Nii A Add. An ongoing saga of nicotine complexity and dopamine heterogeneity: Nicotine activation and inhibition mediating reward and anxiety. Neuron. vol 109. issue 16. 2021-08-25. PMID:34411537. |
their findings provide new understanding of the functional role of ventral tegmental area (vta) dopamine neurons and reveal topographically distinct, pathway-specific, and opposite dopaminergic responses to nicotine that likely mediate reward and anxiety, respectively. |
2021-08-25 |
2023-08-13 |
Not clear |
| Mikhail Melnikov, Anastasiya Sviridova, Vladimir Rogovskii, Vladimir Kudrin, Vladimir Murugin, Alexey Boyko, Mikhail Pashenko. The role of D2-like dopaminergic receptor in dopamine-mediated modulation of Th17-cells in multiple sclerosis. Current neuropharmacology. 2021-08-25. PMID:34429055. |
in contrast, blockade of d2-like dopaminergic receptor by sulpiride decreased dopamine's inhibitory effect on il-17 secretion in both groups and gm-csf and il-21 production in ms patients. |
2021-08-25 |
2023-08-13 |
human |
| Mikhail Melnikov, Anastasiya Sviridova, Vladimir Rogovskii, Vladimir Kudrin, Vladimir Murugin, Alexey Boyko, Mikhail Pashenko. The role of D2-like dopaminergic receptor in dopamine-mediated modulation of Th17-cells in multiple sclerosis. Current neuropharmacology. 2021-08-25. PMID:34429055. |
these data suggest an inhibitory role of dopamine on th17-cells in ms, which could be mediated by the activation of d2-like dopaminergic receptor. |
2021-08-25 |
2023-08-13 |
human |