| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Beatriz I Gallego, Juan J Salazar, Rosa de Hoz, Blanca Rojas, Ana I Ramírez, Manuel Salinas-Navarro, Arturo Ortín-Martínez, Francisco J Valiente-Soriano, Marcelino Avilés-Trigueros, Maria P Villegas-Perez, Manuel Vidal-Sanz, Alberto Triviño, Jose M Ramíre. IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma. Journal of neuroinflammation. vol 9. 2013-06-10. PMID:22583833. |
iop induces upregulation of gfap and mhc-ii and microglia reactivity in mice retina contralateral to experimental glaucoma. |
2013-06-10 |
2023-08-12 |
mouse |
| Wenxin Ma, Steven Coon, Lian Zhao, Robert N Fariss, Wai T Won. A2E accumulation influences retinal microglial activation and complement regulation. Neurobiology of aging. vol 34. issue 3. 2013-05-24. PMID:22819137. |
in the aging retina, microglia aggregate in the outer retina and acquire intracellular autofluorescent lipofuscin deposits. |
2013-05-24 |
2023-08-12 |
Not clear |
| Wenxin Ma, Steven Coon, Lian Zhao, Robert N Fariss, Wai T Won. A2E accumulation influences retinal microglial activation and complement regulation. Neurobiology of aging. vol 34. issue 3. 2013-05-24. PMID:22819137. |
taken together, our findings highlight the role of microglia in the local control of complement activation in the retina and present the age-related accumulation of ocular lipofuscin in subretinal microglia as a cellular mechanism capable of driving outer retinal immune dysregulation in age-related macular degeneration pathogenesis. |
2013-05-24 |
2023-08-12 |
Not clear |
| Debra A Carter, Balini Balasubramaniam, Andrew D Dic. Functional analysis of retinal microglia and their effects on progenitors. Methods in molecular biology (Clifton, N.J.). vol 935. 2013-04-17. PMID:23150375. |
utilizing human postmortem retina, we have created a research platform to isolate, culture, and characterize adult retinal microglia as well as analyze their effect on retinal progenitors. |
2013-04-17 |
2023-08-12 |
human |
| Ruth Bejarano-Escobar, Manuel Blasco, Gervasio Martín-Partido, Javier Francisco-Morcill. Light-induced degeneration and microglial response in the retina of an epibenthonic pigmented teleost: age-dependent photoreceptor susceptibility to cell death. The Journal of experimental biology. vol 215. issue Pt 21. 2013-04-15. PMID:22811246. |
specific labelling of microglial cells with griffonia simplicifolia lectin (gsl) histochemistry revealed that photoreceptor cell death alerts microglia in the degenerating retina, leading to local proliferation, migration towards the injured outer nuclear layer (onl), and enhanced phagocytosis of photoreceptor debris. |
2013-04-15 |
2023-08-12 |
Not clear |
| Ulrich F O Luhmann, Livia S Carvalho, Scott J Robbie, Jill A Cowing, Yanai Duran, Peter M G Munro, James W B Bainbridge, Robin R Al. Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration. Experimental eye research. vol 107. 2013-03-27. PMID:23232206. |
in conclusion, ccl2-ccr2 and/or cx3cl1-cx3cr1 signalling defects may differentially affect the trafficking of microglia and macrophages in the retina during ageing, but do not appear to cause age-related retinal degeneration in mice. |
2013-03-27 |
2023-08-12 |
mouse |
| Congrong Guo, Atsushi Otani, Akio Oishi, Hiroshi Kojima, Yukiko Makiyama, Satoko Nakagawa, Nagahisa Yoshimur. Knockout of ccr2 alleviates photoreceptor cell death in a model of retinitis pigmentosa. Experimental eye research. vol 104. 2013-01-25. PMID:23022404. |
photoreceptor apoptosis (tunel staining) and the number of microglia (positive for the f4/80 antibody) in the retina were examined. |
2013-01-25 |
2023-08-12 |
mouse |
| Qing-ling Fu, Yu Zhang, Yi-hua Su, Yue-qi Sun, Shu-juan Sun, Jian-bo Sh. [Increasing expression of microglia in the retina after optic nerve transection in rats]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology. vol 47. issue 12. 2013-01-07. PMID:22336117. |
[increasing expression of microglia in the retina after optic nerve transection in rats]. |
2013-01-07 |
2023-08-12 |
rat |
| Mei Chen, Jiawu Zhao, Chang Luo, Sudha Priya Soundara Pandi, Rosana G Penalva, Denise C Fitzgerald, Heping X. Para-inflammation-mediated retinal recruitment of bone marrow-derived myeloid cells following whole-body irradiation is CCL2 dependent. Glia. vol 60. issue 5. 2012-11-19. PMID:22362506. |
both resident microglia and bm-derived phagocytes displayed mild activation in the neuronal retina following irradiation. |
2012-11-19 |
2023-08-12 |
mouse |
| Holly R Chinnery, Samuel McLenachan, Timothy Humphries, Jelena M Kezic, Xiangting Chen, Marc J Ruitenberg, Paul G McMenami. Accumulation of murine subretinal macrophages: effects of age, pigmentation and CX3CR1. Neurobiology of aging. vol 33. issue 8. 2012-10-24. PMID:21570740. |
we investigated the effects of age, pigmentation and cx(3)cr1 deficiency on the accumulation of macrophages/activated microglia in the outer retina of young and old cx(3)cr1(gfp/gfp) (cx(3)cr1-deficient) or cx(3)cr1(gfp/+) mice on either a pigmented (c57bl/6) or albino (balb/c) background. |
2012-10-24 |
2023-08-12 |
mouse |
| Jong-Hyun Lee, Hyo-Suk Park, Ji Man Shin, Myung-Hoon Chun, Su-Ja O. Nestin expressing progenitor cells during establishment of the neural retina and its vasculature. Anatomy & cell biology. vol 45. issue 1. 2012-10-02. PMID:22536550. |
thus, müller glial cells might be potential neural progenitor cells of the retina, and the retinal microvasculature established by both the endothelial and the pericyte progenitor cells via vasculogenesis along microglia migrating routes sustains its angiogenic potential. |
2012-10-02 |
2023-08-12 |
Not clear |
| Tao Huang, Jianlin Cui, Lei Li, Peter F Hitchcock, Yuhao L. The role of microglia in the neurogenesis of zebrafish retina. Biochemical and biophysical research communications. vol 421. issue 2. 2012-07-09. PMID:22497888. |
the role of microglia in the neurogenesis of zebrafish retina. |
2012-07-09 |
2023-08-12 |
zebrafish |
| Tao Huang, Jianlin Cui, Lei Li, Peter F Hitchcock, Yuhao L. The role of microglia in the neurogenesis of zebrafish retina. Biochemical and biophysical research communications. vol 421. issue 2. 2012-07-09. PMID:22497888. |
in zebrafish, early macrophages migrate from the yolk sac to the brain and retina at 26-30 hour post fertilization (hpf) and transform into microglia at 55-60 hpf. |
2012-07-09 |
2023-08-12 |
zebrafish |
| Tao Huang, Jianlin Cui, Lei Li, Peter F Hitchcock, Yuhao L. The role of microglia in the neurogenesis of zebrafish retina. Biochemical and biophysical research communications. vol 421. issue 2. 2012-07-09. PMID:22497888. |
when embryos were allowed to survive beyond the time when morpholino-dependent translation inhibition is lost, microglia re-occupy the retina and neuronal differentiation partially recovers. |
2012-07-09 |
2023-08-12 |
zebrafish |
| D R Howlett, S T Bate, S Collier, A Lawman, T Chapman, T Ashmeade, I Marshall, P J B Anderson, K L Philpott, J C Richardson, C J Hill. Characterisation of amyloid-induced inflammatory responses in the rat retina. Experimental brain research. vol 214. issue 2. 2012-06-26. PMID:21850448. |
histology and mrna endpoints in the retina demonstrate aβ1-42-, but not aβ42-1-, induced inflammatory responses characterised by increases in markers for microglia and astrocytes (ionised calcium-binding adaptor molecule 1 (iba-1), gfap and nestin) and increases in mrna for inflammatory cytokines and chemokines such as il1-β, mip1α and tnfα. |
2012-06-26 |
2023-08-12 |
rat |
| Richard Fairless, Sarah K Williams, Dorit B Hoffmann, Aleksandar Stojic, Sonja Hochmeister, Frank Schmitz, Maria K Storch, Ricarda Die. Preclinical retinal neurodegeneration in a model of multiple sclerosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 16. 2012-06-12. PMID:22514320. |
in addition, we observed an early activation of resident microglia in the retina. |
2012-06-12 |
2023-08-12 |
rat |
| Neal D Heuss, Ute Lehmann, Christopher C Norbury, Scott W McPherson, Dale S Gregerso. Local activation of dendritic cells alters the pathogenesis of autoimmune disease in the retina. Journal of immunology (Baltimore, Md. : 1950). vol 188. issue 3. 2012-06-11. PMID:22219322. |
we recently reported that dendritic cells (dc) distinct from microglia were present in quiescent retina and rapidly responded to injured neurons. |
2012-06-11 |
2023-08-12 |
Not clear |
| Raymond Iezzi, Bharath R Guru, Inna V Glybina, Manoj K Mishra, Alexander Kennedy, Rangaramanujam M Kanna. Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration. Biomaterials. vol 33. issue 3. 2012-05-29. PMID:22048009. |
we show that, upon intravitreal administration, pamam dendrimers selectively localize within activated outer retinal microglia in two rat models of retinal degeneration, but not in the retina of healthy controls. |
2012-05-29 |
2023-08-12 |
rat |
| Wenxin Ma, Lian Zhao, Wai T Won. Microglia in the outer retina and their relevance to pathogenesis of age-related macular degeneration. Advances in experimental medicine and biology. vol 723. 2012-04-13. PMID:22183313. |
microglia in the outer retina and their relevance to pathogenesis of age-related macular degeneration. |
2012-04-13 |
2023-08-12 |
Not clear |
| Jerome E Roger, Keerthi Ranganath, Lian Zhao, Radu I Cojocaru, Matthew Brooks, Norimoto Gotoh, Shobi Veleri, Avinash Hiriyanna, Rivka A Rachel, Maria Mercedes Campos, Robert N Fariss, Wai T Wong, Anand Swaroo. Preservation of cone photoreceptors after a rapid yet transient degeneration and remodeling in cone-only Nrl-/- mouse retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 2. 2012-03-06. PMID:22238088. |
here, we report that nrl(-/-) retina undergoes a rapid but transient period of degeneration in early adulthood, with cone apoptosis, retinal detachment, alterations in retinal vessel structure, and activation and translocation of retinal microglia. |
2012-03-06 |
2023-08-12 |
mouse |